For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TDAAAGVAAPPSAMAPVPYRVRSRVVESPDSATLCLEPVSEALRRPEPGEFMMLYAFGVGEAAISISGDP SVTDGSITHTIRAVGAVSRALHDAAPGSIVGVRGPFGTTWGLDEAAGRDLVMVAGGVGLCPLRPAVLGAL AQRSRYRRLTLIVGARSRADFVFAAQLEKWAQDPDIELHVTVDVPVQGWRGEVGLVTEPLRRLALDPEHT TAFLCGPEPMLRFGAEALLAKGVAAQDIRVSLERNMQCGVGWCGHCQLGPLLLCRDGPVVSYDVAGPLLR VKEL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3499 | - | - | 100% (285) | flavodoxin oxidoreductase |
| M. marinum M | MMAR_2865 | - | 3e-07 | 27.66% (188) | oxygenase |
| M. marinum M | MMAR_5066 | hmp | 3e-06 | 27.01% (211) | flavodoxin reductase Hmp |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3602 | hmp | 7e-06 | 24.79% (242) | hemoglobine-like protein |
| M. gilvum PYR-GCK | Mflv_1462 | - | 1e-08 | 29.36% (235) | ferredoxin |
| M. tuberculosis H37Rv | Rv3571 | hmp | 7e-06 | 24.79% (242) | hemoglobine-like protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0583c | - | 2e-06 | 26.58% (237) | putative oxidoreductase |
| M. avium 104 | MAV_0590 | - | 3e-07 | 27.62% (210) | oxidoreductase, electron transfer component |
| M. smegmatis MC2 155 | MSMEG_3930 | - | 1e-108 | 67.53% (271) | [NiFe] hydrogenase, gamma subunit, putative [Mycobacterium |
| M. thermoresistible (build 8) | TH_1151 | dinP | 6e-51 | 77.31% (119) | DNA polymerase IV |
| M. ulcerans Agy99 | MUL_2889 | - | 2e-08 | 28.19% (188) | oxygenase |
| M. vanbaalenii PYR-1 | Mvan_1767 | - | 6e-11 | 27.27% (275) | ferredoxin |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3602|M.bovis_AF2122/97 --------------------------------------------------
Rv3571|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
Mflv_1462|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0583c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3499|M.marinum_M --------------------------------------------------
MSMEG_3930|M.smegmatis_MC2_155 --------------------------------------------------
TH_1151|M.thermoresistible__bu --------------------------------------------------
Mvan_1767|M.vanbaalenii_PYR-1 -------------------------MAKNTIKNTAKVADTVRPTIAGAKE
MUL_2889|M.ulcerans_Agy99 MTVRHVTVGYSDGTHKTMPVRPDQSILEAAEEHGVAIVNECQSGICGTCV
Mb3602|M.bovis_AF2122/97 -----MTEAIG----DEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSD
Rv3571|M.tuberculosis_H37Rv -----MTEAIG----DEPLGDHVLELQIAEVVDETDEARSLVFAVPDGSD
MAV_0590|M.avium_104 -----MTEADSAQALDEPLGDHVLELQIAEVIAETDDARSLVFAVPDDDG
Mflv_1462|M.gilvum_PYR-GCK -----MTDVAA----DEPLGAHVLELEIADVIDETSDARSLVFRSP---A
MAB_0583c|M.abscessus_ATCC_199 -----MT--------DVPLGKHVLEVRIAEVIEETADSRSLVFEIPDG--
MMAR_3499|M.marinum_M ----MTDAAAGVAAPPSAMAPVPYRVRSRVVESPDSATLCLEPVSE----
MSMEG_3930|M.smegmatis_MC2_155 ------------------MEPVPYRVRERVVENRDSATLFLDPVNG----
TH_1151|M.thermoresistible__bu ------VFVSGPAGHGATILHADLDAFYASVEQRDDPALRGRPVIVGGGV
Mvan_1767|M.vanbaalenii_PYR-1 NPGWHLLRTIAGRITTPLLPDDYLKLANPLWSARELRGRVLEVRRETEDS
MUL_2889|M.ulcerans_Agy99 ATCTAGRYDMGRTEGLSDVERAARKILTCQTLAESDCEIELQYPVDDNAA
:
Mb3602|M.bovis_AF2122/97 DPEIPPRRL----RYAPGQFLTLRVPSERTGSVARCY-------------
Rv3571|M.tuberculosis_H37Rv DPEIPPRRL----RYAPGQFLTLRVPSERTGSVARCY-------------
MAV_0590|M.avium_104 DPDIPPERL----RYAPGQFLTLRVPSERTGSVARCY-------------
Mflv_1462|M.gilvum_PYR-GCK DAPVAPEKL----RYSPGQFLTLRVPSEKTGSVARCY-------------
MAB_0583c|M.abscessus_ATCC_199 ----AADKF----AYAPGQYLTLRIPSDRTGSVARCY-------------
MMAR_3499|M.marinum_M ALRRPEPGE----FMMLYAFGVGEAAISISGDPSVTD-------------
MSMEG_3930|M.smegmatis_MC2_155 ALRTPRPGE----FMMMYAFGIGEIAVSVSGISPEPE-------------
TH_1151|M.thermoresistible__bu VLAASYEAK----AYGVRTAMSGGQARALCPHAIVVP-------------
Mvan_1767|M.vanbaalenii_PYR-1 ATLVIKPGWGFSFDYEPGQYIGIGLLVEG-RWRWRSY-------------
MUL_2889|M.ulcerans_Agy99 LLVSGDGVVTGVDMVSPGTAVLRVDVSAMAGTIGYRAGQFAQLQVPGSDQ
Mb3602|M.bovis_AF2122/97 -SLCSSPYTDDA---LAVTVKRTADGYASNWLCDHAQVGMRIHVLAPSGN
Rv3571|M.tuberculosis_H37Rv -SLCSSPYTDDA---LAVTVKRTADGYASNWLCDHAQVGMRIHVLAPSGN
MAV_0590|M.avium_104 -SLCSSPFTDDA---LTVTVKRTADGYASNWLCDNARPGMRIHVLAPSGN
Mflv_1462|M.gilvum_PYR-GCK -SLCSSPFTGDP---LTVTIKRTADGYASNWLCDNAHAGMKMHVLAPSGT
MAB_0583c|M.abscessus_ATCC_199 -SLSSSPHLDDR---LAVTVKRTADGYGSNWICDNAHAGMHMHVLAPSGV
MMAR_3499|M.marinum_M -GSITHTIRAVG---AVSRALHDAAPG-SIVGVRGPFGTTWGLDEAAG--
MSMEG_3930|M.smegmatis_MC2_155 -TTVAHTVRAVG---AVSTALRDAAVG-SLVGLRGPFGTGWGHEVATG--
TH_1151|M.thermoresistible__bu -PRMAAYSQASA---AVFDVFRDTTPLVEPLSVDEAFLDVGGLGRLAGTP
Mvan_1767|M.vanbaalenii_PYR-1 -SLTSSPVTSKGSRTITITVKAMPEGFLSTHLVGGVAPGTIVRLAAPQGN
MUL_2889|M.ulcerans_Agy99 WRNYSYAHPADGGGDLEFIIRLLPDGAMSNYLRDHAKQGDRIALRGSKGN
: . . .
Mb3602|M.bovis_AF2122/97 FVPTTLD-ADFLLLAAGSGITP----IMSICKSALAEGGGQVTLLYANRD
Rv3571|M.tuberculosis_H37Rv FVPTTLD-ADFLLLAAGSGITP----IMSICKSALAEGGGQVTLLYANRD
MAV_0590|M.avium_104 FVPKTLG-DDFLLMAAGSGITP----IMSIAKSALSEGSGRVTLLYANRD
Mflv_1462|M.gilvum_PYR-GCK FVPKNLD-TDFLLLAAGSGITP----MLAILKSALSEGSGHVTLVYANRD
MAB_0583c|M.abscessus_ATCC_199 FVPKQLD-NDFLLLAGGSGVTP----MMAICKSALSQGSGKVVLIYANRD
MMAR_3499|M.marinum_M --------RDLVMVAGGVGLCP--LRPAVLGALAQRSRYRRLTLIVGARS
MSMEG_3930|M.smegmatis_MC2_155 --------RELVIVAGGVGLAP--LRPVIVDVLACRHMYGQVTVIAGARS
TH_1151|M.thermoresistible__bu VQIAARL-RERVRAEVGLPITVGIARTKFLAKVASQEAKPDGLLLVPPDR
Mvan_1767|M.vanbaalenii_PYR-1 FVMPDPAPASVLFLTAGSGITP---VMSMLRTLVRRGQLGDVAHVHSSPT
MUL_2889|M.ulcerans_Agy99 FYLRPIV-RPVVLVAGGTGLSA----ILAMAQSLPADPGQPVSLLYGVTS
: * : : :
Mb3602|M.bovis_AF2122/97 DRSVIFGDALRELAAKYPDR--LTVLHWLESLQGLP-----SASALAKLV
Rv3571|M.tuberculosis_H37Rv DRSVIFGDALRELAAKYPDR--LTVLHWLESLQGLP-----SASALAKLV
MAV_0590|M.avium_104 ERSVIFADALRELSAKYPDR--LTVLHWLESLQGLP-----SVTALAQLA
Mflv_1462|M.gilvum_PYR-GCK EKSVIFAETLRDLANKYPDR--LTTIHWLESVQGLP-----SVSALTALF
MAB_0583c|M.abscessus_ATCC_199 EQSVIFGAALRELAAKYPDR--LTVIHWLESVQGLP-----SQQQLATLT
MMAR_3499|M.marinum_M RADFVFAA---QLEKWAQDPDIELHVTVDVPVQGWRGEVGLVTEPLRRLA
MSMEG_3930|M.smegmatis_MC2_155 RDDFLFTP---ELRQWSSRGSIDVHLTVDIPVQGWPGEVGFVTEPLRRLP
TH_1151|M.thermoresistible__bu EPAFLHPLPVQRLXXXAADPALEVALTVDVPVQGWPGEVGLVTEPLRRLE
Mvan_1767|M.vanbaalenii_PYR-1 EDDVMFAAELSELADRHEGYRLRVRATRTEGRLDLD--------RLDEVV
MUL_2889|M.ulcerans_Agy99 AEDLCKLDELEQLEHRVAGL--QVHVTVARRDEDWSGRTGLVTDLLDEAM
. * . *
Mb3602|M.bovis_AF2122/97 APYTDRPVFICGPGPFMQAARDALAALKVPAQQVHIEVFKSLESDPFAAV
Rv3571|M.tuberculosis_H37Rv APYTDRPVFICGPGPFMQAARDALAALKVPAQQVHIEVFKSLESDPFAAV
MAV_0590|M.avium_104 APYTDRPVYICGPGAFMDSAREALETLKVPAAQIHIEVFKSLDSDPFAAV
Mflv_1462|M.gilvum_PYR-GCK APFTSREAFICGPGPFMAAAEEALTASGAAADKIHIEVFKSLDSDPFAAV
MAB_0583c|M.abscessus_ATCC_199 APFAEHEAFICGPGPFMDASEAALKGNGMPHDRVHIEVFRSLESDPFAEV
MMAR_3499|M.marinum_M LDPEHTTAFLCGPEPMLRFGAEALLAKGVAAQDIRVSLERNMQCG-----
MSMEG_3930|M.smegmatis_MC2_155 VRPERTTAYLCGPEPMMRASAEVLMGKGLRASDIRVSLERNMQCG-----
TH_1151|M.thermoresistible__bu LDPTRTAAFLCGPEPMMRHSAAALLAKGVPAENIRVSLERNMQCG-----
Mvan_1767|M.vanbaalenii_PYR-1 PDWRERQTWACGPEAMLEAAERTWKAAGI-ADRLHLERFAVARAAHGSGG
MUL_2889|M.ulcerans_Agy99 LAGGDANVYLCGPAAMVEATRTWLSANGFHRAGLYHEKFVASGAARRRTP
.: *** .:: : . .
Mb3602|M.bovis_AF2122/97 KVDDS---GDEAPATAVVELDGQTHTVSWPRTAKLLDVLLAAGLDAPFSC
Rv3571|M.tuberculosis_H37Rv KVDDS---GDEAPATAVVELDGQTHTVSWPRTAKLLDVLLAAGLDAPFSC
MAV_0590|M.avium_104 KIEDTA-EGDEPPATAVVELDGETHTVSWPRNAKLLDVLLAKGLDAPFSC
Mflv_1462|M.gilvum_PYR-GCK TIDDADDEGDSGPATVVVTLDGETHEVSWPRKAKLLDVLLNKGLDAPFSC
MAB_0583c|M.abscessus_ATCC_199 VLAEPS-DDDEPPATATVELDGETHEVSWPRSTVLLDVLLAKGLDAPFSC
MMAR_3499|M.marinum_M --------------------------VGWCGHCQLGPLLLCR--DGPVVS
MSMEG_3930|M.smegmatis_MC2_155 --------------------------IGWCGHCQLGPLLLCR--DGPVVG
TH_1151|M.thermoresistible__bu --------------------------IGWCGHCQLGPLLLCR--DGPVVG
Mvan_1767|M.vanbaalenii_PYR-1 TVEFSR----------------SGKAATVDGATSLMDAGEAAGIQMPFGC
MUL_2889|M.ulcerans_Agy99 ARLDYS---ALDLAAVRRSGRGIAVVIGGSIAGIAAAKVCSDTFDRVIVL
: .
Mb3602|M.bovis_AF2122/97 REGHCGACACTLRAGKVNMGVNDVLEQQDLDEGLILACQSRPESDSVEVT
Rv3571|M.tuberculosis_H37Rv REGHCGACACTLRAGKVNMGVNDVLEQQDLDEGLILACQSRPESDSVEVT
MAV_0590|M.avium_104 REGHCGACACTLRKGQVSMEVNDVLEQQDLDEGLILACQSHPESDSVEVT
Mflv_1462|M.gilvum_PYR-GCK REGHCGACAVLKKSGDIEMEVNDVLEQQDLDEGLILACQAHPTSDSVEVT
MAB_0583c|M.abscessus_ATCC_199 REGHCMTCACVLKDGKVRMLVNDALSQNDIDDGYILACQAVPETDDVNVT
MMAR_3499|M.marinum_M YD-----------------VAGPLLRVKEL--------------------
MSMEG_3930|M.smegmatis_MC2_155 YD-----------------VADPLLAVKEL--------------------
TH_1151|M.thermoresistible__bu YD-----------------VAAPLLAVEEL--------------------
Mvan_1767|M.vanbaalenii_PYR-1 RMGICQSCVVGLLDG----HVRDLRTGVEHEPGTRVQTCVSAASGDCVLD
MUL_2889|M.ulcerans_Agy99 EKDDPHRRREGRPGAAQGWHLHHLLTAGQIELERFFPGIVDDMVREGAFK
:
Mb3602|M.bovis_AF2122/97 YDE-----------------------------------------------
Rv3571|M.tuberculosis_H37Rv YDE-----------------------------------------------
MAV_0590|M.avium_104 YDD-----------------------------------------------
Mflv_1462|M.gilvum_PYR-GCK FDE-----------------------------------------------
MAB_0583c|M.abscessus_ATCC_199 FDE-----------------------------------------------
MMAR_3499|M.marinum_M --------------------------------------------------
MSMEG_3930|M.smegmatis_MC2_155 --------------------------------------------------
TH_1151|M.thermoresistible__bu --------------------------------------------------
Mvan_1767|M.vanbaalenii_PYR-1 V-------------------------------------------------
MUL_2889|M.ulcerans_Agy99 VDMAAQYRIRLGGTWKKPGTSDIEIVCAGRPLLEWCVRRRLDDEPRIDFR
Mb3602|M.bovis_AF2122/97 --------------------------------------------------
Rv3571|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
Mflv_1462|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0583c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3499|M.marinum_M --------------------------------------------------
MSMEG_3930|M.smegmatis_MC2_155 --------------------------------------------------
TH_1151|M.thermoresistible__bu --------------------------------------------------
Mvan_1767|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2889|M.ulcerans_Agy99 YESEVTDLVFDRATNAVIGVAVPGDGGEPEVIPAEFVLDASGKNTHVPEF
Mb3602|M.bovis_AF2122/97 --------------------------------------------------
Rv3571|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
Mflv_1462|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0583c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3499|M.marinum_M --------------------------------------------------
MSMEG_3930|M.smegmatis_MC2_155 --------------------------------------------------
TH_1151|M.thermoresistible__bu --------------------------------------------------
Mvan_1767|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2889|M.ulcerans_Agy99 LERIGIGAPEVEQDIINCFYSTMQHQVPPERQWQDKVMVICYAYRPYEDT
Mb3602|M.bovis_AF2122/97 --------------------------------------------------
Rv3571|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
Mflv_1462|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0583c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3499|M.marinum_M --------------------------------------------------
MSMEG_3930|M.smegmatis_MC2_155 --------------------------------------------------
TH_1151|M.thermoresistible__bu --------------------------------------------------
Mvan_1767|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2889|M.ulcerans_Agy99 YAAQYYTDSSRTILSTSLVAYNCYSPLRTVREFREFADLMPSPVIGENID
Mb3602|M.bovis_AF2122/97 --------------------------------------------------
Rv3571|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
Mflv_1462|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0583c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3499|M.marinum_M --------------------------------------------------
MSMEG_3930|M.smegmatis_MC2_155 --------------------------------------------------
TH_1151|M.thermoresistible__bu --------------------------------------------------
Mvan_1767|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2889|M.ulcerans_Agy99 GLQPASPIYNFRYPNMLRLHYEKKRNLPRALLAVGDAYTSADPVSGLGMS
Mb3602|M.bovis_AF2122/97 --------------------------------------------------
Rv3571|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
Mflv_1462|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0583c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3499|M.marinum_M --------------------------------------------------
MSMEG_3930|M.smegmatis_MC2_155 --------------------------------------------------
TH_1151|M.thermoresistible__bu --------------------------------------------------
Mvan_1767|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2889|M.ulcerans_Agy99 LALKEVREMQLLLSKYGPTHRELPRKYYRTIAKMADTAWFVIREQNLRLN
Mb3602|M.bovis_AF2122/97 --------------------------------------------------
Rv3571|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0590|M.avium_104 --------------------------------------------------
Mflv_1462|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0583c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3499|M.marinum_M --------------------------------------------------
MSMEG_3930|M.smegmatis_MC2_155 --------------------------------------------------
TH_1151|M.thermoresistible__bu --------------------------------------------------
Mvan_1767|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2889|M.ulcerans_Agy99 WLKDVDKKRPFYFGALTWYMDRLLELVHDDLDAYREFLAVVHLVKPPLAL
Mb3602|M.bovis_AF2122/97 -------------------------------------------------
Rv3571|M.tuberculosis_H37Rv -------------------------------------------------
MAV_0590|M.avium_104 -------------------------------------------------
Mflv_1462|M.gilvum_PYR-GCK -------------------------------------------------
MAB_0583c|M.abscessus_ATCC_199 -------------------------------------------------
MMAR_3499|M.marinum_M -------------------------------------------------
MSMEG_3930|M.smegmatis_MC2_155 -------------------------------------------------
TH_1151|M.thermoresistible__bu -------------------------------------------------
Mvan_1767|M.vanbaalenii_PYR-1 -------------------------------------------------
MUL_2889|M.ulcerans_Agy99 MKPGIASRVIGKWARTRLSGQKTLIARNYENHTAPAEPADQLVTVGDLR