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VEGRQMFAAELKRFAGCVGDGNRDPRLAKISARVCAPVGVSVHGRRGVGVTTVAEALGANGVAVRDDGPG ELAVLVTVEVLKPEDLTLADALRARGADVLVVLNKADLVGRAPDGSLAAAHHRAQQLRERTGLPVVPMVG LLARATLSPHLVEALRLLATTPADLTSTEAFLADPHPVAQATRTELLTTLDRFGIVHACRELSRDPNADA AVLSAALRRLGETDRVLAALDALAAPRRYRRIERALTELQAVGGESVGRFLAADTTVVAVMDAALEVMRA AGVVVPSRAACGRDAHLRRARFWWRYCRGPVGALHGRCAAAIARGSLRLAGLDTEEAARR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0253 | - | - | 100% (340) | hypothetical protein MSMEG_0253 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0215 | - | 9e-41 | 38.59% (355) | hypothetical protein Mb0215 |
| M. gilvum PYR-GCK | Mflv_0453 | - | 1e-59 | 46.79% (312) | hypothetical protein Mflv_0453 |
| M. tuberculosis H37Rv | Rv0209 | - | 3e-40 | 38.31% (355) | hypothetical protein Rv0209 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4505c | - | 1e-37 | 33.99% (353) | hypothetical protein MAB_4505c |
| M. marinum M | MMAR_0449 | - | 2e-33 | 36.44% (354) | hypothetical protein MMAR_0449 |
| M. avium 104 | MAV_4965 | - | 2e-51 | 43.39% (348) | hypothetical protein MAV_4965 |
| M. thermoresistible (build 8) | TH_2528 | - | 1e-22 | 45.16% (155) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1099 | - | 3e-32 | 36.06% (355) | hypothetical protein MUL_1099 |
| M. vanbaalenii PYR-1 | Mvan_0199 | - | 8e-61 | 48.53% (307) | hypothetical protein Mvan_0199 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0453|M.gilvum_PYR-GCK ----------MPIFTEVLAQFVADR--------PALAAVDARLRAPLSVT
Mvan_0199|M.vanbaalenii_PYR-1 --------------------------------------MEKRLRAPHRVA
MSMEG_0253|M.smegmatis_MC2_155 -------MEGRQMFAAELKRFAGCVGDGNRD--PRLAKISARVCAPVGVS
Mb0215|M.bovis_AF2122/97 -----MRGQGHQIFVDELARFATSSAD------QRVVAIAQRAAEPLRVA
Rv0209|M.tuberculosis_H37Rv -----MRGQGHQIFVDELARFATSSAD------QRVVAIAQRAAEPLRVA
MAV_4965|M.avium_104 -----MRGQGHQIFVDELARFAAAEAD------PRVTAIAQRAAAPLRVV
MMAR_0449|M.marinum_M ------MQTGHQAFVDELTCLAASTAD------QRIRSIAERAARPLRVA
MUL_1099|M.ulcerans_Agy99 MGVMVVMQTGHQVFVDELTCLAASTAD------QRIRAIAEWAARPLRVA
TH_2528|M.thermoresistible__bu -----------------LIRFAERTGD------AAVPAIIDRLTAPVTVA
MAB_4505c|M.abscessus_ATCC_199 ------MTRGFEVFRATLERFATRPEIRQIHGGQRIHDVVVRAGDPLRVA
: * *
Mflv_0453|M.gilvum_PYR-GCK VQGRAGVGCRTVAGAL-------AAAGVRIARSSTAAD--------VHVV
Mvan_0199|M.vanbaalenii_PYR-1 VRGRRGVGRNAVAWAF-------TAAGVRVVTDIGSAD--------IQVV
MSMEG_0253|M.smegmatis_MC2_155 VHGRRGVGVTTVAEAL-------GANGVAVR-DDGPGE--------LAVL
Mb0215|M.bovis_AF2122/97 VRGRPGVGCRTVARAL-------QGAGSSSGMTVTPQARAADSDVDLVVY
Rv0209|M.tuberculosis_H37Rv VRGRPGVGCRTVARAL-------QGAGSSSGMTVTPQARAADSDVDLVVY
MAV_4965|M.avium_104 VRGRRGVGRRTLARAL-------DRAGRATGIAVTTDA------ADVVVH
MMAR_0449|M.marinum_M VRGRRGVGRNTLVRAL-------DGAGSAAGLAATSGG----DPADVVVY
MUL_1099|M.ulcerans_Agy99 VRGRRGVGRNTLARAL-------DGAGSAAGLAATSGG----DPADVVVY
TH_2528|M.thermoresistible__bu VRGRAGVGRRTVAGAL-------SAAG--VPVTADAAD--------VTVL
MAB_4505c|M.abscessus_ATCC_199 VRGRAGVGVTSVIGALGLTLPADEGPGHALIEVPIAGADPEPLVADVDVV
*:** *** :: *: * . : *
Mflv_0453|M.gilvum_PYR-GCK AVAETLKPEDRHLVRADGP----AVVVLTKADLAGRVHG----GPLAHAE
Mvan_0199|M.vanbaalenii_PYR-1 VTAETLKPEDRAMLRVSIP----TLVVLNKADLAGREPG----GPLAAAT
MSMEG_0253|M.smegmatis_MC2_155 VTVEVLKPEDLTLADALRARGADVLVVLNKADLVGRAPD----GSLAAAH
Mb0215|M.bovis_AF2122/97 VTVEVVKPEDREAIAATR---RPVVAVLNKADLAGPLSG---AGPIVMAQ
Rv0209|M.tuberculosis_H37Rv VTVEVVKPEDREAIAATR---RPVVAVLNKADLAGPLSG---AGPIVMAQ
MAV_4965|M.avium_104 VTAEVAKPEDTQAISTARAAGHPVLAVLSKADLVGSLSGRGGDGPIAAAR
MMAR_0449|M.marinum_M ALAEVVKPEDRAGIAVLEPTERPVLAVLTMADKT-DVFGFAGAGPMAGAL
MUL_1099|M.ulcerans_Agy99 ALAEVVKPEDRAGIAVLEPTERPVLAVLTMADKT-DVVGFAGAVPMAGAL
TH_2528|M.thermoresistible__bu VTAETLKPEDRAVLAGLDG---PALVVLNKADRTGWGGA----GPIDQAR
MAB_4505c|M.abscessus_ATCC_199 VFAEALKPEDRAVLEASIA---PKVLILNKADLTDPGAAR---GPWTAAV
. .*. **** : :*. ** . . *
Mflv_0453|M.gilvum_PYR-GCK RTATELTASTGVPVVPMVALLAGVEIDDD---LFEALRTLTTAPADMTSV
Mvan_0199|M.vanbaalenii_PYR-1 RRAAQIAAAAGVPVVPMIAHLASVELDEQ---DIAVLRTLAAIPVDMTST
MSMEG_0253|M.smegmatis_MC2_155 HRAQQLRERTGLPVVPMVGLLARATLSPH---LVEALRLLATTPADLTST
Mb0215|M.bovis_AF2122/97 ARCAQFSTLLGVPMESMIGLLAVAALDDLDDTLRAALRALAAHPDGFDAL
Rv0209|M.tuberculosis_H37Rv ARCAQFSTLLGVPMESMIGLLAVAALDDLDDTLRAVLRALAAHPDGFDAL
MAV_4965|M.avium_104 ARCADLSALIGVPIRPAIGLLAVAALDDLGDDLWAALRTLAADPA--ACL
MMAR_0449|M.marinum_M QRCELLSTLAGVPVEPISALLAVAALDDLDGRSWYALRALAAHPAAGAAL
MUL_1099|M.ulcerans_Agy99 QRCELLSTLAGVPVEPISALLAVAALDDLDERSWCALRALAAHPAAGAAL
TH_2528|M.thermoresistible__bu RRAGELQTLTGVPTVPLVGLLAAVRLDAG---LTTALQVLARETSDIRXX
MAB_4505c|M.abscessus_ATCC_199 SRCAEYRAETRVPTLPLSAHVPLVSLDDG---MVEALKLMVENPADTSSV
. :* . . :. . :. .*: :. .
Mflv_0453|M.gilvum_PYR-GCK D----AFVAGDHAVPASVRRALVARLDRFGIAHAVLAVADG---ASRAEV
Mvan_0199|M.vanbaalenii_PYR-1 D----AFVAADHEVPAAVRERLLARLDRFGLAHAVLACADG---ATAETL
MSMEG_0253|M.smegmatis_MC2_155 E----AFLADPHPVAQATRTELLTTLDRFGIVHACRELSRDP-NADAAVL
Mb0215|M.bovis_AF2122/97 DRAVAGFLAAALPVPTEVRLRLLDTLDLFGIALGMAAFRPGRPSRTPAQL
Rv0209|M.tuberculosis_H37Rv DRAVAGFLAAALPVPTEVRLRLLDTLDLFGIALGMAAFRPGRPSRTPAQL
MAV_4965|M.avium_104 DGSITGFLDAGVDVPAAARERLLDTLDLFGTALAIAAIRRG---AGPAQL
MMAR_0449|M.marinum_M DGSHAGFLSADLGVPTGQRLRLLESLDLFGVAIAIEALRRG---AARTQV
MUL_1099|M.ulcerans_Agy99 DGSHAGFLSADLGVPTGQRLRLLESLDLFGVAIAIEALRRG---AARTQV
TH_2528|M.thermoresistible__bu X------------TATATAPRLRS-----GPIRPIRPCGRS---GRRSKR
MAB_4505c|M.abscessus_ATCC_199 D----AFVTCTHDVPVAMRQRILHELDLYPMGCAIGALRQVP-SLAAPGL
.. :
Mflv_0453|M.gilvum_PYR-GCK ASSLHALSGADQVLDVLAGTAAEVGYRRVRSALDELTRLAVETGD--DGL
Mvan_0199|M.vanbaalenii_PYR-1 TGALRALSGADRVLECVRAAAAEVRYRRVCAAVDELHRLAAETRD--DGL
MSMEG_0253|M.smegmatis_MC2_155 SAALRRLGETDRVLAALDALAAPRRYRRIERALTELQAVGGES------V
Mb0215|M.bovis_AF2122/97 RTLLRRVSGVDAVIDKVTAAGSEVRYRRLLDAVAELEALAAQAKEIGGPI
Rv0209|M.tuberculosis_H37Rv RTLLRRVSGVDAVIDKVTAAGSEVRYRRLLDAVAELEALAAQAKEIGGPI
MAV_4965|M.avium_104 RTMLRRISGVDAVLAEIGALGAEVRYRRVLGAVAELEALAVGGAALGERI
MMAR_0449|M.marinum_M RALLRKISGIDAVVANAVAAGAGVRYGRVLEAVAALEVLAVAD----EQV
MUL_1099|M.ulcerans_Agy99 RALLRKISGIDAVVANAVAAGAGVRYGRVLEAVAALEVLAVAD----EQV
TH_2528|M.thermoresistible__bu RCSIR---------------------------------------------
MAB_4505c|M.abscessus_ATCC_199 TSLLRDLSGIDAVVSAIREAIAQGWYRRMRVVLAELRKIGVTGVLP-MQI
::
Mflv_0453|M.gilvum_PYR-GCK WSFLTGDALVIAAMAAAVDLMQAAGLRVD----PRDDA--DAHLGRALRW
Mvan_0199|M.vanbaalenii_PYR-1 AAFLASDEVVVAVMAAAVDAMEAAGLRVD----RWDDR--EAHERRAVRW
MSMEG_0253|M.smegmatis_MC2_155 GRFLAADTTVVAVMDAALEVMRAAGVVVP----SRAACGRDAHLRRARFW
Mb0215|M.bovis_AF2122/97 GEFLRDDDTVLARMAAAVDVALAVGLDVG----PLDDP--AAHLPRAVRW
Rv0209|M.tuberculosis_H37Rv GEFLRDDDTVLARMAAAVDVALAVGLDVG----PLDDP--AAHLPRAVRW
MAV_4965|M.avium_104 SGFLSRDDAVVARMAAALDMAGDMAGEVAGE-AAPGDP--SGHLARAVRW
MMAR_0449|M.marinum_M SEFLAGEAAVLARMSAALDAASAWGLDPFGAAVPPDDP--GAQLQRALRW
MUL_1099|M.ulcerans_Agy99 SEFLAGEAAVLARMSAALDAASTWGLDPFGAAVPPDDP--GAQLQRALRW
TH_2528|M.thermoresistible__bu ------------------------------------------------RW
MAB_4505c|M.abscessus_ATCC_199 DSFVNSDDVVVAAMRCAVDAATAAGIPVD----LSDHP--EDHRYRAERW
*
Mflv_0453|M.gilvum_PYR-GCK RRYAHTPMN-------ALHQQCAADIARGSLRLLGRSR------------
Mvan_0199|M.vanbaalenii_PYR-1 HRYAAGPVT-------EMHRRCAADITRGSLRLLGRRR------------
MSMEG_0253|M.smegmatis_MC2_155 WRYCRGPVG-------ALHGRCAAAIARGSLRLAGLDTE-----------
Mb0215|M.bovis_AF2122/97 HRYSLDNG--------DMHRTCGADIARGSLRLWSLAGG---------MP
Rv0209|M.tuberculosis_H37Rv HRYSLDNG--------DMHRTCGADIARGSLRLWSLAGG---------MP
MAV_4965|M.avium_104 QRYSRASGS-------DLHRACGADIARGSLRLWSQACATLPGERPVELP
MMAR_0449|M.marinum_M RRHRSQRGPAAESPDSDLRRWCGADIVRGSLRLWSRAAG----SLACAGP
MUL_1099|M.ulcerans_Agy99 RRHRSQRGPGAESPDSDLRRWCGADIVRGSLRLWSRAAG----SLACAGP
TH_2528|M.thermoresistible__bu P-------------------------ARCSTR------------------
MAB_4505c|M.abscessus_ATCC_199 QRFAEGPVN-------STYAALGTDIARGSLRLWRRAGGRA---------
.* * *
Mflv_0453|M.gilvum_PYR-GCK --------
Mvan_0199|M.vanbaalenii_PYR-1 --------
MSMEG_0253|M.smegmatis_MC2_155 -EAARR--
Mb0215|M.bovis_AF2122/97 LHRYRKSS
Rv0209|M.tuberculosis_H37Rv LHRYRKSS
MAV_4965|M.avium_104 VEREDPA-
MMAR_0449|M.marinum_M PEGGRPR-
MUL_1099|M.ulcerans_Agy99 PEGGRPR-
TH_2528|M.thermoresistible__bu --------
MAB_4505c|M.abscessus_ATCC_199 --------