For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_1531 (murA)

annotation: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
coordinates: 1485921 - 1487174
length: 417

VAERFVVTGGNRLSGEVAVGGAKNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGD
VARITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSRPLDMHQAGLRQLGATCNI
EHGCVVAQADTLRGAEIQLEFPSVGATENILMAAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAG
SPTMTITGVPRLYPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPAHLQVVLHKLHDAGATVTQTDDS
FRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSMITENVFEARFRFVEEMIRLGADARTDGH
HAVVRGLPQLSSAPVWCSDIRAGAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLAILGAEIERVE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1531murA-100% (417)UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1348murA0.097.60% (416) UDP-N-acetylglucosamine 1-carboxyvinyltransferase
M. gilvum PYR-GCKMflv_2322-0.093.03% (416) UDP-N-acetylglucosamine 1-carboxyvinyltransferase
M. tuberculosis H37RvRv1315murA0.097.60% (416) UDP-N-acetylglucosamine 1-carboxyvinyltransferase
M. leprae Br4923MLBr_01150murA0.096.88% (416) UDP-N-acetylglucosamine 1-carboxyvinyltransferase
M. abscessus ATCC 19977MAB_1457-0.087.83% (411) UDP-N-acetylglucosamine 1-carboxyvinyltransferase
M. marinum MMMAR_4083murA0.096.64% (417) UDP-N-acetylglucosamine 1- carboxyvinyltransferase MurA
M. smegmatis MC2 155MSMEG_4932murA0.092.55% (416) UDP-N-acetylglucosamine 1-carboxyvinyltransferase
M. thermoresistible (build 8)TH_1554-0.093.27% (416) PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA
M. ulcerans Agy99MUL_3950murA0.096.40% (417) UDP-N-acetylglucosamine 1-carboxyvinyltransferase
M. vanbaalenii PYR-1Mvan_4324-0.093.99% (416) UDP-N-acetylglucosamine 1-carboxyvinyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2322|M.gilvum_PYR-GCK          ----------------------------MSERFVVTGGCRLSGEVAVGGA
Mvan_4324|M.vanbaalenii_PYR-1       ----------------------------MSERFVVTGGGRLSGEVAVGGA
Mb1348|M.bovis_AF2122/97            ----------------------------MAERFVVTGGNRLSGEVAVGGA
Rv1315|M.tuberculosis_H37Rv         ----------------------------MAERFVVTGGNRLSGEVAVGGA
MLBr_01150|M.leprae_Br4923          ----------------------------MAERFVVTGGNRLSGEVTVGGA
MAV_1531|M.avium_104                ----------------------------MAERFVVTGGNRLSGEVAVGGA
MMAR_4083|M.marinum_M               ----------------------------MAERFVVTGGNRLSGEVAVGGA
MUL_3950|M.ulcerans_Agy99           ----------------------------MAERFVVTGGNRLSGEVAVGGA
MSMEG_4932|M.smegmatis_MC2_155      ----------------------------MSERFVVTGGNRLSGEVAVGGA
TH_1554|M.thermoresistible__bu      MGKPYRLRPGRRPERKLTPAPAADYTDRVSERFVVTGGNRLSGEVAVGGA
MAB_1457|M.abscessus_ATCC_1997      ---------------------------------MVTGGARLTGNVAVTGA
                                                                     :**** **:*:*:* **

Mflv_2322|M.gilvum_PYR-GCK          KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELEGDVV
Mvan_4324|M.vanbaalenii_PYR-1       KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVV
Mb1348|M.bovis_AF2122/97            KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
Rv1315|M.tuberculosis_H37Rv         KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
MLBr_01150|M.leprae_Br4923          KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELYGDVA
MAV_1531|M.avium_104                KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
MMAR_4083|M.marinum_M               KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
MUL_3950|M.ulcerans_Agy99           KNSVLKLMAATLLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGDVA
MSMEG_4932|M.smegmatis_MC2_155      KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGATV
TH_1554|M.thermoresistible__bu      KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELDGETV
MAB_1457|M.abscessus_ATCC_1997      KNSVLKLMAAALLAEGTSTITNCPDILDVPLMAEVLRGLGATVELEGDVV
                                    **********:********************************** * ..

Mflv_2322|M.gilvum_PYR-GCK          RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKKARVALPGGDAIGSR
Mvan_4324|M.vanbaalenii_PYR-1       RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKKAKVALPGGDAIGSR
Mb1348|M.bovis_AF2122/97            RITAPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSR
Rv1315|M.tuberculosis_H37Rv         RITAPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSR
MLBr_01150|M.leprae_Br4923          RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKQARVALPGGDAIGSR
MAV_1531|M.avium_104                RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSR
MMAR_4083|M.marinum_M               RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRAKVALPGGDAIGSR
MUL_3950|M.ulcerans_Agy99           RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKRAKVALPGGDAIGSR
MSMEG_4932|M.smegmatis_MC2_155      RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCKKARVALPGGDAIGSR
TH_1554|M.thermoresistible__bu      RITSPDELKYDADFAAVRQFRASVCVLGPLVGRCKRARVALPGGDAIGSR
MAB_1457|M.abscessus_ATCC_1997      RITSPDEPKYDADFAAVRQFRASVCVLGPLVGRCRRAKVALPGGDAIGSR
                                    ***:*** **************************::*:************

Mflv_2322|M.gilvum_PYR-GCK          PLDMHQAGLRQLGARCNIEHGCVVAEADHLHGAEIQLEFPSVGATENILM
Mvan_4324|M.vanbaalenii_PYR-1       PLDMHQAGLRQLGARCNIEHGCVVAEADHLRGAEIQLEFPSVGATENILM
Mb1348|M.bovis_AF2122/97            PLDMHQAGLRQLGAHCNIEHGCVVARAETLRGAEIQLEFPSVGATENILM
Rv1315|M.tuberculosis_H37Rv         PLDMHQAGLRQLGAHCNIEHGCVVARAETLRGAEIQLEFPSVGATENILM
MLBr_01150|M.leprae_Br4923          PLDMHQAGLRQLGARCNIEHGCVVASAETLRGAEIQLEFPSVGATENILM
MAV_1531|M.avium_104                PLDMHQAGLRQLGATCNIEHGCVVAQADTLRGAEIQLEFPSVGATENILM
MMAR_4083|M.marinum_M               PLDMHQAGLRQLGAQCNIEHGCVVAQADTLRGAEIQLEFPSVGATENILM
MUL_3950|M.ulcerans_Agy99           PLDMHQAGLRQLGAQCNIEHGCVVAQADTLRGAEIQLEFPSVGATENILM
MSMEG_4932|M.smegmatis_MC2_155      PLDMHQAGLRQLGATCNIEHGCVVAEADHLHGAEIQLEFPSVGATENILM
TH_1554|M.thermoresistible__bu      PLDMHQAGLRQLGARCNIEHGCVVAEADHLRGAEIQLEFPSVGATENILM
MAB_1457|M.abscessus_ATCC_1997      PLDMHQAGLRQLGAECTIEHGCVVAEAKALHGADIHLEFPSVGATENILM
                                    ************** *.******** *. *:**:*:**************

Mflv_2322|M.gilvum_PYR-GCK          AAVLADGVTTIHNAAREPDVVDLCTMLNQMGAQVTGAGSSTLTIIGVDRL
Mvan_4324|M.vanbaalenii_PYR-1       AAVLAEGVTTIHNAAREPDVVDLCTMLNQMGAQVTGAGSSTLTITGVDRL
Mb1348|M.bovis_AF2122/97            AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRL
Rv1315|M.tuberculosis_H37Rv         AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRL
MLBr_01150|M.leprae_Br4923          AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGVGSPTMTITGVPRL
MAV_1531|M.avium_104                AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQVEGAGSPTMTITGVPRL
MMAR_4083|M.marinum_M               AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQIEGAGSPTMTITGVPRL
MUL_3950|M.ulcerans_Agy99           AAVVAEGVTTIHNAAREPDVVDLCTMLNQMGAQIEGAGSPTMTITGVPRL
MSMEG_4932|M.smegmatis_MC2_155      AAVVAEGVTTIHNAAREPDVVDLCAMLNEMGAQISGAGTSTLTITGVDRL
TH_1554|M.thermoresistible__bu      AAVLAEGTTTIHNAAREPDVVDLCTMLNEMGAQISGAGTPTMTITGVDRL
MAB_1457|M.abscessus_ATCC_1997      AAVLADGVTTIHNAAREPDVVDLCTMLVQMGAEIEGAGTSTLTVTGVSAL
                                    ***:*:*.****************:** :***:: *.*:.*:*: **  *

Mflv_2322|M.gilvum_PYR-GCK          HPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPAHLQLVLHKLHDAGA
Mvan_4324|M.vanbaalenii_PYR-1       YPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPAHLQLVLHKLHDAGA
Mb1348|M.bovis_AF2122/97            HPTEHRVIGDRIVAATWGIAAAMTRGDISVAGVDPAHLQLVLHKLHDAGA
Rv1315|M.tuberculosis_H37Rv         HPTEHRVIGDRIVAATWGIAAAMTRGDISVAGVDPAHLQLVLHKLHDAGA
MLBr_01150|M.leprae_Br4923          YPTEHRVIGDRIVAATWGIAAAMTRGDIAVTGVDPAHLQLVLHKLHDAGA
MAV_1531|M.avium_104                YPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPAHLQVVLHKLHDAGA
MMAR_4083|M.marinum_M               HPTEHRVIGDRIVAATWGIAAAMTRGDITVTGIDPSHLQLVLHKLYDAGA
MUL_3950|M.ulcerans_Agy99           HPTEHRVIGDRIVAATWGIAAAMTRGDITVTGIDPSHLQLVLHKLYDAGA
MSMEG_4932|M.smegmatis_MC2_155      YPTEHRVIGDRIVAATWGIAAAMTRGDITVTGVDPQHLQLVLHKLHDAGA
TH_1554|M.thermoresistible__bu      YPTEHRVIGDRIVAATWGIAAAMTRGDISVTGVDPQHLQLVLHKLHDAGA
MAB_1457|M.abscessus_ATCC_1997      HPTEHRVIGDRIVAATWGLAAAMTRGDVTVTGVDPEHLQLVLHKLHDAGA
                                    :*****************:********::*:*:** ***:*****:****

