For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSFLKTVPEELTAAAAQLGTIGSSMSAQNAAAAAPTTVIAPAALDEVSALQAALFTAYGTYYQQVSADAQ AMHDMFVNTLGASAGTYGATENLNSAAAASPLDGITSGISGFIQNAGSIIPDSWSSNIGNLTNIGVGNWA SASSTLIGLAGGGLLPAEEAAEADVSLGAEAGLGALSELGGAEAALGAPIAAGIGGASAVGMLSVPPTWA GSATLVSSTTPLAGAGWTAAAPTAAPGTFMGVPAGLGSAARNSAGFGAPRYGVKPIVMPKPAAV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4451 | - | - | 100% (274) | PE family protein, PE8 |
| M. marinum M | MMAR_1949 | - | 1e-82 | 62.01% (279) | PE family protein |
| M. marinum M | MMAR_2673 | - | 3e-28 | 65.31% (98) | PE family protein, PE19 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1069c | PE8 | 1e-114 | 77.82% (275) | PE family protein |
| M. gilvum PYR-GCK | Mflv_2152 | - | 5e-07 | 25.58% (215) | hypothetical protein Mflv_2152 |
| M. tuberculosis H37Rv | Rv1040c | PE8 | 1e-114 | 77.82% (275) | PE family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 40.22% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0664 | - | 1e-08 | 37.25% (102) | PE family protein |
| M. avium 104 | MAV_1346 | - | 5e-53 | 47.55% (286) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0618 | - | 2e-06 | 34.38% (96) | PE family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4620 | - | 1e-151 | 99.27% (274) | PE family protein |
| M. vanbaalenii PYR-1 | Mvan_0414 | - | 7e-07 | 32.98% (94) | PE domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4451|M.marinum_M -MSFLKTVPEELTAAAAQLGTIGSSMSAQNAAAAAPTTVIAPAALDEVSA
MUL_4620|M.ulcerans_Agy99 -MSFLKTVPEELTAAAAQLGTIGSSMSAQNAAAAAPTTVIAPAALDEVSA
Mb1069c|M.bovis_AF2122/97 -MSFLKTVPEELTAAAAQLGTIGAAMAAQNAAAAAPTTAIAPAALDEVSA
Rv1040c|M.tuberculosis_H37Rv -MSFLKTVPEELTAAAAQLGTIGAAMAAQNAAAAAPTTAIAPAALDEVSA
MSMEG_0618|M.smegmatis_MC2_155 -MT-LRVVPEGLTAASSAVEALTARLAAAHAAAAPMISTVLPPAADAVSL
Mvan_0414|M.vanbaalenii_PYR-1 -MT-LRVVPEGLTAAGAAVEALTARMAAAHAAAAPVVTAVLPPAADVVSL
MAB_0664|M.abscessus_ATCC_1997 -MS-LNVVPEGLTAASAAVEALTARLAAVNAAAAPVIGAVMPPAADPVSM
MLBr_01183|M.leprae_Br4923 MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
MAV_1346|M.avium_104 MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSIAPAAADEVSA
Mflv_2152|M.gilvum_PYR-GCK -----MHRTRKLFATTMFAAAGAVSAAVALSATATAQPAPAPAPAPEVPG
.. * *. . :*:* *.. *.
MMAR_4451|M.marinum_M LQAALFTAYGTYYQQVSADAQAMHDMFVNTLGASAGTYGATENLNSAAAA
MUL_4620|M.ulcerans_Agy99 LQAALFTAYGTYYQQVSADAQAMHDMFVNTLGASAGTYGATENLNSAAAA
Mb1069c|M.bovis_AF2122/97 LQAALFTAYGTFYQQVSAEAQAMHDMFVNTLGISAGTYGVTESLNSSAAA
Rv1040c|M.tuberculosis_H37Rv LQAALFTAYGTFYQQVSAEAQAMHDMFVNTLGISAGTYGVTESLNSSAAA
MSMEG_0618|M.smegmatis_MC2_155 QTAAGFSANGAQQSAVAAQG-------VEELGRSG--VGVGE-----SGV
Mvan_0414|M.vanbaalenii_PYR-1 QAATGFSARAAEHQSVAAQG-------VEELGRSG--IAVGE-----SAA
MAB_0664|M.abscessus_ATCC_1997 QSAALFSAHGLERTGAGARA-------AYELGRSG--VGATE-----AAA
MLBr_01183|M.leprae_Br4923 LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN-----
MAV_1346|M.avium_104 LQAAQFSAYGTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANRVNTS
Mflv_2152|M.gilvum_PYR-GCK LPFLQQLAANPAAATQLMQG------FANLMGTAPAAPAATATAVPATPV
. . : .
MMAR_4451|M.marinum_M SPLDGITSGISGFIQNAGSIIPDSWSSNIGNLTNIGVGNWASASSTLIGL
MUL_4620|M.ulcerans_Agy99 SPLDGITSGISGFIQNTGSIIPDSWSNNIGNLTNIGVGNWASASSTLIGL
Mb1069c|M.bovis_AF2122/97 SPLSGITGEASAIIQATTGLFPPELSGGIGNILNIGAGNWASATSTLIGL
Rv1040c|M.tuberculosis_H37Rv SPLSGITGEASAIIQATTGLFPPELSGGIGNILNIGAGNWASATSTLIGL
MSMEG_0618|M.smegmatis_MC2_155 S---------------------------------YATGDAQAAASYLTAR
Mvan_0414|M.vanbaalenii_PYR-1 S---------------------------------YAGGDAMAASSYLIAR
MAB_0664|M.abscessus_ATCC_1997 S---------------------------------YTVGDIQAAATYLPGI
MLBr_01183|M.leprae_Br4923 -------------------------HDSL---------------------
MAV_1346|M.avium_104 AAALQGLAPNVIPNAAPAADPPPAGTTSLGTSIGWAQNVGAAASDFITLG
Mflv_2152|M.gilvum_PYR-GCK T----------------------------------GPGATASITLPQPAN
MMAR_4451|M.marinum_M AGGGLLPAEEAAEADVSLGAEAGLGALSELGGAEAALGAP-IAAGIGGAS
MUL_4620|M.ulcerans_Agy99 AGGGLLPAEEAAEADVSLGAEAGLGALSELGGAEAALGAP-IAAGIGGAS
Mb1069c|M.bovis_AF2122/97 AGGGLLPAEEAAEAASALGGEAALGELGALGAAEAALGEAGIAAGLGSAS
Rv1040c|M.tuberculosis_H37Rv AGGGLLPAEEAAEAASALGGEAALGELGALGAAEAALGEAGIAAGLGSAS
MSMEG_0618|M.smegmatis_MC2_155 GL------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 G-------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 A-------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 EGQFAPVPGAAGIPNFNPGLTAATTAGPPAPAAPAAAAGAPVLASMGRGP
Mflv_2152|M.gilvum_PYR-GCK VLPGATALGNGNVTTVPAGNTTTVPQTAPAAPASPLTGLTDQLGMPGGLA
MMAR_4451|M.marinum_M AVGMLSVPPTWAG---SATLVSSTTPLAGAGWTAAAPTAAPGTFMG-VPA
MUL_4620|M.ulcerans_Agy99 AVGMLSVPPTWAG---SATLVSSTTPLAGAGWTAAAPTAAPGTFMG-VPA
Mb1069c|M.bovis_AF2122/97 AIGMLSVPPAWAG---QATLVSTTSTLPGAGWTAAAPQAAAGTFIP-GMP
Rv1040c|M.tuberculosis_H37Rv AIGMLSVPPAWAG---QATLVSTTSTLPGAGWTAAAPQAAAGTFIP-GMP
MSMEG_0618|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0664|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 SIGGLSVPPSWAPGGVAPAANATPAQLVGAGFTSAAPDTAPVTAVPGGVP
Mflv_2152|M.gilvum_PYR-GCK SLLPAGNP--------------LAGLLPGAATTAPATTVAPAAVAPAAAP
MMAR_4451|M.marinum_M GLGSAARNSAGFGAPRYGVKPIVMPKPAAV
MUL_4620|M.ulcerans_Agy99 GLGSAARNSAGFGAPRYGVKPIVMPKPAAV
Mb1069c|M.bovis_AF2122/97 GVASAARNSAGFGAPRYGVKPIVMPKPATV
Rv1040c|M.tuberculosis_H37Rv GVASAARNSAGFGAPRYGVKPIVMPKPATV
MSMEG_0618|M.smegmatis_MC2_155 ------------------------------
Mvan_0414|M.vanbaalenii_PYR-1 ------------------------------
MAB_0664|M.abscessus_ATCC_1997 ------------------------------
MLBr_01183|M.leprae_Br4923 ------------------------------
MAV_1346|M.avium_104 SMATAGRGGYGLGAPRYGVKPTVMPKPAI-
Mflv_2152|M.gilvum_PYR-GCK AVPSMLSPLAALP-----------------