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AERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDV ARITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRAKVALPGGDAIGSRPLDMHQAGLRQLGAQCNIE HGCVVAQADTLRGAEIQLEFPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQIEGAGS PTMTITGVPRLHPTEHRVIGDRIVAATWGIAAAMTRGDITVTGIDPSHLQLVLHKLYDAGATVTQTDDSF RIVQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSMITENVFEARFRFVEEMIRLGADARTDGHH AVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPLFVEYLGILGAEIERVQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4083 | murA | - | 100% (417) | UDP-N-acetylglucosamine 1- carboxyvinyltransferase MurA |
| M. marinum M | MMAR_1320 | aroA | 2e-08 | 23.04% (421) | 3-phosphoshikimate 1-carboxyvinyltransferase AroA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1348 | murA | 0.0 | 95.91% (416) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
| M. gilvum PYR-GCK | Mflv_2322 | - | 0.0 | 91.59% (416) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
| M. tuberculosis H37Rv | Rv1315 | murA | 0.0 | 95.91% (416) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
| M. leprae Br4923 | MLBr_01150 | murA | 0.0 | 94.95% (416) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
| M. abscessus ATCC 19977 | MAB_1457 | - | 0.0 | 88.32% (411) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
| M. avium 104 | MAV_1531 | murA | 0.0 | 96.64% (417) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
| M. smegmatis MC2 155 | MSMEG_4932 | murA | 0.0 | 91.83% (416) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
| M. thermoresistible (build 8) | TH_1554 | - | 0.0 | 92.31% (416) | PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA |
| M. ulcerans Agy99 | MUL_3950 | murA | 0.0 | 99.76% (417) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4324 | - | 0.0 | 92.79% (416) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2322|M.gilvum_PYR-GCK ----------------------------MSERFVVTGGCRLSGEVAVGGA
Mvan_4324|M.vanbaalenii_PYR-1 ----------------------------MSERFVVTGGGRLSGEVAVGGA
MMAR_4083|M.marinum_M ----------------------------MAERFVVTGGNRLSGEVAVGGA
MUL_3950|M.ulcerans_Agy99 ----------------------------MAERFVVTGGNRLSGEVAVGGA
Mb1348|M.bovis_AF2122/97 ----------------------------MAERFVVTGGNRLSGEVAVGGA
Rv1315|M.tuberculosis_H37Rv ----------------------------MAERFVVTGGNRLSGEVAVGGA
MLBr_01150|M.leprae_Br4923 ----------------------------MAERFVVTGGNRLSGEVTVGGA
MAV_1531|M.avium_104 ----------------------------MAERFVVTGGNRLSGEVAVGGA
MSMEG_4932|M.smegmatis_MC2_155 ----------------------------MSERFVVTGGNRLSGEVAVGGA
TH_1554|M.thermoresistible__bu MGKPYRLRPGRRPERKLTPAPAADYTDRVSERFVVTGGNRLSGEVAVGGA
MAB_1457|M.abscessus_ATCC_1997 ---------------------------------MVTGGARLTGNVAVTGA
:**** **:*:*:* **
Mflv_2322|M.gilvum_PYR-GCK KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELEGDVV
Mvan_4324|M.vanbaalenii_PYR-1 KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVV
MMAR_4083|M.marinum_M KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
MUL_3950|M.ulcerans_Agy99 KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
Mb1348|M.bovis_AF2122/97 KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
Rv1315|M.tuberculosis_H37Rv KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
MLBr_01150|M.leprae_Br4923 KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELYGDVA
MAV_1531|M.avium_104 KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
MSMEG_4932|M.smegmatis_MC2_155 KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGATV
TH_1554|M.thermoresistible__bu KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGETV
MAB_1457|M.abscessus_ATCC_1997 KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELEGDVV
**********:********************************** * ..
Mflv_2322|M.gilvum_PYR-GCK RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKKARVALPGGDAIGSR
Mvan_4324|M.vanbaalenii_PYR-1 RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKKAKVALPGGDAIGSR
MMAR_4083|M.marinum_M RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRAKVALPGGDAIGSR
MUL_3950|M.ulcerans_Agy99 RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRAKVALPGGDAIGSR
Mb1348|M.bovis_AF2122/97 RITAPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSR
Rv1315|M.tuberculosis_H37Rv RITAPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSR
MLBr_01150|M.leprae_Br4923 RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKQARVALPGGDAIGSR
MAV_1531|M.avium_104 RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSR
MSMEG_4932|M.smegmatis_MC2_155 RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKKARVALPGGDAIGSR
TH_1554|M.thermoresistible__bu RITSPDELKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSR
MAB_1457|M.abscessus_ATCC_1997 RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCRRAKVALPGGDAIGSR
***:*** **************************::*:************
Mflv_2322|M.gilvum_PYR-GCK PLDMHQAGLRQLGARCNIEHGCVVAEADHLHGAEIQLEFPSVGATENILM
Mvan_4324|M.vanbaalenii_PYR-1 PLDMHQAGLRQLGARCNIEHGCVVAEADHLRGAEIQLEFPSVGATENILM
MMAR_4083|M.marinum_M PLDMHQAGLRQLGAQCNIEHGCVVAQADTLRGAEIQLEFPSVGATENILM
MUL_3950|M.ulcerans_Agy99 PLDMHQAGLRQLGAQCNIEHGCVVAQADTLRGAEIQLEFPSVGATENILM
Mb1348|M.bovis_AF2122/97 PLDMHQAGLRQLGAHCNIEHGCVVARAETLRGAEIQLEFPSVGATENILM
Rv1315|M.tuberculosis_H37Rv PLDMHQAGLRQLGAHCNIEHGCVVARAETLRGAEIQLEFPSVGATENILM
MLBr_01150|M.leprae_Br4923 PLDMHQAGLRQLGARCNIEHGCVVASAETLRGAEIQLEFPSVGATENILM
MAV_1531|M.avium_104 PLDMHQAGLRQLGATCNIEHGCVVAQADTLRGAEIQLEFPSVGATENILM
MSMEG_4932|M.smegmatis_MC2_155 PLDMHQAGLRQLGATCNIEHGCVVAEADHLHGAEIQLEFPSVGATENILM
TH_1554|M.thermoresistible__bu PLDMHQAGLRQLGARCNIEHGCVVAEADHLRGAEIQLEFPSVGATENILM
MAB_1457|M.abscessus_ATCC_1997 PLDMHQAGLRQLGAECTIEHGCVVAEAKALHGADIHLEFPSVGATENILM
************** *.******** *. *:**:*:**************
Mflv_2322|M.gilvum_PYR-GCK AAVLADGVTTIHNAAREPDVVDLCTMLNQMGAQVTGAGSSTLTIIGVDRL
Mvan_4324|M.vanbaalenii_PYR-1 AAVLAEGVTTIHNAAREPDVVDLCTMLNQMGAQVTGAGSSTLTITGVDRL
MMAR_4083|M.marinum_M AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQIEGAGSPTMTITGVPRL
MUL_3950|M.ulcerans_Agy99 AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQIEGAGSPTMTITGVPRL
Mb1348|M.bovis_AF2122/97 AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRL
Rv1315|M.tuberculosis_H37Rv AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRL
MLBr_01150|M.leprae_Br4923 AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGVGSPTMTITGVPRL
MAV_1531|M.avium_104 AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRL
MSMEG_4932|M.smegmatis_MC2_155 AAVVAEGVTTIHNAAREPDVVDLCAMLNEMGAQISGAGTSTLTITGVDRL
TH_1554|M.thermoresistible__bu AAVLAEGTTTIHNAAREPDVVDLCTMLNEMGAQISGAGTPTMTITGVDRL
MAB_1457|M.abscessus_ATCC_1997 AAVLADGVTTIHNAAREPDVVDLCTMLVQMGAEIEGAGTSTLTVTGVSAL
***:*:*.****************:** :***:: *.*:.*:*: ** *
Mflv_2322|M.gilvum_PYR-GCK HPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPAHLQLVLHKLHDAGA
Mvan_4324|M.vanbaalenii_PYR-1 YPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPAHLQLVLHKLHDAGA
MMAR_4083|M.marinum_M HPTEHRVIGDRIVAATWGIAAAMTRGDITVTGIDPSHLQLVLHKLYDAGA
MUL_3950|M.ulcerans_Agy99 HPTEHRVIGDRIVAATWGIAAAMTRGDITVTGIDPSHLQLVLHKLYDAGA
Mb1348|M.bovis_AF2122/97 HPTEHRVIGDRIVAATWGIAAAMTRGDISVAGVDPAHLQLVLHKLHDAGA
Rv1315|M.tuberculosis_H37Rv HPTEHRVIGDRIVAATWGIAAAMTRGDISVAGVDPAHLQLVLHKLHDAGA
