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APIFAAAVAIGMVSACGSESEPAAESGATTISHKFGETTVPENPSRVVTVGWTDQDFVLPFGVVPVSARE FSENYNDLPWVQEATGGKGIPTWGSDSIDFEAIAAQKPDLILAIYETIDQQTYDRLSQIAPTVIQSADYA DEETPWDVQLLTTGKALGKEAEAKELLDEVQGKIDEARRNNPEFEGKTLVVDFGPADGGHYLLGENDPRR SLFTALGFQTQDVVGDVSEEKLDLLDRDVLFVNGATKDELITSPAFERLGVVRDGRTLYTTFESKLSDAL TYSGPDSLQYALDVLTPQLANALNGRPVADLSNA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0020 | - | - | 100% (315) | periplasmic binding protein |
| M. smegmatis MC2 155 | MSMEG_0438 | - | 4e-36 | 32.79% (308) | periplasmic binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0271c | - | 6e-28 | 28.48% (316) | periplasmic IRON-transport lipoprotein |
| M. gilvum PYR-GCK | Mflv_0375 | - | 6e-36 | 33.66% (306) | periplasmic binding protein |
| M. tuberculosis H37Rv | Rv0265c | - | 6e-28 | 28.48% (316) | periplasmic IRON-transport lipoprotein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4390 | - | 5e-34 | 33.02% (318) | ABC transporter periplasmic substrate-binding protein |
| M. marinum M | MMAR_0525 | - | 2e-30 | 29.45% (309) | periplasmic iron-transport lipoprotein |
| M. avium 104 | MAV_4895 | - | 4e-29 | 29.15% (319) | periplasmic binding protein |
| M. thermoresistible (build 8) | TH_1824 | fecB | 1e-11 | 28.52% (277) | PROBABLE FEIII-DICITRATE-BINDING PERIPLASMIC LIPOPROTEIN |
| M. ulcerans Agy99 | MUL_1188 | - | 2e-31 | 29.77% (309) | periplasmic iron-transport lipoprotein |
| M. vanbaalenii PYR-1 | Mvan_0308 | - | 3e-31 | 32.13% (305) | periplasmic binding protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0271c|M.bovis_AF2122/97 --------------------------------------------------
Rv0265c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0525|M.marinum_M --------------------------------------------------
MUL_1188|M.ulcerans_Agy99 --------------------------------------------------
MAV_4895|M.avium_104 --------------------------------------------------
Mflv_0375|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0308|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4390|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_0020|M.smegmatis_MC2_155 --------------------------------------------------
TH_1824|M.thermoresistible__bu VPLEPGPDRRRGGVTVGDVIVPGRRIRVIAGMVSLVTAVFLTMATGCGAP
Mb0271c|M.bovis_AF2122/97 -------MRQGCSRRGFLQVAEAAAATG-LFAGCSSPKPPPGTPGGAAVT
Rv0265c|M.tuberculosis_H37Rv -------MRQGCSRRGFLQVAEAAAATG-LFAGCSSPKPPPGTPGGAAVT
MMAR_0525|M.marinum_M -------MQQGWSRRGFLQVAAATGLLASGVAACSSSKPQAGTADTGAVT
MUL_1188|M.ulcerans_Agy99 -------MQQGWSRRGFLQVAAATGLLASGVAACSSSKPQAGTADTGAVT
MAV_4895|M.avium_104 -------------------MAATAGAAG-LSAGCSAHQPPPGGAGPGSVT
Mflv_0375|M.gilvum_PYR-GCK ----------MWSRRSFLGLTAGAAATL---TACGQDKP-GTVAGDGSVT
Mvan_0308|M.vanbaalenii_PYR-1 -------MATLVPRRRFLTMSAGAAALL---TACGSEKP-GAIASDGSVT
MAB_4390|M.abscessus_ATCC_1997 ------MPPGMITRRGLLAAGAALAAST--ALASCAKESAPTSERDGTAF
MSMEG_0020|M.smegmatis_MC2_155 ----------------MAPIFAAAVAIG---MVSACGSESEPAAESGATT
TH_1824|M.thermoresistible__bu QGAEPAPPRETVITSTTEIAGAGVLGNQRRPDESCAAEPAAPDPGPPVRD
. .
Mb0271c|M.bovis_AF2122/97 ITHLFGQTVIKEPPKRVVSAGYTEQDDLLAVDVVPIAVTDWFGDQPFAVW
Rv0265c|M.tuberculosis_H37Rv ITHLFGQTVIKEPPKRVVSAGYTEQDDLLAVDVVPIAVTDWFGDQPFAVW
MMAR_0525|M.marinum_M ITHLFGQTVIKEPPKRVVSAGFTEQDDLLALGVVPIAVTRWFGDQPFAVW
MUL_1188|M.ulcerans_Agy99 ITHLFGQTVIKEPPKRVVSAGFTEQDDLLALGVVPIAVTRWFGDQPFAVW
MAV_4895|M.avium_104 VTHLFGQTVVKEPPKRVVSAGYTEQDDLLAVGVVPIAVTNWFGDQPFAVW
Mflv_0375|M.gilvum_PYR-GCK VAHVFGETKIPVPPTRVVSAGLTDADDLLALGVVPIAVTDWFGAEPFGVW
Mvan_0308|M.vanbaalenii_PYR-1 VRHAFGETKIPKPPTRVVSAGLTDADDLLALGVVPIAVTDWFGAEPFGVW
MAB_4390|M.abscessus_ATCC_1997 IKHAFGTTEVKAPPKRIISAGYTGHDYLLALGIVPVAVTEWYGGFPFATW
MSMEG_0020|M.smegmatis_MC2_155 ISHKFGETTVPENPSRVVTVGWTDQDFVLPFGVVPVSAREFSEN--YNDL
TH_1824|M.thermoresistible__bu VAHAAGSTAVPADPQRIVVLSGDQLDALCALGLQSRIVAAAVPEDTGVQP
: * * * : * *:: . * : ...: . .
Mb0271c|M.bovis_AF2122/97 PWAAPKLGGARPAVLNLDNGIQIDRIAALKPDLIVAINAGVDADTYQQLS
Rv0265c|M.tuberculosis_H37Rv PWAAPKLGGARPAVLNLDNGIQIDRIAALKPDLIVAINAGVDADTYQQLS
MMAR_0525|M.marinum_M PWAQPKLGAAQPVVLSLDDGIQVDQIANLKPDLIVAINAGVDAETYQKLS
MUL_1188|M.ulcerans_Agy99 PWAQPKLGAAQPVVLSLDDGIQVDQIANLKPDLIVAINAGVDAETYQKLS
MAV_4895|M.avium_104 PWAADKLGGAQPTVLNLDNGIPVDQIAGLKPDLIVAINAGLDADTYQKLS
Mflv_0375|M.gilvum_PYR-GCK PWARPQLGAAQPVVLSLADGVQVEQIASLNPDLIIATDAGLDQDTYTRLS
Mvan_0308|M.vanbaalenii_PYR-1 PWAQPRLGGAQPVVLSLADGIQVEQIAGLTPDLIVATDAGLDQDTYTRLS
MAB_4390|M.abscessus_ATCC_1997 PWATERLGGATPEVLTLTDGLMIDKIASLKPDLIVAADAGLDQDTYTKLS
MSMEG_0020|M.smegmatis_MC2_155 PWVQEATGGKGIPTWGSDS-IDFEAIAAQKPDLILAIYETIDQQTYDRLS
TH_1824|M.thermoresistible__bu AYLGTVIH--ELPAAGTRTEPDLDAIRAARPDLILGS-QALTPADYPRLA
.: . .: * ****:. : * :*:
Mb0271c|M.bovis_AF2122/97 AIAPTVAQSGGDAFFEP-WKDQARSIGQAVFAADRMRSLIE--AVDQKFA
Rv0265c|M.tuberculosis_H37Rv AIAPTVAQSGGDAFFEP-WKDQARSIGQAVFAADRMRSLIE--AVDQKFA
MMAR_0525|M.marinum_M AIAPTIPQSGGDAFFEP-WKLQASTVGEAVFQSAQMKSLID--AVGQKFA
MUL_1188|M.ulcerans_Agy99 AIAPTIPQSGGDAFFEP-WKLQASTVGEAVFQRAQMKSLID--AVDQKFA
MAV_4895|M.avium_104 AIAPTVAQSDGDAFFEP-WKEQAAAVGQAVFAAEKMKSLVA--GVDQKFT
Mflv_0375|M.gilvum_PYR-GCK QIAPTVAQSGRAAFFEP-WRDQATAIGQAVFRHDDMQKLIA--DVDAQFS
Mvan_0308|M.vanbaalenii_PYR-1 EIAPTIAQSGSAAFFEP-WRDQAGAIGQAVLRHDDMQKLIT--DVDAKFT
MAB_4390|M.abscessus_ATCC_1997 GIAPTIAQAGKYAFFEP-WKDQAKAIGQAVFKPAEMDAVVK--AVDNKFS
MSMEG_0020|M.smegmatis_MC2_155 QIAPTVIQSADYADEETPWDVQLLTTGKALGKEAEAKELLD--EVQGKID
TH_1824|M.thermoresistible__bu AIAPTVFTGAP----GPDWQGNLRTVGAATGRSAAADALLDGFAEDARRT
****: . . * : : * * :: :
Mb0271c|M.bovis_AF2122/97 AVAQRHPRWRGKKALLLQG--RLWQGNVVATLAGWRTDFLNDMGLVIADS
Rv0265c|M.tuberculosis_H37Rv AVAQRHPRWRGKKALLLQG--RLWQGNVVATLAGWRTDFLNDMGLVIADS
MMAR_0525|M.marinum_M AVAQQHPQWMGKKALLLQG--RLWQGNVIATMAGWRTDFLNEMGLVISEG
MUL_1188|M.ulcerans_Agy99 AAAQQHPQWMGKKALLLQG--RLWQGNVIATMAGWRTDFLNEMGLVVSEG
MAV_4895|M.avium_104 DIGKKNPQWTGKKALLMHG--ALWQGTVVATMAGWRTDFLNQMGLVIADS
Mflv_0375|M.gilvum_PYR-GCK AAKDAHPEFSGKTALLLAG--SVTGDGVRVTGPAWRREFLTAMGLTVLD-
Mvan_0308|M.vanbaalenii_PYR-1 GVKDSHPQFAGKKALLLAG--TLFRDSVQVSGPSWRHEFLTQMGLTVLE-
MAB_4390|M.abscessus_ATCC_1997 SAASAHTGFKDKKAIYLQG--ELLDGQAIAFRSGPRTGFLSGLGLITPPD
MSMEG_0020|M.smegmatis_MC2_155 EARRNNPEFEGKTLVVDFG--PADGGHYLLGENDPRRSLFTALGFQTQD-
TH_1824|M.thermoresistible__bu GAQNDAAHFQASVVQLTDTTVRVFGADTFPGSVLAAVGLDRPAAQRFTDR
. : . : .
Mb0271c|M.bovis_AF2122/97 IKPFAV-DQRGVIPRDHIKAVLDAADVLIWMTESPEDEKALLADPEIAAS
Rv0265c|M.tuberculosis_H37Rv IKPFAV-DQRGVIPRDHIKAVLDAADVLIWMTESPEDEKALLADPEIAAS
MMAR_0525|M.marinum_M IKPFAV-DQRGVIPRDHIKEVLDSADVLIWLTESPEDEQALLADPEIAAS
MUL_1188|M.ulcerans_Agy99 IKPFAV-DQRGVIPRDHIKEVLDSADVLIWLTESPEDEQALLADPEIAAS
MAV_4895|M.avium_104 IKPFGT-DQRAVIPRDHIKSVLESADVVIWTTQNPDDQKALLADPEVAGS
Mflv_0375|M.gilvum_PYR-GCK -------TDD-EIPRDRMPDVLDEADVLIWTTESDEEQASLLADPAIADL
Mvan_0308|M.vanbaalenii_PYR-1 -------TDDALIPRDRIAEVLGAADVLIWTTESDQEQAALLADPAIAGI
MAB_4390|M.abscessus_ATCC_1997 LETYAKGDQLAYLAADRLSTVLAEADVLLWGTESDEQIAALKADPAITTL
MSMEG_0020|M.smegmatis_MC2_155 ------------VVGDVSEEKLDLLDRDVLFVNG-ATKDELITSPAFERL
TH_1824|M.thermoresistible__bu PYIDIGATDAELADADFGIAEGDIVYVSFASPAARDRARTVFTSDAWRRL
* . : :.
Mb0271c|M.bovis_AF2122/97 QATAQRRHIFTSKE--QAGAIAFSSVLSYPVVAEQLPPQISQILGA----
Rv0265c|M.tuberculosis_H37Rv QATAQRRHIFTSKE--QAGAIAFSSVLSYPVVAEQLPPQISQILGA----
MMAR_0525|M.marinum_M AATEQKRHVFTTGD--QAGAIAFASPLSYPVVADELPALIAKVLG-----
MUL_1188|M.ulcerans_Agy99 AATEQKRHVFTTGD--QAGAIAFASPLSYPVVADELPALIAKVLG-----
MAV_4895|M.avium_104 LTTAQNRHIFTTKD--QAGAIAFASPLSYPVIADQLPPQLTKILG-----
Mflv_0375|M.gilvum_PYR-GCK RATTRSSHVFTGKE--LAGAIAYASTLSYPVLADRLPPMLADALT-----
Mvan_0308|M.vanbaalenii_PYR-1 PARR---HVFTGKE--LAGAIAYASTLSYPVVADRLPPMLAAAVG-----
MAB_4390|M.abscessus_ATCC_1997 GPSLLDRSIFTSKE--LGGAINFSSPLSLTYVVDNLVPQLARILG-----
MSMEG_0020|M.smegmatis_MC2_155 GVVRDGRTLYTTFESKLSDALTYSGPDSLQYALDVLTPQLANALNGRPVA
TH_1824|M.thermoresistible__bu SATKDNRVFTVNNEVWQTGQNIVAARG----ILDDLQWVNAPIN------
. . : . :. : * :
Mb0271c|M.bovis_AF2122/97 -----
Rv0265c|M.tuberculosis_H37Rv -----
MMAR_0525|M.marinum_M -----
MUL_1188|M.ulcerans_Agy99 -----
MAV_4895|M.avium_104 -----
Mflv_0375|M.gilvum_PYR-GCK -----
Mvan_0308|M.vanbaalenii_PYR-1 -----
MAB_4390|M.abscessus_ATCC_1997 -----
MSMEG_0020|M.smegmatis_MC2_155 DLSNA
TH_1824|M.thermoresistible__bu -----