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MSASRPNRVVLVLNSGSSSLKFQLVEPDSGMSRATGNIERIGEESSSVPDHDAALRRVFEILAEDDIDLQ SCGLVAVGHRVVHGGKDFYEPTLLNDAVIGKLDELSPLAPLHNPPAVLCIRVARALLPDVPHIAVFDTAF FHQLPPAAATYAIDRELADVWKIRRYGFHGTSHEYVSQQAAEFLGKPIGDLNQIVLHLGNGASASAVAGG RPVETSMGLTPLEGLVMGTRSGDLDPGVIGYLWRTAKLGVDEIESMLNHRSGMLGLAGERDFRRLRAMID DGDPAAELAYDVFIHRLRKYVGAYLAVLGHTDVVSFTAGIGEHDAAVRRDTLAGMAELGISLDERRNACP SGGARRISADDSPVTVLVIPTNEELAIARHCCSVLVAV
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0711 | ackA | - | 100% (388) | acetate kinase AckA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0417 | ackA | 1e-171 | 78.72% (376) | acetate kinase |
M. gilvum PYR-GCK | Mflv_0204 | - | 1e-147 | 68.42% (380) | acetate kinase |
M. tuberculosis H37Rv | Rv0409 | ackA | 1e-171 | 78.72% (376) | acetate kinase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4225c | - | 1e-129 | 63.24% (370) | acetate kinase (AckA) |
M. avium 104 | MAV_4758 | ackA | 1e-164 | 74.60% (378) | acetate kinase |
M. smegmatis MC2 155 | MSMEG_0784 | ackA | 1e-144 | 68.35% (376) | acetate kinase |
M. thermoresistible (build 8) | TH_2306 | ackA | 1e-143 | 64.47% (394) | PROBABLE ACETATE KINASE ACKA (ACETOKINASE) |
M. ulcerans Agy99 | MUL_2812 | ackA | 0.0 | 97.10% (379) | acetate kinase |
M. vanbaalenii PYR-1 | Mvan_0701 | - | 1e-150 | 69.29% (381) | acetate kinase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0711|M.marinum_M MSASRPNRVVLVLNSGSSSLKFQLVEPDSGMSRATGNIERIGEESS---- MUL_2812|M.ulcerans_Agy99 ---------MLVLNSGSSSLKFQLVEPDSGMSRATGDIERIGEKSS---- Mb0417|M.bovis_AF2122/97 -----MSSTVLVINSGSSSLKFQLVEPVAGMSRAAGIVERIGERSS---- Rv0409|M.tuberculosis_H37Rv -----MSSTVLVINSGSSSLKFQLVEPVAGMSRAAGIVERIGERSS---- MAV_4758|M.avium_104 MDGSDGARRVLVINSGSSSLKFQLVDPESGVAASTGIVERIGEESS---- Mflv_0204|M.gilvum_PYR-GCK -----MTRTVLVLNSGSSSVKYAVLEPDSGVLIADGIVERIGQEG----- Mvan_0701|M.vanbaalenii_PYR-1 -----MSRSVLVLNSGSSSVKYAVLEPDSGVLVADGIVERIGEEGAER-- MSMEG_0784|M.smegmatis_MC2_155 -------MTVLVVNSGSSSLKYAVVRPASGEFLADGIIEEIGSGA----- TH_2306|M.thermoresistible__bu ----MSERNVLVINSGSSSLKFELIEADSGTSLAEGNVERIGEDTSLAGL MAB_4225c|M.abscessus_ATCC_199 ---MSAGGSVLVLNCGSSSVKYQLIEPESGRVIAHGLVERIGEEE----- :**:*.****:*: :: . :* : * :*.**. MMAR_0711|M.marinum_M ------------SVPDHDAALRRVFEILAEDDIDLQSCGLVAVGHRVVHG MUL_2812|M.ulcerans_Agy99 ------------SVPDHDAALRRVFEILAEDDIDLQSCGLVAVGHRVVHG Mb0417|M.bovis_AF2122/97 ------------PVADHAQALHRAFKMLAEDGIDLQTCGLVAVGHRVVHG Rv0409|M.tuberculosis_H37Rv ------------PVADHAQALHRAFKMLAEDGIDLQTCGLVAVGHRVVHG MAV_4758|M.avium_104 ------------PVPDHDAALRRAFDMLAGDGVDLNTAGLVAVGHRVVHG Mflv_0204|M.gilvum_PYR-GCK ------------GAHDHAAAMRGVFDSLAADGHHLEDLGLVAVGHRVVHG Mvan_0701|M.vanbaalenii_PYR-1 ------------AVTDHAAAMQVVFDSLASDGHRLDDLGLVAVGHRVVHG MSMEG_0784|M.smegmatis_MC2_155 -------------VPDHDAALRAAFDELAAAGLHLEDLDLKAVGHRMVHG TH_2306|M.thermoresistible__bu RVGEREVRRDGEPIADHEAALRTAFDMFDEAGSNLAEMNLAAVGHRAVHG MAB_4225c|M.abscessus_ATCC_199 -------------IGNHEEALRLVFDSIDTG-------DVVVVGHRVVHG :* *:: .*. : .: .**** *** MMAR_0711|M.marinum_M GKDFYEPTLLNDAVIGKLDELSPLAPLHNPPAVLCIRVARALLPDVPHIA MUL_2812|M.ulcerans_Agy99 GKDFYEPTLLNDAVIGKLDELSPLAPLHNPPAVLCLRVARALLPDVPHIA Mb0417|M.bovis_AF2122/97 GTEFHQPTLLDDTVIGKLEELSALAPLHNPPAVLGIKVARRLLANVAHVA Rv0409|M.tuberculosis_H37Rv GTEFHQPTLLDDTVIGKLEELSALAPLHNPPAVLGIKVARRLLANVAHVA MAV_4758|M.avium_104 GNTFYRPTVLDDAVIARLHELSELAPLHNPPALLGIEVARRLLPGIAHVA Mflv_0204|M.gilvum_PYR-GCK GPDLYRPTIVDETVIDRLKELGPLAPLHNPPAVLGIEVARDALPDLPHVA Mvan_0701|M.vanbaalenii_PYR-1 GQDLYRPTVVDDATIARLKELSPLAPLHNPPAILGIEVARKALPDLPHVA MSMEG_0784|M.smegmatis_MC2_155 GKTFYKPSVVDDELIAKARELSPLAPLHNPPAIKGIEVARKLLPDLPHIA TH_2306|M.thermoresistible__bu GQTFFEPTLVTDELIAKMAELAPLAPLHNPPGLLGMTVARKLLPDVPHVA MAB_4225c|M.abscessus_ATCC_199 GQKFHEPTVLDDAVVAQIAELSSLAPLHNPAGVQGIEVARRLLPDVPQVA * :..*::: : : : **. *******..: : *** *..:.::* MMAR_0711|M.marinum_M VFDTAFFHQLPPAAATYAIDRELADVWKIRRYGFHGTSHEYVSQQAAEFL MUL_2812|M.ulcerans_Agy99 VFDTAFFHQLPPAAATYAIDRELADVWKIRRYGFHGTSHEYVSQQAADFL Mb0417|M.bovis_AF2122/97 VFDTAFFHDLPPAAATYAIDRDVADRWHIRRYGFHGTSHQYVSERAAAFL Rv0409|M.tuberculosis_H37Rv VFDTAFFHDLPPAAATYAIDRDVADRWHIRRYGFHGTSHQYVSERAAAFL MAV_4758|M.avium_104 VFDTGFFHDLPPAAATYAIDRELADRWQIRRYGFHGTSHRYVSEQAAAFL Mflv_0204|M.gilvum_PYR-GCK VFDTAFFHDLPAAAATYAIDAEVARDWNIRRYGFHGTSHQYVSEQAAAFL Mvan_0701|M.vanbaalenii_PYR-1 VFDTAFFHDLPPAAATYAIDAEVAGSWHIRRYGFHGTSHQYVSEQAAAFL MSMEG_0784|M.smegmatis_MC2_155 VFDTAFFHDLPAPASTYAIDRELAETWHIKRYGFHGTSHEYVSQQAAIFL TH_2306|M.thermoresistible__bu VFDTAFFHDLPAPAATYAIDREVAQRWDIRRYGFHGTSHQYVSEQAAVFL MAB_4225c|M.abscessus_ATCC_199 VFDTAFFFGLPPAAAIYALDRAVAERYGIRRYGFHGTSHQYVSQQAAAFL ****.**. **..*: **:* :* : *:*********.***::** ** MMAR_0711|M.marinum_M GKPIGDLNQIVLHLGNGASASAVAGGRPVETSMGLTPLEGLVMGTRSGDL MUL_2812|M.ulcerans_Agy99 SKPIGDLNQIVLHLGNGASVSAVAGGRPVETSMGLTPLEGLVMGTRSGDL Mb0417|M.bovis_AF2122/97 GRPLDGLNQIVLHLGNGASASAIARGRPVETSMGLTPLEGLVMGTRSGDL Rv0409|M.tuberculosis_H37Rv GRPLDGLNQIVLHLGNGASASAIARGRPVETSMGLTPLEGLVMGTRSGDL MAV_4758|M.avium_104 DRPLRGLKQIVLHLGNGCSASAIAGTRPLDTSMGLTPLEGLVMGTRSGDI Mflv_0204|M.gilvum_PYR-GCK DVPLESLSQIVLHLGNGASVSAIVGGRPVETSMGLTPMEGLVMGTRSGDV Mvan_0701|M.vanbaalenii_PYR-1 NVPLESLSQIVLHLGNGASASAILGGRPVETSMGLTPMEGLVMGTRSGDV MSMEG_0784|M.smegmatis_MC2_155 DRPLESLNQIVLHLGNGASASAVAGGKAVDTSMGLTPMEGLVMGTRSGDI TH_2306|M.thermoresistible__bu DRPLSSLNQIVLHLGNGASVSAIVGGRAVDTSMGLTPLEGLVMGTRPGDI MAB_4225c|M.abscessus_ATCC_199 GRGYADINQIVLHLGNGASASAILRGRAVETSMGLTPLEGLVMGTRTGDI . .:.*********.*.**: :.::*******:********.**: MMAR_0711|M.marinum_M DPGVIGYLWRTAKLGVDEIESMLNHRSGMLGLAGERDFRRLRAMIDDGDP MUL_2812|M.ulcerans_Agy99 DPGVIGYLWRTAKLGVDEIESMLNHRSGMLALAGERDFRRLRAMIDDGDP Mb0417|M.bovis_AF2122/97 DPGVISYLWRTARMGVEDIESMLNHRSGMLGLAGERDFRRLRLVIETGDR Rv0409|M.tuberculosis_H37Rv DPGVISYLWRTARMGVEDIESMLNHRSGMLGLAGERDFRRLRLVIETGDR MAV_4758|M.avium_104 DPSVVSYLCHTAGMGVDDVESMLNHRSGVVGLSGVRDFRRLRELIESGDG Mflv_0204|M.gilvum_PYR-GCK DPGVIFYLWREAGMPVEDIESMLNRRSGVRGLGGEIDFRELHRRIESGDD Mvan_0701|M.vanbaalenii_PYR-1 DPGVIFYLWRTAGMSVEDIEAMLNRRSGVRGLGGEIDFRVLHQRIESGDA MSMEG_0784|M.smegmatis_MC2_155 DPGVIMYLWRTAGMSVDDIESMLNRRSGVLGLGGASDFRKLRELIESGDE TH_2306|M.thermoresistible__bu DPGITFYLARTAGMTIDEIDELYNRRSGILGLAGANDFRELLKRIDAGDQ MAB_4225c|M.abscessus_ATCC_199 DAGIVFHLARHG-MSIDEIDTVFNRRSGMLGLCGANDFREVHRLIDAGDA *..: :* : . : ::::: : *:***: .* * *** : *: ** MMAR_0711|M.marinum_M AAELAYDVFIHRLRKYVGAYLAVLGHTDVVSFTAGIGEHDAAVRRDTLAG MUL_2812|M.ulcerans_Agy99 AAELAYDVFIHRLRKYVGAYLAVLGHTDVVSFTAGIGEHDAAVRRDALAG Mb0417|M.bovis_AF2122/97 SAQLAYEVFIHRLRKYLGAYLAVLGHTDVVSFTAGIGENDAAVRRDALAG Rv0409|M.tuberculosis_H37Rv SAQLAYEVFIHRLRKYLGAYLAVLGHTDVVSFTAGIGENDAAVRRDALAG MAV_4758|M.avium_104 AAQLAYSVFTHRLRKYIGAYLAVLGHTDVISFTAGIGENDAAVRRDAVSG Mflv_0204|M.gilvum_PYR-GCK AAELAYEVYIHRLRKYIGAYLAILGSADVITFTAGVGENDAVVRRDALTG Mvan_0701|M.vanbaalenii_PYR-1 AAQLAYDVYIHRLRKYVGAYLATLGSVDVITFTAGVGENDAAVRRDVLSG MSMEG_0784|M.smegmatis_MC2_155 HAKLAYDVYIHRLRKYIGAYMAVLGRTDVISFTAGVGENVPPVRRDALAG TH_2306|M.thermoresistible__bu AARLAYDIYIHRLRKYVGGYLALLGTTDVITFTAGVGENNPDVRRDALSG MAB_4225c|M.abscessus_ATCC_199 AAQLAYNVYVHRLRKYIGAYIATLGGADVISFTAGAGENDALLRADALAG *.***.:: ******:*.*:* ** .**::**** **: . :* *.::* MMAR_0711|M.marinum_M MAELGISLDERRNACPSGGARRISADDSPVTVLVIPTNEELAIARHCCSV MUL_2812|M.ulcerans_Agy99 MAELGISLDEGRNACASGGARRISADDSPVTVLVIPTNEELAIARHCCSV Mb0417|M.bovis_AF2122/97 LQGLGIALDQDRNLGPGHGARRISSDDSPIAVLVVPTNEELAIARDCLRV Rv0409|M.tuberculosis_H37Rv LQGLGIALDQDRNLGPGHGARRISSDDSPIAVLVVPTNEELAIARDCLRV MAV_4758|M.avium_104 MEELGIVLDERRNLPGAKGARQISADDSPITVLVVPTNEELAIARDCVRV Mflv_0204|M.gilvum_PYR-GCK LAAFGIEIDEHLNDSPGRGARRISADGAPTTVLVIPTDEELAIARACTGV Mvan_0701|M.vanbaalenii_PYR-1 LTAFGIELDEHLNASPARTARRISPDGAPITVLVVPTNEELAIARACAGV MSMEG_0784|M.smegmatis_MC2_155 LGGLGIEIDDALNSAKSDEPRLISTPDSRVTVLVVPTNEELAIARACVGV TH_2306|M.thermoresistible__bu LGALGIELDEQLNAGPTRGPRRISAAGSPTTVLVIPTNEELAIARACLSV MAB_4225c|M.abscessus_ATCC_199 LEVFGIEIDAARNQVRSGEARRISTDSSRVTVLVVPTNEELAIARAAVEA : :** :* * .* **. .: :***:**:******* . . MMAR_0711|M.marinum_M LVAV---- MUL_2812|M.ulcerans_Agy99 LAAV---- Mb0417|M.bovis_AF2122/97 LGGRRA-- Rv0409|M.tuberculosis_H37Rv LGGRRA-- MAV_4758|M.avium_104 LGG----- Mflv_0204|M.gilvum_PYR-GCK LGARPGDG Mvan_0701|M.vanbaalenii_PYR-1 LGGRLGHG MSMEG_0784|M.smegmatis_MC2_155 V------- TH_2306|M.thermoresistible__bu I------- MAB_4225c|M.abscessus_ATCC_199 I------- :