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M. smegmatis MC2 155 MSMEG_0809 (-)

annotation: isoprenylcysteine carboxyl methyltransferase
coordinates: 894762 - 895265
length: 167

MKAFTALVAAVAAERLAELVVSKRNLEWSKTHGGKEFGAGHYPVMVALHTGLLAGAALEARRRRVRPALG
RPMFAVVLAAQGLRWWCIKTLGPQWNTRVIVVPGATRVLAGPYRFLPHPNYVAVVAEGVALPLVGGAWRT
ALGFTIANALLLRTRIRVENDALRSLT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0809--100% (167)isoprenylcysteine carboxyl methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1171c-1e-5264.78% (159) hypothetical protein Mb1171c
M. gilvum PYR-GCKMflv_5141-9e-6572.12% (165) isoprenylcysteine carboxyl methyltransferase
M. tuberculosis H37RvRv1139c-1e-5264.78% (159) hypothetical protein Rv1139c
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4314-2e-5061.01% (159) hypothetical protein MMAR_4314
M. avium 104MAV_1279-4e-5366.67% (159) isoprenylcysteine carboxyl methyltransferase (icmt) family
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0980-6e-5060.38% (159) hypothetical protein MUL_0980
M. vanbaalenii PYR-1Mvan_1195-3e-6068.90% (164) isoprenylcysteine carboxyl methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1171c|M.bovis_AF2122/97           ---MYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILH
Rv1139c|M.tuberculosis_H37Rv        ---MYYLLILAVVFERLAELVVAQRNARWSFAQGGKEFGRPHYVVMVILH
MMAR_4314|M.marinum_M               MVSPYYLLILAIVVERLAELVIAQRNARWSFAQGGKEFGQPHYVVMVVLH
MUL_0980|M.ulcerans_Agy99           MVSPYYLLILAIVVERLAELVIAQRNARWSFAQGGKEFGQPHYVVMVVLH
MAV_1279|M.avium_104                ---MYYLLVLAVGLERVAELLVSTRNARWSFTQGGKEFGRSHYPVMVFIH
Mflv_5141|M.gilvum_PYR-GCK          -MFAYTLLIAAVAVERLAELVVSQRNLKWSKARGGVEFGAGHYPVMVVLH
Mvan_1195|M.vanbaalenii_PYR-1       -MLAYTLLIAAVALERVAELVVSQRNLRWSRARGGVEFGATHYPLMVLLH
MSMEG_0809|M.smegmatis_MC2_155      -MKAFTALVAAVAAERLAELVVSKRNLEWSKTHGGKEFGAGHYPVMVALH
                                        :  *: *:  **:***::: ** .** ::** ***  ** :** :*

Mb1171c|M.bovis_AF2122/97           TALLLGCVVEPWALHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNT
Rv1139c|M.tuberculosis_H37Rv        TALLLGCVVEPWALHRPFIPWLGWPMLAVVVASQGLRWWCVKSLGKRWNT
MMAR_4314|M.marinum_M               SLLLVGCVIEPWALHRPFIPWLGWPMVAVLVLSQGLRWWCVTSLGRRWNT
MUL_0980|M.ulcerans_Agy99           SLLLVGCVIEPWALYRPFIPWLGWPMVAVLVLSQGLRWWCVTSLGRRWNT
MAV_1279|M.avium_104                TALLAGCLVEPWALHRPFLGWLGWPMLAVVAASQGLRWWCITTLGRRWNT
Mflv_5141|M.gilvum_PYR-GCK          TALLVGCLVE--ASHREFIPALGWTMFAVAIAAQALRWWCITTLGPQWNT
Mvan_1195|M.vanbaalenii_PYR-1       TVLLAACLVE--AAHREFIPVLGWSMFALVVAAQGLRWWCITTLGHQWNT
MSMEG_0809|M.smegmatis_MC2_155      TGLLAGAALE--ARRRRVRPALGRPMFAVVLAAQGLRWWCIKTLGPQWNT
                                    : ** .. :*  *  * .   ** .*.*:   :*.*****:.:** :***

Mb1171c|M.bovis_AF2122/97           RVIVLPHATLVRRGPYRWMRHPNYVAVVAEGFALPLVHTAWLTALVFTLA
Rv1139c|M.tuberculosis_H37Rv        RVIVLPHATLVRRGPYRWMRHPNYVAVVAEGFALPLVHTAWLTALVFTLA
MMAR_4314|M.marinum_M               RVIVLPDEPLVQKGPYRFLHHPNYVAVVAEGFALPLVHTAWVTALSFTVA
MUL_0980|M.ulcerans_Agy99           RVIVLPDEPLAQKGPYRFLHHPNYVAVVAEGFALPLVHTAWVTALSFTVA
MAV_1279|M.avium_104                RVIVLPQAPLVRDGPYRWLHHPNYVAVVAEGLALPLVHTAWLTAAVFTLA
Mflv_5141|M.gilvum_PYR-GCK          RVVVVPNAGRVTGGPYRFMSHPNYVAVVVEGIALPLVHTAWITALVFTVL
Mvan_1195|M.vanbaalenii_PYR-1       RVVVVPGAGRVTGGPYRFLSHPNYVAVVVEGIALPLVHTAWVTALAFTLL
MSMEG_0809|M.smegmatis_MC2_155      RVIVVPGATRVLAGPYRFLPHPNYVAVVAEGVALPLVGGAWRTALGFTIA
                                    **:*:*    .  ****:: ********.**.*****  ** **  **: 

Mb1171c|M.bovis_AF2122/97           NATLLTVRLRVENSVLGYI----
Rv1139c|M.tuberculosis_H37Rv        NATLLTVRLRVENSVLGYI----
MMAR_4314|M.marinum_M               NAILLTVRLRVENSVLGYS----
MUL_0980|M.ulcerans_Agy99           NAILLTVRLRVENSVLGYS----
MAV_1279|M.avium_104                NAALLRVRLRVENSALGYT----
Mflv_5141|M.gilvum_PYR-GCK          NAALLWTRISVENKALRTLTAAR
Mvan_1195|M.vanbaalenii_PYR-1       NAALLWMRISVEDKALRTLHT--
MSMEG_0809|M.smegmatis_MC2_155      NALLLRTRIRVENDALRSLT---
                                    ** **  *: **:..*