For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_0192 (-)

annotation: transcriptional regulator, RpiR family protein
coordinates: 216912 - 217814
length: 300

MARQDATATLADIRAVRPTLAPSERRVADVVLADPARASGFSISVLAEHAETSVATVMRFCRTVGLTSYS
QLRLALAAAAARELAREGESPAPGTDISVTDTVDEIVKKIIYNEIRVLEDTGAALDIEMLNRAIDVVSGA
RRVDISGVGASAFVAQDLHQKLHRIGRIAFVWSDRHSAVTAAALLGPGDVAFAVSHSGETDDVVEFLDAA
AGCGATTIALTNSPRSALAEAADIVLTTCARETPFRSGATVSRIAQLAVVDCLFVGVAQRSFGETTTALE
KTHAAVQRHRRSPRRTSNNG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0192--100% (300)transcriptional regulator, RpiR family protein
M. smegmatis MC2 155MSMEG_5986glmS6e-0727.50% (200) glucosamine--fructose-6-phosphate aminotransferase,
M. smegmatis MC2 155MSMEG_0474-9e-0625.81% (186) glucosamine--fructose-6-phosphate aminotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0117gmhA1e-0532.61% (92) phosphoheptose isomerase
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv0113gmhA1e-0532.61% (92) phosphoheptose isomerase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0363c-2e-0537.14% (105) glutamine-fructose-6-phosphate transaminase
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2922-6e-0925.10% (247) RpiR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0117|M.bovis_AF2122/97            -----MCTARTAEEIFVETIAVKTRILNDRVLLEAARAIG----------
Rv0113|M.tuberculosis_H37Rv         -----MCTARTAEEIFVETIAVKTRILNDRVLLEAARAIG----------
MSMEG_0192|M.smegmatis_MC2_155      MARQDATATLADIRAVRPTLAPSERRVADVVLADPARASGFSISVLAEHA
Mvan_2922|M.vanbaalenii_PYR-1       -MDERSETVEARTNAALAGLSRAERRVGRALLADYPSAGLASAARLAERA
MAB_0363c|M.abscessus_ATCC_199      ---MTAGTHMADEIRQQPTVWGRLLSDGRSAIAEVAAKIVEYSPRFVLFV
                                           :  :        :           : : .              

Mb0117|M.bovis_AF2122/97            -------------------DRLIAGYRAGARVFMCGNG-------GSAAD
Rv0113|M.tuberculosis_H37Rv         -------------------DRLIAGYRAGARVFMCGNG-------GSAAD
MSMEG_0192|M.smegmatis_MC2_155      ETSVATVMRFCRTVGLTSYSQLRLALAAAAARELAREGESPA--PGTDIS
Mvan_2922|M.vanbaalenii_PYR-1       EVSPPTVLRFAQSLGYDGFTDLQVALRAELTQQSSGPLTR----LADAPR
MAB_0363c|M.abscessus_ATCC_199      ARGTSDHAALYGKYLTEIIWQLPAGLASPSTMTTYGARPDLSGVLVIGVS
                                                         *  .  :                      

Mb0117|M.bovis_AF2122/97            AQHFAAELTGHLIFDRP---------------------------------
Rv0113|M.tuberculosis_H37Rv         AQHFAAELTGHLIFDRP---------------------------------
MSMEG_0192|M.smegmatis_MC2_155      VTDTVDEIVKKIIYNEIRVLEDTGAALDIEMLNRAIDVVSGARRVDISGV
Mvan_2922|M.vanbaalenii_PYR-1       AGSQLDRLLQQARAQNARADETLARLPAPMLEAAVALMADASRPLHLHGG
MAB_0363c|M.abscessus_ATCC_199      QSGGSPDLVQTLTVARQQ------GACTVAVTNAARSPLATAAEHHIDVL
                                           :       .                                  

Mb0117|M.bovis_AF2122/97            ---PLGAEALHANSSHLTAVANDYDYDTVFARALEGSAR-PGDTLFAIST
Rv0113|M.tuberculosis_H37Rv         ---PLGAEALHANSSHLTAVANDYDYDTVFARALEGSAR-PGDTLFAIST
MSMEG_0192|M.smegmatis_MC2_155      GASAFVAQDLHQKLHRIGRIAFVWS-DRHSAVTAAALLG-PGDVAFAVSH
Mvan_2922|M.vanbaalenii_PYR-1       RFSHLLAVYLAAHLEQLRPGVRLLSDPKGKDLGTMMDLT-RRDVVVLFDY
MAB_0363c|M.abscessus_ATCC_199      AGPELAVAATKSYTAQLLALYLLLTDVAGRDNTAAALLPERGEEILHSAV
                                        : .        ::                         :  .    

Mb0117|M.bovis_AF2122/97            SGNSMSVLRAAKTARELG-----------VTVVAMTGESGGQLAEFADFL
Rv0113|M.tuberculosis_H37Rv         SGNSMSVLRAAKTARELG-----------VTVVAMTGESGGQLAEFADFL
MSMEG_0192|M.smegmatis_MC2_155      SGETDDVVEFLDAAAGCG-----------ATTIALTNSPRSALAEAADIV
Mvan_2922|M.vanbaalenii_PYR-1       HRYHRSAAELAADVHRAG-----------ATLLLITDDMACPVAPDAEVV
MAB_0363c|M.abscessus_ATCC_199      VQQLATRYRFASRLVTTGRGYSYPTAREAALKLMETSYLSAQAFSGADLL
                                            .        *           .  :  *.         *:.:

Mb0117|M.bovis_AF2122/97            INVPSRDT-------------GRIQESHIVFIHAIS--------------
Rv0113|M.tuberculosis_H37Rv         INVPSRDT-------------GRIQESHIVFIHAIS--------------
MSMEG_0192|M.smegmatis_MC2_155      LTTCARETPFR--SGATVSRIAQLAVVDCLFVGVAQRSFGETTTALEKTH
Mvan_2922|M.vanbaalenii_PYR-1       LAASSTVG------TVYQSMSAGFLLAELLIPLVMDAIG---------EP
MAB_0363c|M.abscessus_ATCC_199      HGPLAMVDHQVPVIAIVPDGVGGRAMNDVLHRLAGRGADVCCIG-SADAV
                                        :                .     . :   .                

Mb0117|M.bovis_AF2122/97            EHVEHALFAPRQ--------------------------------------
Rv0113|M.tuberculosis_H37Rv         EHVEHALFAPRQ--------------------------------------
MSMEG_0192|M.smegmatis_MC2_155      AAVQRHRRSPRRTSNNG---------------------------------
Mvan_2922|M.vanbaalenii_PYR-1       ARTRMALWEERRRGEVLP--------------------------------
MAB_0363c|M.abscessus_ATCC_199      AATGLGVTLEPTLEELSPMLAIIPLQLLAMQLAIGRGENPDVPRGLSKVT
                                      .                                               

Mb0117|M.bovis_AF2122/97            ---
Rv0113|M.tuberculosis_H37Rv         ---
MSMEG_0192|M.smegmatis_MC2_155      ---
Mvan_2922|M.vanbaalenii_PYR-1       ---
MAB_0363c|M.abscessus_ATCC_199      ETL