For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTLDPDIAVRLKRNAEGLFTAVVQERSSGDVLMVAWMDDQALARTLETREANYYSRSRAEQWIKGSTSGN TQHVHSVRLDCDGDTVLLTVDQVGGACHTGAHSCFDSAMLLAPQD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01264 | hisI | - | 100% (115) | phosphoribosyl-AMP cyclohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1632 | hisI | 9e-55 | 84.35% (115) | phosphoribosyl-AMP cyclohydrolase |
| M. gilvum PYR-GCK | Mflv_3606 | - | 5e-53 | 83.33% (114) | phosphoribosyl-AMP cyclohydrolase |
| M. tuberculosis H37Rv | Rv1606 | hisI | 9e-55 | 84.35% (115) | phosphoribosyl-AMP cyclohydrolase |
| M. abscessus ATCC 19977 | MAB_2663c | - | 3e-40 | 68.81% (109) | phosphoribosyl-AMP cyclohydrolase |
| M. marinum M | MMAR_2402 | hisI | 2e-53 | 84.68% (111) | phosphoribosyl-AMP 1,6 cyclohydrolase HisI |
| M. avium 104 | MAV_3180 | hisI | 2e-52 | 82.61% (115) | phosphoribosyl-AMP cyclohydrolase |
| M. smegmatis MC2 155 | MSMEG_3212 | hisI | 1e-49 | 76.52% (115) | phosphoribosyl-AMP cyclohydrolase |
| M. thermoresistible (build 8) | TH_1156 | hisI2 | 4e-47 | 72.17% (115) | Probable phosphoribosyl-AMP 1,6 cyclohydrolase hisI |
| M. ulcerans Agy99 | MUL_1579 | hisI | 2e-52 | 82.88% (111) | phosphoribosyl-AMP cyclohydrolase |
| M. vanbaalenii PYR-1 | Mvan_2811 | hisI | 1e-49 | 80.18% (111) | phosphoribosyl-AMP cyclohydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1632|M.bovis_AF2122/97 MT-LDPKIAARLKRNADGLVTAVVQERGSGDVLMVAWMNDEALARTLQTR
Rv1606|M.tuberculosis_H37Rv MT-LDPKIAARLKRNADGLVTAVVQERGSGDVLMVAWMNDEALARTLQTR
MLBr_01264|M.leprae_Br4923 MT-LDPDIAVRLKRNAEGLFTAVVQERSSGDVLMVAWMDDQALARTLETR
MAV_3180|M.avium_104 MM-LDPQIAARLKRNADGLVTAVVQERGSRDVLMVAWMDDAALARTLETR
MMAR_2402|M.marinum_M MT-LDPNVAARLKRNAEGLFTAVVQERGSGDVLMVAWMDDDALDRTLKTR
MUL_1579|M.ulcerans_Agy99 MT-LDPNVAARLKRNADGLFTAVVQERGSGDVLMVAWMDDDALDRTLKTR
Mflv_3606|M.gilvum_PYR-GCK MS-LDPTIAARLKRNADGLFTAVVQERGSGDVLMVAWMDDDALARTLETR
MSMEG_3212|M.smegmatis_MC2_155 MS-LDPAIAARLKRNADGLFAAVTQERGTGKVLMVAWMDDDALARTLQTR
Mvan_2811|M.vanbaalenii_PYR-1 MSALDPAVASRLKRNADGLFTAVVQERATGQVLMVAWMDDDALARTLETR
TH_1156|M.thermoresistible__bu VS-LDPAIAARLKRDANGLFAAVAQERGTGKVLMVAWMDDEALARTLQTR
MAB_2663c|M.abscessus_ATCC_199 MSELAPDIAARLKRDGAGLVTAVVQEHGTGTVLMVAWMNDEALALTLSTR
: * * :* ****:. **.:**.**:.: *******:* ** **.**
Mb1632|M.bovis_AF2122/97 EATYYSRSRAEQWVKGATSGHTQHVHSVRLDCDGDAVLLTVDQVGGACHT
Rv1606|M.tuberculosis_H37Rv EATYYSRSRAEQWVKGATSGHTQHVHSVRLDCDGDAVLLTVDQVGGACHT
MLBr_01264|M.leprae_Br4923 EANYYSRSRAEQWIKGSTSGNTQHVHSVRLDCDGDTVLLTVDQVGGACHT
MAV_3180|M.avium_104 EATYYSRSRGQQWVKGETSGHTQYVHSVRLDCDGDTVLLTVDQVGGACHT
MMAR_2402|M.marinum_M EATYYSRSRGEQWVKGATSGHTQHVHSVRLDCDGDTVLLTVDQVGGACHT
MUL_1579|M.ulcerans_Agy99 EATYYSRSRGEQWVKGATSGHTQYVHSVRLDCDGDTVLLTVDQVGGACHT
Mflv_3606|M.gilvum_PYR-GCK EATYFSRSRGEQWIKGRTSGHTQHVHSVRLDCDGDTVLLVVDQVGGACHT
MSMEG_3212|M.smegmatis_MC2_155 EATYFSRSRGEQWVKGATSGHTQKVHSVRLDCDGDTVLLEVDQVGGACHT
Mvan_2811|M.vanbaalenii_PYR-1 EATYFSRSRGEQWVKGLTSGHTQRVHSVRLDCDGDTVLLEVDQVGGACHT
TH_1156|M.thermoresistible__bu RATYYSRSRRRHWVKGETSGHTQYVHSVRLDCDGDTVLLEVDQAGAACHT
MAB_2663c|M.abscessus_ATCC_199 KGTYFSRSRQRLWVKGETSGHTQYVRSVRLDCDGDTLVLEVDQSGPACHT
...*:**** . *:** ***:** *:*********:::* *** * ****
Mb1632|M.bovis_AF2122/97 GDHSCFDAAVLLEPDD--
Rv1606|M.tuberculosis_H37Rv GDHSCFDAAVLLEPDD--
MLBr_01264|M.leprae_Br4923 GAHSCFDSAMLLAPQD--
MAV_3180|M.avium_104 GDHSCFDADVLLHPQD--
MMAR_2402|M.marinum_M GDHTCFDATVLL------
MUL_1579|M.ulcerans_Agy99 GDHTCFDATVLL------
Mflv_3606|M.gilvum_PYR-GCK GDHSCFDADLLLDPEA--
MSMEG_3212|M.smegmatis_MC2_155 GDHTCFDADLLLGPDE--
Mvan_2811|M.vanbaalenii_PYR-1 GDHTCFDADLLLGPDL--
TH_1156|M.thermoresistible__bu GEHSCFDADLLLGPEEQR
MAB_2663c|M.abscessus_ATCC_199 GAHSCFDAGELLGEAP--
* *:***: **