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TRDLPAQRTASRIYDLHSGGSLLDADESARVTGLLEEAGFVAAGPRPAWRARTDGRPTICVYCASGGDNP ADLSLAAAVGTEIGRRGWRLISGGGTIAMMGAVARAARTAGAHTTGVIPRMLLQSELADLGADELIVTDT LTQRKHLMGERADGFLTLPGGLGTLEELLECWTAASLGIHHKPVVLLDPAGHYRGLLDWLEELRQQGFVR TAAIDRLIVTTDVDSAFSNLCPSTRSAFASSGEASVSERTHAHY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1562 | - | - | 100% (255) | hypothetical protein MMAR_1562 |
| M. marinum M | MMAR_4233 | - | 1e-49 | 52.25% (178) | hypothetical protein MMAR_4233 |
| M. marinum M | MMAR_1566 | miaB | 4e-05 | 30.15% (136) | 2-methylthioadenine synthetase, MiaB |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1237 | - | 2e-47 | 51.14% (176) | hypothetical protein Mb1237 |
| M. gilvum PYR-GCK | Mflv_2184 | - | 3e-52 | 55.17% (174) | hypothetical protein Mflv_2184 |
| M. tuberculosis H37Rv | Rv1205 | - | 2e-47 | 51.14% (176) | hypothetical protein Rv1205 |
| M. leprae Br4923 | MLBr_01061 | - | 2e-48 | 52.00% (175) | hypothetical protein MLBr_01061 |
| M. abscessus ATCC 19977 | MAB_1341 | - | 6e-56 | 56.82% (176) | hypothetical protein MAB_1341 |
| M. avium 104 | MAV_1350 | - | 6e-51 | 52.30% (174) | hypothetical protein MAV_1350 |
| M. smegmatis MC2 155 | MSMEG_5087 | - | 4e-53 | 54.75% (179) | hypothetical protein MSMEG_5087 |
| M. thermoresistible (build 8) | TH_0656 | - | 2e-55 | 57.71% (175) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0956 | - | 3e-50 | 52.81% (178) | hypothetical protein MUL_0956 |
| M. vanbaalenii PYR-1 | Mvan_4511 | - | 6e-52 | 55.17% (174) | hypothetical protein Mvan_4511 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2184|M.gilvum_PYR-GCK -------------------------------------------------M
Mvan_4511|M.vanbaalenii_PYR-1 -------------------------------------------------M
MSMEG_5087|M.smegmatis_MC2_155 ----------------------------------------MVARVYVGDV
TH_0656|M.thermoresistible__bu --------------------------------------------------
Mb1237|M.bovis_AF2122/97 -----------------------------------------------MSA
Rv1205|M.tuberculosis_H37Rv -----------------------------------------------MSA
MUL_0956|M.ulcerans_Agy99 -----------------------------------------------MTA
MLBr_01061|M.leprae_Br4923 -----------------------------------------------MRS
MAV_1350|M.avium_104 -----------------------------------------------MPA
MAB_1341|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_1562|M.marinum_M MTRDLPAQRTASRIYDLHSGGSLLDADESARVTGLLEEAGFVAAGPRPAW
Mflv_2184|M.gilvum_PYR-GCK SRDPDREWAVCVYCASGPVHPELMELARKVGAGIADRGWTLVSGGGNVSA
Mvan_4511|M.vanbaalenii_PYR-1 SRDPDREWAVCVYCASGPLHPELLELARKVGEGIAERGWTLVSGGGNVSA
MSMEG_5087|M.smegmatis_MC2_155 KEGQDRQWAVCVYCASGPTHPELLELAAEVGSSIAARGWTLVSGGGNVSA
TH_0656|M.thermoresistible__bu -VNLFREWAVCVYCASGPRHPELLDLAHRVGVAIAERGWALVSGGGNVSA
Mb1237|M.bovis_AF2122/97 KIDITGDWTVAVYCAASPTHAELLELAAEVGAAIAGRGWTLVWGGGHVSA
Rv1205|M.tuberculosis_H37Rv KIDITGDWTVAVYCAASPTHAELLELAAEVGAAIAGRGWTLVWGGGHVSA
MUL_0956|M.ulcerans_Agy99 KSDEPGRWTVAVYCAAAPTHPELLELAAAVGAAIAARGWTLVWGGGHVSA
MLBr_01061|M.leprae_Br4923 DRGKPNAWAICVFCAAGPMHPELLELAAELGEAIAERGWTLVWGGGRVSA
MAV_1350|M.avium_104 ERDSSAAWAVCVYCASGPQHPELLGVAAELGEAIAERGWTLVWGGGRVSA
MAB_1341|M.abscessus_ATCC_1997 ---MNQPLSVCVYCASGPRHPELLDLATRLGTAIAERGWTLVSGGGNVSA
MMAR_1562|M.marinum_M RARTDGRPTICVYCASGGDNPADLSLAAAVGTEIGRRGWRLISGGGTIAM
::.*:**:. :. : :* :* *. *** *: *** ::
Mflv_2184|M.gilvum_PYR-GCK MGAVAAAARSHGGYTVGVIPKALVHREVADTEADELVVTDTMRERKQVME
Mvan_4511|M.vanbaalenii_PYR-1 MGVVADAARSRGGYTVGVIPKRLVHREVADTEADELVVTDTMRERKQVME
MSMEG_5087|M.smegmatis_MC2_155 MGAVAQAARAKGGHTVGVIPKALVHRELADVDAAELIVTDTMRERKREME
TH_0656|M.thermoresistible__bu MGAVAQGARSRGGYTIGVIPKALVHRELADVDADELIVTDTMRERKQVME
Mb1237|M.bovis_AF2122/97 MGAVASAARACGGWTVGVIPKMLVYRELADHDADELIVTDTMWERKQIME
Rv1205|M.tuberculosis_H37Rv MGAVASAARACGGWTVGVIPKMLVYRELADHDADELIVTDTMWERKQIME
MUL_0956|M.ulcerans_Agy99 MGAVSSAARAHGGWTVGVIPKMLVHRELADHDADELVVTETMWERKQVME
MLBr_01061|M.leprae_Br4923 MGAVASAAWTRGGRIVGVIPEMLQRREIADTYVGELIVTETMAERKQVLD
MAV_1350|M.avium_104 MGAVASAARARGGRTVGVIPTVLMRREIADADADELIVSDTLHERKQIME
MAB_1341|M.abscessus_ATCC_1997 MGAVAHAARAAGGRTIGVIPKTLVHREVADTDADELVVTTTMRERKQIME
MMAR_1562|M.marinum_M MGAVARAARTAGAHTTGVIPRMLLQSELADLGADELIVTDTLTQRKHLMG
**.*: .* : *. **** * *:** . **:*: *: :**: :
Mflv_2184|M.gilvum_PYR-GCK DRADAFLALPGGIGTLEEFFEAWTAGYLGMHTKPIVMLDTVGHYDGLLAW
Mvan_4511|M.vanbaalenii_PYR-1 DRADAFIALPGGIGTLEEFFEAWTAGYLGMHTKPIVMLDTLGHYDGLLAW
MSMEG_5087|M.smegmatis_MC2_155 HRSDAFIALPGGIGTLEEFFEAWTAGYLGMHDKPLILLDPFGHYDGLLTW
TH_0656|M.thermoresistible__bu GRADAFIALPGGIGTLEEFFEAWTAGYLGMHEKPVVMLDPDGHYAGLLAW
Mb1237|M.bovis_AF2122/97 DRSDAFIVLPGGVGTLDELFDAWTDGYLGTHDKPIVMVDPWGHFDGLRAW
Rv1205|M.tuberculosis_H37Rv DRSDAFIVLPGGVGTLDELFDAWTDGYLGTHDKPIVMVDPWGHFDGLRAW
MUL_0956|M.ulcerans_Agy99 DRANAFITLPGGVGTLDELLDVWTEGYLGMHDKSIVVLDPWGHFDGLRAW
MLBr_01061|M.leprae_Br4923 DHADAFIVLPGGLGTLDELFEAWTAGYLGMHRKPIVMLDPWGHYEGLWAW
MAV_1350|M.avium_104 DRADAFIALPGGIGTLDEVLDAWTTGFLGLHAKPIVLLDPIGHYEGLWLW
MAB_1341|M.abscessus_ATCC_1997 DRSDAFITLPGGIGTLEEVFETWTAGYLGLHDKPVVLLDPDGHYTGLLRW
MMAR_1562|M.marinum_M ERADGFLTLPGGLGTLEELLECWTAASLGIHHKPVVLLDPAGHYRGLLDW
:::.*:.****:***:*.:: ** . ** * *.::::*. **: ** *
Mflv_2184|M.gilvum_PYR-GCK LRGLVGTGYVAQDAMDSLVVVDDVDAALTACAPPLG--------------
Mvan_4511|M.vanbaalenii_PYR-1 LRGLVRTGYVAEDAMGRLIVVDDVDAALAACAPG----------------
MSMEG_5087|M.smegmatis_MC2_155 LRGLVPTGYVSQRAMDSLVVVDNVEAALEACAPE----------------
TH_0656|M.thermoresistible__bu LYGLVDTGYVDPAAMERLIVVTDIEDALAACAPSADTL------------
Mb1237|M.bovis_AF2122/97 LNGLLDTGYVSPTAMERLVVVDNVKDALRACAPS----------------
Rv1205|M.tuberculosis_H37Rv LNGLLDTGYVSPTAMERLVVVDNVKDALRACAPS----------------
MUL_0956|M.ulcerans_Agy99 LSELADTGYVSRTAMERLIVVDNLDDALQACAPG----------------
MLBr_01061|M.leprae_Br4923 LHGLIDSGYVSPVAMERLVVVDQVDAALEACMSV----------------
MAV_1350|M.avium_104 LSGLLDSGYITQAAMDRVVLVDKVGAALEACAPG----------------
MAB_1341|M.abscessus_ATCC_1997 LDELQDKGYVAAPARDRLLVHTDIAAALDACKPTD---------------
MMAR_1562|M.marinum_M LEELRQQGFVRTAAIDRLIVTTDVDSAFSNLCPSTRSAFASSGEASVSER
* * *:: * ::: .: *: .
Mflv_2184|M.gilvum_PYR-GCK -----
Mvan_4511|M.vanbaalenii_PYR-1 -----
MSMEG_5087|M.smegmatis_MC2_155 -----
TH_0656|M.thermoresistible__bu -----
Mb1237|M.bovis_AF2122/97 -----
Rv1205|M.tuberculosis_H37Rv -----
MUL_0956|M.ulcerans_Agy99 -----
MLBr_01061|M.leprae_Br4923 -----
MAV_1350|M.avium_104 -----
MAB_1341|M.abscessus_ATCC_1997 -----
MMAR_1562|M.marinum_M THAHY