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M. marinum M MMAR_2402 (hisI)

annotation: phosphoribosyl-AMP 1,6 cyclohydrolase HisI
coordinates: 2897161 - 2897496
length: 111

MTLDPNVAARLKRNAEGLFTAVVQERGSGDVLMVAWMDDDALDRTLKTREATYYSRSRGEQWVKGATSGH
TQHVHSVRLDCDGDTVLLTVDQVGGACHTGDHTCFDATVLL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2402hisI-100% (111)phosphoribosyl-AMP 1,6 cyclohydrolase HisI

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1632hisI6e-5689.19% (111) phosphoribosyl-AMP cyclohydrolase
M. gilvum PYR-GCKMflv_3606-7e-5687.39% (111) phosphoribosyl-AMP cyclohydrolase
M. tuberculosis H37RvRv1606hisI6e-5689.19% (111) phosphoribosyl-AMP cyclohydrolase
M. leprae Br4923MLBr_01264hisI8e-5484.68% (111) phosphoribosyl-AMP cyclohydrolase
M. abscessus ATCC 19977MAB_2663c-2e-4069.72% (109) phosphoribosyl-AMP cyclohydrolase
M. avium 104MAV_3180hisI7e-5487.39% (111) phosphoribosyl-AMP cyclohydrolase
M. smegmatis MC2 155MSMEG_3212hisI8e-5486.49% (111) phosphoribosyl-AMP cyclohydrolase
M. thermoresistible (build 8)TH_1156hisI21e-4776.58% (111) Probable phosphoribosyl-AMP 1,6 cyclohydrolase hisI
M. ulcerans Agy99MUL_1579hisI1e-6198.20% (111) phosphoribosyl-AMP cyclohydrolase
M. vanbaalenii PYR-1Mvan_2811hisI6e-5387.16% (109) phosphoribosyl-AMP cyclohydrolase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2402|M.marinum_M               MT-LDPNVAARLKRNAEGLFTAVVQERGSGDVLMVAWMDDDALDRTLKTR
MUL_1579|M.ulcerans_Agy99           MT-LDPNVAARLKRNADGLFTAVVQERGSGDVLMVAWMDDDALDRTLKTR
Mb1632|M.bovis_AF2122/97            MT-LDPKIAARLKRNADGLVTAVVQERGSGDVLMVAWMNDEALARTLQTR
Rv1606|M.tuberculosis_H37Rv         MT-LDPKIAARLKRNADGLVTAVVQERGSGDVLMVAWMNDEALARTLQTR
MLBr_01264|M.leprae_Br4923          MT-LDPDIAVRLKRNAEGLFTAVVQERSSGDVLMVAWMDDQALARTLETR
MAV_3180|M.avium_104                MM-LDPQIAARLKRNADGLVTAVVQERGSRDVLMVAWMDDAALARTLETR
Mflv_3606|M.gilvum_PYR-GCK          MS-LDPTIAARLKRNADGLFTAVVQERGSGDVLMVAWMDDDALARTLETR
MSMEG_3212|M.smegmatis_MC2_155      MS-LDPAIAARLKRNADGLFAAVTQERGTGKVLMVAWMDDDALARTLQTR
Mvan_2811|M.vanbaalenii_PYR-1       MSALDPAVASRLKRNADGLFTAVVQERATGQVLMVAWMDDDALARTLETR
TH_1156|M.thermoresistible__bu      VS-LDPAIAARLKRDANGLFAAVAQERGTGKVLMVAWMDDEALARTLQTR
MAB_2663c|M.abscessus_ATCC_199      MSELAPDIAARLKRDGAGLVTAVVQEHGTGTVLMVAWMNDEALALTLSTR
                                    :  * * :* ****:. **.:**.**:.:  *******:* **  **.**

MMAR_2402|M.marinum_M               EATYYSRSRGEQWVKGATSGHTQHVHSVRLDCDGDTVLLTVDQVGGACHT
MUL_1579|M.ulcerans_Agy99           EATYYSRSRGEQWVKGATSGHTQYVHSVRLDCDGDTVLLTVDQVGGACHT
Mb1632|M.bovis_AF2122/97            EATYYSRSRAEQWVKGATSGHTQHVHSVRLDCDGDAVLLTVDQVGGACHT
Rv1606|M.tuberculosis_H37Rv         EATYYSRSRAEQWVKGATSGHTQHVHSVRLDCDGDAVLLTVDQVGGACHT
MLBr_01264|M.leprae_Br4923          EANYYSRSRAEQWIKGSTSGNTQHVHSVRLDCDGDTVLLTVDQVGGACHT
MAV_3180|M.avium_104                EATYYSRSRGQQWVKGETSGHTQYVHSVRLDCDGDTVLLTVDQVGGACHT
Mflv_3606|M.gilvum_PYR-GCK          EATYFSRSRGEQWIKGRTSGHTQHVHSVRLDCDGDTVLLVVDQVGGACHT
MSMEG_3212|M.smegmatis_MC2_155      EATYFSRSRGEQWVKGATSGHTQKVHSVRLDCDGDTVLLEVDQVGGACHT
Mvan_2811|M.vanbaalenii_PYR-1       EATYFSRSRGEQWVKGLTSGHTQRVHSVRLDCDGDTVLLEVDQVGGACHT
TH_1156|M.thermoresistible__bu      RATYYSRSRRRHWVKGETSGHTQYVHSVRLDCDGDTVLLEVDQAGAACHT
MAB_2663c|M.abscessus_ATCC_199      KGTYFSRSRQRLWVKGETSGHTQYVRSVRLDCDGDTLVLEVDQSGPACHT
                                    ...*:**** . *:** ***:** *:*********:::* *** * ****

MMAR_2402|M.marinum_M               GDHTCFDATVLL------
MUL_1579|M.ulcerans_Agy99           GDHTCFDATVLL------
Mb1632|M.bovis_AF2122/97            GDHSCFDAAVLLEPDD--
Rv1606|M.tuberculosis_H37Rv         GDHSCFDAAVLLEPDD--
MLBr_01264|M.leprae_Br4923          GAHSCFDSAMLLAPQD--
MAV_3180|M.avium_104                GDHSCFDADVLLHPQD--
Mflv_3606|M.gilvum_PYR-GCK          GDHSCFDADLLLDPEA--
MSMEG_3212|M.smegmatis_MC2_155      GDHTCFDADLLLGPDE--
Mvan_2811|M.vanbaalenii_PYR-1       GDHTCFDADLLLGPDL--
TH_1156|M.thermoresistible__bu      GEHSCFDADLLLGPEEQR
MAB_2663c|M.abscessus_ATCC_199      GAHSCFDAGELLGEAP--
                                    * *:***:  **