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MFTQTLTQTLAKRVLGSGLVDLLTGPHGIDRYTELVEPTWTLGEARAKLIDVRRTTPRSVTLTLAPNDTF RSAMAAGTGPMAGQYVNLTVDIDGRRHTRCYSPANAEGSETLELTIGRHDGGLVSTYLCDHARRGMVVGL AGVGGDFVLPQRRPRRILFVSGGSGITPVLAMLRTLVAQHHLHIHGAEIAFIHYARNPAEACYRAELAAL PGVRVLHGYTQSGGGDLVGRFGPDHLAAAMDAPDAVFVCGPTTLVDAVRENCENVFTESFVPAPIEAPAQ PSGGRVRFADSGIDVVDDGRSLLEQAESAGLAPENGCRMGICHTCTRRKTSGTVRNLVTGAVSVAPDEDV QVCVSVPVGDVDLSL
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0335 | - | - | 100% (365) | flavodoxin oxidoreductase |
M. marinum M | MMAR_1314 | - | 3e-36 | 31.58% (361) | oxidoreductase |
M. marinum M | MMAR_2865 | - | 2e-14 | 35.68% (199) | oxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3259c | - | 4e-38 | 33.70% (362) | oxidoreductase |
M. gilvum PYR-GCK | Mflv_4815 | - | 1e-124 | 63.24% (370) | oxidoreductase FAD-binding subunit |
M. tuberculosis H37Rv | Rv3230c | - | 5e-39 | 33.98% (362) | oxidoreductase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1588c | - | 3e-71 | 46.28% (363) | putative oxidoreductase |
M. avium 104 | MAV_5168 | - | 1e-169 | 79.57% (372) | oxidoreductase FAD-binding subunit |
M. smegmatis MC2 155 | MSMEG_1742 | - | 1e-129 | 63.56% (376) | oxidoreductase |
M. thermoresistible (build 8) | TH_2872 | - | 7e-41 | 33.43% (359) | PUTATIVE 2Fe-2S iron-sulfur cluster binding domain protein |
M. ulcerans Agy99 | MUL_4786 | - | 0.0 | 98.90% (365) | flavodoxin oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_1627 | - | 1e-117 | 61.25% (369) | oxidoreductase FAD-binding subunit |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0335|M.marinum_M ---------MFTQT-------LTQTLAKRVLGSGLVDLLTGPHGIDRYTE MUL_4786|M.ulcerans_Agy99 ---------MFTQT-------LTQTLAKRVLGSGLVDLLTGPHGIDRYTE MAV_5168|M.avium_104 ---------MFTQTVQASGRVLARTVRQRVLGSELLDLLTGPHGVDRYTE Mflv_4815|M.gilvum_PYR-GCK ---------MFTEV-----------LTKRSRRFALLDLLTGPHGVDRYTE Mvan_1627|M.vanbaalenii_PYR-1 ---------MFTET-----------LTK-VRRSALLDLLTGPHGVDRYTE MSMEG_1742|M.smegmatis_MC2_155 ---------MFTQTTAAG---FGRRLLAGSRMARLADLLTGPHGVDRYTE MAB_1588c|M.abscessus_ATCC_199 -------MTFLTKATR-------RILTPDSSLGRLLTAALTPHAVDRYLE Mb3259c|M.bovis_AF2122/97 MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPDDYLH Rv3230c|M.tuberculosis_H37Rv MSKKHTTLNASIIDTRRPTVAGADRHPGWHALRKIAARITTPLLPDDYLH TH_2872|M.thermoresistible__bu MAKSEIKYSARVVDTVRPQVAGVENRPVLHRLRRFAERITTPLLPDDYLH : * * * . MMAR_0335|M.marinum_M LVEPTWTLGEARAKLIDVRRTTPRSVTLTLAPNDTFRSAMAAGTGPMAGQ MUL_4786|M.ulcerans_Agy99 LVEPTWTLGEARAKLIDVRRTTPRSVTLTLAPNDTFRSAMAAGTGPLAGQ MAV_5168|M.avium_104 LVAPTWTLGEARAKVTDVRRTTPRSVTLTLDPNDTFLSSHTV----TAGQ Mflv_4815|M.gilvum_PYR-GCK LVDPTWTRGNARAKVVGVRRSTPRSVTLTLAPNRAFDG-------FRAGQ Mvan_1627|M.vanbaalenii_PYR-1 LVDPTWTRGQARARVVGVRRSTPRSVTLTLAPNRAFAG-------FRAGQ MSMEG_1742|M.smegmatis_MC2_155 LVEPTWSRHDARARVVAVRRQTPRSVTLTLEPNGAFTG-------FRAGQ MAB_1588c|M.abscessus_ATCC_199 LVDPMITWEEARARVIRVQRRTTRSVTLTLRTTHQFKG-------FHAGQ Mb3259c|M.bovis_AF2122/97 LANPLWSARELRGRILGVRRETEDSATLFIKPGWGFSFD------YQPGQ Rv3230c|M.tuberculosis_H37Rv LANPLWSARELRGRILGVRRETEDSATLFIKPGWGFSFD------YQPGQ TH_2872|M.thermoresistible__bu LINPLWSARELRGRVEDVRRETEDSATLVIKPGWGFSFD------YQPGQ * * : : *.:: *:* * *.** : . * .** MMAR_0335|M.marinum_M YVNLTVDIDGRRHTRCYSPAN----AEGS-ETLELTIGRHDGGLVSTYLC MUL_4786|M.ulcerans_Agy99 YVNLTVDIDGRRHTRCYSPAN----AEGS-ETLELTIGRHDGGLVSTYLY MAV_5168|M.avium_104 YVNLTVEIDGRRHTRCYSPAN----REGA-ATLELTIGRHDGGLVSNHLY Mflv_4815|M.gilvum_PYR-GCK HINVSVEIDGRRRTRPYSPAN----AEGE-ANIELTIGRHDGGLVSTYLF Mvan_1627|M.vanbaalenii_PYR-1 HVNVSVDIDGRRRTRPYSPAN----ADTD-PYLELTIGRHDGGLVSTYLF MSMEG_1742|M.smegmatis_MC2_155 HINLSVEINGRRRTRCYSPAS----AEGA-EAIELTIGRHDGGLVSTYLC MAB_1588c|M.abscessus_ATCC_199 FVQLGVVIDGVRHVRCFSPSC----ADDAREIIELTIARRPDGLVSNYLY Mb3259c|M.bovis_AF2122/97 YIGIGLLVDGCWRWRSYSLTSSPAASG-SARMVTVTVKAMPEGFLSTHLV Rv3230c|M.tuberculosis_H37Rv YIGIGLLVDGRWRWRSYSLTSSPAASG-SARMVTVTVKAMPEGFLSTHLV TH_2872|M.thermoresistible__bu YIGIGLPVDGRWRWRSYSLTSPAVTSGRGGRTITITVKAMPEGFLSTHLV .: : : ::* : * :* : : :*: *::*.:* MMAR_0335|M.marinum_M DHARRGMVVGLAGVGGDFVLPQRRPRRILFVSGGSGITPVLAMLRTLVAQ MUL_4786|M.ulcerans_Agy99 DHARRGMVVGLAGVGGDFVLPQRRPRRILFVSGGSGITPVLAMLRTLVAQ MAV_5168|M.avium_104 DHARRGMVVGLAGVGGDFVLPDPRPRRVLFVSGGSGITPVMAMVRTLVSQ Mflv_4815|M.gilvum_PYR-GCK DHARRGMVVGLDSVGGDFVLPARPAENILFVSGGSGITPVMSMLRTLRAR Mvan_1627|M.vanbaalenii_PYR-1 ERARVGMVVGLDSVAGDFTLPAIPGP-TLFVSGGSGITPVMSMLRTLRAR MSMEG_1742|M.smegmatis_MC2_155 DHAYAGMVLGLDSVGGDFVLPDTPPERILFVSGGSGITPVLSMLRTLRAQ MAB_1588c|M.abscessus_ATCC_199 KHAAVGDVYSITPAAGTFVLPAPRPIRTLLIAAGSGITPVLSMARTLVGN Mb3259c|M.bovis_AF2122/97 AGVKPGTIVRLAAPQGNFVLPDPAPPLILFLTAGSGITPVMSMLRTLVRR Rv3230c|M.tuberculosis_H37Rv AGVKPGTIVRLAAPQGNFVLPDPAPPLILFLTAGSGITPVMSMLRTLVRR TH_2872|M.thermoresistible__bu EGVKPGTIVRLAAPQGNFVMPNPAPPQVLFLTAGSGITPIMSMLRTLERR . * : : * *.:* *:::.******:::* *** . MMAR_0335|M.marinum_M HHLHIHGAEIAFIHYARNPAEACYRAELA----ALPGVRVLHGYTQSG-G MUL_4786|M.ulcerans_Agy99 HHLHIHGAEIAFIHYAHNPAEACYRAELA----ALPGVRVLHGYTQSG-G MAV_5168|M.avium_104 R----HRGEIAFIHYAPTPAEACYRDELA----ALPSVRVLHGYTRSA-G Mflv_4815|M.gilvum_PYR-GCK R----HAGQVTFVHYARSADEACYRAELAVIAREMPNVTVLHGYTRVATD Mvan_1627|M.vanbaalenii_PYR-1 R----HAGEVVFVHYARSAHEACYRDELADIASEMPNVTVLHGYTRDTTG MSMEG_1742|M.smegmatis_MC2_155 A----FTGEVGFLHYARSADEACYRDELDGIRAAIPHLRVLHGYTRDAHG MAB_1588c|M.abscessus_ATCC_199 G----YPGQLAVLYYAPTAADNAYAGELAALG-EVPSVTVRVEYTRDG-- Mb3259c|M.bovis_AF2122/97 N----QITDVVHLHSAPTAADVMFGAELAALAADHPGYRLSVRETRAQ-- Rv3230c|M.tuberculosis_H37Rv N----QITDVVHLHSAPTAADVMFGAELAALAADHPGYRLSVRETRAQ-- TH_2872|M.thermoresistible__bu D----QITDIVHIHSVPTPSDAMFSGELADLQRRHPSYRFRLRTTRTE-- :: :: . .. : : ** * . *: MMAR_0335|M.marinum_M GDLVGRFGPDHLAAAMD--APDAVFVCGPTTLVDAVRENCEN------VF MUL_4786|M.ulcerans_Agy99 GDLVGRFGPDHLAAAMD--APDAVFVCGPTTLVDAVRENCEN------VF MAV_5168|M.avium_104 GDLSGRFGPDHLAAAMP--APDAVFVCGPTSLVDAVREHCDN------VY Mflv_4815|M.gilvum_PYR-GCK SDLDGRFGAGQLPAGV--THADAVYACGPPALVDAVRELHPH------AE Mvan_1627|M.vanbaalenii_PYR-1 SDLPPRFERAGIEP-------QAVYVCGPPALVDAVREVYPD------AA MSMEG_1742|M.smegmatis_MC2_155 TDLVGRFGPDHLAAALPGNRPDAVYVCGPTDLVAAVEEHCDN------VR MAB_1588c|M.abscessus_ATCC_199 ---GQHFSAEQLQAVAPWHADAQTFLCGPPSLHEAVSALYAERGLSDRLH Mb3259c|M.bovis_AF2122/97 ----GRLDLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGASDRLH Rv3230c|M.tuberculosis_H37Rv ----GRLDLTRIGQQVPDWRERQTWACGPEGVLNQADKVWSSAGASDRLH TH_2872|M.thermoresistible__bu ----GRLDLSRLDDEVGDWRSRQTWACGPEGLLTAAERVWLGAGIGDRLH :: : .: *** : . MMAR_0335|M.marinum_M TESFVPAPIEAPAQPSGGRVRFADSG-IDVVDDGRSLLEQAESAGLAPEN MUL_4786|M.ulcerans_Agy99 TESFVPAPIEAPAQPSGGRVRFADSG-IDVVDDGRSLLEQAESAGLAPEN MAV_5168|M.avium_104 TESFTPPVLEASADPSGGRVTFSDSG-VDVVDDGRSLLEQAEAAGLSPQN Mflv_4815|M.gilvum_PYR-GCK SESFVPPVFTAD-ESGGGTVSFTTAG-VDVVDDGRPLLNQAEDAGLAPES Mvan_1627|M.vanbaalenii_PYR-1 SESFVPPVLSG--ESSGGRVTFTESG-VDVVDDGRPLLNQAEDAGLTPES MSMEG_1742|M.smegmatis_MC2_155 SECFVPPTFSA--SATGGTVTFTDSA-VSVTDDGQPLLTQAEAAGLTPLS MAB_1588c|M.abscessus_ATCC_199 TEEFTLATAGNT-GEAGGVLRFATSG-ITAENDGRPILEQAEAAGLQPEF Mb3259c|M.bovis_AF2122/97 LERFAVSKTAPA--GAGGTVTFARSGKSVAADAATSLMDAGEGAGVQLPF Rv3230c|M.tuberculosis_H37Rv LERFAVSKTAPA--GAGGTVTFARSGKSVAADAATSLMDAGEGAGVQLPF TH_2872|M.thermoresistible__bu LERFAVARVANP--GGGGTIEFARSGKSTVVDAATSLMDAGEQAGVQMPF * *. . ** : *: :. . : . .:: .* **: MMAR_0335|M.marinum_M GCRMGICHTCTRRKTSGTVRNLVTGAVSVAPDEDVQVCVSVPVGDVDLSL MUL_4786|M.ulcerans_Agy99 GCRMGICHTCTRRKTSGTVRNLVTGAVSVAPDEDVQICVSVPVGDVDLSL MAV_5168|M.avium_104 GCRMGICHTCTRRKTAGTVRNLVTGAVSTAPDEDVQICVSVPVGDVDLSL Mflv_4815|M.gilvum_PYR-GCK GCRMGICFSCTRRKTSGVVRNVVTGAVSSTEEEDVQICVSAAVGDVDIDL Mvan_1627|M.vanbaalenii_PYR-1 GCRMGICFSCTRRKTSGAVRNVITGVVSSTEEEDVQICVSAPVGDVDVAL MSMEG_1742|M.smegmatis_MC2_155 GCRMGICHSCTRTKTRGAVRNLITGAVSGTDNEDIQICVTAPVGDVDIDL MAB_1588c|M.abscessus_ATCC_199 GCRMGICFACTAVKTSGCTRNLRTGDENDDPDQHIQLCITAPVGDVSINL Mb3259c|M.bovis_AF2122/97 GCRMGICQSCVVDLVEGHVRDLRTG-QRHEPGTRVQTCVSAASGDCVLDI Rv3230c|M.tuberculosis_H37Rv GCRMGICQSCVVDLVEGHVRDLRTG-QRHEPGTRVQTCVSAASGDCVLDI TH_2872|M.thermoresistible__bu GCRMGICQSCVIGLVDGHVRDLRTG-EVHDPGTRVQTCVSAAAGDCVLDI ******* :*. . * .*:: ** :* *::.. ** : :