For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NTLKDELTAKVMEYEHWAKRRRFGRFGPTDRRLWVLACMDERLPINEALGIQVDSPGGHGDAHCFRNAGG LVTDDAIRSAMLSTNFFGTKEIVIVQHTQCGMLSANANDLEAYFKAKGIDTDEPILDPTLPELKLDKGGF AKWIGMTDDVDESLLKTIEVFENHPLIPDDVTISGWVWEVETRRLRPPTRDPARRARTDATARDYGITQP QPARWHLGDGGKDVATTTDPVCGMELVADRAAGHRDVDGHTLYFCSRMCLDSYDTDPARYQPAAPAV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1420 | cynT | - | 100% (278) | carbonic anhydrase, CynT |
| M. marinum M | MMAR_2546 | - | e-138 | 92.37% (249) | hypothetical protein MMAR_2546 |
| M. marinum M | MMAR_4135 | - | 7e-21 | 35.19% (162) | carbonic anhydrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1315 | - | 1e-17 | 34.97% (163) | hypothetical protein Mb1315 |
| M. gilvum PYR-GCK | Mflv_2270 | - | 4e-19 | 33.13% (163) | carbonic anhydrase |
| M. tuberculosis H37Rv | Rv1284 | - | 1e-17 | 34.97% (163) | hypothetical protein Rv1284 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4126c | - | 8e-17 | 31.48% (162) | carbonic anhydrase-related protein |
| M. avium 104 | MAV_1434 | - | 1e-19 | 33.54% (158) | carbonic anhydrase |
| M. smegmatis MC2 155 | MSMEG_4985 | - | 9e-18 | 29.45% (163) | carbonic anhydrase |
| M. thermoresistible (build 8) | TH_1318 | - | 5e-20 | 35.37% (164) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3998 | - | 5e-21 | 35.19% (162) | carbonic anhydrase |
| M. vanbaalenii PYR-1 | Mvan_4424 | - | 1e-17 | 31.90% (163) | carbonic anhydrase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2270|M.gilvum_PYR-GCK -MTVTDQYLKNNEKYAETFS---GPLPLPPSKHVAVVACMDARLDVYRIL
Mvan_4424|M.vanbaalenii_PYR-1 -MSVTDEYLKNNEEYAKTFS---GPLPLPPSRHVAVVACMDARLDVYRIL
MSMEG_4985|M.smegmatis_MC2_155 -MSVTDQYLANNEEYAKTFS---GPLPLPPSKHVAVVACMDARLDVYRIL
TH_1318|M.thermoresistible__bu -MSVTDEYLRNNEEYAKTFK---GPLPLPPSKHVAIVACMDARLDVYRAL
Mb1315|M.bovis_AF2122/97 -MTVTDDYLANNVDYASGFK---GPLPMPPSKHIAIVACMDARLDVYRML
Rv1284|M.tuberculosis_H37Rv -MTVTDDYLANNVDYASGFK---GPLPMPPSKHIAIVACMDARLDVYRML
MUL_3998|M.ulcerans_Agy99 -MTVTDDYLANNADYASGFE---GPLPMPPSKHIAILACMDARLDVYRLL
MAV_1434|M.avium_104 -MAVTDDYLAHNAGYARSFE---GPLPMPPSKHVAVVACMDARLDVYRIL
MAB_4126c|M.abscessus_ATCC_199 -MSTTDELLKNAQAYAASFDK--GELPLPPARKVAVVACMDARLNPYGLL
MMAR_1420|M.marinum_M MNTLKDELTAKVMEYEHWAKRRRFGRFGPTDRRLWVLACMDERLPINEAL
: .*: : * . *. ::: ::**** ** *
Mflv_2270|M.gilvum_PYR-GCK GLGD------GEAHVIRNAGGVVTDDEIRSLAISQRLLGTREIILIHHTD
Mvan_4424|M.vanbaalenii_PYR-1 GLKD------GEAHVIRNAGGVVTDDEIRSLAISQRLLGTREIILIHHTD
MSMEG_4985|M.smegmatis_MC2_155 GLGD------GEAHVIRNAGGVITDDEIRSLAISQRLLGTKEIILIHHTD
TH_1318|M.thermoresistible__bu GINE------GEAHVIRNAGGVITDDEIRSLAISQRLLGTREIILIHHTD
Mb1315|M.bovis_AF2122/97 GIKE------GEAHVIRNAGCVVTDDVIRSLAISQRLLGTREIILLHHTD
Rv1284|M.tuberculosis_H37Rv GIKE------GEAHVIRNAGCVVTDDVIRSLAISQRLLGTREIILLHHTD
MUL_3998|M.ulcerans_Agy99 GINE------GEAHVIRNAGGVATDDAIRSLAISQRLLGTREVVLIHHTD
MAV_1434|M.avium_104 GLRE------GEAHVIRNAGGVITDDVVRSLAISQRLLGTREIILIHHTD
MAB_4126c|M.abscessus_ATCC_199 GLHE------GDAHVIRNAGGVITEDEIRSLAISQRLLGTEEIILIHHTD
MMAR_1420|M.marinum_M GIQVDSPGGHGDAHCFRNAGGLVTDDAIRSAMLSTNFFGTKEIVIVQHTQ
*: *:** :**** : *:* :** :* .::**.*:::::**:
Mflv_2270|M.gilvum_PYR-GCK CGMLTFSDDGFK-----QQIQDETGLKPEWAAEAFQD-------------
Mvan_4424|M.vanbaalenii_PYR-1 CGMLTFTDDGFK-----QQIQDEIGIKPEWAAEAFQD-------------
MSMEG_4985|M.smegmatis_MC2_155 CGMLTFTDDEFK-----RAIQGETGIKPEWAAESFTD-------------
TH_1318|M.thermoresistible__bu CGMLTFTDDDFK-----KQIEEEIGIRPPWAPESFSD-------------
Mb1315|M.bovis_AF2122/97 CGMLTFTDDDFK-----RAIQDETGIRPTWSPESYPD-------------
Rv1284|M.tuberculosis_H37Rv CGMLTFTDDDFK-----RAIQDETGIRPTWSPESYPD-------------
MUL_3998|M.ulcerans_Agy99 CGMLTFTDDDFK-----RGIQDETGVKPPWAAEAFPD-------------
MAV_1434|M.avium_104 CGMLTFTDDDFK-----RGIQEETGIKPPWAAEAFAD-------------
MAB_4126c|M.abscessus_ATCC_199 CGMLTFTDDAFK-----QSIQDETGIKPPWSAEAFTD-------------
MMAR_1420|M.marinum_M CGMLSANANDLEAYFKAKGIDTDEPILDPTLPELKLDKGGFAKWIGMTDD
****: . : :: : *: : : .* *
Mflv_2270|M.gilvum_PYR-GCK VEEDVRQSLRRIEASPFVTKHESLRGFVFDVTTGRLNEVTL---------
Mvan_4424|M.vanbaalenii_PYR-1 PDEDVRQSLRRIDASPFVTKHESLRGFVFDVATGRLNEVTP---------
MSMEG_4985|M.smegmatis_MC2_155 LEEDVRQSLRRIEASPFVTKHESLRGFIFDVATGKLAEVTL---------
TH_1318|M.thermoresistible__bu PAEDVRQSLRRIEASPFVTLHESLRGFVFDVATGRLTEVTLD--------
Mb1315|M.bovis_AF2122/97 AVEDVRQSLRRIEVNPFVTKHTSLRGFVFDVATGKLNEVTP---------
Rv1284|M.tuberculosis_H37Rv AVEDVRQSLRRIEVNPFVTKHTSLRGFVFDVATGKLNEVTP---------
MUL_3998|M.ulcerans_Agy99 AAEDVKQSLRRIENSPFVTKHVSLRGFVFDVATGKLNEVTL---------
MAV_1434|M.avium_104 LAEDVRQSLRRIEANPFVTKHVSARGFVFDVATGKLDEVKP---------
MAB_4126c|M.abscessus_ATCC_199 LDEDVRQSLARINANPFVPRKDSVRGFVYDVTNGTLREVTAAA-------
MMAR_1420|M.marinum_M VDESLLKTIEVFENHPLIPDDVTISGWVWEVETRRLRPPTRDPARRARTD
*.: ::: :: *::. . : *::::* . * .
Mflv_2270|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4424|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4985|M.smegmatis_MC2_155 --------------------------------------------------
TH_1318|M.thermoresistible__bu --------------------------------------------------
Mb1315|M.bovis_AF2122/97 --------------------------------------------------
Rv1284|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3998|M.ulcerans_Agy99 --------------------------------------------------
MAV_1434|M.avium_104 --------------------------------------------------
MAB_4126c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1420|M.marinum_M ATARDYGITQPQPARWHLGDGGKDVATTTDPVCGMELVADRAAGHRDVDG
Mflv_2270|M.gilvum_PYR-GCK ----------------------------
Mvan_4424|M.vanbaalenii_PYR-1 ----------------------------
MSMEG_4985|M.smegmatis_MC2_155 ----------------------------
TH_1318|M.thermoresistible__bu ----------------------------
Mb1315|M.bovis_AF2122/97 ----------------------------
Rv1284|M.tuberculosis_H37Rv ----------------------------
MUL_3998|M.ulcerans_Agy99 ----------------------------
MAV_1434|M.avium_104 ----------------------------
MAB_4126c|M.abscessus_ATCC_199 ----------------------------
MMAR_1420|M.marinum_M HTLYFCSRMCLDSYDTDPARYQPAAPAV