MLBr_01150|M.leprae_Br4923 YPTEHRVIGDRIVAATWGIAAAMTRGDIAVTGVDPAHLQLVLHKLHDAGA
MAV_1531|M.avium_104 YPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPAHLQVVLHKLHDAGA
MSMEG_4932|M.smegmatis_MC2_155 YPTEHRVIGDRIVAATWGIAAAMTRGDITVTGVDPQHLQLVLHKLHDAGA
TH_1554|M.thermoresistible__bu YPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPQHLQLVLHKLHDAGA
MAB_1457|M.abscessus_ATCC_1997 HPTEHRVIGDRIVAATWGLAAAMTRGDVTVTGVDPEHLQLVLHKLHDAGA
:*****************:********::*:*:** ***:*****:****
Mflv_2322|M.gilvum_PYR-GCK TVTQSDDGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIGLAAVADGTSM
Mvan_4324|M.vanbaalenii_PYR-1 TVTQTDDGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIGLAAVADGTSM
MMAR_4083|M.marinum_M TVTQTDDSFRIVQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
MUL_3950|M.ulcerans_Agy99 TVTQTDDSFRIVQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
Mb1348|M.bovis_AF2122/97 TVTQTDASFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
Rv1315|M.tuberculosis_H37Rv TVTQTDASFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
MLBr_01150|M.leprae_Br4923 TVTQTDDSFRVAQYERPKAVNVATLPFPGFPTDLQPMAIALTSIADGTSM
MAV_1531|M.avium_104 TVTQTDDSFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
MSMEG_4932|M.smegmatis_MC2_155 TVTQNDNGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIGLAAIADGTSM
TH_1554|M.thermoresistible__bu TVTQHDNGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
MAB_1457|M.abscessus_ATCC_1997 TVTQSDDGFRVVQYERPKAINVATLPFPGFPTDLQPMAIGLAAIADGTSM
**** * .**:.*******:*******************.*:::******
Mflv_2322|M.gilvum_PYR-GCK ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQLSSAPVWSSDIRA
Mvan_4324|M.vanbaalenii_PYR-1 ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQLSSAPVWSSDIRA
MMAR_4083|M.marinum_M ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
MUL_3950|M.ulcerans_Agy99 ITENVFEARFRFVEEMIRLGADALTDGHHAVVRGLPQLSSAPVWCSDIRA
Mb1348|M.bovis_AF2122/97 ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
Rv1315|M.tuberculosis_H37Rv ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
MLBr_01150|M.leprae_Br4923 ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
MAV_1531|M.avium_104 ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
MSMEG_4932|M.smegmatis_MC2_155 ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQLSSAPVWSSDIRA
TH_1554|M.thermoresistible__bu ITENVFEARFRFVEEMVRLGADARTDGHHAVVRGLPQLSSAPVWSSDIRA
MAB_1457|M.abscessus_ATCC_1997 ITENVFEARFRFVEEMMRLGADARTDGHHAVVRGIRQLSSAPVWSSDIRA
****************:****** **********: ********.*****
Mflv_2322|M.gilvum_PYR-GCK GAGLVLAGLVADGDTEVHDVFHIDRGYPKFVENLAALGAEIERVT-
Mvan_4324|M.vanbaalenii_PYR-1 GAGLVLAGLVADGDTEVHDVFHIDRGYPKFVENLVSLGAEIERVN-
MMAR_4083|M.marinum_M GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVEYLGILGAEIERVQ-
MUL_3950|M.ulcerans_Agy99 GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVEYLGILGAEIERVQ-
Mb1348|M.bovis_AF2122/97 GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLVSLGAEIERVCC
Rv1315|M.tuberculosis_H37Rv GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLVSLGAEIERVCC
MLBr_01150|M.leprae_Br4923 GAGLVLAGLVADGDTEVYDVFHIDRGYPLFVENLANLGAEIERVCL
MAV_1531|M.avium_104 GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLAILGAEIERVE-
MSMEG_4932|M.smegmatis_MC2_155 GAGLVLAGLVADGETEVHDVFHIDRGYPLFVENLVSLGAEIERVSS
TH_1554|M.thermoresistible__bu GAGLVLAGLVADGDTEVHDVFHIDRGYPRFVENLKSLGAEIERIS-
MAB_1457|M.abscessus_ATCC_1997 GAGLVLAGLVADGVTEVYDVFHIDRGYPLFVENLQSLGAEVERVS-
************* ***:********** *** * ****:**: