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THADAAESVHPYVRKGAAWAWRLLVLLAFGLTVLWLFWHLKTITIPLLLALMGSALLVPTVNFLQRHKIP RSLAVVVVLLTGTAAIVGILTFVVDQFIKGLPDLSAQLTNSIESLKNWAIHSRFHISEDQIGKAGDALVN TIKDNQGRVTSGALATATTVTEIITGAVLTLFTTIFFLYGGKEIWEFVTRIFPTAVRPRVRRAGVLGFGS LIGYVRATVAVALVDAIGIGVGLAAFSVPLALPLASLVFLGAFIPIIGAAISGFVAVFIALITKGAFTAA MILVIVIVVMQVEGHVLQPLIMGHAVQIHALAVVLAIAAGGVLGGIIGALLAVPTVAVLNTAIRALIEPF DADDPYLREGEEEAEVLDPEMVPDGGPSALGAKPGNGVPELGPAPPKD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4521c | - | - | 100% (399) | hypothetical protein MAB_4521c |
| M. abscessus ATCC 19977 | MAB_0549c | - | 2e-05 | 26.67% (225) | putative heme/hemin ABC transporter, permease protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0211 | - | 1e-109 | 57.35% (340) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0457 | - | 1e-107 | 55.96% (361) | hypothetical protein Mflv_0457 |
| M. tuberculosis H37Rv | Rv0205 | - | 1e-108 | 57.35% (340) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0445 | - | 1e-107 | 53.68% (380) | transmembrane protein |
| M. avium 104 | MAV_4969 | - | 1e-112 | 54.74% (380) | hypothetical protein MAV_4969 |
| M. smegmatis MC2 155 | MSMEG_0249 | - | 1e-111 | 57.69% (364) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1309 | - | 4e-82 | 56.60% (288) | integral membrane protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0195 | - | 1e-108 | 56.23% (361) | hypothetical protein Mvan_0195 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0457|M.gilvum_PYR-GCK MSARPPFDSIADDSVTPLVRMAAAWSWRLLVIFAAIVTLLWLVLRLEILV
Mvan_0195|M.vanbaalenii_PYR-1 MSAGPCFDTFADDSVSPLVRKAAAWSWRLLLILGAIVTLLWLILRLEIIV
MSMEG_0249|M.smegmatis_MC2_155 ----MALDPVADEAVSPLVRKAAAWSWRLLIIGGAIVALLWLIKRLEILF
TH_1309|M.thermoresistible__bu --------------------------------------------------
Mb0211|M.bovis_AF2122/97 -----MSASLDDASVAPLVRKTAAWAWRFLVILAAMVALLWVLNKFEVIV
Rv0205|M.tuberculosis_H37Rv -----MSASLDDASVAPLVRKTAAWAWRFLVILAAMVALLWVLNKFEVIV
MMAR_0445|M.marinum_M -----MSASLDDASVAPLVRKTAAWSWRLLVILAALVALLLVIKKLEIIV
MAV_4969|M.avium_104 -----MSANVDDASVEPIVRKTAAWAWRLLVILAAALALFWVLAKLEVIV
MAB_4521c|M.abscessus_ATCC_199 -----MTHADAAESVHPYVRKGAAWAWRLLVLLAFGLTVLWLFWHLKTIT
Mflv_0457|M.gilvum_PYR-GCK VPVALATIIAALLLPVVDFLDRRGAPRGGAVALVLLTGFALFGGLLAFVV
Mvan_0195|M.vanbaalenii_PYR-1 VPVALATILAALLLPVVDFLDRRGAPRGGAVALVLLSGFALFGGLLAFVI
MSMEG_0249|M.smegmatis_MC2_155 VPVALATMVAALLLPAVDFMDRRGAPRGSAVALVLLGGIAVVGGILTFVV
TH_1309|M.thermoresistible__bu --------------------------------------------------
Mb0211|M.bovis_AF2122/97 VPVLLALMLSALLVPPVDWLDSRGLPRAVAVTLVLLSGFAVLGGILTFVV
Rv0205|M.tuberculosis_H37Rv VPVLLALMLSALLVPPVDWLDSRGLPHAVAVTLVLLSGFAVLGGILTFVV
MMAR_0445|M.marinum_M VPVLLALMLSALLVPVVDWLDARGLPRGAAVSLVLLGGFSILGGILTFVI
MAV_4969|M.avium_104 VPVLVALLLSALLVPVVDWLDRHGLPRGGAVALVLLGGFAILGGILAFVV
MAB_4521c|M.abscessus_ATCC_199 IPLLLALMGSALLVPTVNFLQRHKIPRSLAVVVVLLTGTAAIVGILTFVV
Mflv_0457|M.gilvum_PYR-GCK TQFVEGAPDLVGQVSTSIEGVGKWLTDGPLQVSDQQINQARDTAIEALQS
Mvan_0195|M.vanbaalenii_PYR-1 TQFVEGAPALVGQVTTSIEGVGTWLTDGPLDVSPQQINQLRDAAIEALRS
MSMEG_0249|M.smegmatis_MC2_155 TQFIQGAPDLVEQMTRSIDGVRNWLIDGPLHLSKEQIDSAGNTAIEALQR
TH_1309|M.thermoresistible__bu --------------------VQDWLIEGPFKLSRDQIDQAGTAAIEALRN
Mb0211|M.bovis_AF2122/97 SQFIAGLPHLVTEVERSIDSARRWLIEGPAHLRGEQIDNAGNAAIEALRN
Rv0205|M.tuberculosis_H37Rv SQFIAGLPHLVTEVERSIDSARRWLIEGPAHLRGEQIDNAGNAAIEALRN
MMAR_0445|M.marinum_M SQFIVGLPDLAYQVEHSIDSSRKWLIEGPPHLRREQIDNAGNAAIEALHN
MAV_4969|M.avium_104 LQFIDGLPGLTEQVTQSIESTRRWLINGPAHLRSEQIDSAGNAAIEALHN
MAB_4521c|M.abscessus_ATCC_199 DQFIKGLPDLSAQLTNSIESLKNWAIHSRFHISEDQIGKAGDALVNTIKD
* .. .: :**.. : :::::
Mflv_0457|M.gilvum_PYR-GCK NQEKLTSGALSTAGTLTEIVTGALLVFFTLIFLLHGGRNIFSFVTRIFPS
Mvan_0195|M.vanbaalenii_PYR-1 NQEKLTSGALSTAGTVTEIVTGALLVLFTLIFLLHGGRNIFAFVTKMFPV
MSMEG_0249|M.smegmatis_MC2_155 NQEKVTTGALSTAGTLTELLTGAVLTLFTLIFLLQGGRNIFAFVTKAFPE
TH_1309|M.thermoresistible__bu NQERLTSGALSTATTITEILAGAVLALFTLIFLLHGGRNIFAFITLPFPP
Mb0211|M.bovis_AF2122/97 NQAKLTSGALSTAATITELVTAAVLVLFTLIFFLYGGRSIWQYVTKAFPA
Rv0205|M.tuberculosis_H37Rv NQAKLTSGALSTAATITELVTAAVLVLFTLIFFLYGGRSIWQYVTKAFPA
MMAR_0445|M.marinum_M NQAKLTSGAISTAATITELLTAAVLVLFTLIFFLYGGRNIWQYVAKIIPA
MAV_4969|M.avium_104 NQAKLTSGALSTAATVTELVTAAVLVLFTLIFFLYGGRNIWRYVVQIVPA
MAB_4521c|M.abscessus_ATCC_199 NQGRVTSGALATATTVTEIITGAVLTLFTTIFFLYGGKEIWEFVTRIFPT
** ::*:**::** *:**:::.*:*.:** **:* **:.*: ::. .*
Mflv_0457|M.gilvum_PYR-GCK HVRGRVHDAGRAGFRSLIGYVRATFLVAAVDAIGIGVGLAIMGVPLALPL
Mvan_0195|M.vanbaalenii_PYR-1 HVRDRVRDAGRAGFRSLIGYIRATFLVALVDATGIGVGLAIMGVPLALPL
MSMEG_0249|M.smegmatis_MC2_155 DVRERVRDAGRAGFHSLIGYVRATFLVALVDAIGIGTGLAIMGIPLALPL
TH_1309|M.thermoresistible__bu EVRERVRDAGRAGFRSLVGFVRATFAVALVDAIGIGAGLAILGVPLALPL
Mb0211|M.bovis_AF2122/97 SVRDRVRAAGRAGYASLIGYARATFLVALTDAAGVGAGLAVMGVPLALPL
Rv0205|M.tuberculosis_H37Rv SVRDRVRAAGRAGYASLIGYARATFLVALTDAAGVGAGLAVMGVPLALPL
MMAR_0445|M.marinum_M HVRDRAMAAGRAGYGSLIGYVRATFLVALTDAAGVGTGLAVMGVPLALPL
MAV_4969|M.avium_104 HARERVHEAGSAGYGSLIGYVRATFLVALTDAAGVGAGLAIMGIPLALPL
MAB_4521c|M.abscessus_ATCC_199 AVRPRVRRAGVLGFGSLIGYVRATVAVALVDAIGIGVGLAAFSVPLALPL
.* *. ** *: **:*: ***. ** .** *:*.*** :.:******
Mflv_0457|M.gilvum_PYR-GCK ASLVFMGAFVPLVGAVVTGFLAVIVALIAKGWIYALITLGLIIAVQQLEG
Mvan_0195|M.vanbaalenii_PYR-1 ASLVFLGAFIPLVGAVVTGFLAVIVALIAKGWIYALITLGLIIAVQQLEG
MSMEG_0249|M.smegmatis_MC2_155 ASLVFLGAFVPLVGAVIAGFLAVVVALLAKGLVYALITLGLIIAVQQLEG
TH_1309|M.thermoresistible__bu ASLVFLGAFIPLIGAFVTGFLAVVVALIAKGFIYALITLGLIVAVQQLEG
