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M. marinum M MMAR_0445 (-)

annotation: transmembrane protein
coordinates: 519613 - 520782
length: 389

MSASLDDASVAPLVRKTAAWSWRLLVILAALVALLLVIKKLEIIVVPVLLALMLSALLVPVVDWLDARGL
PRGAAVSLVLLGGFSILGGILTFVISQFIVGLPDLAYQVEHSIDSSRKWLIEGPPHLRREQIDNAGNAAI
EALHNNQAKLTSGAISTAATITELLTAAVLVLFTLIFFLYGGRNIWQYVAKIIPAHVRDRAMAAGRAGYG
SLIGYVRATFLVALTDAAGVGTGLAVMGVPLALPLASIVFLGAFIPLIGALISGLLAVVVALLAKGLVYA
LLTLALLITVNQLEAHLLQPLVMGRAVSIHPLGVVLAISTGGVLAGIVGALLAVPTVAFLNNAMRVLLAE
DPIAEAQQQDQDPLALIAAQPDEPDEGTEAEAGADQTRP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0445--100% (389)transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0211-1e-16180.22% (364) transmembrane protein
M. gilvum PYR-GCKMflv_0457-1e-13363.51% (370) hypothetical protein Mflv_0457
M. tuberculosis H37RvRv0205-1e-16180.22% (364) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4521c-1e-10853.68% (380) hypothetical protein MAB_4521c
M. avium 104MAV_4969-1e-16576.90% (381) hypothetical protein MAV_4969
M. smegmatis MC2 155MSMEG_0249-1e-14168.92% (370) integral membrane protein
M. thermoresistible (build 8)TH_1309-1e-9363.47% (271) integral membrane protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0195-1e-13564.88% (373) hypothetical protein Mvan_0195

CLUSTAL 2.0.9 multiple sequence alignment


Mb0211|M.bovis_AF2122/97            -----MSASLDDASVAPLVRKTAAWAWRFLVILAAMVALLWVLNKFEVIV
Rv0205|M.tuberculosis_H37Rv         -----MSASLDDASVAPLVRKTAAWAWRFLVILAAMVALLWVLNKFEVIV
MMAR_0445|M.marinum_M               -----MSASLDDASVAPLVRKTAAWSWRLLVILAALVALLLVIKKLEIIV
MAV_4969|M.avium_104                -----MSANVDDASVEPIVRKTAAWAWRLLVILAAALALFWVLAKLEVIV
Mflv_0457|M.gilvum_PYR-GCK          MSARPPFDSIADDSVTPLVRMAAAWSWRLLVIFAAIVTLLWLVLRLEILV
Mvan_0195|M.vanbaalenii_PYR-1       MSAGPCFDTFADDSVSPLVRKAAAWSWRLLLILGAIVTLLWLILRLEIIV
MSMEG_0249|M.smegmatis_MC2_155      ----MALDPVADEAVSPLVRKAAAWSWRLLIIGGAIVALLWLIKRLEILF
TH_1309|M.thermoresistible__bu      --------------------------------------------------
MAB_4521c|M.abscessus_ATCC_199      -----MTHADAAESVHPYVRKGAAWAWRLLVLLAFGLTVLWLFWHLKTIT
                                                                                      

Mb0211|M.bovis_AF2122/97            VPVLLALMLSALLVPPVDWLDSRGLPRAVAVTLVLLSGFAVLGGILTFVV
Rv0205|M.tuberculosis_H37Rv         VPVLLALMLSALLVPPVDWLDSRGLPHAVAVTLVLLSGFAVLGGILTFVV
MMAR_0445|M.marinum_M               VPVLLALMLSALLVPVVDWLDARGLPRGAAVSLVLLGGFSILGGILTFVI
MAV_4969|M.avium_104                VPVLVALLLSALLVPVVDWLDRHGLPRGGAVALVLLGGFAILGGILAFVV
Mflv_0457|M.gilvum_PYR-GCK          VPVALATIIAALLLPVVDFLDRRGAPRGGAVALVLLTGFALFGGLLAFVV
Mvan_0195|M.vanbaalenii_PYR-1       VPVALATILAALLLPVVDFLDRRGAPRGGAVALVLLSGFALFGGLLAFVI
MSMEG_0249|M.smegmatis_MC2_155      VPVALATMVAALLLPAVDFMDRRGAPRGSAVALVLLGGIAVVGGILTFVV
TH_1309|M.thermoresistible__bu      --------------------------------------------------
MAB_4521c|M.abscessus_ATCC_199      IPLLLALMGSALLVPTVNFLQRHKIPRSLAVVVVLLTGTAAIVGILTFVV
                                                                                      

Mb0211|M.bovis_AF2122/97            SQFIAGLPHLVTEVERSIDSARRWLIEGPAHLRGEQIDNAGNAAIEALRN
Rv0205|M.tuberculosis_H37Rv         SQFIAGLPHLVTEVERSIDSARRWLIEGPAHLRGEQIDNAGNAAIEALRN
MMAR_0445|M.marinum_M               SQFIVGLPDLAYQVEHSIDSSRKWLIEGPPHLRREQIDNAGNAAIEALHN
MAV_4969|M.avium_104                LQFIDGLPGLTEQVTQSIESTRRWLINGPAHLRSEQIDSAGNAAIEALHN
Mflv_0457|M.gilvum_PYR-GCK          TQFVEGAPDLVGQVSTSIEGVGKWLTDGPLQVSDQQINQARDTAIEALQS
Mvan_0195|M.vanbaalenii_PYR-1       TQFVEGAPALVGQVTTSIEGVGTWLTDGPLDVSPQQINQLRDAAIEALRS
MSMEG_0249|M.smegmatis_MC2_155      TQFIQGAPDLVEQMTRSIDGVRNWLIDGPLHLSKEQIDSAGNTAIEALQR
TH_1309|M.thermoresistible__bu      --------------------VQDWLIEGPFKLSRDQIDQAGTAAIEALRN
MAB_4521c|M.abscessus_ATCC_199      DQFIKGLPDLSAQLTNSIESLKNWAIHSRFHISEDQIGKAGDALVNTIKD
                                                           *  ..  .:  :**..   : ::::: 

Mb0211|M.bovis_AF2122/97            NQAKLTSGALSTAATITELVTAAVLVLFTLIFFLYGGRSIWQYVTKAFPA
Rv0205|M.tuberculosis_H37Rv         NQAKLTSGALSTAATITELVTAAVLVLFTLIFFLYGGRSIWQYVTKAFPA
MMAR_0445|M.marinum_M               NQAKLTSGAISTAATITELLTAAVLVLFTLIFFLYGGRNIWQYVAKIIPA
MAV_4969|M.avium_104                NQAKLTSGALSTAATVTELVTAAVLVLFTLIFFLYGGRNIWRYVVQIVPA
Mflv_0457|M.gilvum_PYR-GCK          NQEKLTSGALSTAGTLTEIVTGALLVFFTLIFLLHGGRNIFSFVTRIFPS
Mvan_0195|M.vanbaalenii_PYR-1       NQEKLTSGALSTAGTVTEIVTGALLVLFTLIFLLHGGRNIFAFVTKMFPV
MSMEG_0249|M.smegmatis_MC2_155      NQEKVTTGALSTAGTLTELLTGAVLTLFTLIFLLQGGRNIFAFVTKAFPE
TH_1309|M.thermoresistible__bu      NQERLTSGALSTATTITEILAGAVLALFTLIFLLHGGRNIFAFITLPFPP
MAB_4521c|M.abscessus_ATCC_199      NQGRVTSGALATATTVTEIITGAVLTLFTTIFFLYGGKEIWEFVTRIFPT
                                    ** ::*:**::** *:**:::.*:*.:** **:* **:.*: ::.  .* 

Mb0211|M.bovis_AF2122/97            SVRDRVRAAGRAGYASLIGYARATFLVALTDAAGVGAGLAVMGVPLALPL
Rv0205|M.tuberculosis_H37Rv         SVRDRVRAAGRAGYASLIGYARATFLVALTDAAGVGAGLAVMGVPLALPL
MMAR_0445|M.marinum_M               HVRDRAMAAGRAGYGSLIGYVRATFLVALTDAAGVGTGLAVMGVPLALPL
MAV_4969|M.avium_104                HARERVHEAGSAGYGSLIGYVRATFLVALTDAAGVGAGLAIMGIPLALPL
Mflv_0457|M.gilvum_PYR-GCK          HVRGRVHDAGRAGFRSLIGYVRATFLVAAVDAIGIGVGLAIMGVPLALPL
Mvan_0195|M.vanbaalenii_PYR-1       HVRDRVRDAGRAGFRSLIGYIRATFLVALVDATGIGVGLAIMGVPLALPL
MSMEG_0249|M.smegmatis_MC2_155      DVRERVRDAGRAGFHSLIGYVRATFLVALVDAIGIGTGLAIMGIPLALPL
TH_1309|M.thermoresistible__bu      EVRERVRDAGRAGFRSLVGFVRATFAVALVDAIGIGAGLAILGVPLALPL
MAB_4521c|M.abscessus_ATCC_199      AVRPRVRRAGVLGFGSLIGYVRATVAVALVDAIGIGVGLAAFSVPLALPL
                                     .* *.  **  *: **:*: ***. ** .** *:*.*** :.:******

Mb0211|M.bovis_AF2122/97            ASLVFFGAFIPLIGAVVAGFLAVVVALLAKGIGYALITVGLLIAVNQLEA
Rv0205|M.tuberculosis_H37Rv         ASLVFFGAFIPLIGAVVAGFLAVVVALLAKGIGYALITVGLLIAVNQLEA
MMAR_0445|M.marinum_M               ASIVFLGAFIPLIGALISGLLAVVVALLAKGLVYALLTLALLITVNQLEA
MAV_4969|M.avium_104                ASLVFLGAFIPLVGAVVAGFLAVVVALLAKGIVYALITLGLLVAVNQIEA
Mflv_0457|M.gilvum_PYR-GCK          ASLVFMGAFVPLVGAVVTGFLAVIVALIAKGWIYALITLGLIIAVQQLEG
Mvan_0195|M.vanbaalenii_PYR-1       ASLVFLGAFIPLVGAVVTGFLAVIVALIAKGWIYALITLGLIIAVQQLEG
MSMEG_0249|M.smegmatis_MC2_155      ASLVFLGAFVPLVGAVIAGFLAVVVALLAKGLVYALITLGLIIAVQQLEG
TH_1309|M.thermoresistible__bu      ASLVFLGAFIPLIGAFVTGFLAVVVALIAKGFIYALITLGLIVAVQQLEG
MAB_4521c|M.abscessus_ATCC_199      ASLVFLGAFIPIIGAAISGFVAVFIALITKGAFTAAMILVIVIVVMQVEG
                                    **:**:***:*::** ::*::**.:**::**   * : : :::.* *:*.

Mb0211|M.bovis_AF2122/97            HLLQPLVMGRAVSIHPLAVVLAIAAGGVLAGVVGALLAVPTAAFFNNAVQ
Rv0205|M.tuberculosis_H37Rv         HLLQPLVMGRAVSIHPLAVVLAIAAGGVLAGVVGALLAVPTVAFFNNAVQ
MMAR_0445|M.marinum_M               HLLQPLVMGRAVSIHPLGVVLAISTGGVLAGIVGALLAVPTVAFLNNAMR
MAV_4969|M.avium_104                HLLQPLVMGRAVSIHPLAVVLAISTGGVLAGIVGALLAVPTVAFLNNAFQ
Mflv_0457|M.gilvum_PYR-GCK          HVLQPLVMGRAVAIHPLAIVLAIAGGAVLAGIVGALLAVPVLAFLNSAIR
Mvan_0195|M.vanbaalenii_PYR-1       HVLQPLVMGRAVAIHPLAIVLAIAGGGVLAGIVGALLAVPALAFVNSAMR
MSMEG_0249|M.smegmatis_MC2_155      HVLQPLVMGRAVSIHPLAVVLAIAGGGVLAGIVGALLAVPAVAFLNSATR
TH_1309|M.thermoresistible__bu      HVLQPLIMGYAVRIHPLAIVLAIGAGGVLAGIIGALLAVPIMAFVNSAGR
MAB_4521c|M.abscessus_ATCC_199      HVLQPLIMGHAVQIHALAVVLAIAAGGVLGGIIGALLAVPTVAVLNTAIR
                                    *:****:** ** **.*.:****. *.**.*::*******  *..*.* :

Mb0211|M.bovis_AF2122/97            VLLG----GNPFADVADV---SSDHLTEV---------------------
Rv0205|M.tuberculosis_H37Rv         VLLG----GNPFADVADV---SSDHLTEV---------------------
MMAR_0445|M.marinum_M               VLLA----EDPIAEAQQQ---DQDPLALIAAQPDEPDEGTEAEAGADQTR
MAV_4969|M.avium_104                VLLA----PNPSAEAVKQEEESDEQNTILQAEPDKPENGSG---------
Mflv_0457|M.gilvum_PYR-GCK          VLTA----DDPVAEEQAME---EQDEGLVNAEPDDVEARE----------
Mvan_0195|M.vanbaalenii_PYR-1       VLLA----EDPAAEEAAME---AEDGPVVRAEPDDVETPQE---------
MSMEG_0249|M.smegmatis_MC2_155      VLLA----RDPHAEEEALV---AESTTIIAAESDDLPERE----------
TH_1309|M.thermoresistible__bu      VLLA----PDPAREEAELE---AEEGPLIGAEPDPVDDAEPVPAGDAEPA
MAB_4521c|M.abscessus_ATCC_199      ALIEPFDADDPYLREGEEEAEVLDPEMVPDGGPSALGAKPGNGVPELGPA
                                    .*       :*            :                          

Mb0211|M.bovis_AF2122/97            ---------------
Rv0205|M.tuberculosis_H37Rv         ---------------
MMAR_0445|M.marinum_M               P--------------
MAV_4969|M.avium_104                ---------------
Mflv_0457|M.gilvum_PYR-GCK          ---------------
Mvan_0195|M.vanbaalenii_PYR-1       ---------------
MSMEG_0249|M.smegmatis_MC2_155      ---------------
TH_1309|M.thermoresistible__bu      PAGDAEPDPPERAGD
MAB_4521c|M.abscessus_ATCC_199      PPKD-----------