Mflv_2322|M.gilvum_PYR-GCK          TVTQSDDGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIGLAAVADGTSM
Mvan_4324|M.vanbaalenii_PYR-1       TVTQTDDGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIGLAAVADGTSM
Mb1348|M.bovis_AF2122/97            TVTQTDASFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
Rv1315|M.tuberculosis_H37Rv         TVTQTDASFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
MLBr_01150|M.leprae_Br4923          TVTQTDDSFRVAQYERPKAVNVATLPFPGFPTDLQPMAIALTSIADGTSM
MAV_1531|M.avium_104                TVTQTDDSFRVTQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
MMAR_4083|M.marinum_M               TVTQTDDSFRIVQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
MUL_3950|M.ulcerans_Agy99           TVTQTDDSFRIVQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
MSMEG_4932|M.smegmatis_MC2_155      TVTQNDNGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIGLAAIADGTSM
TH_1554|M.thermoresistible__bu      TVTQHDNGFRVVQYERPKAVNVATLPFPGFPTDLQPMAIALASIADGTSM
MAB_1457|M.abscessus_ATCC_1997      TVTQSDDGFRVVQYERPKAINVATLPFPGFPTDLQPMAIGLAAIADGTSM
                                    **** * .**:.*******:*******************.*:::******

Mflv_2322|M.gilvum_PYR-GCK          ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQLSSAPVWSSDIRA
Mvan_4324|M.vanbaalenii_PYR-1       ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQLSSAPVWSSDIRA
Mb1348|M.bovis_AF2122/97            ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
Rv1315|M.tuberculosis_H37Rv         ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
MLBr_01150|M.leprae_Br4923          ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
MAV_1531|M.avium_104                ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
MMAR_4083|M.marinum_M               ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGLPQLSSAPVWCSDIRA
MUL_3950|M.ulcerans_Agy99           ITENVFEARFRFVEEMIRLGADALTDGHHAVVRGLPQLSSAPVWCSDIRA
MSMEG_4932|M.smegmatis_MC2_155      ITENVFEARFRFVEEMIRLGADARTDGHHAVVRGIPQLSSAPVWSSDIRA
TH_1554|M.thermoresistible__bu      ITENVFEARFRFVEEMVRLGADARTDGHHAVVRGLPQLSSAPVWSSDIRA
MAB_1457|M.abscessus_ATCC_1997      ITENVFEARFRFVEEMMRLGADARTDGHHAVVRGIRQLSSAPVWSSDIRA
                                    ****************:****** **********: ********.*****

Mflv_2322|M.gilvum_PYR-GCK          GAGLVLAGLVADGDTEVHDVFHIDRGYPKFVENLAALGAEIERVT-
Mvan_4324|M.vanbaalenii_PYR-1       GAGLVLAGLVADGDTEVHDVFHIDRGYPKFVENLVSLGAEIERVN-
Mb1348|M.bovis_AF2122/97            GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLVSLGAEIERVCC
Rv1315|M.tuberculosis_H37Rv         GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLVSLGAEIERVCC
MLBr_01150|M.leprae_Br4923          GAGLVLAGLVADGDTEVYDVFHIDRGYPLFVENLANLGAEIERVCL
MAV_1531|M.avium_104                GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVENLAILGAEIERVE-
MMAR_4083|M.marinum_M               GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVEYLGILGAEIERVQ-
MUL_3950|M.ulcerans_Agy99           GAGLVLAGLVADGDTEVHDVFHIDRGYPLFVEYLGILGAEIERVQ-
MSMEG_4932|M.smegmatis_MC2_155      GAGLVLAGLVADGETEVHDVFHIDRGYPLFVENLVSLGAEIERVSS
TH_1554|M.thermoresistible__bu      GAGLVLAGLVADGDTEVHDVFHIDRGYPRFVENLKSLGAEIERIS-
MAB_1457|M.abscessus_ATCC_1997      GAGLVLAGLVADGVTEVYDVFHIDRGYPLFVENLQSLGAEVERVS-
                                    ************* ***:********** *** *  ****:**: