For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_0218 (-)

annotation: 3-demethylubiquinone-9 3-methyltransferase
coordinates: 244773 - 245267
length: 164

MPVKINASIVPNLWFDREAEEAAEHYIAAFGGNGRILNKIAAHPDAPSPQDVPVVVEFELVGQRFVGING
GPQFTFNEAVSLEVRVAGQEQLDQVWAALTEGGEELPCGWLKDKYGLAWQVTPSEYYDMVTKGDEEANNR
LMTAVLSTHGKFDLAKLQAAYDNA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0218--100% (164)3-demethylubiquinone-9 3-methyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2098-8e-2337.01% (154) 3-demethylubiquinone-9 3-methyltransferase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1279-1e-3545.57% (158) 3-demethylubiquinone-9 3-methyltransferase
M. marinum MMMAR_4336-4e-2839.24% (158) hypothetical protein MMAR_4336
M. avium 104MAV_1255-2e-2740.65% (155) 3-demethylubiquinone-9 3-methyltransferase
M. thermoresistible (build 8)TH_2859-2e-2639.49% (157) PUTATIVE conserved hypothetical protein
M. ulcerans Agy99MUL_0146-6e-2737.97% (158) hypothetical protein MUL_0146
M. vanbaalenii PYR-1Mvan_4607-2e-2639.61% (154) 3-demethylubiquinone-9 3-methyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4336|M.marinum_M               ---------MP-----AITPSLWFDHNLAEAAQFYTSVFP-NSQIEGFNR
MUL_0146|M.ulcerans_Agy99           ---------MP-----AITPSLWFDHNLAEAAQFYTSVFP-NSQIEGFNR
MAV_1255|M.avium_104                ---------MP-----SITPSLWFDDNLEEAATFYTAVFP-NSHIEGFNR
TH_2859|M.thermoresistible__bu      ---------MP-----AIAPALWFDDNLEEAARFYTSIFP-NSSIEGFER
Mflv_2098|M.gilvum_PYR-GCK          ---------MP-----AITPSLWFDDNLEDAIGFYCSIFP-NSTHDSTEY
Mvan_4607|M.vanbaalenii_PYR-1       ---------MP-----TITPSLWFDNDLEEAIAYYSSIFP-DSAIETIER
MAB_1279|M.abscessus_ATCC_1997      MVPAPVDTGMP-----TITPCLWFDTQAEEAANFYVSVFP-NSQILEVTH
MSMEG_0218|M.smegmatis_MC2_155      ---------MPVKINASIVPNLWFDREAEEAAEHYIAAFGGNGRILNKIA
                                             **     :*.* **** :  :*  .* : *  :.       

MMAR_4336|M.marinum_M               HTEAGPGEPGTVISGTFVLDGVRFIGINGGPQFPFTEAVSFTVNCKDQDE
MUL_0146|M.ulcerans_Agy99           HTEAGPGEPGTVISGTFVLDGVRFIGINGGPPFPFTEAVSFTVNCKDQDE
MAV_1255|M.avium_104                TTEAGPGEPGTVLSGSFVLDGSRFIGINGGPHFRFSEAVSFTVHCKDQDE
TH_2859|M.thermoresistible__bu      YTDAGPGTPGEVASGTFVLDGTRFVGINGGPAFSFTEAVSFMVTCADQDE
Mflv_2098|M.gilvum_PYR-GCK          YTDAGPGTPGRALSATFTLDGQKFIGINGGPLFPFTEAVSFTIGCRDQTE
Mvan_4607|M.vanbaalenii_PYR-1       YNEAGPGTPGEVVAATFTLGGQRFIGINGGPQFPFTEAVSFTVACRDQAE
MAB_1279|M.abscessus_ATCC_1997      YGPNTPMPEGTVLTVEFELDGQRYTALNAGPQFTFDEAISFQIDCASQEE
MSMEG_0218|M.smegmatis_MC2_155      AHPDAPSPQDVPVVVEFELVGQRFVGINGGPQFTFNEAVSLEVRVAGQEQ
                                         *   .      * * * :: .:*.** * * **:*: :   .* :

MMAR_4336|M.marinum_M               VDYYWDRLTQ-GGTESQCGWCKDRFGLSWQIVPDRLYELLSDPDPARAAA
MUL_0146|M.ulcerans_Agy99           VDYYWDRLTQ-GGTESQCGWCKDRFGLSWQIVPDRLHELLSDPDPARAAA
MAV_1255|M.avium_104                VDYYWDRLSD-GGEESQCGWLKDRFGLSWQIVPDRLFELIGDPDRSRAAA
TH_2859|M.thermoresistible__bu      VDYYWDRLVD-GGQESQCGWLKDRFGLSWQIVPQRLFELVNDPDPARAAA
Mflv_2098|M.gilvum_PYR-GCK          VDYYWDRLVD-GGAASQCGWLKDRYGLSWQVVPDRLTELTSDPNPAIATA
Mvan_4607|M.vanbaalenii_PYR-1       VDYYWDRLVA-GGQESQCGWLKDRYGLSWQIVPDRLTELTSDPDPARAAA
MAB_1279|M.abscessus_ATCC_1997      VDRYWAALTADGGQESQCGWLKDKFGLSWQVVSRELIDLIFHSDPVTGNA
MSMEG_0218|M.smegmatis_MC2_155      LDQVWAALTE-GGEELPCGWLKDKYGLAWQVTPSEYYDMVTKGDEEANNR
                                    :*  *  *   **    *** **::**:**:.. .  ::  . :      

MMAR_4336|M.marinum_M               ATTAMLGMH-KIVVAELEEAVNAAG---
MUL_0146|M.ulcerans_Agy99           ATTAMLGMH-KIVVAELEEALNAAG---
MAV_1255|M.avium_104                ATQAMYGMR-KIVIAELERAAASS----
TH_2859|M.thermoresistible__bu      ATRAMLGMR-KIVIAELEEAVTNPV---
Mflv_2098|M.gilvum_PYR-GCK          ATRAMLGMT-KIVVADLEEAVAGL----
Mvan_4607|M.vanbaalenii_PYR-1       ATKAMLGMR-KILIAQLEDAVQGV----
MAB_1279|M.abscessus_ATCC_1997      AMQAMMQMR-KLDVAVAREAVAKAQAGS
MSMEG_0218|M.smegmatis_MC2_155      LMTAVLSTHGKFDLAKLQAAYDNA----
                                       *:     *: :*  . *