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MDQLWANRAASAEAAITERHLKKLWGLPGTQLGVVAWPPARKYTLFGTWHYWWQAHLLDCLVDAQVRDPQ PERTTRIERQLRAHRLRNNLSWVNDYYDDMAWLALAIERAGRLAGVEKPTALRKLCDQFVTAWVPEDGGG IPWRKQDQFFNAPANGPAGIFLARYDDRLRRAQQMADWIDETLIDPDTHLVFDGIKAGSLVRAQYTYCQG VVLGLEVELAVRTQDPRHAPRVRRLVAAVDKEMTTDGVIKGAGGGDGGLFNGILARYLALVATTLPGETP EDIAARDTARTIVLKSARSAWDHRQTVDGLPLFSAFWDRNAEIPTAGGKEAEFVEGAVNASSVPERDLSV QLAGWMLMEAAHSVDSVDAEDAAGDQNGAGDGEVGHDENEDEE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0740 | - | - | 100% (393) | glycosyl hydrolase family protein 76 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0372c | - | 1e-165 | 74.66% (371) | hypothetical protein Mb0372c |
| M. gilvum PYR-GCK | Mflv_0239 | - | 1e-160 | 72.68% (377) | glycoside hydrolase family protein |
| M. tuberculosis H37Rv | Rv0365c | - | 1e-165 | 74.66% (371) | hypothetical protein Rv0365c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4257c | - | 1e-142 | 67.40% (365) | hypothetical protein MAB_4257c |
| M. marinum M | MMAR_0667 | - | 1e-174 | 77.51% (369) | glycosyl hydrolase |
| M. avium 104 | MAV_4787 | - | 1e-173 | 76.47% (374) | hypothetical protein MAV_4787 |
| M. thermoresistible (build 8) | TH_0178 | - | 1e-166 | 72.29% (397) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0105 | - | 1e-173 | 77.51% (369) | glycosyl hydrolase |
| M. vanbaalenii PYR-1 | Mvan_0666 | - | 1e-171 | 77.84% (370) | glycoside hydrolase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0372c|M.bovis_AF2122/97 --------MN--LANRAASAETAVTQRHLRRLWALPGTQLAVVAWPSTRR
Rv0365c|M.tuberculosis_H37Rv --------MN--LANRAASAETAVTQRHLRRLWALPGTQLAVVAWPSTRR
MMAR_0667|M.marinum_M --------MDQLWANRAASSEAAITGRHFKRLWGLPGTQLGVVSWPSERK
MUL_0105|M.ulcerans_Agy99 MSGAGSGAMDQLSANRAASSEAAITGRHFKRLWGLPGTQLGVVSWPSERK
MAV_4787|M.avium_104 --------MDQLWANRAASCEAAVTQRHLRRLWGLPATQLGVVAWPPTRR
MSMEG_0740|M.smegmatis_MC2_155 --------MDQLWANRAASAEAAITERHLKKLWGLPGTQLGVVAWPPARK
Mflv_0239|M.gilvum_PYR-GCK --------MDQMWANRAASAEAAITTRHLRRVWGLPGTQLGVVAWPAATG
Mvan_0666|M.vanbaalenii_PYR-1 --------MDQMWANRAASAEAAISARHLRRLWGLPRTQLGVVAWPADGR
TH_0178|M.thermoresistible__bu --------MEQLWANRAASAEAAITQRHLRRLWGLPGTQLGVVAWPATGR
MAB_4257c|M.abscessus_ATCC_199 --------MDVLWANRASSAEAAITARHLSPLWHLPGMQLGVVTWPPAPG
*: ****:*.*:*:: **: :* ** **.**:**.
