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SIDDEAVTTLEDLKGDLAHRYKWTPSGGSSVDSATIEADMAALDRDGYVIWENLLSAEQCRLIREVVRPW LEHTGRNSFEGRRTQRIYSVLSRTRVCDRLADHPRVLAVLDRILMPNYLLSALQAINILPGEDAQLPHHD DGFYPIPRPRAPLAAATIWAIDDFTADNGATVVIPGSHRWGRRPPGPDDQVLPVVMSAGSCVFFVGTLWH GGGANTSTSERLAVTAQYCEPWLRPMEAYTLSISREIARAVSDDIRRMLGYSIHPPFVGAVDGLHPLRLL ESGPDS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1551 | - | - | 100% (287) | hypothetical protein MMAR_1551 |
| M. marinum M | MMAR_2314 | - | 5e-14 | 28.99% (238) | hypothetical protein MMAR_2314 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3657 | - | 1e-35 | 33.46% (272) | hypothetical protein Mb3657 |
| M. gilvum PYR-GCK | Mflv_2614 | - | 5e-06 | 31.08% (148) | phytanoyl-CoA dioxygenase |
| M. tuberculosis H37Rv | Rv3633 | - | 2e-35 | 33.46% (272) | hypothetical protein Rv3633 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2591c | - | 1e-70 | 75.93% (162) | hypothetical protein MAB_2591c |
| M. avium 104 | MAV_3990 | - | 1e-146 | 84.67% (287) | phytanoyl-CoA dioxygenase (PhyH) family protein |
| M. smegmatis MC2 155 | MSMEG_4649 | - | 1e-05 | 31.21% (157) | phytanoyl-CoA dioxygenase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3479 | - | 1e-146 | 98.80% (250) | hypothetical protein MUL_3479 |
| M. vanbaalenii PYR-1 | Mvan_3967 | - | 1e-06 | 30.95% (168) | phytanoyl-CoA dioxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3657|M.bovis_AF2122/97 -------------------------MTQSSSVERLVGEIDEFGYTVVEDV
Rv3633|M.tuberculosis_H37Rv -------------------------MTQSSSVERLVGEIDEFGYTVVEDV
MMAR_1551|M.marinum_M ----------------------MSIDDEAVTTLEDLKGDLAHRYKWTPSG
MUL_3479|M.ulcerans_Agy99 ---------------------MMTKPSQPWKTSRAIWRTATNGRQAT---
MAV_3990|M.avium_104 ----------------------MSIDDESVTTLEDLRGDLAQRYKRTPTS
MAB_2591c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2614|M.gilvum_PYR-GCK ------------MAAPLNTAAAPWLGESDFRLDDFRAQVETDTDRSDYPH
Mvan_3967|M.vanbaalenii_PYR-1 MIAVPITARLSGVAAPINTESAAWLADSDFDLDEFRAQVECDTDPADYPF
MSMEG_4649|M.smegmatis_MC2_155 ----MTSSLGSPVRSTGSTRRGAFIDESDCSLDDFRAAVARTTDAADYPH
Mb3657|M.bovis_AF2122/97 LDADSVAAYLADTRRLERE--------LPTVIAN-----STTVVKGLARP
Rv3633|M.tuberculosis_H37Rv LDADSVAAYLADTRRLERE--------LPTVIAN-----STTVVKGLARP
MMAR_1551|M.marinum_M GSSVDSATIEADMAALDRD--------GYVIWENLLSAEQCRLIREVVRP
MUL_3479|M.ulcerans_Agy99 GSSVDSATIEADMAALDRD--------GYVIWENLLSAEQCRLIQEVVRP
MAV_3990|M.avium_104 GSSVDSAIVGADMAALDRD--------GYVIWENLLSTEQCAQIRETVRP
MAB_2591c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2614|M.gilvum_PYR-GCK ADDVCGNVLVYSAPAMAR---ADRRVLQAELIRALSDGPGVVVVSEAFEP
Mvan_3967|M.vanbaalenii_PYR-1 ADDVRSNVLVYSATTLARG--SDRRGLQAELIRALDRGPGVVVFTGAFDA
MSMEG_4649|M.smegmatis_MC2_155 ATEIRSNVPVYTAAALDGTDDGRRRAVQTELIAALSDGPGVVLFENAFDP
Mb3657|M.bovis_AF2122/97 GHVPVDRVDHDWVR---IDNLLLHGTRYEALPVHPKLLPVIEGVLGRD--
Rv3633|M.tuberculosis_H37Rv GHVPVDRVDHDWVR---IDNLLLHGTRYEALPVHPKLLPVIEGVLGRD--
MMAR_1551|M.marinum_M WLEHTGRNSFEGRRTQRIYSVLSRTRVCDRLADHPRVLAVLDRILMPN--
MUL_3479|M.ulcerans_Agy99 WLEHTGRNSFEGRRTQRIYSVLSRTRVCDRLADHPRVLAVLDRILMPN--
MAV_3990|M.avium_104 WLGHTGRNSFEGRRTQRVYSVLSRTRVCDRLVDHPRVLAVLDRLLMPN--
MAB_2591c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_2614|M.gilvum_PYR-GCK EVIDRATAAFVALIEAQRTAGRAAGDHFGQPGANDRIWNAAQKLARHDPE
Mvan_3967|M.vanbaalenii_PYR-1 DVVDRASEAFFAIIEAQRKAGEAGGDHFGAPGANDRIWNAAQKLALHDPR
MSMEG_4649|M.smegmatis_MC2_155 AVVDSAGEAFTALIEQQRAAGGAAGDHFGAAGANDRVWNAAQKLALHSPR
Mb3657|M.bovis_AF2122/97 -----------------CLLSWCMTSNQL----PGAVAQRLHCDDEM---
Rv3633|M.tuberculosis_H37Rv -----------------CLLSWCMTSNQL----PGAVAQRLHCDDEM---
MMAR_1551|M.marinum_M -----------------YLLSALQAINIL----PGEDAQLPHHDDGF---
MUL_3479|M.ulcerans_Agy99 -----------------YLLSALQAINIL----PGEDAQLPHHDDGF---
MAV_3990|M.avium_104 -----------------YLLSALQAINIQ----PGEAAQLAHHDDGF---
MAB_2591c|M.abscessus_ATCC_199 ---------------------MLQVINIL----PGEQAQMLHTDDGF---
Mflv_2614|M.gilvum_PYR-GCK AFAAYYANDSLAMVCQAWLGPRYQVTSQVNVVNPGGNAQVPHRDYHLGFV
Mvan_3967|M.vanbaalenii_PYR-1 VFADYYANDALAIICQAWLGPRYQVTSQVNVVNPGGKAQVPHRDYHLGFV
MSMEG_4649|M.smegmatis_MC2_155 VYAEYYANDILALVSQAWLGPRYQVTSQVNVVNPGGAAQVPHRDYHLGFV
. . ** ** * * :
Mb3657|M.bovis_AF2122/97 -------YP--LPRPHQPLLCNALIALCDFTADNGATQVVPGSHRWPE--
Rv3633|M.tuberculosis_H37Rv -------YP--LPRPHQPLLCNALIALCDFTADNGATQVVPGSHRWPE--
MMAR_1551|M.marinum_M -------YP--IPRPRAPLAAATIWAIDDFTADNGATVVIPGSHRWGR--
MUL_3479|M.ulcerans_Agy99 -------YP--IPRPRAPLAAATIWAIDDFTADNGATVVIPGSHRWGR--
MAV_3990|M.avium_104 -------YP--VPRPRAPLAAATIWAIDDFTADNGATVLYPGSHRWGK--
MAB_2591c|M.abscessus_ATCC_199 -------YP--IPRPRAALGAATIWAIDDFTADNGATDIIAGSHLWGD--
Mflv_2614|M.gilvum_PYR-GCK PDDHLADYPTHIHRTSAVLTLQGAVAHCDMPVESGPTMLLPHSQRFTGGY
Mvan_3967|M.vanbaalenii_PYR-1 PEEHLAEYPAHIHRTSPTLTLQGAVAHCDMPVDSGPTMLLPHSQRFTGGY
MSMEG_4649|M.smegmatis_MC2_155 TPGALAAYPAHIHRLSPALTLQGAVAHCDMPVESGPTMLLPYSQTFEAGY
** : * * * *:..:.*.* : . *: :
Mb3657|M.bovis_AF2122/97 -------RPSPPYPEGKPVEINAGDALIWNGSLWHTAAANRT-DAPRPAL
Rv3633|M.tuberculosis_H37Rv -------RPSPPYPEGKPVEINAGDALIWNGSLWHTAAANRT-DAPRPAL
MMAR_1551|M.marinum_M -------RPPGPDDQVLPVVMSAGSCVFFVGTLWHGGGANTS-TSERLAV
MUL_3479|M.ulcerans_Agy99 -------RPPGPDDQVLPVVMPAGSCVFFVGTLWHGGGANTS-TSERLAV
MAV_3990|M.avium_104 -------RRPGPDDEAIPVVMPVGSCVLFVGTLWHGGGANTT-DRDRLAV
MAB_2591c|M.abscessus_ATCC_199 -------KTP-KEADRTPVVMAAGSCVFFLGTLWHGGGANQS-DSARLAL
Mflv_2614|M.gilvum_PYR-GCK IAFNRPEFLDYFAAHHVQVPLRRGDAVFFNPALYHGAGQNRSRDIRRIAN
Mvan_3967|M.vanbaalenii_PYR-1 VAFHRPGFLDYFASHHVQLPLRKGDAVFFNPALYHAAGANVSTDIRRMAN
MSMEG_4649|M.smegmatis_MC2_155 IAFYRPEFIEFFAEHHVQLPLRTGDAVFFNPALFHGAGANTSTGIRRMAN
. : : *..::: :*:* .. * : * *
Mb3657|M.bovis_AF2122/97 TINFCVGFVRQQVNQQLSIPRELVRCFEPRLQELIGYGLYAGKMG-----
Rv3633|M.tuberculosis_H37Rv TINFCVGFVRQQVNQQLSIPRELVRCFEPRLQELIGYGLYAGKMG-----
MMAR_1551|M.marinum_M TAQYCEPWLRPMEAYTLSISREIARAVSDDIRRMLGYSIHPPFVG-----
MUL_3479|M.ulcerans_Agy99 TAQYCEPWLRPMEAYILSISREIARAVSDDIRRMLGYSIHPPFVG-----
MAV_3990|M.avium_104 TAQYCQPWLRPMEAFTLSVPRDIARTVSDDIRRMLGYSIHPPFVG-----
MAB_2591c|M.abscessus_ATCC_199 TAQYCEPWLRPQEAFTLSMTRDTVRAVSEDIRRMLGYSIHPPFIG-----
Mflv_2614|M.gilvum_PYR-GCK LLQISSPFGRAMESTDR---AAMVRAVYPSLLAMSAAGRSPRDLENVVVA
Mvan_3967|M.vanbaalenii_PYR-1 LMQISSPFGRAMEAMDR---TAMVRAVYPVLRAMQAAGRPPREVENVVVA
MSMEG_4649|M.smegmatis_MC2_155 LLQISSPFGRAMEALDR---TAMIRAVYPELLAMKAAGRPEHELANVINA
: . : * * . : : . . :
Mb3657|M.bovis_AF2122/97 ---------RIDWRPPADYLDADR--HPFLDAVADRLQTSVRL-------
Rv3633|M.tuberculosis_H37Rv ---------RIDWRPPADYLDADR--HPFLDAVADRLQTSVRL-------
MMAR_1551|M.marinum_M ---------AVDGLHPLRLLESGP--DS----------------------
MUL_3479|M.ulcerans_Agy99 ---------AVDGLHPLPGLRRC---------------------------
MAV_3990|M.avium_104 ---------AVDGLHPLRLLEIEP--DA----------------------
MAB_2591c|M.abscessus_ATCC_199 ---------QVDGMHPKRLLEPGP--HPI---------------------
Mflv_2614|M.gilvum_PYR-GCK TAEGYAFPTNLDSDQPIGALAPPSQVDIVLDALARRLSPHDLDRALSAHD
Mvan_3967|M.vanbaalenii_PYR-1 TAEGYAFPTNLDSDQPVGSLAPPSQVDTVLDALARHLTEEELDIALRAQN
MSMEG_4649|M.smegmatis_MC2_155 TAEGYAFPTNLDLDQPIGSLAPPSQVDTVLEALATRRTPAELDTLLSQQD
:* * *
Mb3657|M.bovis_AF2122/97 -----
Rv3633|M.tuberculosis_H37Rv -----
MMAR_1551|M.marinum_M -----
MUL_3479|M.ulcerans_Agy99 -----
MAV_3990|M.avium_104 -----
MAB_2591c|M.abscessus_ATCC_199 -----
Mflv_2614|M.gilvum_PYR-GCK ERRTP
Mvan_3967|M.vanbaalenii_PYR-1 ERRIP
MSMEG_4649|M.smegmatis_MC2_155 ERRIP