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VTHPAPTQSPTADPAREALLGLRAEIAKAVVGQEGVISGLVIALLCRGHVLLEGVPGVAKTLMVRALAAA LQLEFKRVQFTPDLMPGDVTGSLVYDAHSAEFAFRPGPVFTNLMLADEINRTPPKTQAALLEAMEERQVS VEGQAKPLPDPFIVAATQNPIEYEGTYQLPEAQLDRFLLKLNVGLPSRESEIAILGRHAHGFDPRDLSAI KPVAGPAELAAGREAVSRVLIADEVLGYIVDIVGATRSSPALQLGVSPRGATALLGTARSWAWLSGRNYV TPDDVKAMARPTLRHRIMLRPEAELEGATPDGVLDGILASVPVPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5202 | moxR2 | - | 100% (325) | methanol dehydrogenase transcriptional regulatory protein MoxR2 |
| M. marinum M | MMAR_1399 | moxR3 | 4e-81 | 51.50% (301) | methanol dehydrogenase transcriptional regulatory protein |
| M. marinum M | MMAR_2286 | moxR1 | 3e-64 | 40.54% (333) | transcriptional regulatory protein, MoxR1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3717 | moxR2 | 1e-164 | 88.45% (329) | putative methanol dehydrogenase transcriptional regulatory |
| M. gilvum PYR-GCK | Mflv_1337 | - | 1e-151 | 83.07% (319) | ATPase |
| M. tuberculosis H37Rv | Rv3692 | moxR2 | 1e-164 | 88.45% (329) | methanol dehydrogenase transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_01810 | moxR | 8e-65 | 42.90% (310) | MoxR homolog |
| M. abscessus ATCC 19977 | MAB_0389c | - | 1e-143 | 78.19% (321) | putative regulatory protein |
| M. avium 104 | MAV_0412 | - | 1e-163 | 88.38% (327) | ATPase family protein associated with various cellular |
| M. smegmatis MC2 155 | MSMEG_6219 | - | 1e-158 | 87.38% (325) | ATPase family protein associated with various cellular |
| M. thermoresistible (build 8) | TH_1715 | moxR2 | 1e-150 | 85.99% (307) | PROBABLE METHANOL DEHYDROGENASE TRANSCRIPTIONAL REGULATORY |
| M. ulcerans Agy99 | MUL_4275 | moxR2 | 1e-180 | 98.15% (325) | methanol dehydrogenase transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5455 | - | 1e-155 | 85.58% (319) | ATPase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1337|M.gilvum_PYR-GCK MTQSA--------------------------QHEG------------ARN
Mvan_5455|M.vanbaalenii_PYR-1 MTQPT--------------------------NHEG------------ARN
MMAR_5202|M.marinum_M MTHPA------PTQSP---------------TADP------------ARE
MUL_4275|M.ulcerans_Agy99 MTHPA------PTQSP---------------TTDP------------ARE
Mb3717|M.bovis_AF2122/97 MTQSASNPQAPPTQTPGAELPGYPPQAGGAPTAAPSGPHPHRAEAESARD
Rv3692|M.tuberculosis_H37Rv MTQSASNPQAPPTQTPGAELPGYPPQAGGAPTAAPSGPHPHRAEAESARD
MAV_0412|M.avium_104 MTQPT----QPVTASP---------------TAES------------ARE
TH_1715|M.thermoresistible__bu --------------------------------------------------
MSMEG_6219|M.smegmatis_MC2_155 MTQPA------TTVD-----------------ADT------------ARN
MAB_0389c|M.abscessus_ATCC_199 MTQAT------TTGS----------------SGET------------ARN
MLBr_01810|M.leprae_Br4923 MTSAGGLPVGADGCSGPGGQSGPRAHEAPPGGADG---------LVAEVH
Mflv_1337|M.gilvum_PYR-GCK ALMALRAEIGKVVVGQDAVVSGLVVALLCRGHVLLEGVPGVAKTLLVRTL
Mvan_5455|M.vanbaalenii_PYR-1 ALMALRAEIAKVVVGQDAVVSGLVIALLCRGHVLLEGVPGVAKTLLVRTL
MMAR_5202|M.marinum_M ALLGLRAEIAKAVVGQEGVISGLVIALLCRGHVLLEGVPGVAKTLMVRAL
MUL_4275|M.ulcerans_Agy99 ALLGLRAEIAKAVVGQEGVINGLVIALLCRGHVLLEGVPGVAKTLMVRAL
Mb3717|M.bovis_AF2122/97 ALLALRAEVAKAVVGQDGVISGLVIALLCRGHVLLEGVPGVAKTLIVRAM
Rv3692|M.tuberculosis_H37Rv ALLALRAEVAKAVVGQDGVISGLVIALLCRGHVLLEGVPGVAKTLIVRAM
MAV_0412|M.avium_104 ALLALRAELAKAVVGQEGVVSGLVIALLCRGHVLLEGVPGVAKTLLVRAL
TH_1715|M.thermoresistible__bu -LLALRQEIAKVVVGQDAVVSGLVIALLCRGHVLLEGVPGVAKTLLIRTL
MSMEG_6219|M.smegmatis_MC2_155 ALLALRNEIAKVVVGQDAVISGLVIALLCRGHVLLEGVPGVAKTLLVRTL
MAB_0389c|M.abscessus_ATCC_199 ALAALREQIAIVVVGQDSVVSGLVVALLCRGHVLLEGVPGVAKTLLVRTL
MLBr_01810|M.leprae_Br4923 TLERAIFEVKRVIVGQDQLVERMLVGLLSKGHVLLEGVPGVAKTLAVETF
* :: .:***: ::. :::.**.:*************** :.::
Mflv_1337|M.gilvum_PYR-GCK AAALQLDFTRVQFTPDLMPGDVTGSLVYDARTAEFEFRSGPVFTNLLLAD
Mvan_5455|M.vanbaalenii_PYR-1 AAALQLDFKRVQFTPDLMPGDVTGSLVYDARTAEFEFRAGPVFTNLMLAD
MMAR_5202|M.marinum_M AAALQLEFKRVQFTPDLMPGDVTGSLVYDAHSAEFAFRPGPVFTNLMLAD
MUL_4275|M.ulcerans_Agy99 GAALQLEFKRVQFTPDLMPGDVTGSLVYDVHSAEFAFRPGPVFTNLMLAD
Mb3717|M.bovis_AF2122/97 SAALQLEFKRVQFTPDLMPGDVTGSLVYDARTAEFVFRPGPVFTNLLLAD
Rv3692|M.tuberculosis_H37Rv SAALQLEFKRVQFTPDLMPGDVTGSLVYDARTAEFVFRPGPVFTNLLLAD
MAV_0412|M.avium_104 AAALQLEFKRVQFTPDLMPGDVTGSLVYDARTAAFVFRPGPVFTNLLLAD
TH_1715|M.thermoresistible__bu AAALQLDFKRVQFTPDLMPGDVTGSLVYDAKTARFEFRPGPVFTNLLLAD
MSMEG_6219|M.smegmatis_MC2_155 AAALQLEFKRVQFTPDLMPGDVTGSLVYDARTAEFEFRQGPVFTNLLLAD
MAB_0389c|M.abscessus_ATCC_199 SAALSLDFKRVQFTPDLMPGDVTGSLVYDARTAAFEFRAGPVFTNLLLAD
MLBr_01810|M.leprae_Br4923 ARVVGGTFARIQFTPDLVPTDIIGTRIYRQGKEEFDTELGPVVVNFLLAD
. .: * *:******:* *: *: :* . * . ***..*::***
Mflv_1337|M.gilvum_PYR-GCK EINRTPPKTQAALLEAMEERQVSVDGHPRPLPDPFIVAATQNPIEYEGTY
Mvan_5455|M.vanbaalenii_PYR-1 EINRTPPKTQAALLEAMEERQVSVDGQPRPLPDPFIVAATQNPIEYEGTY
MMAR_5202|M.marinum_M EINRTPPKTQAALLEAMEERQVSVEGQAKPLPDPFIVAATQNPIEYEGTY
MUL_4275|M.ulcerans_Agy99 EINRTPPKTQAALLEAMEERQVSVEGQAKPLPDPFIVAATQNPIEYEGTH
Mb3717|M.bovis_AF2122/97 EINRTPPKTQAALLEAMEERQVSVEGEPKPLPNPFIVAATQNPIEYEGTY
Rv3692|M.tuberculosis_H37Rv EINRTPPKTQAALLEAMEERQVSVEGEPKPLPNPFIVAATQNPIEYEGTY
MAV_0412|M.avium_104 EINRTPPKTQAALLEAMEERQVSVEGEAQPLPEPFIVAATQNPVEYEGTY
TH_1715|M.thermoresistible__bu EINRTPPKTQAALLEAMEERQVSVEGEARPLPDPFIVAATQNPIEYEGTY
MSMEG_6219|M.smegmatis_MC2_155 EINRTPPKTQAALLEAMEERQVSVDGQPRPLPDPFIVAATQNPIEYEGTY
MAB_0389c|M.abscessus_ATCC_199 EINRTPPKTQAALLEAMEERQVTVDGTPRPLPDPFIVAATQNPIEYEGTY
MLBr_01810|M.leprae_Br4923 EINRAPAKVQSALLEVMQERHVSIGGKTFPLPNPFLVMATQNPIEHEGVY
****:*.*.*:****.*:**:*:: * . ***:**:* *****:*:**.:
Mflv_1337|M.gilvum_PYR-GCK QLPEAQLDRFLLKLTVPLPPRDQEIAILSRHARGFDPRDLSFVQPVAGPA
Mvan_5455|M.vanbaalenii_PYR-1 QLPEAQLDRFLLKLNVPLPPRDQEIAILNRHANGFDPRDLSFVKPVAGPA
MMAR_5202|M.marinum_M QLPEAQLDRFLLKLNVGLPSRESEIAILGRHAHGFDPRDLSAIKPVAGPA
MUL_4275|M.ulcerans_Agy99 QLPEAQLDRFLLKLNVGLPSRESEIAILGRHAHGFDPRDLSAIKPVAGPA
Mb3717|M.bovis_AF2122/97 QLPEAQLDRFLLKLNVTLPARDSEIAILDRHAHGFDPRDLSAINPVAGPA
Rv3692|M.tuberculosis_H37Rv QLPEAQLDRFLLKLNVTLPARDSEIAILDRHAHGFDPRDLSAINPVAGPA
MAV_0412|M.avium_104 QLPEAQLDRFLLKLNVTLPPREAEIAILHRHAHGFDPRDLSVVQPVAGPA
TH_1715|M.thermoresistible__bu QLPEAQLDRFLLKLNVPLPPRDQEIAILSRHAQGFDPRDLSVVRPVAGPA
