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M. smegmatis MC2 155 MSMEG_1183 (hutH)

annotation: histidine ammonia-lyase
coordinates: 1245061 - 1246605
length: 514

MTTVTVKVGVGPLAPSDVLHVARDNALVVLTPDASAAIAKSRDAVEQLAQAPVPAYGVSTGFGALATRHV
APELRVALQKSLVRSHAAGTGPEVEREVVRAMMLLRLSTLATGHTGIRPQTAELMAAMLSAGITPVVREY
GSLGCSGDLAPLAHCALALMGEGEVRDASGTLRPAADALAAAGLQPVQLSEKEGLALINGTDGMLGMLIL
AQHDLAMLLKTADIAAAMSVEALLGTDRVFADDLQALRPHPGQRTSASNLRRLLADSAIMESHRGPDCTV
VQDAYSLRCSPQVHGAAHDTLEHTRMVAARELAAAVDNPVVLHDGRVESNGNFHGAPIGYALDFLAIPVA
DVASMSERRTDRLLDPSRNKGLPPFLADDPGVDSGHMIAQYTQASIVSELKRLATPASVDSIPSSAMQED
HVSMGWSSARKLRRAVDGLKNVLAIEILTAARALDLRAPLTPAPATAAVVKALRDHVAGPGPDRFLAPEI
EAAATMVGTGAMVAAAESAIGALH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1183hutH-100% (514)histidine ammonia-lyase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3656-5e-0525.21% (242) NLP/P60 protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_1183|M.smegmatis_MC2_155      MTTVTVKVGVGPLAPSDVLHVARDNALVVLTPDASAAIAKSRDAVEQLAQ
Mvan_3656|M.vanbaalenii_PYR-1       MRRLTSLLIAGVLASMLVLHTSG-----VATAGHGSEPDGDSETVAGLVA
                                    *  :*  : .* **.  ***.:      * *.. .:    . ::*  *. 

MSMEG_1183|M.smegmatis_MC2_155      APVPAYGVSTGFGALATRHVAPELRVALQKSLVRSHAAGTGPEVEREVVR
Mvan_3656|M.vanbaalenii_PYR-1       AVAEVN------------QHVADIGADIQH-------------MQESVNR
                                    * . .             : ..:: . :*:             ::..* *

MSMEG_1183|M.smegmatis_MC2_155      AMMLLRLSTLATGHTGIRPQTAELMAAMLSAGITPVVREYGSLGCSGDLA
Mvan_3656|M.vanbaalenii_PYR-1       ALVELATAREAVSEAHRRLADSEKALADSQTAIDATQQRFDEFAASTYMN
                                    *:: *  :  *...:  *   :*   *  .:.* .. :.:..:..*  : 

MSMEG_1183|M.smegmatis_MC2_155      PLAHCALALMGEGEVRDASGTLRPAADALAAAGLQPVQLSEKEGLALING
Mvan_3656|M.vanbaalenii_PYR-1       GPSRSLPLASSPEDILSAASTQQ---TYLLAFGRVKDDLRRSQ-----TE
                                      ::.     .  :: .*:.* :     * * *    :* ..:     . 

MSMEG_1183|M.smegmatis_MC2_155      TDGMLGMLILAQHDLAMLLKTADIAAAMSVEALLGTDRVFADDLQALRPH
Mvan_3656|M.vanbaalenii_PYR-1       RANRLSAAKQARLDADAAAAEAQRRQDGAVAELVAAQRAFTNQQSDLTRL
                                      . *.    *: *       *:     :*  *:.::*.*::: . *   

MSMEG_1183|M.smegmatis_MC2_155      PGQRTSASNLRRLLADSAIMESHRGPDCTVVQDAYSLRCSPQVHGAAHDT
Mvan_3656|M.vanbaalenii_PYR-1       AAERDSAQ--TRLTTARPVAATTRQP--TAAQPGTPVPPSGQWDRSSPAP
                                    ..:* **.   ** :  .:  : * *  *..* . .:  * * . ::  .

MSMEG_1183|M.smegmatis_MC2_155      LEHTRMVAARELAAAVDNPVVLHDGRVESNGNFHGAPIGYALDFLAIPVA
Mvan_3656|M.vanbaalenii_PYR-1       ADSSGTGQWDTTLPMVP------------SANVAGDPIAIINAVLKIMAT
                                     : :         . *             ..*. * **.    .* * .:

MSMEG_1183|M.smegmatis_MC2_155      DVASMSERRTDRLLDPSRNKGLPPFLADDPGVDSGHMIAQYTQAS----I
Mvan_3656|M.vanbaalenii_PYR-1       SLQLTADMGRNFLTKLGILS--PATAAADPGITNGRIPRLYGRQASEFVI
                                    .:   ::   : * . .  .  *.  * ***: .*::   * : :    *

MSMEG_1183|M.smegmatis_MC2_155      VSELKRLATPASVDS----IPSSAMQEDHVSMGWSSARKLRRAVDGLKNV
Mvan_3656|M.vanbaalenii_PYR-1       RRAMSQLGVPYSWGGGNANGPSRGIDQGANTVGFDCSGLMLYAFAGVG--
                                       :.:*..* * ..     ** .:::.  ::*:..:  :  *. *:   

MSMEG_1183|M.smegmatis_MC2_155      LAIEILTAARALDLRAPLTPAPATAAVVKALRDHVAGPGPDRFLAPEIEA
Mvan_3656|M.vanbaalenii_PYR-1       --IKLDHYSGSQYNAGRKVPSSQMQRGDLIFYGPNASQHEAMYLGDGMMI
                                      *::   : :    .  .*:.        : .  *.     :*.  :  

MSMEG_1183|M.smegmatis_MC2_155      AATMVGTGAMVAAAESAIGALH-------
Mvan_3656|M.vanbaalenii_PYR-1       EAPYTGSVVKISPVRSSGMTPYVTRLIEY
                                     *. .*: . ::...*:  : :