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KFVINSGTLAETIAAAISSLPTRPAASILGGVLVEAQLGTVTFSSFNYNRATTRLTAADVADTDTVVVAG RLLAAVGANLPKGPECQVTVGNAEMVIATPRTEFRLPVLHATDYPRLPVMGSEDAIGCVNAESFSEAVHV IGRFASTDALPAEFTALNIDCRPGQMRLCATDRYMIARREIEWTGAGEANINVPAADLLATIKAASGNGA EPIEILWNGATLGLRTPSTTVITRVLDEEFPNVDRVLSLKSPFHAAVTVPTAELASTLKRAASIADDQNA QIDVAINSDTLSVTTTQSTAGNIDETVAAVQHGGDRKIALSSRRLHNTLSAIDDPNVTLAFLKEGHMVYA FPGAIDTNLVPPQRDTVAALMGIKGREGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3926 | dnaN_1 | - | 100% (380) | DNA polymerase III (beta chain) DnaN_1 |
| M. marinum M | MMAR_0002 | dnaN | 2e-31 | 27.57% (370) | DNA polymerase III (beta chain) DnaN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0002 | dnaN | 9e-31 | 28.57% (350) | DNA polymerase III subunit beta |
| M. gilvum PYR-GCK | Mflv_0826 | - | 8e-35 | 29.83% (352) | DNA polymerase III subunit beta |
| M. tuberculosis H37Rv | Rv0002 | dnaN | 7e-31 | 28.57% (350) | DNA polymerase III subunit beta |
| M. leprae Br4923 | MLBr_00002 | dnaN | 4e-32 | 27.64% (351) | DNA polymerase III subunit beta |
| M. abscessus ATCC 19977 | MAB_0002 | dnaN | 1e-33 | 29.43% (350) | DNA polymerase III subunit beta |
| M. avium 104 | MAV_0002 | dnaN | 5e-31 | 28.77% (365) | DNA polymerase III subunit beta |
| M. smegmatis MC2 155 | MSMEG_0001 | dnaN | 9e-36 | 31.53% (352) | DNA polymerase III subunit beta |
| M. thermoresistible (build 8) | TH_0848 | dnaN | 3e-33 | 30.50% (341) | DNA POLYMERASE III (BETA CHAIN) DNAN (DNA |
| M. ulcerans Agy99 | MUL_0002 | dnaN | 3e-32 | 27.84% (370) | DNA polymerase III subunit beta |
| M. vanbaalenii PYR-1 | Mvan_0002 | - | 8e-34 | 29.89% (368) | DNA polymerase III subunit beta |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0002|M.bovis_AF2122/97 MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGS
Rv0002|M.tuberculosis_H37Rv MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGS
MUL_0002|M.ulcerans_Agy99 MDAATTRAGLTDLKFRLVPESFADAVSWVAKNLPTRPAVPVLSGVLLTGS
MLBr_00002|M.leprae_Br4923 MDLAKTNVGCSDLKFCLARESFASAVSWVAKYLPTRPTVPVLSGVLLTGS
MAV_0002|M.avium_104 -----------------MRESFADAVSWVAKSLPSRPAVPVLSGVLLSGT
Mflv_0826|M.gilvum_PYR-GCK -MNVATTAGLSDLKFRLTREDFADAVAWVARNLPSRPTVPVLAGVLLTGS
Mvan_0002|M.vanbaalenii_PYR-1 -MNVPTTAGLTDLKFRLTREDFADAVAWVARNLPSRPTVPVLAGVLLTGS
MSMEG_0001|M.smegmatis_MC2_155 --MATTTAGLTDLKFRVVREDFADAVAWVARSLPTRPTIPVLAGVLLTGT
TH_0848|M.thermoresistible__bu --VATTTVGLTDLKVRLVRDDFADAVAWVARSLPSRPTVPVLAGVLLTGS
MAB_0002|M.abscessus_ATCC_1997 MDLASPTAADTSLKFRVARDDFADSVAWVARSLPSRPTVPVLAGVLLTAH
MMAR_3926|M.marinum_M ------------MKFVINSGTLAETIAAAISSLPTRPAASILGGVLVEAQ
:*.::: . **:**: .:*.***: .
