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FDALDHVILAVRDLDDATRRYATLLSRSPSWRGDHPGWGTANTLFRLDNTYLELITPRGDGPFGQRITAQ LDERGEGPIGLAFATADLDTAHARLAANGLEPSPVSPGLGRDSETGQVRRWRSALLPETRTRAVLMIAIE HESPDRLAEAALVGSPDAVVTGIDHVVVKTSDADAAITLYRDQLGLRLALDRSFADWGMRLVFLRVGGVT IEIAQPLGDARLPARTDQVWGLSWRVPDADAARRRLAEAGFDVSEVRVGRKPGTRVVSVKDGTCDVPTLL IEPAAPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1542 | - | - | 100% (288) | hypothetical protein MMAR_1542 |
| M. marinum M | MMAR_4076 | gloA_1 | 4e-05 | 34.72% (72) | glyoxalase, GloA_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1357c | - | 3e-08 | 36.00% (100) | hypothetical protein Mb1357c |
| M. gilvum PYR-GCK | Mflv_2339 | - | 1e-06 | 33.01% (103) | glyoxalase/bleomycin resistance protein/dioxygenase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_01157 | - | 3e-05 | 29.41% (102) | hypothetical protein MLBr_01157 |
| M. abscessus ATCC 19977 | MAB_4629 | - | 4e-21 | 40.00% (130) | hypothetical protein MAB_4629 |
| M. avium 104 | MAV_1543 | mce | 2e-07 | 34.95% (103) | methylmalonyl-CoA epimerase |
| M. smegmatis MC2 155 | MSMEG_4921 | mce | 3e-05 | 31.07% (103) | methylmalonyl-CoA epimerase |
| M. thermoresistible (build 8) | TH_1535 | - | 2e-07 | 33.33% (105) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2390 | - | 1e-164 | 99.31% (288) | hypothetical protein MUL_2390 |
| M. vanbaalenii PYR-1 | Mvan_4306 | - | 4e-07 | 33.98% (103) | glyoxalase/bleomycin resistance protein/dioxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2339|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4306|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4921|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MAV_1543|M.avium_104 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
MMAR_1542|M.marinum_M MFDALDHVILAVRDLDDATRRYATLLSRSPSWRGDHPGWGTANTLFRLDN
MUL_2390|M.ulcerans_Agy99 MLDALDHVILAVRDLDNATRRYATLLSRSPSWRGDHPGWGTANTLFRLDN
MAB_4629|M.abscessus_ATCC_1997 MITELDSVLLDVPNLGEAKDAYSRLFNSS----APHP-------------
Mflv_2339|M.gilvum_PYR-GCK ---------------------------MLGYVFFMTAEQTDARPVLAT--
Mvan_4306|M.vanbaalenii_PYR-1 ----------------------------------MTAEQTDARPVLAT--
MSMEG_4921|M.smegmatis_MC2_155 ----------------------------------MTTEHVDARPALAS--
TH_1535|M.thermoresistible__bu ----------------------------------MTTDQVDARPLLPT--
MAV_1543|M.avium_104 ----------------------------------MTTDQVDARQVLAT--
Mb1357c|M.bovis_AF2122/97 ---------------------------------MMTTDQVHARHMLAT--
MLBr_01157|M.leprae_Br4923 ---------------------------------MMTTDQINTCQLLAT--
MMAR_1542|M.marinum_M TYLELITPRGDGPFGQRITAQLDERGEGPIGLAFATADLDTAHARLAANG
MUL_2390|M.ulcerans_Agy99 TYLELITPRGDGPFGQRITAQLDERGEGPIGLAFATADLDTAHARLAANG
MAB_4629|M.abscessus_ATCC_1997 -QLHLGLPR----------------WASHPGMLFRVDDLDCAARTVARRG
. : : :.
