For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RIALFATCLADALFPPAAIATVQLLERLGHEVVFPSQQTCCGQMHINTGYFKEAVAVVRNHVESFESARC DAVVAPSGSCVGSVRHQHAMVARRAGDEDLAVRAEKIAERTYELSEFLVDVLGVDDVGAYYPHRVTYHPT CHSLRMLGVGDKPLRLLRNVRGLTLVELPAAESCCGFGGTFALKNSDTSTAMLADKMTHILETGAEVCSA GDSSCLMHIGGGLSRLRSGVRTVHLAEILAGAEA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0595 | - | - | 100% (245) | glycolate oxidase |
| M. smegmatis MC2 155 | MSMEG_2492 | - | 8e-10 | 24.60% (248) | D-lactate dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3704 | - | 4e-88 | 66.12% (245) | hypothetical protein Mflv_3704 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4817 | - | 6e-05 | 26.72% (116) | ferredoxin, 4Fe-4S |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2709 | - | 2e-85 | 65.43% (243) | hypothetical protein Mvan_2709 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 MTTQMLIRLVVGMGMTLIVAALAARRVLWLFKLITSGKPAPGHTDDPGKR
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 VWAEVSEVFGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLFQDNF
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 HIPIIGRWDALGFLQDFFATAVFLGIATFAVIRSMRSPREIGRSSRFYGS
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 HTGGAWLVLFMIFNVIWTYVLVRGSAVNNGTLPYGKGAFLSQLFGAILRP
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 LGQPANEYIETAALLAHIAVMLAFLIIVLHSKHMHIFTAPINVIFKRLPN
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 GLGPLLPIEYDGKPIDFENPPDDAVFGRGKVEDFSWKAMLDFATCTECGR
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 CQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGDKQSPLESTPEGGV
Mflv_3704|M.gilvum_PYR-GCK ------------------------------------------------MN
Mvan_2709|M.vanbaalenii_PYR-1 ------------------------------------------------MN
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 GEELSGEKHAEAHHVPESGFGRVMGSGPEQATRPLVGTEEQGGVIDPDVL
Mflv_3704|M.gilvum_PYR-GCK MRVALFATCYNDLMWPETPKAVVRLLRR--LGCEVEFPAEQTCCGQMFTN
Mvan_2709|M.vanbaalenii_PYR-1 TRVALFATCYNDLMWPETPKAVVRLLRR--LGCHVEFPAAQTCCGQMFTN
MSMEG_0595|M.smegmatis_MC2_155 MRIALFATCLADALFPPAAIATVQLLER--LGHEVVFPSQQTCCGQMHIN
MAV_4817|M.avium_104 WSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEFPSELSVLFKNLET
. .:* : : :.* : . **: : : .
Mflv_3704|M.gilvum_PYR-GCK TG---------------YAEEAIPAVRNFIATFAG--YDAVVAPSGS---
Mvan_2709|M.vanbaalenii_PYR-1 TG---------------YADEAIPAVRSFVAAFAG--YDAVVAPSGS---
MSMEG_0595|M.smegmatis_MC2_155 TG---------------YFKEAVAVVRNHVESFESARCDAVVAPSGS---
MAV_4817|M.avium_104 KANPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCAGAYDD
.. . :.. . : :* . *. :*:
Mflv_3704|M.gilvum_PYR-GCK ---------------------CVGSVRHQHRDIAARAGC-----------
Mvan_2709|M.vanbaalenii_PYR-1 ---------------------CVGSVRHQHRDIAARARD-----------
MSMEG_0595|M.smegmatis_MC2_155 ---------------------CVGSVRHQHAMVARRAGD-----------
MAV_4817|M.avium_104 KAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRSGNEFLFQQLAAQA
:*: . : * *:
Mflv_3704|M.gilvum_PYR-GCK ----RAMQNEVDTLAPNVYELSEFLVDVLG--VTDVGAYFP---------
Mvan_2709|M.vanbaalenii_PYR-1 ----PGLRSAVDAVAPNVYELSEFLVDVLG--VTDVGAYFP---------
MSMEG_0595|M.smegmatis_MC2_155 ----EDLAVRAEKIAERTYELSEFLVDVLG--VDDVGAYYP---------
MAV_4817|M.avium_104 VETLDGVFEGVETVDRKIVVTCPHCFNTLGREYRQLGANYTVLHHTQLLN
: .: : . . . .:.** ::** :.
Mflv_3704|M.gilvum_PYR-GCK ---------------HRVTYHPTCHSLRMLRVGDRPLALLRAVRGIDLVE
Mvan_2709|M.vanbaalenii_PYR-1 ---------------HRVTYHPTCHSLRMLRVGDRPLRLLEAVRGIDLVA
MSMEG_0595|M.smegmatis_MC2_155 ---------------HRVTYHPTCHSLRMLGVGDKPLRLLRNVRGLTLVE
MAV_4817|M.avium_104 RLIRDNKLVPVTPVSQDITYHDPCYLGRHNKVYEAPRELIG-AAGANLTE
: :*** .*: * * : * *: . * *.
Mflv_3704|M.gilvum_PYR-GCK LPGADQ---CCGFGGTFAVKNADTSVAMGADKARAVRETEAEVLVAGDNS
Mvan_2709|M.vanbaalenii_PYR-1 LPRADQ---CCGFGGTFAMKNADTSVAMGFDKARAARDTGAEVLVAGDNS
MSMEG_0595|M.smegmatis_MC2_155 LPAAES---CCGFGGTFALKNSDTSTAMLADKMTHILETGAEVCSAGDSS
MAV_4817|M.avium_104 MPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEALATGAATVATACPF
:* . *** **: : . . : :: * * . :.
Mflv_3704|M.gilvum_PYR-GCK CLAHIGGLLSRQ-----RSGVRVMHLAEVLA-AEGAS-------------
Mvan_2709|M.vanbaalenii_PYR-1 CLAHIGGLLSRQ-----RSGMRVMHLAEILASTEGDAA------------
MSMEG_0595|M.smegmatis_MC2_155 CLMHIGGGLSRL-----RSGVRTVHLAEILAGAEA---------------
MAV_4817|M.avium_104 CRVMVTDGVNDRQEEAGRSGVEVLDVAQILLGSLEYDKATLPEKGTAAKE
* : . :. ***:..:.:*::* :
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 AEKRAAQAPKATATVEAPAKETTKEPAEAAPKAEAAPAAPAAPVKGLGIA
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 GGAKRPGAKKSAPAAEAKTEAPAEAKTEAPAAPAKGLGIAAGAKRPGAKK
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 SAPAAQAPKTEAPKTEAPKTEAKTEAAGEAKTEAPAAPAAPVKGLGIAAG
Mflv_3704|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4817|M.avium_104 AKRPGAKKAAPKAEAPKAEAEAAKAEAPKPEAPKAEAESKPEPAKPSNGE
Mflv_3704|M.gilvum_PYR-GCK --------------------------
Mvan_2709|M.vanbaalenii_PYR-1 --------------------------
MSMEG_0595|M.smegmatis_MC2_155 --------------------------
MAV_4817|M.avium_104 GGSSKPSQPPVKGLGIARGARPPGKR