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M. smegmatis MC2 155 MSMEG_0378 (nthA)

annotation: nitrile hydratase, alpha subunit
coordinates: 423733 - 424353
length: 206

VSDQFAYPAEREQDSARRVAALERLLIEKGVITDQTVDKVLGYFESEMTPLNGKKIVVKAWTDPDFAARV
VTDTPAALAELDLPEGMAGAEGEHIQAVANAPGIHNLVICTLCSCFPWPVLGLPPYWYKDPVFRARAARE
PRTVLAEVGVDLPDDTEIRVWDSSGHSRWFVIPERPAGTDDLTDEQLMDLVTTESMIGVALAGRPA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0378nthA-100% (206)nitrile hydratase, alpha subunit
M. smegmatis MC2 155MSMEG_6267-5e-3539.25% (186) thiocyanate hydrolase gamma subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_1011-1e-11092.16% (204) nitrile hydratase, alpha subunit
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5825-1e-10788.83% (206) nitrile hydratase, alpha subunit

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_0378|M.smegmatis_MC2_155      MSDQFAYPAEREQDSARRVAALERLLIEKGVITDQTVDKVLGYFESEMTP
Mflv_1011|M.gilvum_PYR-GCK          MTDQFAYPSEREQLSADRVAALERLLIEKGVITGQTVDKVLSYFESEMTP
Mvan_5825|M.vanbaalenii_PYR-1       MTDQFAYPADREKSSADRVAALEHLLIEKGVITAATVEKVLSYFESEMTP
                                    *:******::**: ** ******:*********  **:***.********

MSMEG_0378|M.smegmatis_MC2_155      LNGKKIVVKAWTDPDFAARVVTDTPAALAELDLPEGMAGAEGEHIQAVAN
Mflv_1011|M.gilvum_PYR-GCK          LNGKKIVVKAWTDPDFAARVVVDTPAAIAELDLPEGMAGAEGEHLQAVAN
Mvan_5825|M.vanbaalenii_PYR-1       LNGKKIVVKAWTDPDFAARVVDDTPAALAELDLPEGMAGAEGEHLQAVAN
                                    ********************* *****:****************:*****

MSMEG_0378|M.smegmatis_MC2_155      APGIHNLVICTLCSCFPWPVLGLPPYWYKDPVFRARAAREPRTVLAEVGV
Mflv_1011|M.gilvum_PYR-GCK          EPGVHNLVICTLCSCFPWPVLGLPPYWYKDPVFRARAAREPRTVLAEVGV
Mvan_5825|M.vanbaalenii_PYR-1       VPGVHNVVICTLCSCFPWPVLGLPPYWYKDPVFRARAAREPRTVLAEVGV
                                     **:**:*******************************************

MSMEG_0378|M.smegmatis_MC2_155      DLPDDTEIRVWDSSGHSRWFVIPERPAGTDDLTDEQLMDLVTTESMIGVA
Mflv_1011|M.gilvum_PYR-GCK          DLPDDTEIKVWDSSGHSRWFVIPERPAGTEEFTDEQLMDLVTTESMMGVA
Mvan_5825|M.vanbaalenii_PYR-1       ALPEDTEIKVWDSSGHSRWFVIPERPSGTEDLTDAELMDLVTTESMIGVA
                                     **:****:*****************:**:::** :**********:***

MSMEG_0378|M.smegmatis_MC2_155      LAGRPA
Mflv_1011|M.gilvum_PYR-GCK          LAGRTS
Mvan_5825|M.vanbaalenii_PYR-1       LAGQPA
                                    ***:.: