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MGGIVYEAVSTTLADKHLERVTAIAVEAGKLTLKYRQNPEVTEKGDHGDDTSPVTEADLAANSYITNHLA ALDPDIPIISEETKSADYETRQHWQRFWLVDPLDGTKEFIKGSDEFTVNIALIENQEPILGAIYVPAKQL LYYAAKGHGSWRVKDNGTPVQIFSSVPDLSNGLTIVESRSHPSAALENYLKDFPIRKRISAGSSLKFCVV AEGIADIYPRLNPTMEWDVAAGDCIYRNSTHSGQRTSSLTYNKPTLKNDSFVIGLK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4258 | - | - | 100% (266) | monophosphatase CysQ-like protein |
| M. marinum M | MMAR_3456 | cysQ_1 | 7e-17 | 31.60% (250) | monophosphatase CysQ_1 |
| M. marinum M | MMAR_1511 | - | 1e-16 | 28.87% (239) | monophosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3161 | - | 1e-18 | 32.69% (208) | monophosphatase |
| M. gilvum PYR-GCK | Mflv_4454 | - | 2e-14 | 28.02% (232) | histidinol-phosphate phosphatase, putative |
| M. tuberculosis H37Rv | Rv3137 | - | 2e-18 | 32.69% (208) | monophosphatase |
| M. leprae Br4923 | MLBr_00662 | - | 4e-17 | 31.31% (198) | putative monophosphatase |
| M. abscessus ATCC 19977 | MAB_3485 | - | 1e-12 | 29.50% (200) | monophosphatase |
| M. avium 104 | MAV_2129 | - | 2e-17 | 30.56% (252) | 3'(2'),5'-bisphosphate nucleotidase, putative |
| M. smegmatis MC2 155 | MSMEG_2083 | - | 1e-15 | 28.45% (232) | inositol monophosphatase |
| M. thermoresistible (build 8) | TH_2149 | - | 9e-19 | 33.00% (203) | PROBABLE MONOPHOSPHATASE |
| M. ulcerans Agy99 | MUL_2730 | cysQ_1 | 4e-17 | 30.77% (247) | monophosphatase CysQ_1 |
| M. vanbaalenii PYR-1 | Mvan_1908 | - | 7e-15 | 29.18% (233) | histidinol-phosphate phosphatase, putative |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4454|M.gilvum_PYR-GCK --MS--------TLADDVTLALQLADEADVLTMQRFG--AVDLRVETKPD
Mvan_1908|M.vanbaalenii_PYR-1 --MS--------TLVDDLNLALRLADEADALTMQRFG--AVDLRVETKPD
MSMEG_2083|M.smegmatis_MC2_155 --MS--------TVADDLTLALELADQADALTMDRFG--ALDLRVETKPD
MAB_3485|M.abscessus_ATCC_1997 --MTPT-----VSLREDRRLALELADAADEITTSRFG--ALDLRVDTKPD
TH_2149|M.thermoresistible__bu --MTAVPDDAPDIRDDDLALALLLADQADVVTRDRFG--SLDLHVETKPD
Mb3161|M.bovis_AF2122/97 ------------MSHDDLMLALALADRADELTRVRFG--ALDLRIDTKPD
Rv3137|M.tuberculosis_H37Rv ------------MSHDDLMLALALADRADELTRVRFG--ALDLRIDTKPD
MLBr_00662|M.leprae_Br4923 ------------------MLALTLADRADALTSARFG--ALNLRVDTKPD
MAV_2129|M.avium_104 --------------MNDHELAARLATEAGRLLLG------VRDEFADAPA
MUL_2730|M.ulcerans_Agy99 --------------MNDHAVAAWLATEAGRLLLG------VREEFAAAEG
MMAR_4258|M.marinum_M MGGIVYEAVSTTLADKHLERVTAIAVEAGKLTLKYRQNPEVTEKGDHGDD
. :* *. : : .
Mflv_4454|M.gilvum_PYR-GCK LTPATDADLDAERLLRARLGEARPQDSVFGEE--FGG--TKEFTGRQWVV
Mvan_1908|M.vanbaalenii_PYR-1 MTPATDADLDAEKLLRARLTESRPQDSVFGEE--FGG--TREFTGRQWVV
MSMEG_2083|M.smegmatis_MC2_155 LTPVTDADRGAEETLRAALAQARPADTVFGEE--FGG--TTASTGRQWVI
MAB_3485|M.abscessus_ATCC_1997 LTPVTDADTSVETVLRSLLHRSRPADSVLGEE--YGG--EATFTGRQWVI
TH_2149|M.thermoresistible__bu LTPVSDADRSVERILRGTLAQQRPDDPILGEE--FGG--ATVFSGRQWII
Mb3161|M.bovis_AF2122/97 LTPVTDADRAVESDVRQTLGRDRPGDGVLGEE--FGG--STTFTGRQWIV
Rv3137|M.tuberculosis_H37Rv LTPVTDADRAVESDVRQTLGRDRPGDGVLGEE--FGG--STTFTGRQWIV
MLBr_00662|M.leprae_Br4923 LTPVTDADRAVEADVRAVLGRERPKDGILGEE--YGG--TITFSGQQWIV
MAV_2129|M.avium_104 SERKAAGDKRSHDFLIEALAAERPGDAVLSEE--GADDPVRLRSERVWIV
MUL_2730|M.ulcerans_Agy99 AQRKAAGDKRSHDFLMDKLAAERPGDAVLSEE--GADDPVRLRSERVWIV
MMAR_4258|M.marinum_M TSPVTEADLAANSYITNHLAALDPDIPIISEETKSADYETRQHWQRFWLV
: .* . : * * ::.** .. : *::
Mflv_4454|M.gilvum_PYR-GCK DPIDGTKNFVR-GVPVWSTLIALLVDGVPVVGVVSAPALGRRWWAGQGQG
Mvan_1908|M.vanbaalenii_PYR-1 DPIDGTKNFVR-GVPVWSTLIALLVDGVPVVGVISAPALGRRWWAGEGQG
MSMEG_2083|M.smegmatis_MC2_155 DPIDGTKNFVR-GVPVWCTLIALLDDGVPRVGVVSAPALARRWWAAEGQG
MAB_3485|M.abscessus_ATCC_1997 DPIDGTKNFAR-GVPIWATLIALLQDGVPVVGVVSAPALSRRWWAAEGLG
TH_2149|M.thermoresistible__bu DPIDGTKNFVR-GVPVWATLIALLQDGVPTVGVVSAPALQRRWYAAAGQG
Mb3161|M.bovis_AF2122/97 DPIDGTKNFVR-GVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRG
Rv3137|M.tuberculosis_H37Rv DPIDGTKNFVR-GVPVWASLIALLEDGVPSVGVVSAPALQRRWWAARGRG
MLBr_00662|M.leprae_Br4923 DPIDGTKNFVR-GVPVWASLIALLEDGVPSIGVVSAPALQRRWWAARGQG
MAV_2129|M.avium_104 DPLDGTREFSELGRDDWAVHVALWEAGELVAGAVALPAQGVTFATPEVAS
MUL_2730|M.ulcerans_Agy99 DPLDGTREFSELGRVDWAVHVALWQAGQLVAGAVALPAQDITLATPHVEP
MMAR_4258|M.marinum_M DPLDGTKEFIK-GSDEFTVNIALIENQEPILGAIYVPAKQLLYYAAKGHG
**:***::* . * : :** *.: ** :
Mflv_4454|M.gilvum_PYR-GCK AFTSFAG-TTRRISVSGVGDLASASLSYSDLTTGWDD--KRARFVELLDA
Mvan_1908|M.vanbaalenii_PYR-1 AFTSFGG-DTRRISVSAVADMEAASLSFSDLATGWEE--KRSRFVELLDA
MSMEG_2083|M.smegmatis_MC2_155 AFGSFNG-TTRKLSVSGVSDLSAASLSYSDLTTGWDD--RRERFVELTDA
MAB_3485|M.abscessus_ATCC_1997 AHSRVGSEEERSIHVSAVDQLSSASLSFSSLS-GWADRGKRDRFIDLTDE
TH_2149|M.thermoresistible__bu AHVVVGDDVPRRISVSSVSDLESASLSFSSLS-GWAVRKLRDRFIDLTDT
Mb3161|M.bovis_AF2122/97 AFASVDGARPHRLSVSSVAELHSASLSFSSLS-GWARLGLRERFIGLTDT
Rv3137|M.tuberculosis_H37Rv AFASVDGARPHRLSVSSVAELHSASLSFSSLS-GWARPGLRERFIGLTDT
MLBr_00662|M.leprae_Br4923 AFVAVDGV-PRRLAVSEVADLNSASLSFSSLS-GWAQRGLRDRFLELTDA
MAV_2129|M.avium_104 PPVAPGK---PRIVVSRTRPPAIALNVRDALD---------GVLVEMGSA
MUL_2730|M.ulcerans_Agy99 PPAAPDR---PRIVVSRTRPPAIALAVRDALD---------GTLVEMGSA
MMAR_4258|M.marinum_M SWRVKDN-GTPVQIFSSVPDLSNGLTIVESRS--HPSAALENYLKDFP--
. .* . . . : :
Mflv_4454|M.gilvum_PYR-GCK VWRVRGYGDFWSYCLVAEG-AVDIAVEPEVKLWDLAPLDVLVREAGGRFT
Mvan_1908|M.vanbaalenii_PYR-1 VWRMRGYGDFWSYCLVAEG-AVDIAVEPEVKLWDLAPLDILVREAGGRFT
MSMEG_2083|M.smegmatis_MC2_155 VWRVRAYGDFWSYCMVAEG-AVDIACEPEVKLWDIAPLDVLIREAGGTFT
MAB_3485|M.abscessus_ATCC_1997 IWRVRGFGDFFSYCLVAEG-AVDIAAEPEVSLWDLAPLDILVREAGGRFT
TH_2149|M.thermoresistible__bu VWRVRGFGDFFSYCLLAEG-AVDIATEPEVSLWDLAALDILVREAGGTFT
Mb3161|M.bovis_AF2122/97 VWRVRAYGDFLSYCLVAEG-AVDIAAEPQVSVWDLAALDIVVREAGGRLT
Rv3137|M.tuberculosis_H37Rv VWRVRAYGDFLSYCLVAEG-AVDIAAEPQVSVWDLAALDIVVREAGGRLT
MLBr_00662|M.leprae_Br4923 VWRVRAYGDFLSYCLLAEG-AIDVAAEPKVSVWDLAALDIVVREAGGVLT
MAV_2129|M.avium_104 GAKVASVVQGLSDVYVHAGGQFEWDSAAPVAVARAAGLHTSRIDGS---A
MUL_2730|M.ulcerans_Agy99 GAKVASVVQGLADVYVHAGGQFEWDSAAPVAVARSAGLHTSRIDGS---A
MMAR_4258|M.marinum_M IRKRISAGSSLKFCVVAEGIADIYPRLNPTMEWDVAAGDCIYRNST----
: . . : * . * . :.
Mflv_4454|M.gilvum_PYR-GCK DLSGGAGPHGGSAVATNGRVHDAVLAALDV---
Mvan_1908|M.vanbaalenii_PYR-1 NLAGEPGPHGGSAVATNGLLHDAVLSALAD---
MSMEG_2083|M.smegmatis_MC2_155 SIDGADGPHGGSALATNGVLHDAVVSRLAVR--
MAB_3485|M.abscessus_ATCC_1997 NLAGEPGPHGGSAVATNGLLHEEVLKALS----
TH_2149|M.thermoresistible__bu NLEGAPGPHGGSAVATNGRLHNAVLAHLRGV--
Mb3161|M.bovis_AF2122/97 SLDGVAGPHGGSAVATNGLLHDEVLTRLNAG--
Rv3137|M.tuberculosis_H37Rv SLDGVAGPHGGSAVATNGLLHDEVLTRLNAG--
MLBr_00662|M.leprae_Br4923 GLDGTPGPHGGSAVATNGRLHQEVLTRIGATVK
MAV_2129|M.avium_104 LAYNQPDPKLPDLVVCRPELADAVLAVTR----
MUL_2730|M.ulcerans_Agy99 LTYNRPDPKLPDLVVCRPELATAVLAATG----
MMAR_4258|M.marinum_M ----HSGQRTSSLTYNKPTLKNDSFVIGLK---
. : . . : .