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MRPLAIIGPTGSGKSQLALDVAERLAGEVPAEIVNADAMQLYRGMDIGTAKLSVAARRGIPHHQLDVLNV AETATVARYQQAAAADIEAIIARGHVPIVVGGSMLYVQSLLDNWSFPATDPAVRARWEECLAELGVGELH AELARRDPAAAATILPTDGRRIVRALEVIELTGQPFAASAPRIGAAQWGTAIIGLDCDTPILDDRLAVRT DSMFERGLVEEVRVLLRAGLRDGVTAARALGYAQVLAALDAGGGAELLDDAREQTYFGTRRYVRRQRSWF RRDHRVHWCDAGATGPSDRAAMVDEALRVWRHVT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1986 | miaA | - | 100% (314) | tRNA delta(2)-isopentenylpyrophosphate transferase MiaA |
| M. marinum M | MMAR_1561 | miaA_1 | e-119 | 66.24% (314) | tRNA delta(2)-isopentenylpyrophosphate transferase MiaA_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2746c | miaA | 1e-143 | 79.94% (314) | tRNA delta(2)-isopentenylpyrophosphate transferase |
| M. gilvum PYR-GCK | Mflv_3962 | miaA | 1e-127 | 73.31% (311) | tRNA delta(2)-isopentenylpyrophosphate transferase |
| M. tuberculosis H37Rv | Rv2727c | miaA | 1e-143 | 79.94% (314) | tRNA delta(2)-isopentenylpyrophosphate transferase |
| M. leprae Br4923 | MLBr_00995 | miaA | 1e-137 | 77.39% (314) | tRNA delta(2)-isopentenylpyrophosphate transferase |
| M. abscessus ATCC 19977 | MAB_3044c | - | 1e-116 | 67.74% (310) | tRNA delta(2)-isopentenylpyrophosphate transferase |
| M. avium 104 | MAV_3620 | miaA | 1e-137 | 80.39% (311) | tRNA delta(2)-isopentenylpyrophosphate transferase |
| M. smegmatis MC2 155 | MSMEG_2734 | miaA | 1e-124 | 74.12% (313) | tRNA delta(2)-isopentenylpyrophosphate transferase |
| M. thermoresistible (build 8) | TH_1518 | miaA | 1e-120 | 70.00% (320) | PROBABLE TRNA DELTA(2)-ISOPENTENYLPYROPHOSPHATE TRANSFERASE |
| M. ulcerans Agy99 | MUL_3370 | miaA | 1e-178 | 99.36% (314) | tRNA delta(2)-isopentenylpyrophosphate transferase |
| M. vanbaalenii PYR-1 | Mvan_2434 | miaA | 1e-126 | 72.61% (314) | tRNA delta(2)-isopentenylpyrophosphate transferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1986|M.marinum_M --MRPLAIIGPTGSGKSQLALDVAERLAGEVPAEIVNADAMQLYRGMDIG
MUL_3370|M.ulcerans_Agy99 --MRPLAIIGPTGSGKSQLALDVAERLAGEVPAEIVNADAMQLYRGMDIG
Mb2746c|M.bovis_AF2122/97 --MRPLAIIGPTGAGKSQLALDVAARLGARVSVEIVNADAMQLYRGMDIG
Rv2727c|M.tuberculosis_H37Rv --MRPLAIIGPTGAGKSQLALDVAARLGARVSVEIVNADAMQLYRGMDIG
MLBr_00995|M.leprae_Br4923 --MRPLAIVGPTGVGKSELALDVIERLGGQVSVEIVNADAMQLYRGMDIG
MAV_3620|M.avium_104 -----MAIIGPTGTGKSQLALDVAERLG-PLGAEIVNADAMQLYRGMDIG
Mflv_3962|M.gilvum_PYR-GCK --MRPLAVVGPTGTGKSDLALGIAEALSGEIAVEVVNADAMQLYRGMDIG
Mvan_2434|M.vanbaalenii_PYR-1 --MRPLAIVGPTGTGKSDLALAVAGLLSAEIAVEVVNADAMQLYRGMDIG
MSMEG_2734|M.smegmatis_MC2_155 -MNRPLAVIGPTGTGKSALALEFAERVGG----EIVNADAMQQYRGMDIG
TH_1518|M.thermoresistible__bu MTDRPLAIVGPTGTGKSDLAVAVAERIGG----EIVNADAMQQYRGMDIG