Mflv_2339|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4306|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4921|M.smegmatis_MC2_155 --------------------------------------------------
TH_1535|M.thermoresistible__bu --------------------------------------------------
MAV_1543|M.avium_104 --------------------------------------------------
Mb1357c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01157|M.leprae_Br4923 --------------------------------------------------
MMAR_1542|M.marinum_M LEPSPVSPGLGRDSETGQVRRWRSALLPETRTRAVLMIAIEHESPDRLAE
MUL_2390|M.ulcerans_Agy99 LEPSPVSPGLGRDSETGQVRRWRSALLPETRTRAVLMIAIEHESPDRLAE
MAB_4629|M.abscessus_ATCC_1997 LALT-VHGDLATGESNG------------------VTLGLSGQPP-----
Mflv_2339|M.gilvum_PYR-GCK --------ALVTAIDHVGIAVPDLDAAIKWYHDHLGMIVLHEEVNEEQGV
Mvan_4306|M.vanbaalenii_PYR-1 --------ALVTAIDHVGIAVPDLDAAIKWYHDHLGMIVLHEEVNEEQGV
MSMEG_4921|M.smegmatis_MC2_155 --------ALVTAIDHVGIAVPDLDAAAKWYHDHLGMIVLHEEINEEQGV
TH_1535|M.thermoresistible__bu --------ALVTAVDHVGIAVADLDAAIKWYHDNLGMIVLHEEVNEEQGV
MAV_1543|M.avium_104 --------ALVTAIDHVGIAVADLDAAIAWYHDHLGMILVHEEVNEEQGI
Mb1357c|M.bovis_AF2122/97 --------SLVTGLDHVGIAVADLDVAIEWYHDHLGMILVHEEINDDQGI
MLBr_01157|M.leprae_Br4923 --------TLVITIDHVGIAVADLNAAISWYHDHLGMILVHEEVNDDQGI
MMAR_1542|M.marinum_M AALVGSPDAVVTGIDHVVVKTSDADAAITLYRDQLGLRLALDRSFADWGM
MUL_2390|M.ulcerans_Agy99 AALVGSPDAVVTGIDHVVVKTSDADAAITLYRDQLGLRLALDRSFADWGM
MAB_4629|M.abscessus_ATCC_1997 --AVPQPDADSCQIDHLVLFSPNRDRIIATLCGRLGFDLRLDR-LQSWGV
: :**: : .: : ..**: : :. . *:
Mflv_2339|M.gilvum_PYR-GCK REAMLSVRGAPVGSAQIQLMAPLDETSTIAKFLDKRGPGLQQLAYRTSDI
Mvan_4306|M.vanbaalenii_PYR-1 REAMLTVRGAAVGSAQIQLMSPLDETSTIAKFIDKRGPGLQQLAYRTSDI
MSMEG_4921|M.smegmatis_MC2_155 REAMLSVRGAPKGSAQIQLLAPIDEKSTIAKFIDTRGPGLQQLAYRTSDI
TH_1535|M.thermoresistible__bu REAMLSVRGAPVGSTQIQLMAPLGPDSTIAKFLDKRGPGLQQLAYRVRDI
MAV_1543|M.avium_104 REAMLAVRGAPAGTAQLQLMAPIDDSSTIAKFLDKRGPGIQQMAMRVSDL
Mb1357c|M.bovis_AF2122/97 REALLAVPGS---AAQIQLMAPLDESSVIAKFLDKRGPGIQQLACRVSDL
MLBr_01157|M.leprae_Br4923 REAMLSAHGAPIGTTQIQLMAPINESSPIAKFLDKHGPGIQQLACRVSDL
MMAR_1542|M.marinum_M RLVFLRVGGVT-----IEIAQPLGDARLPARTDQVWG-----LSWRVPDA
MUL_2390|M.ulcerans_Agy99 RLVFLRVGGVT-----IEIAQPLGDARLPARTDQVWG-----LSWRVPDA
MAB_4629|M.abscessus_ATCC_1997 HQLFFRGAGLV-----VEVVLRDDD---PSGPDSLWG-----IAWRTADI
: :: * ::: . : . * :: *. *
Mflv_2339|M.gilvum_PYR-GCK DTLSERLREQGVRLLYDAPRRGTSNSRINFIHPKDGGGVLIELVEPASDG
Mvan_4306|M.vanbaalenii_PYR-1 DALSERLREQGVRLLYDTPRRGTADSRINFVHPKDAGGVLIELVEPAKDS
MSMEG_4921|M.smegmatis_MC2_155 DALSDRLRADGVRLLYDAPKRGTANSRINFIHPKDAGGVLIELVEPSPE-
TH_1535|M.thermoresistible__bu EAISEGLREQGIRLLYDEPRRGTANSRINFIHPKDAGGVLIELVEPAPNG
MAV_1543|M.avium_104 DTLIERLREQGVRLIYDAPRRGTANSRINFIHPKDAGGVLIELVEPAA--
Mb1357c|M.bovis_AF2122/97 DAMCRRLRSQGVRLVYETARRGTANSRINFIHPKDAGGVLIELVEPAP--
MLBr_01157|M.leprae_Br4923 DRLTKRLRAQGVRLVYDTPRQGTSNARINFIHPKDAGGVLIELVEPAS--
MMAR_1542|M.marinum_M DAARRRLAEAGFDVSEVRVGRKPGTRVVSVKDG--TCDVPTLLIEPAAPA
MUL_2390|M.ulcerans_Agy99 DAARRRLAEAGFDVSEVRVGRKPGTRVVSVKDG--TCDVPTLLIEPAAPA
MAB_4629|M.abscessus_ATCC_1997 EASHARLSGAGATLGDIRNGHKPGTRVVTVKDP--ALALPTILIEQR---
: * * : : .. :.. . : *:*
Mflv_2339|M.gilvum_PYR-GCK SGSAH
Mvan_4306|M.vanbaalenii_PYR-1 GEGSH
MSMEG_4921|M.smegmatis_MC2_155 ---EH
TH_1535|M.thermoresistible__bu --SDH
MAV_1543|M.avium_104 -----
Mb1357c|M.bovis_AF2122/97 -----
MLBr_01157|M.leprae_Br4923 -----
MMAR_1542|M.marinum_M -----
MUL_2390|M.ulcerans_Agy99 -----
MAB_4629|M.abscessus_ATCC_1997 -----