Mb0002|M.bovis_AF2122/97 DNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKP-VG
Rv0002|M.tuberculosis_H37Rv DNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKP-VD
MUL_0002|M.ulcerans_Agy99 DEGLTISGFDYEVSAEVRVPAEIASPGTVLVSGRLLSDITRALPKKP-VD
MLBr_00002|M.leprae_Br4923 DSGLTISGFDYEVSAEVQVAAEIASSGSVLVSGRLLSDITRALPNKP-VH
MAV_0002|M.avium_104 DEGLTISGFDYEVSAEAQVAAEIASPGSVLVSGRLLSDIVRALPNKP-ID
Mflv_0826|M.gilvum_PYR-GCK DEGLTVSGFDYEVSAEVQIPAEIASPGSVLVSGRLLSDIVRSLPAKP-VD
Mvan_0002|M.vanbaalenii_PYR-1 DEGLTISGFDYEVSAEVQIPAEIASPGSVLVSGRLLSDIVRALPAKP-VD
MSMEG_0001|M.smegmatis_MC2_155 DEGLTISGFDYEVSAEVKVSAEIASAGSVLVSGRLLSDITKALPAKP-VE
TH_0848|M.thermoresistible__bu DDGLTISSFDYEVSAEVQIPAEIAAPGTVLVSGRLLSEITRALPNKP-VD
MAB_0002|M.abscessus_ATCC_1997 DTGLTLSGFDYEVSAQVKVPAEVAAAGNALVSGRLLSDITRSLPNKP-VD
MMAR_3926|M.marinum_M LGTVTFSSFNYNRATTRLTAADVADTDTVVVAGRLLAAVGANLPKGPECQ
:*.*.*:*: :: *::. ....:*:****: : ** *
Mb0002|M.bovis_AF2122/97 VHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLP--EETGLLPAELFAEA
Rv0002|M.tuberculosis_H37Rv VHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLP--EETGLLPAELFAEA
MUL_0002|M.ulcerans_Agy99 FYVDGNRVALTCGNARFSLPTMAVEDYPTLPTLP--EDTGTLPAELFSEA
MLBr_00002|M.leprae_Br4923 FYVDGNRVALTCGSARFSLPTMAVEDYPTLPTLP--DETGTLPSDVFAEA
MAV_0002|M.avium_104 FYVDGNRVALNCGSARFSLPTMAVEDYPTLPTLP--EETGTLPADLFAEA
Mflv_0826|M.gilvum_PYR-GCK VSVEGTRVSLTCGSARFSLPTMAVEDYPTLPTLP--DETGVVSADLFAEA
Mvan_0002|M.vanbaalenii_PYR-1 VSVEGTRVSLTCGSARFSLPTMPVEDYPTLPTLP--DETGVVSSDLFAEA
MSMEG_0001|M.smegmatis_MC2_155 VSVEGTRVSLTCGSARFSLPTLAVEDYPALPALP--EETGVIASDLFAEA
TH_0848|M.thermoresistible__bu LSVEGTRVSLTCGSARFSLPTMAVEDYPALPELP--AETGSVPADLFAEA
MAB_0002|M.abscessus_ATCC_1997 VALEGTRLLISCGSAKFSLPSMPVEDYPALPSLP--EETGALGADVFSEA
MMAR_3926|M.marinum_M VTVGNAEMVIATPRTEFRLPVLHATDYPRLPVMGSEDAIGCVNAESFSEA
. : . .: : :.* ** : . *** ** : * : :: *:**
Mb0002|M.bovis_AF2122/97 ISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASS
Rv0002|M.tuberculosis_H37Rv ISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASS
MUL_0002|M.ulcerans_Agy99 IGQVAITAGRDDTLPMLTGIRVEISGEKVVLAATDRFRLAVRELTWNALS
MLBr_00002|M.leprae_Br4923 IGQVAIAAGRDYTLPMLTGIRIEISGDTVVLAATDRFRLAVRELKWSVLS