MSMEG_6219|M.smegmatis_MC2_155 QLPEAQLDRFLLKLNVPLPPREQEIAILSRHAHGFDPRNLSAVQPVAGPA
MAB_0389c|M.abscessus_ATCC_199 QLPEAQLDRFLMKLNVSLPERDQEIAILDRHAHGFDPRNLSHVTPVASAA
MLBr_01810|M.leprae_Br4923 LLPEAQRDRFLFKINVGYPSPEEEREIIYR--MGVTP---PVPKQILNAG
***** ****:*:.* * : * *: * *. * . : ...
Mflv_1337|M.gilvum_PYR-GCK ELAAGRDAVRQVLVADEVLGYIVDIVGATRNSPLL---------QLGVSP
Mvan_5455|M.vanbaalenii_PYR-1 ELAAGREAVRQVLVGDEVLGYIVDIVGATRNSPSL---------QLGVSP
MMAR_5202|M.marinum_M ELAAGREAVSRVLIADEVLGYIVDIVGATRSSPAL---------QLGVSP
MUL_4275|M.ulcerans_Agy99 ELAAGREAVSRVLIADEVLGYIVDIVGATRSSPAL---------QLGVSP
Mb3717|M.bovis_AF2122/97 ELAAGREAVRHVLVANEVLGYIVDIVGATRSSPAL---------QLGVSP
Rv3692|M.tuberculosis_H37Rv ELAAGREAVRHVLVANEVLGYIVDIVGATRSSPAL---------QLGVSP
MAV_0412|M.avium_104 DLAAGRDAVQQVRVADEVLGYIVDIVGATRSSPAL---------QLGVSP
TH_1715|M.thermoresistible__bu ELAAGREAVRQVRVADEVLGYIVDIAAATRQSPAL---------QLGVSP
MSMEG_6219|M.smegmatis_MC2_155 ELAAGRDAVSRVRVADEVLGYIVDIVGATRHSPAL---------QLGVSP
MAB_0389c|M.abscessus_ATCC_199 DLAAGRAAVGQVLVAPEVLAYVVDVIRATRQSPSL---------QLGASP
MLBr_01810|M.leprae_Br4923 DLLRLQEISANNFVHHALVDYVVRVVTATRHPEQLGMNDVKTWISFGASP
:* : . : :: *:* : *** . * .:*.**
Mflv_1337|M.gilvum_PYR-GCK RGATALLATARAWAWLSGRGYVTPDDVKAMARPTLRHRVALRPEAELEGA
Mvan_5455|M.vanbaalenii_PYR-1 RGATALLSTARSWAWLSGRGYVTPDDVKAMARPTLRHRVALRPEAELEGA
MMAR_5202|M.marinum_M RGATALLGTARSWAWLSGRNYVTPDDVKAMARPTLRHRIMLRPEAELEGA
MUL_4275|M.ulcerans_Agy99 RGATALLGTARSWAWLSGRNYVTPDDVKAMARPTLRHRIMLRLEAELEGA
Mb3717|M.bovis_AF2122/97 RGATALLGTARSWAWLSGRDYVTPDDVKAMARPTLRHRVMLRPEAELEGA
Rv3692|M.tuberculosis_H37Rv RGATALLGTARSWAWLSGRDYVTPDDVKAMARPTLRHRVMLRPEAELEGA
MAV_0412|M.avium_104 RGATALLATARSWSWLSGRNYVTPDDVKAMARPTLRHRVMLRPEAELEGA
TH_1715|M.thermoresistible__bu RGTTALLATARSWAWLSGRDYVTPDDVKAMARPTLRHRVMLRPEAELEGA
MSMEG_6219|M.smegmatis_MC2_155 RGATALLATSRSWAWLCGRNYVTPDDVKAMARSTLRHRIALRPDAELEGA
MAB_0389c|M.abscessus_ATCC_199 RAATALLATSRAWAWLSGRNYVTPDDVKAMARPTLRHRIGLRPEAELEGA
MLBr_01810|M.leprae_Br4923 RASLGIIKASRSLALVRGRDYVIPQDVIEVIPDVLRHRLVLTYNALADEI
*.: .:: ::*: : : **.** *:** : .****: * :* :
Mflv_1337|M.gilvum_PYR-GCK SADGVIEGILSAVPVPR------------------------
Mvan_5455|M.vanbaalenii_PYR-1 TADGVIEGILSAVPVPR------------------------
MMAR_5202|M.marinum_M TPDGVLDGILASVPVPR------------------------
MUL_4275|M.ulcerans_Agy99 TPDGVLDGILASVPVPR------------------------
Mb3717|M.bovis_AF2122/97 TPDGVLDGILASVPVPR------------------------
Rv3692|M.tuberculosis_H37Rv TPDGVLDGILASVPVPR------------------------
MAV_0412|M.avium_104 TCDGVLDGILASVPVPR------------------------
TH_1715|M.thermoresistible__bu NTDTVLEAILAAVPVPR------------------------
MSMEG_6219|M.smegmatis_MC2_155 TPDGVLDGILAAVPVPR------------------------
MAB_0389c|M.abscessus_ATCC_199 TSDRVLDGILVTVPVPR------------------------
MLBr_01810|M.leprae_Br4923 SPEIVINRVLQTVALPQVNSFPQQGHSVPSVTQAAAAASGR
. : *:: :* :*.:*: