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MTWNPHANRLKTFLLLVGMSGLIVFVGSLFGRNVMFLAVLFAVGMNAYVYFNSDKLALRAMHAQPITEVQ APEIYRIVRELATTAHQPMPRLYISDTANPNAFATGRNPRNAAVCCTTGILQLLNERELRAVLGHELSHV YNRDILISCVAGAMASVITALANMAMFAGMFGGNREGGNPLALLLVSFLGPIAATVVKLAVSRSREYQAD QSGAELTGDPLALASALRKISGGVEAAPLPPQPQLADQAHLMIASPFRAGERIGKLFSTHPPIADRIRRL EDMAGRGGSRPDSYY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1134 | - | - | 100% (295) | heat shock protein HtpX |
| M. smegmatis MC2 155 | MSMEG_3476 | - | 1e-04 | 23.76% (202) | peptidase, M48 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0578 | htpX | 1e-140 | 85.92% (284) | heat shock protein HtpX |
| M. gilvum PYR-GCK | Mflv_5252 | - | 1e-142 | 86.46% (288) | heat shock protein HtpX |
| M. tuberculosis H37Rv | Rv0563 | htpX | 1e-140 | 85.92% (284) | heat shock protein HtpX |
| M. leprae Br4923 | MLBr_02278 | htpX | 1e-133 | 82.23% (287) | heat shock protein HtpX |
| M. abscessus ATCC 19977 | MAB_3927c | - | 1e-123 | 79.36% (281) | protease HtpX-like protein |
| M. marinum M | MMAR_0912 | hspX | 1e-141 | 86.97% (284) | peptidase heat shock protein X, HspX |
| M. avium 104 | MAV_4580 | - | 1e-142 | 87.11% (287) | heat shock protein HtpX |
| M. thermoresistible (build 8) | TH_1766 | htpX | 1e-146 | 85.86% (297) | PROBABLE PROTEASE TRANSMEMBRANE PROTEIN HEAT SHOCK PROTEIN |
| M. ulcerans Agy99 | MUL_0665 | hspX | 1e-140 | 86.27% (284) | heat shock protein HtpX |
| M. vanbaalenii PYR-1 | Mvan_0993 | - | 1e-143 | 86.10% (295) | heat shock protein HtpX |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5252|M.gilvum_PYR-GCK MTWHP-HANRAKTFLLLAVFSGLIVAVGAMFG-RNIMFLAVLFALGMNAY
Mvan_0993|M.vanbaalenii_PYR-1 MTWHP-HANRAKTFLLLVLFSGLIVGVGALFG-RNIMFLAVLFAIGMNAY
MSMEG_1134|M.smegmatis_MC2_155 MTWNP-HANRLKTFLLLVGMSGLIVFVGSLFG-RNVMFLAVLFAVGMNAY
TH_1766|M.thermoresistible__bu MTWNP-HANRLKTFVLLVGMSALIVFIGALFQNRSILFLAVLFAVGMNVY
MMAR_0912|M.marinum_M MTWHP-HANRLKTFLLLVGMSAMIVFFGALFG-RTALILAVLFAVGMNVY
MUL_0665|M.ulcerans_Agy99 MTWHP-HANRLKTFLLLVGMSAMIVFFGALFG-RTALILAVLFAVGMNVY
Mb0578|M.bovis_AF2122/97 MTWHP-HANRLKTFLLLVGMSALIVAVGALFG-RTALMLAALFAVGMNVY
Rv0563|M.tuberculosis_H37Rv MTWHP-HANRLKTFLLLVGMSALIVAVGALFG-RTALMLAALFAVGMNVY
MLBr_02278|M.leprae_Br4923 MTWHP-QANRLKTFVLLVGMSTLIVVVGAIFG-RTALFFATLVAVGINVY
MAV_4580|M.avium_104 MTWHP-HANRFKTFALLVGMSALIVFVGSLFG-RTAMFFAVLFAIGMNVY
