For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. leprae Br4923 MLBr_01756 (-)

annotation: putative multidrug resistance protein
coordinates: 2131218 - 2131541
length: 107

VAYLFLFCAIFVEVVATTLLKSTEGFTRLVPTLACLAGYAVTFTLLALSISRGMKTDVAYALWSAIGTAA
IVLIAVLFLDSPVSVAKVVGVALIIVGVITLNLADAH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01756--100% (107)putative multidrug resistance protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3092mmr3e-4379.05% (105) multidrugs-transport integral membrane protein MMR
M. gilvum PYR-GCKMflv_3553-9e-1336.11% (108) small multidrug resistance protein
M. tuberculosis H37RvRv3065mmr3e-4379.05% (105) multidrugs-transport integral membrane protein MMR
M. abscessus ATCC 19977MAB_2640c-3e-1129.81% (104) putative multidrug resistance protein
M. marinum MMMAR_1612mmr4e-3568.22% (107) multidrug-transport integral membrane protein Mmr
M. avium 104MAV_3949-4e-4277.57% (107) transporter, small multidrug resistance (SMR) family protein
M. smegmatis MC2 155MSMEG_3672-1e-1639.42% (104) transporter, small multidrug resistance (SMR) family protein
M. thermoresistible (build 8)TH_2224-2e-1640.00% (95) transporter, small multidrug resistance (SMR) family protein
M. ulcerans Agy99MUL_3425mmr2e-3467.29% (107) multidrug-transport integral membrane protein Mmr
M. vanbaalenii PYR-1Mvan_0339-2e-3060.75% (107) small multidrug resistance protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3092|M.bovis_AF2122/97            -------MIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAF
Rv3065|M.tuberculosis_H37Rv         -------MIYLYLLCAIFAEVVATSLLKSTEGFTRLWPTVGCLVGYGIAF
MLBr_01756|M.leprae_Br4923          -------MAYLFLFCAIFVEVVATTLLKSTEGFTRLVPTLACLAGYAVTF
MAV_3949|M.avium_104                MRARGGVLTYLFLICAILAEVVATSLLKSTQGFTRLWPTVICLLGYAVSF
MMAR_1612|M.marinum_M               -------MAYLLLLGAIAMEVMATSFLKSTEGFTRLWPTVICLTVYGFSF
MUL_3425|M.ulcerans_Agy99           -------MAYLLLLGAIAMEVMATSFLKSTEGFTRLWPTVICLTIYGFSF
Mvan_0339|M.vanbaalenii_PYR-1       ----MPGVAWTLLGGAILAEVIATSMLKSTEGFTRLWPTLACLLLYGAAF
MAB_2640c|M.abscessus_ATCC_199      -------MVWLVLVLAGLLEVGWAIGLKYTEGFTRLWPTVGTVGSMIISI
MSMEG_3672|M.smegmatis_MC2_155      -------MMWLALAGAILVEVVATLSLRASDGFRRRAWIVPVVIGYAASF
TH_2224|M.thermoresistible__bu      --------MWWVLAGAILMEVAATLSLRASEGFRRKIWIVPVVAGYTASF
Mflv_3553|M.gilvum_PYR-GCK          ------MIEYVLLIAAIGCEVSATLALRVAARG-RTSFYGIVLIGYVAAF
                                             :  *  *   **  :  *: :    *       :     ::

Mb3092|M.bovis_AF2122/97            ALLALSISHGMQTDVAYALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGL
Rv3065|M.tuberculosis_H37Rv         ALLALSISHGMQTDVAYALWSAIGTAAIVLVAVLFLGSPISVMKVVGVGL
MLBr_01756|M.leprae_Br4923          TLLALSISRGMKTDVAYALWSAIGTAAIVLIAVLFLDSPVSVAKVVGVAL
MAV_3949|M.avium_104                ALLAVSISRGMQTDVAYALWSAIGTALIVLIAVLFLGSPISVTKVVGVGL
MMAR_1612|M.marinum_M               AMLAMSIARGMQTDVAYALWSAIGTGAIVLIAVLFLGSHLSLTKVLGVGL
MUL_3425|M.ulcerans_Agy99           AMLAMSTARGMQTDVAYALWSAIGTGAIVLIVVLFLGSHLSLTKVLGVGL
Mvan_0339|M.vanbaalenii_PYR-1       MLLAQSISHGMQVGIAYALWSAIGTTVIVAVGVTFLGEPISTLKVIGVAL
MAB_2640c|M.abscessus_ATCC_199      ALLGIAMKS-LPVGTAYAIWVGVGAVGTAILGIVLFGDSANVWRLLSLGL
MSMEG_3672|M.smegmatis_MC2_155      YLLWVALSLGVPVGVAYGIWTACGVALVAVVARILFRDPLTPMMMLGIAL
TH_2224|M.thermoresistible__bu      ALLWWTLALGMPVGVAYGIWTACGVALIALIARWLFAEPLTRTTLLGIAL
Mflv_3553|M.gilvum_PYR-GCK          TLLWASLRHGMPLGVAYGIWAAAGVALTAAFSRLLFDEPLTRKMLGGIAL
                                     :*  :    :  . **.:* . *.   . .   :: .  .   : .:.*

Mb3092|M.bovis_AF2122/97            IVVGVVTLNLAGAH-
Rv3065|M.tuberculosis_H37Rv         IVVGVVTLNLAGAH-
MLBr_01756|M.leprae_Br4923          IIVGVITLNLADAH-
MAV_3949|M.avium_104                IIAGVVTLNLTGAH-
MMAR_1612|M.marinum_M               IIGGVLTLNLTGAH-
MUL_3425|M.ulcerans_Agy99           IIGGVLTLNLTGAH-
Mvan_0339|M.vanbaalenii_PYR-1       VVSGVVTLQLDGHQA
MAB_2640c|M.abscessus_ATCC_199      IVAGIIGLKLAT---
MSMEG_3672|M.smegmatis_MC2_155      IASGVFTIELAGVTH
TH_2224|M.thermoresistible__bu      IVAGVLTIEVFGGVH
Mflv_3553|M.gilvum_PYR-GCK          IMVGVLLVEIG-ASH
                                    :  *:. :::