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APDNRTLSVGTLTRVEGEGALYVSLKDGELDRVELNIYEPPRFFEAFLRGRAHTEPPDLTARICGICPVA YQVSACNALEGACGVELDADLIELRRLLYCGEWIHSHVLHICLLHAPDFLGYPDAIAFARDEREIVERGL RLKKAGNQLMEFVGGRAIHPINVRLGGFYSVPTRSDFAPMAEQLRRALDDALATVEWVAGFEFPDLEFDH EFLALTTPDRYPIENGTIARSAGPVFPVDEFTDHVVELQVPHSTALHATLDGGCHVTGPLARYALNSSLL TPIAAQAAARAGLSAQCRNPFRSIIVRAVEVVYAIEEALRIIENYQRPARPFVEVPARAGVGHGVSEAPR GLLYHRYRIDDAGLVSAATIIPPTSQNQAAIEADLARVVSENLALDDEVLTTMCERAIRNYDPCISCSTH FLTLTLERG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3497 | - | - | 100% (430) | coenzyme F420-reducing hydrogenase, alpha subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3928 | - | 0.0 | 72.43% (428) | [NiFe] hydrogenase, alpha subunit, putative [Mycobacterium |
| M. thermoresistible (build 8) | TH_1153 | - | 0.0 | 71.63% (430) | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4113 | - | 3e-31 | 28.09% (477) | nickel-dependent hydrogenase, large subunit |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3497|M.marinum_M MAPDNRTLSVGTLTRVEGEGALYVSLKD-GELDRVELNIYEPPRFFEAFL
MSMEG_3928|M.smegmatis_MC2_155 MNPEVRTLSVGALARVEGEGALHVTLRD-GAVVGTQLNIYEPPRFFEAFL
TH_1153|M.thermoresistible__bu VTPEIRTLTVGALTRVEGEGALRITLRD-GQVHRAELNIYEPPRFFEAFL
Mvan_4113|M.vanbaalenii_PYR-1 ---MSKKLVIDPVTRIEGHGKVTVHLDDDGNVVDARLHVVEF-RGFEKFV
:.* :..::*:**.* : : * * * : ..*:: * * ** *:
MMAR_3497|M.marinum_M RGRAHTEPPDLTARICGICPVAYQVSACNALEGACG------VELDADLI
MSMEG_3928|M.smegmatis_MC2_155 RGRAHTEPPDLTARVCGICPVAYQVSACNAIEDACG------VTVDPEIV
TH_1153|M.thermoresistible__bu RGRAHTEPPDLTARVCGICPVAYQVSACNALEDACG------VRLEPDLL
Mvan_4113|M.vanbaalenii_PYR-1 QGHPYWEAPMLMQRICGICFVSHHLCGAKVLDDMIGAGTAAEVRVTRTAE
:*:.: *.* * *:**** *::::...:.::. * * :
MMAR_3497|M.marinum_M ELRRLLYCGEWIHSHVLHICLLHAPDFLG-------YPDAIAFARDEREI
MSMEG_3928|M.smegmatis_MC2_155 QLRRLLYCGEWIHSHALHIFLLHLPDFLG-------HPDGISLAREHPEL
TH_1153|M.thermoresistible__bu ALRRLLYCGEWISSHALHIVMLHAPDFLG-------YPDAIVMAGDHPRF
Mvan_4113|M.vanbaalenii_PYR-1 KIRRLGHYAQMLQSHATAYFYLVVPEMMFGMDAAPEQRNLLGLIEANPEL
:*** : .: : **. * *::: : : : . .:
MMAR_3497|M.marinum_M VERGLRLKKAGNQLMEFVGGRAIHPINVRLGGFYSVPTRSDFAPMAEQLR
MSMEG_3928|M.smegmatis_MC2_155 VERGLSLKKTGNRIMEQIGGRAIHPVNVRLGGFYSAPKPGDLKSLAALLR
TH_1153|M.thermoresistible__bu VGRGMALKKAGNRLLEQIGGRAVHPINMRLGGFYSVPTRAELGPLAETLR
Mvan_4113|M.vanbaalenii_PYR-1 MRRVIMLRKWGQEVIKTVFGRRMHGINSVPGGVDKNLSRAECDRLLDGEE
: * : *:* *:.::: : ** :* :* **. . . .: : .
MMAR_3497|M.marinum_M ------RALDDALATVEWVAGFEFPDLEFDHEFLALTTPDRYPIENG---
MSMEG_3928|M.smegmatis_MC2_155 ------KSLDDALYTVREVADLDCPDVVFDHEFLALGTADAYPIESG---
TH_1153|M.thermoresistible__bu ------RALDDASYIARAVAGFDFPDVEFDHELLALGAPDRYPIEDG---
Mvan_4113|M.vanbaalenii_PYR-1 GLASFDDVMDYAQDGLRLFYDFHEKHRRQVDGFAKVPALNMCLVDADGNV
:* * . . .:. . . : : : : :: .
MMAR_3497|M.marinum_M ----------TIARSAGPVFPVDEFTDHVVELQVPHSTALHATLD-----
MSMEG_3928|M.smegmatis_MC2_155 ----------AIVRSAGPSFPLADFTTHVGEAQVPHSTALHAALD-----
TH_1153|M.thermoresistible__bu ----------VIRRTTGEPFGPSEFADHVVEAQVPHSTALHATLD-----
Mvan_4113|M.vanbaalenii_PYR-1 DYYHGALRIVDENKCIVREFDYHDYLDHFSEAVEPWSYMKFPFLKDLGRE
: * :: *. * * * .. *.
MMAR_3497|M.marinum_M GGCHVTGPLARYALNSSLLTPIAAQAAARAGLSAQCRN---PFRSIIVRA
MSMEG_3928|M.smegmatis_MC2_155 DGRYLTGPLARYSLNSAHLPPIAREAATSAGLGAQCRN---PFRSIVVRA
TH_1153|M.thermoresistible__bu GRRYITGPLARYNLNYAQLSPLARQLAAEAGLGARCWN---PFRSIVVRA
Mvan_4113|M.vanbaalenii_PYR-1 EGSVRVGPLARMNVTNSLSTPLAQEALERFHAYTGGSPNNMTLHTNWARA
.***** :. : .*:* : : .::: .**
MMAR_3497|M.marinum_M VEVVYAIEEALRIIENYQRPARPFVEVP---ARAGVGHGVSEAPRGLLYH
MSMEG_3928|M.smegmatis_MC2_155 VEVVFAIEEALRIIAEYQEPPRPFVEVP---ARAGVGHGVSEAPRGLLYH
TH_1153|M.thermoresistible__bu VEVVYAIEEALRIIDGYRRPDRPYVEVP---ARPGVGFGVSEAPRGLLYH
Mvan_4113|M.vanbaalenii_PYR-1 IEVLHAAELIGELLRDPELHGDDLVVTPGGDAWVGEGIGVVEAPRGTLLH
:**:.* * .:: . * .* * * * ** ***** * *
MMAR_3497|M.marinum_M RYRIDDAGLVSAATIIPPTSQNQAAIEADLARVVSENLALD---DEVLTT
MSMEG_3928|M.smegmatis_MC2_155 RYEIGHDGLVRTATLIPPTAQNQAAIEHELAVLVAANLDRD---DAELTQ
TH_1153|M.thermoresistible__bu RYEIGADGLIAAADIVPPTSQNQAAIEHEMKRLVESDPTLG---DAELTA
Mvan_4113|M.vanbaalenii_PYR-1 HYRAGVGGDITFANLIVATTHNNQVLNRTVRSVAEDYLVGHGEITEGMMN
:*. . * : * :: .*::*: .:: : :. :
MMAR_3497|M.marinum_M MCERAIRNYDPCISCSTHFL-------TLTLERG---------
MSMEG_3928|M.smegmatis_MC2_155 LCERAIRNHDPCISCATHFL-------TLTLDRG---------
TH_1153|M.thermoresistible__bu LCERSIRNWDPCISCSTHFL-------TLEVDRGDR-------
Mvan_4113|M.vanbaalenii_PYR-1 AIEVGIRAFDPCLSCATHALGQMPLIVTVHGPAGDVVDERVRS
* .** ***:**:** * *: *