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M. marinum M MMAR_5068 (fadE34)

annotation: acyl-CoA dehydrogenase FadE34
coordinates: 6147614 - 6149749
length: 711

VAIVSDQQLAARELVRDWARTAAAGEIPTAASREIERGNADAWRPVFTGLAELGLFGVAVPEDHGGAGGT
IEDLCAMIEEAAKALVPGPVASTAVATAVLAEAGAEPQLLAALASGDRFAGLALEGELQFDQNTSLASGS
APLVLGAIAGGVVLLPAGASWLLVDTTAEGVAVEPSAATDFSRPLARVVLAAAPALSLGELGQRVEDLTA
TVLAAEAAGVTRWALETAVAYAKVREQFGKPIGSFQAIKHLCAEMLCRAEQADVAAADAARAAAESDDQQ
FALAAALAAGIGISAAKANVKDCIQVLGGIGCTWEHDAHLYLRRAHSIGRFLGGAERWLRRVAALTQAGV
RRRLDIDLSEVADLRPEIAAAVADVAALPEQKRQVALAEAGLLAPHWPAPYGRGASPAEQLLIDQELAAA
GVVRPDLVIGWWAAPTILEHGTPEQIARFVPSTLRGDFLWCQLFSEPGAGSDLASLRTKAVRGDGGWLLT
GQKVWTSAAHKARWGVCLARTDPDAPKHKGITYFLLDMTAPGIEIRPLREITGDSLFNEVFLENVFIPDQ
MVVGAVNDGWRLARTTLANERVAMATGTALGNPMEELLEVLAELELDTGQQDRLARLIVATQTGALLDQR
IAQLVMGGRDPGAQSSVRKLIGVRYRQALAEYMMDVSAGGGLVENRAVFDFLNTRCLTIAGGTEQILLTV
AAERLLGLPR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_5068fadE34-100% (711)acyl-CoA dehydrogenase FadE34
M. marinum MMMAR_0530fadE6e-13841.27% (693) acyl-CoA dehydrogenase FadE6
M. marinum MMMAR_1625fadE22e-13742.11% (722) acyl-CoA dehydrogenase FadE22

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3604cfadE340.081.12% (715) acyl-CoA dehydrogenase FADE34
M. gilvum PYR-GCKMflv_1460-0.069.86% (720) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv3573cfadE340.081.12% (715) acyl-CoA dehydrogenase FADE34
M. leprae Br4923MLBr_00737fadE254e-1726.63% (368) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_0580-0.061.32% (711) acyl-CoA dehydrogenase FadE
M. avium 104MAV_0587-0.081.72% (711) putative acyl-CoA dehydrogenase
M. smegmatis MC2 155MSMEG_6041-0.069.41% (716) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_1744fadE340.072.73% (682) PROBABLE ACYL-CoA DEHYDROGENASE FADE34
M. ulcerans Agy99MUL_4144fadE340.099.02% (711) acyl-CoA dehydrogenase FadE34
M. vanbaalenii PYR-1Mvan_5311-0.072.28% (718) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1460|M.gilvum_PYR-GCK          ---MPVPTSATITDEQADARELVRSWATASGS----VEAAREVEQ----G
Mvan_5311|M.vanbaalenii_PYR-1       ---MSASTSAPTTDDQSAARDLVRTWAAASRA----VEAARDVEQ----G
MSMEG_6041|M.smegmatis_MC2_155      ---MSLLSAGAGTSEEFAARDMVRSWAAASGA----VAAVRESE-----T
TH_1744|M.thermoresistible__bu      ------------------------------------VSAVREVER----G
Mb3604c|M.bovis_AF2122/97           -------MVATVTDEQSAARELVRGWARTAASGAAATAAVRDMEYGFEEG
Rv3573c|M.tuberculosis_H37Rv        -------MVATVTDEQSAARELVRGWARTAASGAAATAAVRDMEYGFEEG
MMAR_5068|M.marinum_M               -------MVAIVSDQQLAARELVRDWARTAAAGEIPTAASREIER----G
MUL_4144|M.ulcerans_Agy99           -------MVAIVSDQQLAARELVRDWARTAAAGEIPTAASREIER----G
MAV_0587|M.avium_104                -------MVATVTDEQFAARALVRDWARNASTGPGGTAAIRDVEQ----G
MAB_0580|M.abscessus_ATCC_1997      MSVPSGLRASGSSEVQEAARDAVRQWARSAAV----IESVRKMES-----
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1460|M.gilvum_PYR-GCK          DAAAWQAPYGRLAELGIFGVALPEAHGGADGTVADLAAMVDEAAAALVPG
Mvan_5311|M.vanbaalenii_PYR-1       DPDAWRAPYAGLAELGIFGVALPEEHGGADGTVSDLAAMIDEAAAALVPG
MSMEG_6041|M.smegmatis_MC2_155      DPGAWRAAYQGFAELGIFGVAVPDELGGAGSTVADLAAMIDEAAAALVPG
TH_1744|M.thermoresistible__bu      RPDSWRGPFAGFAELGTFGVAVAEEHGGAGGTIADLCAMVDEAAAALVPG
Mb3604c|M.bovis_AF2122/97           NADAWRPVFAGLAGLGLFGVAVPEDCGGAGGSIEDLCAMVDEAARALVPG
Rv3573c|M.tuberculosis_H37Rv        NADAWRPVFAGLAGLGLFGVAVPEDCGGAGGSIEDLCAMVDEAARALVPG
MMAR_5068|M.marinum_M               NADAWRPVFTGLAELGLFGVAVPEDHGGAGGTIEDLCAMIEEAAKALVPG
MUL_4144|M.ulcerans_Agy99           NADAWRPVFTGLAELGLFGVAVPEDHGGAGGIIEDLCAMIEEAAKALVPG
MAV_0587|M.avium_104                NPDAWRPVFARLAELGIFGVAVPEEAGGAGGSVEDLCAMVEEAAKALIPG
MAB_0580|M.abscessus_ATCC_1997      EPDGWGPAYVGLAELGIFGVAVPEAAGGSGAGFDDMIAMVDEAAASLVPG
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1460|M.gilvum_PYR-GCK          PVATTALATLVLPDG--QADLLESLATGQRWAGVALNADLSYADGR--VS
Mvan_5311|M.vanbaalenii_PYR-1       PVATTALATLVLSGP--HADLLEELATGERTAGVTLTADLDYADGR--VS
MSMEG_6041|M.smegmatis_MC2_155      PVVTTALATLLVTD----TGLLEALMSGERTAGVALSADVTVVDGR--AS
TH_1744|M.thermoresistible__bu      PVATTALATLTVSD----PELLEAFAAGQRTAGVALGGEVRFADGR--AS
Mb3604c|M.bovis_AF2122/97           PVATTAVATLVVSDP----KLRSALASGERFAGVAIDGGVQVDPKTSTAS
Rv3573c|M.tuberculosis_H37Rv        PVATTAVATLVVSDP----KLRSALASGERFAGVAIDGGVQVDPKTSTAS
MMAR_5068|M.marinum_M               PVASTAVATAVLAEAGAEPQLLAALASGDRFAGLALEGELQFDQNTSLAS
MUL_4144|M.ulcerans_Agy99           PVASTAVATAVLAEAGAEPQLLAALASGDRFAGLALEGELQFDQNTSLAS
MAV_0587|M.avium_104                PVATTALATLVLSDA----ELLAALAAGERFAGLALQGDITFDGAASTAS
MAB_0580|M.abscessus_ATCC_1997      PVATSALVAVVLAADG-HEELVPPLAAGERTAGLALTGNLAIADGL--AS
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1460|M.gilvum_PYR-GCK          GTAAYVLGADESAVLLLPVGET-WLLVDAGADGVTVEPLQATDFSRPLAR
Mvan_5311|M.vanbaalenii_PYR-1       GSAPYVLGAAATGVLLLPAGDT-WLLVDAAADGVTVESLKATDFSRPLAR
MSMEG_6041|M.smegmatis_MC2_155      GTVEFVLGADAAGVLLLPAGDD-VLLLDAGADGVSVEPLTATDFSIPLAR
TH_1744|M.thermoresistible__bu      GTVPYVLGADPAGVLLLPAGTAGWVLVDAAADGVTLEPLEATDFSRPLAR
Mb3604c|M.bovis_AF2122/97           GTVGRVLGGAPGGVVLLPADGN-WLLVDTACDEVVVEPLRATDFSLPLAR
Rv3573c|M.tuberculosis_H37Rv        GTVGRVLGGAPGGVVLLPADGN-WLLVDTACDEVVVEPLRATDFSLPLAR
MMAR_5068|M.marinum_M               GSAPLVLGAIAGGVVLLPAGAS-WLLVDTTAEGVAVEPSAATDFSRPLAR
MUL_4144|M.ulcerans_Agy99           GSAPLVLGAIAGGVVLLPAGAS-WLLVDTTAEGVAVEPLAATDFSRPLAR
MAV_0587|M.avium_104                GTLPFVLGAADGGVLLLPADGR-WLVVDTASDGVHIEPLAATDFSRPLAR
MAB_0580|M.abscessus_ATCC_1997      GVLPAVLGGTADGVLLAPVPDG-WVLVDCAEAGVAVEAKKATDFSRPWVT
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1460|M.gilvum_PYR-GCK          VSFDGAPAEALPVSGQRVVDLAATVMAAESAGLARWLLHTATEYAKVREQ
Mvan_5311|M.vanbaalenii_PYR-1       VVLDGAPAEVLDVPSQQVVDMAATLLAAEAAGLARWLLDTATEYAKVREQ
MSMEG_6041|M.smegmatis_MC2_155      VELDNAPAEVLPVSRQRFSDLAATLLAAEAAGLARWTLNTATEYAKVREQ
TH_1744|M.thermoresistible__bu      VSLDSVAAQQLSIPSQRFEDLAATVLAAEAAGISRWLLHTATEYAKVREQ
Mb3604c|M.bovis_AF2122/97           MVLTSAPVTVLEVSGERVEDLAATVLAAEAAGVARWTLDTAVAYAKVREQ
Rv3573c|M.tuberculosis_H37Rv        MVLTSAPVTVLEVSGERVEDLAATVLAAEAAGVARWTLDTAVAYAKVREQ
MMAR_5068|M.marinum_M               VVLAAAPALSLGELGQRVEDLTATVLAAEAAGVTRWALETAVAYAKVREQ
MUL_4144|M.ulcerans_Agy99           VVLAAAPALSLGELGQRVEDLTATVLAAEAAGVTRWALETAVAYAKVREQ
MAV_0587|M.avium_104                VVLDSAPATVLAQTPERVEELAATVLAAEAAGITRWSLQTAVDYAKVREQ
MAB_0580|M.abscessus_ATCC_1997      VTLHGAAVRPVGLPAAVIADLSVVTLSAEAVGVARWALQTAVEYAKVREQ
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1460|M.gilvum_PYR-GCK          FGKPIGSFQAIKHMCAEMLLRSEQASVAAADAARAASDPAADG---AQLS
Mvan_5311|M.vanbaalenii_PYR-1       FGKPIGSFQAIKHMCAEMLLRSEQASVAAADAARAAGESDAD-----QLS
MSMEG_6041|M.smegmatis_MC2_155      FGKPIGSFQAIKHMCAEMLLRSEQIAVAAADAAKAVAESDGSDS-ATQLS
TH_1744|M.thermoresistible__bu      FGQPIGRFQAVKHMCAEMLLRSEQISVAAADAARAAAEYDDD-----QLS
Mb3604c|M.bovis_AF2122/97           FGKPIGSFQAVKHLCAQMLCRAEQADVAAADAARAAADSDGT-----QLS
Rv3573c|M.tuberculosis_H37Rv        FGKPIGSFQAVKHLCAQMLCRAEQADVAAADAARAAADSDGT-----QLS
MMAR_5068|M.marinum_M               FGKPIGSFQAIKHLCAEMLCRAEQADVAAADAARAAAESDDQ-----QFA
MUL_4144|M.ulcerans_Agy99           FGKPIGSFQAIKHLCAEMLCRAEQADVAAADAARAAAESDDQ-----QFA
MAV_0587|M.avium_104                FGKPIGSFQAIKHLCAEMLCRAEQAEVAAADAARAAAEDDPA-----QFS
MAB_0580|M.abscessus_ATCC_1997      FGKQIGSFQAIKHMCAEMLCRVEQADVAVWDAAGCAQDVLANKGDSQQLS
MLBr_00737|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_1460|M.gilvum_PYR-GCK          IAAALAASVGIEAAKANAKDCIQVLGGIGITWEHDAHLYLRRAYGIAQFL
Mvan_5311|M.vanbaalenii_PYR-1       IAAALAASVGIEAAKANAKDCIQVLGGIGITWEHDAHLYLRRAYGIAQFL
MSMEG_6041|M.smegmatis_MC2_155      IAAAVAVATGIDAAKANAKDCIQVLGGIGITWEHDAHLYLRRAYGIAHFL
TH_1744|M.thermoresistible__bu      IAAAVAAAAGIDAAQANSKDCIQVLGGIGITWEHDAHLYLRRAYGIAQFL
Mb3604c|M.bovis_AF2122/97           IAAAVAASIGIDAAKANAKDCIQVLGGIGCTWEHDAHLYLRRAHGIGGFL
Rv3573c|M.tuberculosis_H37Rv        IAAAVAASIGIDAAKANAKDCIQVLGGIGCTWEHDAHLYLRRAHGIGGFL
MMAR_5068|M.marinum_M               LAAALAAGIGISAAKANVKDCIQVLGGIGCTWEHDAHLYLRRAHSIGRFL
MUL_4144|M.ulcerans_Agy99           LAAALAASIGISAAKANVKDCIQVLGGIGCTWEHDAHLYLRRAHSIGRFL
MAV_0587|M.avium_104                LAAALAAATAITAVKANVKDCIQVLGGIGCTWEHDAHLYLRRAHAIGRFL
MAB_0580|M.abscessus_ATCC_1997      LAAAVAAAVAVDAAVANTKDCIQILGGIGFTWEHDAHLYLRRAYALQSFV
MLBr_00737|M.leprae_Br4923          ---------------------------------------------MVGWS
                                                                                 :  : 

Mflv_1460|M.gilvum_PYR-GCK          GGRSHWLRRVAALTQQGVRRELHIDLESVADLRPEIASAVAEVAAAPEDG
Mvan_5311|M.vanbaalenii_PYR-1       GGRSRWLRRVAALTQQGVRRELHIDLESVAGLRPEIVSAVAEVAAAPEDK
MSMEG_6041|M.smegmatis_MC2_155      GGSRRWVRRVAALTRQGARRDIDIDLESVADLRPEISAAVAEVAALPEEK
TH_1744|M.thermoresistible__bu      GGRPRWLRRVAALTQRGVRRELRIDLESVEHLRPEIRSLVADVAALPVEK
Mb3604c|M.bovis_AF2122/97           GGSGRWLRRVTALTQAGVRRRLGVDLAEVAGLRPEIAAAVAEVAALPEEK
Rv3573c|M.tuberculosis_H37Rv        GGSGRWLRRVTALTQAGVRRRLGVDLAEVAGLRPEIAAAVAEVAALPEEK
MMAR_5068|M.marinum_M               GGAERWLRRVAALTQAGVRRRLDIDLSEVADLRPEIAAAVADVAALPEQK
MUL_4144|M.ulcerans_Agy99           GGAERWLRRVAALTQAGVRRRLDIDLSEVADLRPEIVAAVADVAALPEQK
MAV_0587|M.avium_104                GGAERWLRRITALTQAGVRRRLGIDLTEVEDQRPQIAEAVARIAALPAEQ
MAB_0580|M.abscessus_ATCC_1997      GKPAVWRRKAAALTIGGIRRSLTIDLGEVESQRAEVAGQVAEIASAPKAE
MLBr_00737|M.leprae_Br4923          GNP-----LFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
                                    *           :.    :. :   :  :   .       .   :     

Mflv_1460|M.gilvum_PYR-GCK          RQVALAETGLLAPHWPKPYG--RAAGPAEQLLIDQELASAGVVRPDLVIG
Mvan_5311|M.vanbaalenii_PYR-1       RQVALAEARLLAPHWPPPHG--RAAGPAEQLLIDQELAAAGVVRPDLVIG
MSMEG_6041|M.smegmatis_MC2_155      RQVALAESGLLAPHWPKPYG--RNASPAEQLLIDQELAAAEVERPDLVIG
TH_1744|M.thermoresistible__bu      RQAALADAGLQAPHWPRPYG--RDASPAEQLLIDQELAAAGVERPDLVIG
Mb3604c|M.bovis_AF2122/97           RQVALADTGLLAPHWPAPYG--RGASPAEQLLIDQELAAAKVERPDLVIG
Rv3573c|M.tuberculosis_H37Rv        RQVALADTGLLAPHWPAPYG--RGASPAEQLLIDQELAAAKVERPDLVIG
MMAR_5068|M.marinum_M               RQVALAEAGLLAPHWPAPYG--RGASPAEQLLIDQELAAAGVVRPDLVIG
MUL_4144|M.ulcerans_Agy99           RQEALAEAGLLAPHWPAPYG--RGASPAEQLLIDQELAAAGVVRPDLVIG
MAV_0587|M.avium_104                RQAALAEAGLQAPHWPAPYG--RGASPAEQLLIDQELAAAGVARPDLVIG
MAB_0580|M.abscessus_ATCC_1997      HQVRLAEAGFLAPHWPAPYG--LGAGAAQQLLIDQELHAAGVNRPDLVIG
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
                                        *  : : * * *  :*     . *  ::*::            .:.

Mflv_1460|M.gilvum_PYR-GCK          WWAVPTILEHGSPELIEQFVPPTLRGELTWCQLFSEPGAGSDLAALRMKA
Mvan_5311|M.vanbaalenii_PYR-1       WWAVPTILEHGSPEQVEQFVPPTLRGELTWCQLFSEPGAGSDLAALRTKA
MSMEG_6041|M.smegmatis_MC2_155      WWAVPTILEHGSPEQIEQFVPATLRGDLFWCQLFSEPGAGSDLAALRTKA
TH_1744|M.thermoresistible__bu      WWAVPTILSHGSPEQIERFVSPTLRGELEWCQLFSEPGAGSDLAALRTKA
Mb3604c|M.bovis_AF2122/97           WWAAPTILEHGTPEQIERFVPATMRGEFLWCQLFSEPGAGSDLASLRTKA
Rv3573c|M.tuberculosis_H37Rv        WWAAPTILEHGTPEQIERFVPATMRGEFLWCQLFSEPGAGSDLASLRTKA
MMAR_5068|M.marinum_M               WWAAPTILEHGTPEQIARFVPSTLRGDFLWCQLFSEPGAGSDLASLRTKA
MUL_4144|M.ulcerans_Agy99           WWAAPTILEHGTPEQIARFVPSTLRGDFLWCQLFSEPGAGSDLASLRTKA
MAV_0587|M.avium_104                WWAAPTILEHGTPEQIERFVPGTLRGEFLWCQLFSEPGAGSDLASLRTKA
MAB_0580|M.abscessus_ATCC_1997      WWAAPTILEHGTPEQIAQFVAPTLRGEIEWCQLFSEPGAGSDLAALRTKA
MLBr_00737|M.leprae_Br4923          KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
                                      ..  :: :*: *   :.:.         .  :**  **** *::* :*

Mflv_1460|M.gilvum_PYR-GCK          VRAEGASASGAKVSGWKLTGQKVWTSAAQKAHWGVCLARTDPEAAKHKGI
Mvan_5311|M.vanbaalenii_PYR-1       VRVDDASASGASGPGWKLTGQKVWTSAAQKAHWGVCLARTDPDAPKHKGI
MSMEG_6041|M.smegmatis_MC2_155      VRAEGPNGE----PGWKLTGQKVWTSAAQNAHWGVCLARTDPDAPKHKGI
TH_1744|M.thermoresistible__bu      VRVDG---------GWRLTGQKVWTSAAHKADWGVCLARTDPDAPKHKGI
Mb3604c|M.bovis_AF2122/97           VRADG---------GWLLTGQKVWTSAAHKARWGVCLARTDPDAPKHKGI
Rv3573c|M.tuberculosis_H37Rv        VRADG---------GWLLTGQKVWTSAAHKARWGVCLARTDPDAPKHKGI
MMAR_5068|M.marinum_M               VRGDG---------GWLLTGQKVWTSAAHKARWGVCLARTDPDAPKHKGI
MUL_4144|M.ulcerans_Agy99           VRGDG---------GWLLTGQKVWTSAAHKARWGVCLARTDPDAPKHKGI
MAV_0587|M.avium_104                VRTDG---------GWLLTGQKVWTSAAHKARWGVCLARTDPDAPKHKGI
MAB_0580|M.abscessus_ATCC_1997      TRVDG---------GWKLDGQKVWNSKAQIADWAICLARTNPDVPKHKGI
MLBr_00737|M.leprae_Br4923          KADGD---------DWILNGFKCWITNGGKSTWYTVMAVTDPDK-GANGI
                                        .         .* * * * * : .  : *   :* *:*:    :**

Mflv_1460|M.gilvum_PYR-GCK          TYFLIDMKSPGIVIRPLREITG--DELFNEVFFDDVFVPDEMVVGEVNQG
Mvan_5311|M.vanbaalenii_PYR-1       TYFLIDMKSPGIVIRPLREITG--DELFNEVFFDDVFVPDEMVVGQVNDG
MSMEG_6041|M.smegmatis_MC2_155      TYFLVDMKTPGIVIRPLREITG--DELFNEVFFDDVFVPDTMVVGTVNDG
TH_1744|M.thermoresistible__bu      TYFLVDMKSPGIEIRPLREITG--DELFNEVFFDEVFVPDEMVVGQVNDG
Mb3604c|M.bovis_AF2122/97           TYFLVDMTTPGIEIRPLREITG--DSLFNEVFLDNVFVPDEMVVGAVNDG
Rv3573c|M.tuberculosis_H37Rv        TYFLVDMTTPGIEIRPLREITG--DSLFNEVFLDNVFVPDEMVVGAVNDG
MMAR_5068|M.marinum_M               TYFLLDMTAPGIEIRPLREITG--DSLFNEVFLENVFIPDQMVVGAVNDG
MUL_4144|M.ulcerans_Agy99           TYFLLDMTAPGIEIRPLREITG--DSLFNEVFLENVFIPDQMVVGAVNDG
MAV_0587|M.avium_104                TYFLVDMSAPGIEIRPLREITG--DSLFNEVFLDNVFVPDEMVVGEVNDG
MAB_0580|M.abscessus_ATCC_1997      TYFLLDMKTPGITVRPLREITG--EEMFNEVFLDGVIVPDENVVGSVDDG
MLBr_00737|M.leprae_Br4923          SAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTG
                                    : *::.    *: : * .:  *   .  .*::::   :*.  ::*  . *

Mflv_1460|M.gilvum_PYR-GCK          WRLARTTLANER---VAMAQGTALGNPMEELLR------VIAELDVDGAQ
Mvan_5311|M.vanbaalenii_PYR-1       WRLARTTLANER---VAMAQGTALGNPMEELLR------VVAQLEVDGAQ
MSMEG_6041|M.smegmatis_MC2_155      WRLARTTLANER---VAMAGGTALGNPMEEVLRA-----VEAQPEFDPAD
TH_1744|M.thermoresistible__bu      WRLARTTLANER---VAMAQGTALGNPMEELLR------TVTDLELDVAE
Mb3604c|M.bovis_AF2122/97           WRLARTTLANER---VAMATGTALGNPMEELLK------VLGDMELDVAQ
Rv3573c|M.tuberculosis_H37Rv        WRLARTTLANER---VAMATGTALGNPMEELLK------VLGDMELDVAQ
MMAR_5068|M.marinum_M               WRLARTTLANER---VAMATGTALGNPMEELLE------VLAELELDTGQ
MUL_4144|M.ulcerans_Agy99           WRLARTTLANER---VAMATGTALGNPMEELLE------VLAEPELDTGQ
MAV_0587|M.avium_104                WRLARTTLANER---VAMASGTALGNPMEELLE------LLSTLPLDSAQ
MAB_0580|M.abscessus_ATCC_1997      WRLARTTLANER---VAMAGGGTLDEAMESLLA------LIGDTELDAAQ
MLBr_00737|M.leprae_Br4923          FKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSI
                                    :: * :** : *    * * * : .     ::                . 

Mflv_1460|M.gilvum_PYR-GCK          QDRLGHLIGTAQVGTLLDQRIAQLAVEGQ-DPGPQASARKLIGVRYRQAL
Mvan_5311|M.vanbaalenii_PYR-1       QDQLGQLIVTAQVGSLLDQRIAQLAVEGQ-DPGPQASARKLIGVRYRQAL
MSMEG_6041|M.smegmatis_MC2_155      QDRLGALIVTAQVGSLLDQRIAQLAVSGQ-DTGAQASARKLIGVRYRQAL
TH_1744|M.thermoresistible__bu      QDRLGGLIVSAQVGSLLDQRIAQKAVGGQ-DPGAESSARKLIGVRHRQEL
Mb3604c|M.bovis_AF2122/97           QDRLGRLILLAQAGALLDRRIAELAVGGQ-DPGAQSSVRKLIGVRYRQAL
Rv3573c|M.tuberculosis_H37Rv        QDRLGRLILLAQAGALLDRRIAELAVGGQ-DPGAQSSVRKLIGVRYRQAL
MMAR_5068|M.marinum_M               QDRLARLIVATQTGALLDQRIAQLVMGGR-DPGAQSSVRKLIGVRYRQAL
MUL_4144|M.ulcerans_Agy99           QDRLARLIVATQTGALLDQRIAQLVMGGR-DPGAQSSVRKLIGVRYRQAL
MAV_0587|M.avium_104                QDRLGRLIVTAQTGALLDQRIAQLAVGGQ-DPGAQSSVRKLIGVRYRQAL
MAB_0580|M.abscessus_ATCC_1997      LDTLGAFVCSAQTGALLDLRTALRAIGGQ-DPGAASSVRKLVGVRHRQGL
MLBr_00737|M.leprae_Br4923          QFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEV
                                       *. :   .:.. *:    *  .  *. * *  ::. * ..      :

Mflv_1460|M.gilvum_PYR-GCK          AEFRMELSEGAGAIVNQQVHDFLN-TRCLTIAGGTEQILLTMAGERLLGL
Mvan_5311|M.vanbaalenii_PYR-1       AEFRMDLSDGAGAVENRQVHDFLN-TRCLTIAGGTEQILLTMAGERLLGL
MSMEG_6041|M.smegmatis_MC2_155      AEFHMELTEGGGAVRNREVHTFLN-TRCLTIAGGTEQILLTLAGERLLGL
TH_1744|M.thermoresistible__bu      SEFRMELSDGAGVVHNPTVHTFLN-ARCLTIAGGTEQILLTLAGERLLGL
Mb3604c|M.bovis_AF2122/97           AEYLMEVSDGGGLVENRAVYDFLN-TRCLTIAGGTEQILLTVAAERLLGL
Rv3573c|M.tuberculosis_H37Rv        AEYLMEVSDGGGLVENRAVYDFLN-TRCLTIAGGTEQILLTVAAERLLGL
MMAR_5068|M.marinum_M               AEYMMDVSAGGGLVENRAVFDFLN-TRCLTIAGGTEQILLTVAAERLLGL
MUL_4144|M.ulcerans_Agy99           AEYMMDVSACGGLVENRAVFDFLN-TRCLTIAGGTEQILLTVAAERLLGL
MAV_0587|M.avium_104                AEYTMDVSEGGGLVHNRAVYDFLN-TRCLTIAGGTEQILLTVAAERLLGL
MAB_0580|M.abscessus_ATCC_1997      SEHILDYVDTHGAVESREMWLFMR-DRCLSIAGGTTQILLSVAGERLLGL
MLBr_00737|M.leprae_Br4923          TTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
                                    :   ::     *   .  :  *:.  :   *  ** **   : .. **  

Mflv_1460|M.gilvum_PYR-GCK          PR
Mvan_5311|M.vanbaalenii_PYR-1       PR
MSMEG_6041|M.smegmatis_MC2_155      PR
TH_1744|M.thermoresistible__bu      PR
Mb3604c|M.bovis_AF2122/97           PR
Rv3573c|M.tuberculosis_H37Rv        PR
MMAR_5068|M.marinum_M               PR
MUL_4144|M.ulcerans_Agy99           PR
MAV_0587|M.avium_104                PR
MAB_0580|M.abscessus_ATCC_1997      PR
MLBr_00737|M.leprae_Br4923          --