MAB_3044c|M.abscessus_ATCC_199 -MTRPIAVIGPTATGKSALALELAERLGG----EIVNADAMQLYRGMDIG
:*::***. *** **: . :. *:******* *******
MMAR_1986|M.marinum_M TAKLSVAARRGIPHHQLDVLNVAETATVARYQQAAAADIEAIIARGHVPI
MUL_3370|M.ulcerans_Agy99 TAKLSVAARRGIPHHQLDVLNVAETATVARYQQAAAADIEAIIARGHVPI
Mb2746c|M.bovis_AF2122/97 TAKLPVSERRGIPHHQLDVLDVTETATVARYQRAAAADIEAIAARGAVPV
Rv2727c|M.tuberculosis_H37Rv TAKLPVSERRGIPHHQLDVLDVTETATVARYQRAAAADIEAIAARGAVPV
MLBr_00995|M.leprae_Br4923 TAKLPVAARRGIPHHQLDVLDVTETATVASYQRTAAADIEAIAARGAVPV
MAV_3620|M.avium_104 TAKLPVDARRGIPHHQLDVLDVTQTATVARYQRAAAADIEAILAAGAVPI
Mflv_3962|M.gilvum_PYR-GCK TAKLTVDERRGVPHHQLDVLEVTETATVARYQQAAAADVDAIAARGALPV
Mvan_2434|M.vanbaalenii_PYR-1 TAKLTVVERHGVPHHQLDVLDVTETATVARYQQAAAADVEAIAARGALPV
MSMEG_2734|M.smegmatis_MC2_155 TAKLTVEERRGIPHHQLDVLDVVETATVARYQQAAAADIETIAARGATPV
TH_1518|M.thermoresistible__bu TAKLTVAERRGIPHHQLDVLEVTETATVARYQQAAAADVEAVIARGRVPV
MAB_3044c|M.abscessus_ATCC_199 TAKVPECERRGLVHHMLDVLDVTETATVATYQERAVATIDDIRARGHVPV
***:. *:*: ** ****:*.:***** **. *.* :: : * * *:
MMAR_1986|M.marinum_M VVGGSMLYVQSLLDNWSFPATDPAVRARWEECLAELGVGELHAELARRDP
MUL_3370|M.ulcerans_Agy99 VVGGSMLHVQSLLDNWSFPATDPAVRARWEECLAELGVGELHAELARRDP
Mb2746c|M.bovis_AF2122/97 VVGGSMLYVQSLLDDWSFPATDPSVRARWERRLAEVGVDRLHAELARRDP
Rv2727c|M.tuberculosis_H37Rv VVGGSMLYVQSLLDDWSFPATDPSVRARWERRLAEVGVDRLHAELARRDP
MLBr_00995|M.leprae_Br4923 VVGGSMLYVQSLLDDWSFPGTDPAVRVRWEQQLAEVGVVRLHAELARRDL
MAV_3620|M.avium_104 IVGGSMLYIQSLLDDWSFPATDPRVRARWERRLAEVGVGELHAELARRDP
Mflv_3962|M.gilvum_PYR-GCK IVGGSMLYVQSLLDEWSFPATDPQVRARWETRLAEVGVAALHRELAAVDA
Mvan_2434|M.vanbaalenii_PYR-1 IVGGSMLYVQSLLDQWSFPATDPRVRTRWERRLAEIGVAALHHELADVDA
MSMEG_2734|M.smegmatis_MC2_155 IVGGSMLYIQSLLDEWSFPATDPAVRAKYEARLAEIGVAALHAELARVDA
TH_1518|M.thermoresistible__bu IVGGSMMYIQALLDDWSIPATDPAVRARWEARLAEIGARALHAELARVDS
MAB_3044c|M.abscessus_ATCC_199 IVGGSMMYIQALLDDWAFPATDPQVRARWEERLAQIGVTALHAELAARDP
:*****:::*:***:*::*.*** **.::* **::*. ** *** *
MMAR_1986|M.marinum_M AAAATILPTDGRRIVRALEVIELTGQPFAASAPRIGAAQWGTAIIGLDCD
MUL_3370|M.ulcerans_Agy99 AAAATILPTDGRRIVRALEVIELTGQPFAASAPRIGAAQWGTAIIGLDCD
Mb2746c|M.bovis_AF2122/97 AAAAAILPTDARRTVRALEVVELTGQPFAASAPRIGAPRWDTVIVGLDCQ
Rv2727c|M.tuberculosis_H37Rv AAAAAILPTDARRTVRALEVVELTGQPFAASAPRIGAPRWDTVIVGLDCQ
MLBr_00995|M.leprae_Br4923 AAAAAILPTDGRRTVRALEVVELTGKPFAASAPRIGAPRWDTVIVGLDCD
MAV_3620|M.avium_104 AAAAAILPTDARRTVRALEVIELTGRPFAASAPRIGAPRWDTVIIGLDCD
Mflv_3962|M.gilvum_PYR-GCK AAAASILPTDGRRIVRALEVVELTGRPFAASAPTIGAPRWNTAIVGLDWE
Mvan_2434|M.vanbaalenii_PYR-1 AAAASILPTDGRRIVRALEVVELTGQPFAASAPTIGAPRWGTVIVGLDWD
MSMEG_2734|M.smegmatis_MC2_155 AAAASILPTDGRRIVRALEVVELTGEPFAASAPTIGAPRWDTAIIGLDWD
TH_1518|M.thermoresistible__bu AAADTILPTDGRRIVRALEVIELTGRPFAASKPPVGPPRWDTVIIGLDWA
MAB_3044c|M.abscessus_ATCC_199 AAAAIILPTDGRRTVRALEVIELTGQPFAASAPTIGPPRWDTLIVGLDWE
*** *****.** ******:****.***** * :*..:*.* *:***
MMAR_1986|M.marinum_M TPILDDRLAVRTDSMFERGLVEEVRVLLRAGLRDGVTAARALGYAQVLAA
MUL_3370|M.ulcerans_Agy99 TPILDDRLAVRTDSMFERGLVEEVRVLLRAGLRDGVTAARALGYAQVLAA
Mb2746c|M.bovis_AF2122/97 TTILDERLARRTDLMFDQGLVEEVRTLLRNGLREGVTASRALGYAQVIAA
Rv2727c|M.tuberculosis_H37Rv TTILDERLARRTDLMFDQGLVEEVRTLLRNGLREGVTASRALGYAQVIAA
MLBr_00995|M.leprae_Br4923 RTILSERLARRIDSMFGQGLVDEVRMLLRWGLRDGVTASRALGYAQVLTA
MAV_3620|M.avium_104 TTVLDERLARRTDAMFEQGLVAEVTGLLGRGLRDGVTAARALGYAQVIAA
Mflv_3962|M.gilvum_PYR-GCK TTVLDERLRRRTDTMFERGLVEEVRGLIGRGLRDGVTAARALGYAQVLAD
Mvan_2434|M.vanbaalenii_PYR-1 TTVLDERLARRTDLMFERGLVDEVVGLLGVGLREGVTAARALGYAQVLAD
MSMEG_2734|M.smegmatis_MC2_155 TAVLDERLAQRTDKMFADGLVREVVDLLERGLRDGVTAARALGYAQVLAD
TH_1518|M.thermoresistible__bu TEALDERLRQRTDKMFAAGLVDEVRGLIERGLRKGVTASRALGYAQVLAA
MAB_3044c|M.abscessus_ATCC_199 TEKLDDRIARRTDLMFEQGFVGEVEYLLSTGLRDGVTASRAIGYAQVIAA
*.:*: * * ** *:* ** *: ***.****:**:*****::
MMAR_1986|M.marinum_M LDAGG-------GAELLDDAREQTYFGTRRYVRRQRSWFRRDHRVHWCDA
MUL_3370|M.ulcerans_Agy99 LDAGG-------GAELLDDAREQTYFGTRRYVRRQRSWFRRDHRVHWCDA
Mb2746c|M.bovis_AF2122/97 LDAGA-------GADMMRAAREQTYLGTRRYVRRQRSWFRRDHRVHWLDA
Rv2727c|M.tuberculosis_H37Rv LDAGA-------GADMMRAAREQTYLGTRRYVRRQRSWFRRDHRVHWLDA
MLBr_00995|M.leprae_Br4923 LDAGG-------DADHLDEARQQTYLGHRRYARRQRSWFHRDHRVHWLDV
MAV_3620|M.avium_104 LDAGG-------GDEQLRQAREQTYAGTRRYVRRQRSWFRRDHRVRWLDA
Mflv_3962|M.gilvum_PYR-GCK LDAGG-------DGEA---AREPTFVGTRRYVRRQRSWFRRDHRITWLDG
Mvan_2434|M.vanbaalenii_PYR-1 LDAGG-------DGSA---AREPTFVGTRRYVRRQRSWFRRDHRITWLDG
MSMEG_2734|M.smegmatis_MC2_155 LDAGG-------DGSG---AREPTFIGTRRYVRRQRSWFRRDHRVVWLDG
TH_1518|M.thermoresistible__bu LDTGTGPAAQSAAGEALAEARERTFIGTRRYVRRQRSWFRRDHRIIWLDG
MAB_3044c|M.abscessus_ATCC_199 LDAGG-------GAGALAQARDLTFVGTRRYVRRQRSWFGRDHRVVWLAG
**:* **: *: * ***.******* ****: *
MMAR_1986|M.marinum_M GATGPSDRAAMVDEALRVWRHVT--------
MUL_3370|M.ulcerans_Agy99 GATGPSDRVAMVDEALRVWRHVT--------
Mb2746c|M.bovis_AF2122/97 GVASSPDRARLVDDAVRLWRHVT--------
Rv2727c|M.tuberculosis_H37Rv GVASSPDRARLVDDAVRLWRHVT--------
MLBr_00995|M.leprae_Br4923 GTV---DRVGVVDDALRVWRNAS--------
MAV_3620|M.avium_104 GACSP---PRLVDAALGAWRHVS--------
Mflv_3962|M.gilvum_PYR-GCK AAPGN------VDAVLRLWRQRRAGAPRPAD
Mvan_2434|M.vanbaalenii_PYR-1 AAGGSA---ALADKVIRIWRDVS--------
MSMEG_2734|M.smegmatis_MC2_155 ASEGL------VDDALRVWRAVS--------
TH_1518|M.thermoresistible__bu AAPDN------VERALATWRNVS--------
MAB_3044c|M.abscessus_ATCC_199 ESVETGGPEGLAGEIVSRWRLSSNT------
. : **