MAV_0002|M.avium_104 IGQVAIAAGRDDTLPMLTGIRVEISGDTVVLAATDRFRLAVRELTWSAAS
Mflv_0826|M.gilvum_PYR-GCK IGQVAVAAGRDDTLPMLTGIRVEISGEKVVLAATDRFRLAVRELTWSAGA
Mvan_0002|M.vanbaalenii_PYR-1 IGQVAVAAGRDDTLPMLTGIRVEISGEKVVLAATDRFRLAVRELTWSTGA
MSMEG_0001|M.smegmatis_MC2_155 IGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVRELTWVTTA
TH_0848|M.thermoresistible__bu IGQVAVAAGRDDTLPMLTGIRVEISGDRMVLAATDRFRLAVRELTWTTKT
MAB_0002|M.abscessus_ATCC_1997 IGQVAVAAGKDDTLPMLTGIRVEINGDTVVLAATDRFRLAVRELNWTSGS
MMAR_3926|M.marinum_M VHVIGRFASTDALPAEFTALNIDCRPGQMRLCATDRYMIARREIEWTGAG
: :. *. * . :*.:.:: : *.****: :* **: *
Mb0002|M.bovis_AF2122/97 PDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGK
Rv0002|M.tuberculosis_H37Rv PDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGK
MUL_0002|M.ulcerans_Agy99 PDIEAAVLVPAKTLGEAAKANTDGSEVRLSLGAGMGVGKDGLLGISGDGK
MLBr_00002|M.leprae_Br4923 SDFEASVLVPAKTLVEVAKAGTDGSGVCLSLGAGVGVGKDGLFGISGGGK
MAV_0002|M.avium_104 PDIEAAVLVPAKTLAEAARTGIDGSDVRLSLGAGAGVGKDGLLGISGNGK
Mflv_0826|M.gilvum_PYR-GCK AGVEAAVLVPAKTLAEAAKAGTDGTEVHLALGQGPTVGKEGLLGIRSKGK
Mvan_0002|M.vanbaalenii_PYR-1 AGVEAAVLVPAKTLAEAAKAGTDGNEVHLALGAGPSVGKEGLLGIRSKGK
MSMEG_0001|M.smegmatis_MC2_155 GDVEAAVLVPAKTLAEAAKAGTDGNQVHLALGSGASVGKDGLLGIRSEGK
TH_0848|M.thermoresistible__bu PDVEAAVLVPAKTLAEAAKTGLDGSEVQLALGAGPSVGQDGLLGIRSEGK
MAB_0002|M.abscessus_ATCC_1997 GETSAAVLVPAKTLSEAAKSASSGSDVQLALGAGSAIGSEGLLGIVSDGK
MMAR_3926|M.marinum_M ---EANINVPAADLLATIKAASGNGAEPIEILWN-----GATLGLRTPST
.* : *** * . :: .. : : . . :*: ..
Mb0002|M.bovis_AF2122/97 RSTTRLLDAEFPKFRQLLPTEH--TAVATMDVAELIEAIKLVALVADR-G
Rv0002|M.tuberculosis_H37Rv RSTTRLLDAEFPKFRQLLPTEH--TAVATMDVAELIEAIKLVALVADR-G
MUL_0002|M.ulcerans_Agy99 RSTTRLLDAEFPKFRQLLPAEH--TAVASADVAELTEAIKLVALVADR-G
MLBr_00002|M.leprae_Br4923 RSTTRLLDAEFPKFRQLLPAEH--TAVATIDVAELTEAIKLVALVADR-G
MAV_0002|M.avium_104 RSTTRLLDAEFPKFRQLLPAEH--TAVATINVAELTEAIKLVALVADR-G
Mflv_0826|M.gilvum_PYR-GCK RSTTRLLDAEFPKFRQLLPTEH--TAIATIGVAELTEAIKRVALVADR-G
Mvan_0002|M.vanbaalenii_PYR-1 RSTTRLLDAEFPKFRQLLPTEH--TAIATIGVAELTEAIKRVALVADR-G
MSMEG_0001|M.smegmatis_MC2_155 RSTTRLLDAEFPKFRQLLPAEH--TAVATIGVAELTEAIKRVALVADR-G
TH_0848|M.thermoresistible__bu RSTTRLLDAEFPKFRQLLPTEH--TAMATIGVGELTEAIKRVALVADR-G
MAB_0002|M.abscessus_ATCC_1997 RSTTRLLDAEFPKFRQLLPTEH--TALATIAISELVEAIKRVALVADR-G
MMAR_3926|M.marinum_M TVITRVLDEEFPNVDRVLSLKSPFHAAVTVPTAELASTLKRAASIADDQN
**:** ***:. ::*. : * .: .** .::* .* :** .
Mb0002|M.bovis_AF2122/97 AQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGL
Rv0002|M.tuberculosis_H37Rv AQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGL
MUL_0002|M.ulcerans_Agy99 AQVRMEFADGMLRLSAGADDVGRAEEDIAVEFAGQPLTIAFNPTYLIDGL
MLBr_00002|M.leprae_Br4923 AQVRMEFGDGILRLSAGADDVGRAEEDLAVAFTGEPLTIAFNPNYLTDGL
MAV_0002|M.avium_104 AQVRMEFSEGSLRLSAGADDVGRAEEDLAVDFAGEPLTIAFNPTYLTDGL
Mflv_0826|M.gilvum_PYR-GCK AQVRMEFADDVLRLSAGADDVGRAEEDLPVQFSGDPLTIAFNPSYLTDGL
Mvan_0002|M.vanbaalenii_PYR-1 AQVRMEFADGVLRLSAGADDVGRAEEDLPVEFSGDPLTIAFNPTYLTDGL
MSMEG_0001|M.smegmatis_MC2_155 AQIRMEFSDDTLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGL
TH_0848|M.thermoresistible__bu AQVRMEFADDVLHLSAGADDVGRAEEDLPVSFSGEPLTIAFNPGYLTDGL
MAB_0002|M.abscessus_ATCC_1997 AQIRLEFEPGLLRLSAGADDVGRAEEELEVEFVGEPLTIAFNPTYLTDGL
MMAR_3926|M.marinum_M AQIDVAINSDTLSVTTTQSTAGNIDETVAAVQHGGDRKIALSSRRLHNTL
**: : : . : ::: . .*. :* : . * .**:.. * : *
Mb0002|M.bovis_AF2122/97 SSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYL
Rv0002|M.tuberculosis_H37Rv SSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYL
MUL_0002|M.ulcerans_Agy99 ASLHSERVSFGFTTPGKPALLRPASAEDRIVSGPGDQGPFAAVPTDYVYL
MLBr_00002|M.leprae_Br4923 ASVHSERVSFGFTTPSKPALLRPTSNDD---VHPTHDGPFPALPTDYVYL
MAV_0002|M.avium_104 GSVRSERVSFGFTTPGKPALLRPASDDD---SPPSGSGPFSALPTDYVYL
Mflv_0826|M.gilvum_PYR-GCK GSLHAERVTFGFTTPSRPAVLRPAGDDD---GSAAGSGPYPAAQTDYVYL
Mvan_0002|M.vanbaalenii_PYR-1 SSLHAERVTFGFTTPSRPAVLRPAAEDD---GGAGGSGPFPAAQTDYVYL
MSMEG_0001|M.smegmatis_MC2_155 GSLHSERVTFGFTTPSRPAVLRPAGEDD---GANGGSGPFPAAKTDYVYL
TH_0848|M.thermoresistible__bu GALHSERVTFGFTTPSKPAVLRPATEAD---AALNGNGPFPAAETDYVYL
MAB_0002|M.abscessus_ATCC_1997 GSLHSNRVTFGFTTPSRPAVLRPADDDQ---SSPEGSGPFTAAQTDYVYL
MMAR_3926|M.marinum_M SAIDDPNVTLAFLKEGHMVYAFPGAIDT----------NLVPPQRDTVAA
.:: .*::.* . .: . * . * *
Mb0002|M.bovis_AF2122/97 LMPVRLPG--
Rv0002|M.tuberculosis_H37Rv LMPVRLPG--
MUL_0002|M.ulcerans_Agy99 LMPVRLPG--
MLBr_00002|M.leprae_Br4923 LMPVRLPG--
MAV_0002|M.avium_104 LMPVRLPG--
Mflv_0826|M.gilvum_PYR-GCK LMPVRLPG--
Mvan_0002|M.vanbaalenii_PYR-1 LMPVRLPG--
MSMEG_0001|M.smegmatis_MC2_155 LMPVRLPG--
TH_0848|M.thermoresistible__bu LMPVRLPG--
MAB_0002|M.abscessus_ATCC_1997 LMPVRLPG--
MMAR_3926|M.marinum_M LMGIKGREGQ
** ::