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MAAPRIGVIGAGIVGLAVARRLQQKLQADVTVLDKENVVAAHQTGHNSNVVHSGVYYPPGSLKATLCRRG VGLLRAYCMERGLPYDELGKVIVAVQTDELPRLHDLAKRAVDNGIPDTRVIDRAELREREPHVDGLAALL IPSTAVVSFPAIAEEFRADIEAAGGQFRLGSPAVGIASRDGGVVITTDTDEFVFDHVVVCAGLQSSMIAE MAGAPRDPEIIPFRGEYYSLVASRSDLVKGLVYPVPDPRYPFLGVHFTRGIDGHVHVGPNAVLALAQEGY RWRDVNVRQLWRSVSYPGMLRLARHHWRMGASEIVGSMSKSVFLRRARAYIPELTASDIVRAESGVRAQA LKPDGNLVDDFVIHRLAGMTFVRNAPSPAATASLAIAEHIVDALA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1379 | - | - | 100% (395) | hypothetical protein MSMEG_1379 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3531 | - | 1e-112 | 54.18% (395) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4420 | gcvT_2 | 3e-06 | 25.12% (215) | aminomethyltransferase GcvT_2 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0204 | - | 1e-103 | 48.72% (392) | hypothetical protein Mvan_0204 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1379|M.smegmatis_MC2_155 MAAPRIGVIGAGIVGLAVARRLQQK-LQADVTVLDKENVVAAHQTGHNSN
Mflv_3531|M.gilvum_PYR-GCK -MVERVAVVGGGILGVAVARELTRRSPEAAVTVFEKEDRLASHQTGCNSG
Mvan_0204|M.vanbaalenii_PYR-1 MAALRVAVVGGGIVGLAVARELLHSIDGARVTVFEKESGVARHQTGHNSG
MMAR_4420|M.marinum_M -MGPKIVIVGAGIVGASLADELTARGVIDVTVVDRGPLFTTGGSTSHAPG
:: ::*.**:* ::* .* ..* : .*. ..
MSMEG_1379|M.smegmatis_MC2_155 VVHSGVYYPPGSLKATLCRRGVGLLRAYCMERGLPYDELGKVIVAVQTDE
Mflv_3531|M.gilvum_PYR-GCK VVHAGLYYEPGSAKAVLCRRGVGLLEQYCAEHAIERIACGKVLVARDEHE
Mvan_0204|M.vanbaalenii_PYR-1 VVHAGLYYAPGSLKARLCRRGVHLLREYLAQKDIRYSECGKIVVAHTAGD
MMAR_4420|M.marinum_M LVFA---TNPSKTMSAFARYTVDKFSGLHHRDGAVFNRVGGLEVATTAER
:*.: *.. : :.* * : . * : **
MSMEG_1379|M.smegmatis_MC2_155 LPRLHDLAKRAVDNGIPDTRVIDRAELREREPHVDG---LAALLIPSTAV
Mflv_3531|M.gilvum_PYR-GCK RARLTGIEDRARANGVPGVRVIGPAELREIEPHVRG---VAGLHSPSTSI
Mvan_0204|M.vanbaalenii_PYR-1 AARLAGIHERALANGVPGVRLVDAGEITDIEPHARG---ISALHSPSTAI
MMAR_4420|M.marinum_M WADLHRKAGWAQAWGVPG-RLVGPDQCVELHPLLDRAGILGGFHTPSDGL
. * * *:*. *::. : : .* :..: ** .:
MSMEG_1379|M.smegmatis_MC2_155 VSFPAIAEEFRADIEAAGGQFRLGSPAVGIASRDGGVVITTDT----DEF
Mflv_3531|M.gilvum_PYR-GCK VDFAAVTRSLADDARAAGAEILLGREVTGMRLHATEVVVRTQTPDGVAER
Mvan_0204|M.vanbaalenii_PYR-1 VDYPAVAEALAVDIADAGGEVLCDHGVIGMRRHGTEVVVTTAA----TSG
MMAR_4420|M.marinum_M ASAVRAVEAQARRAIARGAVFLAETEVQRVADHNGLVTGVHTSR---GVI
.. .. *. . . : : *. :
MSMEG_1379|M.smegmatis_MC2_155 VFDHVVVCAGLQSSMIAEMAG-----------------------------
Mflv_3531|M.gilvum_PYR-GCK PFDRVVACGGLQSDRLAEMAG-----------------------------
Mvan_0204|M.vanbaalenii_PYR-1 AFDVVVTCAGLQSDRVARMFG-----------------------------
MMAR_4420|M.marinum_M EADIVVCAAGFWGAQLAKQVGLVLPLVPMAHQYAKTGQVAPLVGRNTEDA
* ** ..*: . :*. *
MSMEG_1379|M.smegmatis_MC2_155 ---------------------------------------------APRDP
Mflv_3531|M.gilvum_PYR-GCK ---------------------------------------------DGPEP
Mvan_0204|M.vanbaalenii_PYR-1 ---------------------------------------------DSSSP
MMAR_4420|M.marinum_M PASLPILRHQDGDLYFREHVDRLGIGSYGHQPMPVDMSTLLADTAGEPMP
*
MSMEG_1379|M.smegmatis_MC2_155 EIIPFRGEYYS------------LVASRSDLVKGLVYPVPDPRYPFLGVH
Mflv_3531|M.gilvum_PYR-GCK VIMPFRGEYYA------------LRPERRGLVNGLVYPVPDPRYPFLGVH
Mvan_0204|M.vanbaalenii_PYR-1 RIVPFFGDYFL------------LHEAKSDMVNGLIYPVPDPRYPFLGVH
MMAR_4420|M.marinum_M SMLPFTEEDFEPAWRECVRLLPALGDTKVDEGFNGIFSFTPDGYSLLGEH
::** : : * : . . ::... *.:** *
MSMEG_1379|M.smegmatis_MC2_155 FTRG---IDGHVHVGPNAVLALAQEGYRWR-----DVNVRQLWRSVSYPG
Mflv_3531|M.gilvum_PYR-GCK LTPR---VDGEVLIGPNAVLALAREGYTWR-----DVSASDLAGVARTPA
Mvan_0204|M.vanbaalenii_PYR-1 LTKH---VDGRVSLGPNAFLAPGREAYTRG-----GWSARDVAAAVGFPG
MMAR_4420|M.marinum_M RELGGFWVAEAVWVTHSAGVAKAVAEWIVDGTPSIDVHECDLYRFEDFAR
: * : .* :* . : . :: .
MSMEG_1379|M.smegmatis_MC2_155 MLRLARHHWRMGASEIVGSMS-----------------------------
Mflv_3531|M.gilvum_PYR-GCK FWRFARRHWRTGITEMYGSLS-----------------------------
Mvan_0204|M.vanbaalenii_PYR-1 FWRFAVRNTAAAVREARTVMS-----------------------------
MMAR_4420|M.marinum_M SPRFIDETCAQAFVEVYDIVHPHQYRSALRGLRTSPFHHRQRELGAYFYE
*: . . * :
MSMEG_1379|M.smegmatis_MC2_155 -----KSVFLRRARAYIPELTASDIVRAESG-------------------
Mflv_3531|M.gilvum_PYR-GCK -----RRRFVAAARAYVPELGDDDVVPARAG-------------------
Mvan_0204|M.vanbaalenii_PYR-1 -----RAAFVREAQKYVPDVSVDDVVRGPRG-------------------
MMAR_4420|M.marinum_M GGGWERPAWFQANAELVRELAGRNVAFPERDDWAARYWSPIAIAEAQWTR
: :. : :: ::. .
MSMEG_1379|M.smegmatis_MC2_155 ----------------------------------------VRAQALKPDG
Mflv_3531|M.gilvum_PYR-GCK ----------------------------------------VRAQALDPDG
Mvan_0204|M.vanbaalenii_PYR-1 ----------------------------------------IRAQAMNADG
MMAR_4420|M.marinum_M ERVALYDMTPLTRYEVSGAGAVDLLQRLTTNDIDKGVGSVTYTLMLDETG
: :. *
MSMEG_1379|M.smegmatis_MC2_155 NLVDDFVIHRLAGMTFVRNAPSP----------------------AATAS
Mflv_3531|M.gilvum_PYR-GCK GLVDDFRISVRDRIVVLRNAPSP----------------------AATSA
Mvan_0204|M.vanbaalenii_PYR-1 TLEDDFVITGTDKVIHLRNAPSP----------------------GATSS
MMAR_4420|M.marinum_M GIRSDLTVARLGTARFQVGANGPQDFDWLSRHLPQDGSVTLRDITGATCC
: .*: : .* .* .**..
MSMEG_1379|M.smegmatis_MC2_155 LAIAEHIVDALA--------------------------------------
Mflv_3531|M.gilvum_PYR-GCK LAIAEHVVTAVLGEDDQRR-------------------------------
Mvan_0204|M.vanbaalenii_PYR-1 LAIAEYIVGTVVPARLGA--------------------------------
MMAR_4420|M.marinum_M IGVWGPAARDLVQPLCRDDLSHQAFPYFRLLQTYLEAIPVTMLRVSYVGE
:.: . :
MSMEG_1379|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3531|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0204|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4420|M.marinum_M LGWEIYTEASYGGALWDLLWAAGAGHQAIAAGRIAFNSLRMEKGYRAWGT
MSMEG_1379|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3531|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0204|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4420|M.marinum_M DMTAEHRPDEAGLGFAVRMSKDFIGKAALVDAAARKVLQCLVFDDPAAAA
MSMEG_1379|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3531|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0204|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4420|M.marinum_M LGKEPVLAGDVCIGFVTSAGYSPTIGRTIAYAWLPAESSIGDTVTVDHRG
MSMEG_1379|M.smegmatis_MC2_155 ----------------------
Mflv_3531|M.gilvum_PYR-GCK ----------------------
Mvan_0204|M.vanbaalenii_PYR-1 ----------------------
MMAR_4420|M.marinum_M RRYPASVHQQPVVDPESTRIRR