Mb0211|M.bovis_AF2122/97 ASLVFFGAFIPLIGAVVAGFLAVVVALLAKGIGYALITVGLLIAVNQLEA
Rv0205|M.tuberculosis_H37Rv ASLVFFGAFIPLIGAVVAGFLAVVVALLAKGIGYALITVGLLIAVNQLEA
MMAR_0445|M.marinum_M ASIVFLGAFIPLIGALISGLLAVVVALLAKGLVYALLTLALLITVNQLEA
MAV_4969|M.avium_104 ASLVFLGAFIPLVGAVVAGFLAVVVALLAKGIVYALITLGLLVAVNQIEA
MAB_4521c|M.abscessus_ATCC_199 ASLVFLGAFIPIIGAAISGFVAVFIALITKGAFTAAMILVIVIVVMQVEG
**:**:***:*::** ::*::**.:**::** * : : :::.* *:*.
Mflv_0457|M.gilvum_PYR-GCK HVLQPLVMGRAVAIHPLAIVLAIAGGAVLAGIVGALLAVPVLAFLNSAIR
Mvan_0195|M.vanbaalenii_PYR-1 HVLQPLVMGRAVAIHPLAIVLAIAGGGVLAGIVGALLAVPALAFVNSAMR
MSMEG_0249|M.smegmatis_MC2_155 HVLQPLVMGRAVSIHPLAVVLAIAGGGVLAGIVGALLAVPAVAFLNSATR
TH_1309|M.thermoresistible__bu HVLQPLIMGYAVRIHPLAIVLAIGAGGVLAGIIGALLAVPIMAFVNSAGR
Mb0211|M.bovis_AF2122/97 HLLQPLVMGRAVSIHPLAVVLAIAAGGVLAGVVGALLAVPTAAFFNNAVQ
Rv0205|M.tuberculosis_H37Rv HLLQPLVMGRAVSIHPLAVVLAIAAGGVLAGVVGALLAVPTVAFFNNAVQ
MMAR_0445|M.marinum_M HLLQPLVMGRAVSIHPLGVVLAISTGGVLAGIVGALLAVPTVAFLNNAMR
MAV_4969|M.avium_104 HLLQPLVMGRAVSIHPLAVVLAISTGGVLAGIVGALLAVPTVAFLNNAFQ
MAB_4521c|M.abscessus_ATCC_199 HVLQPLIMGHAVQIHALAVVLAIAAGGVLGGIIGALLAVPTVAVLNTAIR
*:****:** ** **.*.:****. *.**.*::******* *..*.* :
Mflv_0457|M.gilvum_PYR-GCK VLTA----DDPVAEEQAME---EQDEGLVNAEPDDVEARE----------
Mvan_0195|M.vanbaalenii_PYR-1 VLLA----EDPAAEEAAME---AEDGPVVRAEPDDVETPQE---------
MSMEG_0249|M.smegmatis_MC2_155 VLLA----RDPHAEEEALV---AESTTIIAAESDDLPERE----------
TH_1309|M.thermoresistible__bu VLLA----PDPAREEAELE---AEEGPLIGAEPDPVDDAEPVPAGDAEPA
Mb0211|M.bovis_AF2122/97 VLLG----GNPFADVADV---SSDHLTEV---------------------
Rv0205|M.tuberculosis_H37Rv VLLG----GNPFADVADV---SSDHLTEV---------------------
MMAR_0445|M.marinum_M VLLA----EDPIAEAQQQ---DQDPLALIAAQPDEPDEGTEAEAGADQTR
MAV_4969|M.avium_104 VLLA----PNPSAEAVKQEEESDEQNTILQAEPDKPENGSG---------
MAB_4521c|M.abscessus_ATCC_199 ALIEPFDADDPYLREGEEEAEVLDPEMVPDGGPSALGAKPGNGVPELGPA
.* :* :
Mflv_0457|M.gilvum_PYR-GCK ---------------
Mvan_0195|M.vanbaalenii_PYR-1 ---------------
MSMEG_0249|M.smegmatis_MC2_155 ---------------
TH_1309|M.thermoresistible__bu PAGDAEPDPPERAGD
Mb0211|M.bovis_AF2122/97 ---------------
Rv0205|M.tuberculosis_H37Rv ---------------
MMAR_0445|M.marinum_M P--------------
MAV_4969|M.avium_104 ---------------
MAB_4521c|M.abscessus_ATCC_199 PPKD-----------