MAB_3927c|M.abscessus_ATCC_199 MPAVPSHANGLKTVLLLGGMSAMIVFIGSLFHSKSILLLAIVFAVGMNAY
*. * :** **. ** :* :** .*::* :. :::* :.*:*:*.*
Mflv_5252|M.gilvum_PYR-GCK VYFNSDKLALRAMHAQPVNEMQAPVMYKIVRELATTARQPMPRLYISDTA
Mvan_0993|M.vanbaalenii_PYR-1 VYFNSDKLALRAMHAQPVNEMQAPVMYKIVRELATTARQPMPRLYISDTA
MSMEG_1134|M.smegmatis_MC2_155 VYFNSDKLALRAMHAQPITEVQAPEIYRIVRELATTAHQPMPRLYISDTA
TH_1766|M.thermoresistible__bu VYFNSDKLALRAMHAQPVTELQAPVMYRIVRELANTAHQPMPRLYISDTA
MMAR_0912|M.marinum_M VYFNSDKLALRAMHAQPVSELQAPAMYRIVRELATSAHQPMPRLYISDTA
MUL_0665|M.ulcerans_Agy99 VYFNSDKLALRAMHAQPVSELQAPAMYRIVRELAASAHQPMPRLYISDTA
Mb0578|M.bovis_AF2122/97 VYFNSDKLALRAMHAQPVSELQAPAMYRIVRELATSAHQPMPRLYISDTA
Rv0563|M.tuberculosis_H37Rv VYFNSDKLALRAMHAQPVSELQAPAMYRIVRELATSAHQPMPRLYISDTA
MLBr_02278|M.leprae_Br4923 TYYNSDKLALRAMHAQPVSEVQAPVMYRIVRELATGAHQPMPRLYISDTN
MAV_4580|M.avium_104 TYYNSDKLALRAMHAQPVSELQAPAMYRIVRELATAAHQPMPRLYISDTN
MAB_3927c|M.abscessus_ATCC_199 VYFKSDTLALRAMHAQPVTELQQPAMYRIVRELATVARQPMPRLYISDTN
.*::**.**********:.*:* * :*:****** *:***********
Mflv_5252|M.gilvum_PYR-GCK APNAFATGRNPRNSAVCCTTGILQMLNERELRAVLGHELSHVYNRDILIS
Mvan_0993|M.vanbaalenii_PYR-1 APNAFATGRNPRNAAVCCTTGILQMLNERELRAVLGHELSHVYNRDILIS
MSMEG_1134|M.smegmatis_MC2_155 NPNAFATGRNPRNAAVCCTTGILQLLNERELRAVLGHELSHVYNRDILIS
TH_1766|M.thermoresistible__bu NPNAFATGRNPRNAAVCCTTGLLQILNERELRAVLGHELSHVYNRDILIS
MMAR_0912|M.marinum_M APNAFATGRNPRNAAVCCTTGILALLNERELRAVLGHELSHVYNRDILIS
MUL_0665|M.ulcerans_Agy99 APNAFATGRNPRNAAVCCTTGILALLNERELRAVLGHELSHVYNRDILIS
Mb0578|M.bovis_AF2122/97 APNAFATGRNPRNAAVCCTTGILRILNERELRAVLGHELSHVYNRDILIS
Rv0563|M.tuberculosis_H37Rv APNAFATGRNPRNAAVCCTTGILRILNERELRAVLGHELSHVYNRDILIS
MLBr_02278|M.leprae_Br4923 APNAFATGRNPRNAAVCCTTGILEILNERELRAVLGHELSHVYNRDILIS
MAV_4580|M.avium_104 APNAFATGRNPRNAAVCCTTGILGILNERELRAVLGHELSHVYNRDILIS
MAB_3927c|M.abscessus_ATCC_199 APNAFATGRNPRNAAVCCTTGILDLLSERELRAVLGHELSHVYNRDILIS
************:*******:* :*.***********************
Mflv_5252|M.gilvum_PYR-GCK CVAGAMASVITALANLAFFASMFGGNRDGGTNPFAILLVSLLGPIAATVI
Mvan_0993|M.vanbaalenii_PYR-1 CVAGAMASVITALANLAFFASMFGGNRDGGTNPLAILLVSLLGPIAATVI
MSMEG_1134|M.smegmatis_MC2_155 CVAGAMASVITALANMAMFAGMFGGNREGG-NPLALLLVSFLGPIAATVV
TH_1766|M.thermoresistible__bu CVAGALAAIVTALANIAMYASMFGGNRQGGPSPFALLLVSFLGPIAATVI
MMAR_0912|M.marinum_M CIAGALASVITALANMAMWAGMFG-GNRDGQNPFALLLVSLLGPIAATVV
MUL_0665|M.ulcerans_Agy99 CIAGALASVITALANMAMWAGMFG-GKRDGQNPFALLLVSLLGPIAATVV
Mb0578|M.bovis_AF2122/97 CVAGALAAVITALANMAMWAGMFG-GNRDNANPFALLLVALLGPIAATVI
Rv0563|M.tuberculosis_H37Rv CVAGALAAVITALANMAMWAGMFG-GNRDNANPFALLLVALLGPIAATVI
MLBr_02278|M.leprae_Br4923 CVAGALAGVITALANMAMWAGTFG-TTRDEENPFALLLVSLLGPIAATVV
MAV_4580|M.avium_104 CIAGAMASVITALANMAMFAGMFGGNDRDGENPFALLLVSLLGPIAATVV
MAB_3927c|M.abscessus_ATCC_199 SVAGALAAVISGLANMAMFLNFFGGGDENRPNPFALFLVSMLGPIAATVV
.:***:*.:::.***:*:: . ** . .*:*::**::********:
Mflv_5252|M.gilvum_PYR-GCK RLAVSRSREYQADQSGAELTGDPLALASALRKISSGVERAPLPPEPQLAD
Mvan_0993|M.vanbaalenii_PYR-1 RLAVSRSREYQADQSGAELTGDPLALASALRKISAGVERAPLPPEPQLAD
MSMEG_1134|M.smegmatis_MC2_155 KLAVSRSREYQADQSGAELTGDPLALASALRKISGGVEAAPLPPQPQLAD
TH_1766|M.thermoresistible__bu RMAVSRSREYQADQSGAELTGDPLALASALRKISGGVQAAPLPPEPQLAD
MMAR_0912|M.marinum_M RMAVSRSREYQADESGAVLTGDPLALASALRKISGGVQLAPLPPEPQLAS
MUL_0665|M.ulcerans_Agy99 RMAVSRSREYQADESGAVLTGDPLALASALRKISGGVQLAPLPPEPQLAS
Mb0578|M.bovis_AF2122/97 RMAVSRSREYQADESGAVLTGDPLALASALRKISGGVQAAPLPPEPQLAS
Rv0563|M.tuberculosis_H37Rv RMAVSRSREYQADESGAVLTGDPLALASALRKISGGVQAAPLPPEPQLAS
MLBr_02278|M.leprae_Br4923 RLAVSRSREYQADESGAMLTGDPLALASALRKISSGVQAAPLPPEPQLAS
MAV_4580|M.avium_104 RLAVSRSREYQADESGAVLTGDPLALASALRKISGGVQAAPLPPEPQLAS
MAB_3927c|M.abscessus_ATCC_199 KMAVSRSREYQADQSGAELTGDPLALASALRKISGGVQAAPLPPEPQLAS
::***********:*** ****************.**: *****:****.
Mflv_5252|M.gilvum_PYR-GCK QAHLMIANPFRAGEKIGKLFATHPPMADRIARLEAMAG----RGPGQY-
Mvan_0993|M.vanbaalenii_PYR-1 QAHLMIANPFRSGEKIGKLFATHPPIADRIARLEAMAGPDTYRHPGLY-
MSMEG_1134|M.smegmatis_MC2_155 QAHLMIASPFRAGERIGKLFSTHPPIADRIRRLEDMAGRGGSRPDSYY-
TH_1766|M.thermoresistible__bu QAHLMIASPFRAGEKIGKLFSTHPPIEDRIARLEAMAG----RGPGHYY
MMAR_0912|M.marinum_M QAHLMIANPFRAGERIGSLFSTHPPIEDRIRRLEQMARG----------
MUL_0665|M.ulcerans_Agy99 QAHLMIANPFRAGERIGSLFSTHPPIEDRIRRLEQMARG----------
Mb0578|M.bovis_AF2122/97 QAHLMIANPFRAGERIGSLFSTHPPIEDRIRRLEAMARG----------
Rv0563|M.tuberculosis_H37Rv QAHLMIANPFRAGERIGSLFSTHPPIEDRIRRLEAMARG----------
MLBr_02278|M.leprae_Br4923 QAHLMIANPFRVGDRIGSLFSTHPPIEDRIRRLETMVAGR---------
MAV_4580|M.avium_104 QAHLMIANPFRAGERIGSLFSTHPPIEDRIRRLESMAG-R---------
MAB_3927c|M.abscessus_ATCC_199 QSHLMIANPFRASDRVASLFSTHPPMADRIARLENMARF----------
*:*****.*** .:::..**:****: *** *** *.