Mb0372c|M.bovis_AF2122/97 DRLFGSWHYWWQAHLLDCLVDAQLRDPQPQRRARINRQVRSHRVRNNFSW
Rv0365c|M.tuberculosis_H37Rv DRLFGSWHYWWQAHLLDCLVDAQLRDPQPQRRARINRQVRSHRVRNNFSW
MMAR_0667|M.marinum_M DRMFGTWHYWWQAHLLDCLIDAELRDPQAERRSRINRQVRSHRLRNNFSW
MUL_0105|M.ulcerans_Agy99 DRMFGTWHYWWQAHLLDCLIDAELRDPQAERRSRINRQVRSHRLRNNFSW
MAV_4787|M.avium_104 DRWFGTWHYWWQAHLLDCLVDAQQRDPQPQRRARINRQVRSHRLRNNLSW
MSMEG_0740|M.smegmatis_MC2_155 YTLFGTWHYWWQAHLLDCLVDAQVRDPQPERTTRIERQLRAHRLRNNLSW
Mflv_0239|M.gilvum_PYR-GCK HRRFGTWHYWWQAHLLDNLVDAQLRDPAPERLTRINRQIRGQRIRNIGKW
Mvan_0666|M.vanbaalenii_PYR-1 HRRFGTWHYWWQAHLLDNLVDAQVRDPRPERLSVITKQIRGLRLRNIGRW
TH_0178|M.thermoresistible__bu ERRFAIWHYWWQAHLLDCLVDAQLRDPQPDRLKRINRQIRGHRLRNMGRW
MAB_4257c|M.abscessus_ATCC_199 ATWFKNWHYWWQAHLQDCLIDAQLRDPRPDRLKYIADMQRAHRFRNVFMW
* ********* * *:**: *** .:* * *. *.** *
Mb0372c|M.bovis_AF2122/97 LNSYYDDMAWLALALERADRVAGVRRRRALPKLTNQFVEAWVPEDGGGIP
Rv0365c|M.tuberculosis_H37Rv LNSYYDDMAWLALALERADRVAGVRRRRALPKLTNQFVEAWVPEDGGGIP
MMAR_0667|M.marinum_M TNSYYDDMAWLALALERAARIAGVQRRRALPKLADQFVKAWVPEDGGGIP
MUL_0105|M.ulcerans_Agy99 TNSYYDDMAWLALALERAARIAGVQRRRALPKLADQFVKAWVPEDGGGIP
MAV_4787|M.avium_104 TNSYYDDMAWLALALERAARIAGVHRRKALPKLANQFLRAWVPEDGGGIP
MSMEG_0740|M.smegmatis_MC2_155 VNDYYDDMAWLALAIERAGRLAGVEKPTALRKLCDQFVTAWVPEDGGGIP
Mflv_0239|M.gilvum_PYR-GCK TNSYYDDMAWLALALERAQRLTGVGRPKALDTLAEQFLTAWVPEDGGGIP
Mvan_0666|M.vanbaalenii_PYR-1 TNDYYDDMAWLALALERAGRLTGVTRPRALAKLADQFVTAWVPEDGGGIP
TH_0178|M.thermoresistible__bu TNDYYDDMAWLALALERSGRLTGVGRPKALDTLAGQLFSAWVPEDGGGIP
MAB_4257c|M.abscessus_ATCC_199 TNQYYDDMAWLALAMQRASELLGLERPRALNRLRQQFLDAWMPQYGGGIP
*.***********::*: .: *: : ** * *:. **:*: *****
Mb0372c|M.bovis_AF2122/97 WRKQDQFFNAPANGPAGLFLARYPDQYGKRLKRAEQMADWIDRTLIDPET
Rv0365c|M.tuberculosis_H37Rv WRKQDQFFNAPANGPAGLFLARYPDQYGKRLKRAEQMADWIDRTLIDPET
MMAR_0667|M.marinum_M WRKQDQFFNAPANGPAGIFLARYDD----RLARAEQMGDWIDRTLIDPET
MUL_0105|M.ulcerans_Agy99 WRKQDQFFNAPANGPAGIFLARYDD----RLARAEQMGDWIDRTLIDPET
MAV_4787|M.avium_104 WRKSDQFFNAPANGPAGIFLARYGD----HLKRAEQMANWIDETLIDPET
MSMEG_0740|M.smegmatis_MC2_155 WRKQDQFFNAPANGPAGIFLARYDD----RLRRAQQMADWIDETLIDPDT
Mflv_0239|M.gilvum_PYR-GCK WRKQDQFFNAPANGPAAIFLARHLAAQGESLRRAQQMADWIDETLLDPQT
Mvan_0666|M.vanbaalenii_PYR-1 WRKQDQFFNTPANGPAAIFLAR----YDDRLRRAQQMADWIDDTLIDPET
TH_0178|M.thermoresistible__bu WRRQDQFFNAPANGPAAIFLAR-----YDRLRRAEQMADWLHATLIDPET
MAB_4257c|M.abscessus_ATCC_199 WRKQDRFFNAPANGPAAIVLARTG-----RVWRAEVMSDWIDKTLVDPDS
**:.*:***:******.:.*** : **: *.:*:. **:**::
Mb0372c|M.bovis_AF2122/97 HLVFDGIKA-GSLVRAQYTYCQGVVLGLETELAVRTGPAARARHCARVHR
Rv0365c|M.tuberculosis_H37Rv HLVFDGIKA-GSLVRAQYTYCQGVVLGLETELAVRTGPAARARHCARVHR
MMAR_0667|M.marinum_M HLVFDGIKG-GSLVRAQYTYCQGVVLGLETELAARTG---NDRHAPRVHR
MUL_0105|M.ulcerans_Agy99 HLVFDGIKG-GSLVRAQYTYCQGVVLGLETELAARTG---NDRHAPRVHR
MAV_4787|M.avium_104 HLVFDGIKA-GSLVRAQYTYCQGVVLGLETELAARTDGPARQRHAARVRR
MSMEG_0740|M.smegmatis_MC2_155 HLVFDGIKA-GSLVRAQYTYCQGVVLGLEVELAVRTQ---DPRHAPRVRR
Mflv_0239|M.gilvum_PYR-GCK HLIFDGIKG-GSLVRAQYTYCQGVVLGVETELAARTS---DSRHAERVHR
Mvan_0666|M.vanbaalenii_PYR-1 HLVFDGIKA-GSLVRAQYTYCQGVVLGLETELAVRTE---DARHPERVHR
TH_0178|M.thermoresistible__bu HLVFDGIKA-GSLVRAQYTYCQGVVLGLEAELAVRTG---NPVHARRVYR
MAB_4257c|M.abscessus_ATCC_199 HLVIDGIQEDGTLERATYTYCQGVVLGLETELAVRTA---EPRHAQRVHR
**::***: *:* ** **********:*.***.** * ** *
Mb0372c|M.bovis_AF2122/97 LVAAVNEHMAPLGVLRGAGGGDGGLFAGITARYLALVATTLPGDSADDAA
Rv0365c|M.tuberculosis_H37Rv LVAAVNEHMAPLGVLRGAGGGDGGLFAGITARYLALVATTLPGDSADDAA
MMAR_0667|M.marinum_M LVAAVAEHMASAGVLKGAGGGDGGLFAGITARYLALVTTTLPGDSADDAQ
MUL_0105|M.ulcerans_Agy99 LVAAVAEHMASAGVLKGAGGGDGGLFAGITARYLALVATTLPGDSADDAQ
MAV_4787|M.avium_104 LVAAVAEHMAPAGVLAGAGGGDGGLFAGVTARYLALVATTLPGSAAEDVA
MSMEG_0740|M.smegmatis_MC2_155 LVAAVDKEMTTDGVIKGAGGGDGGLFNGILARYLALVATTLPGETPEDIA
Mflv_0239|M.gilvum_PYR-GCK LVAAVAEHMAPGGVINGAGGGDGGLFNGILARYLALVATALPGTSPADEQ
Mvan_0666|M.vanbaalenii_PYR-1 LVAAVAEHMAPAGVIKGAGGGDGGLFNGILARYLALVATALPGGSPADDK
TH_0178|M.thermoresistible__bu LVAAVRDHMAPDGVIKGAGGGDGGLFNAILARYLALVAQILPDGPGADAE
MAB_4257c|M.abscessus_ATCC_199 LVRAVRDLMTEDGVIRGSGGGDGGLFNGILARYLALVVTLLPQNSPQDAD
** ** . *: **: *:******** .: *******. ** . *
Mb0372c|M.bovis_AF2122/97 A----RDTARAIVLASAQSAWDYRQT---VDGLPVFGAFWDREAELPTAG
Rv0365c|M.tuberculosis_H37Rv A----RDTARAIVLASAQSAWDYRQT---VDGLPVFGAFWDREAELPTAG
MMAR_0667|M.marinum_M A----RDTARAIVLASAKSAWDCRQT---ADGLPVFGAFWDRDAELPTAE
MUL_0105|M.ulcerans_Agy99 A----RDTARAIVLASAKSAWDCRQT---ADGLPVFGAFWDRDAELPTAE
MAV_4787|M.avium_104 A----RDTARRIVLASAKSAWDYRQT---LDGLPVFGPFWDRDAQLPTAG
MSMEG_0740|M.smegmatis_MC2_155 A----RDTARTIVLKSARSAWDHRQT---VDGLPLFSAFWDRNAEIPTAG
Mflv_0239|M.gilvum_PYR-GCK A----RRTATELVLASGRAAWDNRQTGKDTEDLPLFGAFWDRPAQVPTAG
Mvan_0666|M.vanbaalenii_PYR-1 A----RETATELVLTSARTAWDNRQT---VEGLPLFAAFWDRPAELPTAG
TH_0178|M.thermoresistible__bu ASRTTRETARTLVLDSARSAWDHRQV---VDGLPLFGPFWDRAAELPRAG
MAB_4257c|M.abscessus_ATCC_199 A----RATARDILLASAEAAWANRLT---VESLPLFGADWTRTADLPTAQ
* * ** ::* *..:** * . :.**:*.. * * *::* *
Mb0372c|M.bovis_AF2122/97 GEQARSVRGAVHSSAIAERDLSVQLSGWMLMEAAHSAAAVSSLG------
Rv0365c|M.tuberculosis_H37Rv GEQARSVRGAVHSSAIAERDLSVQLSGWMLMEAAHSAAAVSSLG------
MMAR_0667|M.marinum_M GQQAQFVEGAVQGSEIAERDLSVQLSGWMLMEAAHSVAAVSSLG------
MUL_0105|M.ulcerans_Agy99 GQQAQFVEGAVQGSEIAERDLSVQLSGWMLMEAAHSVAAVSSLG------
MAV_4787|M.avium_104 GKQAEFVEGAVTASEIAERDLSVQLSGWMLMEAACNVSAESSHENRSAL-
MSMEG_0740|M.smegmatis_MC2_155 GKEAEFVEGAVNASSVPERDLSVQLAGWMLMEAAHSVDSVDAEDAAGDQN
Mflv_0239|M.gilvum_PYR-GCK TADARSVDGAVNSSEIPERDLSVQLAGWMLMEAACVVTAGDSD-------
Mvan_0666|M.vanbaalenii_PYR-1 SGDAELVDGAVNSSEIPERDLSVQLAGWMLLEAAHVVTAGDSD-------
TH_0178|M.thermoresistible__bu GREAQFVEGAVNASEIPERDLSVQLSGWMLMEAAHALTDETSAETSTDET
MAB_4257c|M.abscessus_ATCC_199 SAASQFVAGAVNPSKVPERDLSVQLSGWMLLEAAHVVA------------
:. * *** * :.********:****:***
Mb0372c|M.bovis_AF2122/97 ----------------
Rv0365c|M.tuberculosis_H37Rv ----------------
MMAR_0667|M.marinum_M ----------------
MUL_0105|M.ulcerans_Agy99 ----------------
MAV_4787|M.avium_104 ----------------
MSMEG_0740|M.smegmatis_MC2_155 GAGDGEVGHDENEDEE
Mflv_0239|M.gilvum_PYR-GCK ----------------
Mvan_0666|M.vanbaalenii_PYR-1 ----------------
TH_0178|M.thermoresistible__bu ADEADEEENPA-----
MAB_4257c|M.abscessus_ATCC_199 ----------------