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M. smegmatis MC2 155 MSMEG_0129 (-)

annotation: cyclase/dehydrase family protein
coordinates: 149990 - 150424
length: 144

VSKTVEVAASAETITSIVSDFEAYPQWNPEIKGCWILARYNDGRPSQLRLDVEIQGQSGVFITAVYYPAE
NQIFTMLQQGDHFTKQEQRFSIVPLGPDSTLLQVDLDVEVKLPVPGPMVKKLAGETLEHLAKALEGRVEQ
LTQS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0129--100% (144)cyclase/dehydrase family protein
M. smegmatis MC2 155MSMEG_5736-2e-1327.74% (137) cyclase/dehydrase
M. smegmatis MC2 155MSMEG_4251-6e-0620.86% (139) cyclase/dehydrase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0169TB18.51e-4459.03% (144) hypothetical protein Mb0169
M. gilvum PYR-GCKMflv_0716-6e-6177.08% (144) cyclase/dehydrase
M. tuberculosis H37RvRv0164TB18.51e-4459.03% (144) hypothetical protein Rv0164
M. leprae Br4923MLBr_02629-6e-4663.12% (141) hypothetical protein MLBr_02629
M. abscessus ATCC 19977MAB_4572c-8e-3653.90% (141) hypothetical protein MAB_4572c
M. marinum MMMAR_0407-8e-4460.56% (142) hypothetical protein MMAR_0407
M. avium 104MAV_5019-1e-4358.87% (141) cyclase/dehydrase superfamily protein
M. thermoresistible (build 8)TH_0157-3e-5975.89% (141) CONSERVED HYPOTHETICAL PROTEIN TB18.5
M. ulcerans Agy99MUL_1057-7e-4461.27% (142) hypothetical protein MUL_1057
M. vanbaalenii PYR-1Mvan_0129-8e-5670.83% (144) cyclase/dehydrase

CLUSTAL 2.0.9 multiple sequence alignment


Mb0169|M.bovis_AF2122/97            MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVK
Rv0164|M.tuberculosis_H37Rv         MTAISCSPRPRYASRMPVLSKTVEVTADAASIMAIVADIERYPEWNEGVK
MMAR_0407|M.marinum_M               --------MPRYASPMPVLSKTVEVSADAGSIMGIVADIERYPEWNEGVK
MUL_1057|M.ulcerans_Agy99           --------MPRYASPMPVLSKTVEVSADAGSIMGIVADIERYPEWNEGVK
MAV_5019|M.avium_104                ---------------MPVLSKTVEVNTDAAAIMAIVADFERYPEWSDGVT
MLBr_02629|M.leprae_Br4923          -----MGSVPGYASPMPVMSKTVEVRATAASIMAIVTDFEAYPQWNDGVK
Mflv_0716|M.gilvum_PYR-GCK          ---------------MPLVSKTVEVSASAETIMAIVADFEKYPEWNEEIK
Mvan_0129|M.vanbaalenii_PYR-1       ---------------MPLVSKTVEVEAAAETIMGIVADFESYPQWNEEIK
TH_0157|M.thermoresistible__bu      ------------------VSKTVEVAAPADRIMAIVADFESYPLWNQEIK
MSMEG_0129|M.smegmatis_MC2_155      ------------------MSKTVEVAASAETITSIVSDFEAYPQWNPEIK
MAB_4572c|M.abscessus_ATCC_199      ---------------MPVVSQTVEVAAPPQVIVSIVTNYEAYPEWNKEIA
                                                      :*:**** : .  * .**:: * ** *.  : 

Mb0169|M.bovis_AF2122/97            GAWVLARYDDGRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGEL
Rv0164|M.tuberculosis_H37Rv         GAWVLARYDDGRPSQVRLDTAVQGIEGTYIHAVYYPGENQIQTVMQQGEL
MMAR_0407|M.marinum_M               GAWVLARYDDGRPSQVRLDASVQGFEGVYIHAVYYPGENQIQTVMQQGDL
MUL_1057|M.ulcerans_Agy99           GAWVLARYDDGRPSQVRLDASVQGFEGVYIHAVYYPGENQIQTVMQQGDL
MAV_5019|M.avium_104                GCWVLARYDDGRPSQLRLDAAYQGFEGVYIQAVYYPGPNQIQTVMQQGEL
MLBr_02629|M.leprae_Br4923          GVWVLARYDDGRPSQLRLDTEIQGTKCTYIQAVYYPATNQIQTIMQQGDL
Mflv_0716|M.gilvum_PYR-GCK          GCWILARYNDGRPSQLRLDVVVQGQAGTFITAVYYPAENQIFTMLQQGDH
Mvan_0129|M.vanbaalenii_PYR-1       GCWVLARYNDGRPSQLRLDVVVQGQAGTFITAVYYPGENQIYTVLQQGDH
TH_0157|M.thermoresistible__bu      GCWVLARYNDGRPSQLRLDVVVQGQSGTFITAVYYPAPNQIFTMLQQGDH
MSMEG_0129|M.smegmatis_MC2_155      GCWILARYNDGRPSQLRLDVEIQGQSGVFITAVYYPAENQIFTMLQQGDH
MAB_4572c|M.abscessus_ATCC_199      SVDILQRLPDGRPHIVRLKVETSGMSSTNVAEIAYLNAAQVATRLLESDI
                                    .  :* *  ****  :**..  .*   . :  : *    *: * : :.: 

Mb0169|M.bovis_AF2122/97            FAKQEQLFSVVATGA-ASLLTVDMDVQVTMPVPEPMVKMLLNNVLEHLAE
Rv0164|M.tuberculosis_H37Rv         FAKQEQLFSVVATGA-ASLLTVDMDVQVTMPVPEPMVKMLLNNVLEHLAE
MMAR_0407|M.marinum_M               FLKQEQLFSVVEAGA-ASLLTVDIDVEPSMPVPPPMVKLLLNNVLEQLAA
MUL_1057|M.ulcerans_Agy99           FLKQEQLFSVVEAGA-VSLLTVDIDVEPSMPVPPPMVKLLLNNVLEQLAA
MAV_5019|M.avium_104                FKKQEQLFSVVEMGA-SSLLTVDIDVEPSMPVPAPMVKSMLNNVLDHLAD
MLBr_02629|M.leprae_Br4923          FTKQEQLFSAVEIGA-ASLLTVDIDVESSMPVPAPMVKALLNNVLDNLAE
Mflv_0716|M.gilvum_PYR-GCK          FTKQEQRFAVVPMGP-TSLLTVDLDVEVSMPVPAVMVKKVIGDTLDYLAE
Mvan_0129|M.vanbaalenii_PYR-1       LSKQEQRFSVVAMGA-TSLLTVDLEVEVKMAVPNAMVKKIVGDTLDYLAD
TH_0157|M.thermoresistible__bu      FEKQEQTFSVVAMGPNSSLLTVDLDVETKMPVPKSMVKKLAGDTLDYLAD
MSMEG_0129|M.smegmatis_MC2_155      FTKQEQRFSIVPLGPDSTLLQVDLDVEVKLPVPGPMVKKLAGETLEHLAK
MAB_4572c|M.abscessus_ATCC_199      FEKQEQTFSIVPMGQ-TCLLTVDMDVETKLPIPKPMVKKLANQVLEHLAE
                                    : **** *: *  *    ** **::*: .:.:*  *** : .:.*: ** 

Mb0169|M.bovis_AF2122/97            NLKQRAEQLAAS--------------
Rv0164|M.tuberculosis_H37Rv         NLKQRAEQLAAS--------------
MMAR_0407|M.marinum_M               NLKLRAEQLTAG--------------
MUL_1057|M.ulcerans_Agy99           NLKLRAEQLTAG--------------
MAV_5019|M.avium_104                NLKQRAEQLAAN--------------
MLBr_02629|M.leprae_Br4923          NLKLRAEQLAAN--------------
Mflv_0716|M.gilvum_PYR-GCK          NLKTRAEHLTAS--------------
Mvan_0129|M.vanbaalenii_PYR-1       NLKTRAEQLAST--------------
TH_0157|M.thermoresistible__bu      NLKTRAEQLAS---------------
MSMEG_0129|M.smegmatis_MC2_155      ALEGRVEQLTQS--------------
MAB_4572c|M.abscessus_ATCC_199      GLKGRAEAIASGQLQPAPVQQPPTQA
                                     *: *.* ::