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M. marinum M MMAR_0107 (celA)

annotation: cellobiohydrolase a (1,4-beta-cellobiosidase a) CelA
coordinates: 133857 - 134909
length: 350

LAFVELWHYFAGVMSSAFGALARRIAPFLAVSAAAYLAFFAAPAPVVPAPPITLVDGANPLAGQPFYVDP
GSAAMVAARNATPPSPELNAIANTPQSYWLDQAFPASTVGGTVARQTGAAQAAGAMPILTLYGIPHRDCG
SYASGGFATGADYRAWIDAISSGLGSAPAAIIVEPDALAMADCLSADQRQERFDLVRYAVNTLTRDPAAA
VYVDGGHSRWVSAEEMAARLNQVDVGHARGFSLNISNFYTTDEEIGYGEAISGMTNGSHYVIDTGRNGVG
PAPESPLNWCNPDGRALGVAPTTATAGAHADAYLWIKRPGESDGSCGRGEPQAGHFVSQYAIDLAHNAGQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0107celA-100% (350)cellobiohydrolase a (1,4-beta-cellobiosidase a) CelA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0063celA11e-17282.29% (350) endo-1,4-beta-glucanase
M. gilvum PYR-GCKMflv_1003-1e-11159.23% (336) cellulase
M. tuberculosis H37RvRv0062celA11e-17282.57% (350) endo-1,4-beta-glucanase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4777c-1e-11465.99% (297) cellulase CelA
M. avium 104MAV_0326-1e-13172.19% (302) endoglucanase A
M. smegmatis MC2 155MSMEG_6752-1e-11865.84% (322) endoglucanase A
M. thermoresistible (build 8)TH_0192celA1e-11561.83% (338) POSSIBLE CELLULASE CELA1 (ENDOGLUCANASE)
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5837-1e-10756.76% (340) cellulase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1003|M.gilvum_PYR-GCK          -------------------------------------------MSSAARA
Mvan_5837|M.vanbaalenii_PYR-1       --------------------------------MFGGTAKFPQVTFSAAGV
TH_0192|M.thermoresistible__bu      ----------------------------------------VDVMSTAAHA
MSMEG_6752|M.smegmatis_MC2_155      --------------------------------------------------
MAB_4777c|M.abscessus_ATCC_199      --------------------------------------------------
Mb0063|M.bovis_AF2122/97            MTRRTGQRWRGTLPGRRPWTRPAPATCRRHLAFVELRHYFARVMSSAIGS
Rv0062|M.tuberculosis_H37Rv         MTRRTGQRWRGTLPGRRPWTRPAPATCRRHLAFVELRHYFARVMSSAIGS
MMAR_0107|M.marinum_M               ------------------------------MAFVELWHYFAGVMSSAFGA
MAV_0326|M.avium_104                --------------------------------------------------
                                                                                      

Mflv_1003|M.gilvum_PYR-GCK          AARWIAPFLTVAAVAGFAVAAQPAHRGTAPEVRLVSDANPLVGRPFYVNP
Mvan_5837|M.vanbaalenii_PYR-1       IARWITPCLAVAAIAATGVVAEPGPIPAAPVVRLASEANPLVGLPFYVNP
TH_0192|M.thermoresistible__bu      AARSILPLLTVAAVA-VGVLTGTAP-GTTPAIRLVSDANPLAGHTFYVNP
MSMEG_6752|M.smegmatis_MC2_155      --------MAVTALAGAGALAEPVRPGAAIEVRLASDGNPLAGQTFYVDP
MAB_4777c|M.abscessus_ATCC_199      -----------MAVLSLGIFLGP----------VAEADNPLDGQGFYVNP
Mb0063|M.bovis_AF2122/97            VARWIVPLLGVAAVASIGVIADPVRVVRAPALILVDAANPLAGKPFYVDP
Rv0062|M.tuberculosis_H37Rv         VARWIVPLLGVAAVASIGVIADPVRVVRAPALILVDAANPLAGKPFYVDP
MMAR_0107|M.marinum_M               LARRIAPFLAVSAAAYLAFFAAPAPVVPAPPITLVDGANPLAGQPFYVDP
MAV_0326|M.avium_104                ----------------MGPVAEP-----APAIRLAADGNPLAGAPFYVNP
                                                     .    .          :.   *** *  ***:*

Mflv_1003|M.gilvum_PYR-GCK          NSKGTRAAQSN--PDPLLAAVVNTPTAYWMDH-ISTPAVD---AKYIATA
Mvan_5837|M.vanbaalenii_PYR-1       QSKGMRAAQGN--PDPLLSAVVNTPTAYWMDH-ISTPAVD---AKYIATA
TH_0192|M.thermoresistible__bu      DSKAARAAKGD--PSPELDIIVNTPTAYWMDH-LSSPAVD---AKYIADA
MSMEG_6752|M.smegmatis_MC2_155      NSKAMRALKGN--PSPELEMIANTPHAYWMDN-VSTFAVD---AKYIQTA
MAB_4777c|M.abscessus_ATCC_199      NSAAMRAAQGA--GSPELTSIANTPQAYWMDN-VSSPSVD---AKYISAA
Mb0063|M.bovis_AF2122/97            ASAAMIAARNANPPNAELTSVANTPQSYWLDQAFPPATVGGTVARYTGAA
Rv0062|M.tuberculosis_H37Rv         ASAAMVAARNANPPNAELTSVANTPQSYWLDQAFPPATVGGTVARYTGAA
MMAR_0107|M.marinum_M               GSAAMVAARNATPPSPELNAIANTPQSYWLDQAFPASTVGGTVARQTGAA
MAV_0326|M.avium_104                NSAAMRAAQSADPPSPELTTIANTPQAYWIVPGGSAATVG----KYVGDA
                                     * .  * :.    .. *  :.*** :**:    .. :*.    :    *

Mflv_1003|M.gilvum_PYR-GCK          QAAGTTPVLALYGIPNRDCGSYAAGGFGSAGSYRAWIDGVAGAIGGGPAA
Mvan_5837|M.vanbaalenii_PYR-1       QAAGTMPVLALYGIPNRDCGSYAAGGFGSAGAYRAWIDGVAAAIGPGRAA
TH_0192|M.thermoresistible__bu      QAAGEMPILALYGIPHRDCGSYAAGGFGSAAAYRGWIDGVAAAIGSGPAA
MSMEG_6752|M.smegmatis_MC2_155      QAAGTMPILALYGIPNRDCGSLAAGGFGSAAAYRGWIDGVAGAIGSGPAA
MAB_4777c|M.abscessus_ATCC_199      QASGATPVLALYAIPHRDCGSFAAGGFGSADAYKGWIDGVAAAIGAGPAV
Mb0063|M.bovis_AF2122/97            QAAGAMPVLTLYGIPHRDCGSYASGGFATGTDYRGWIDAVASGLGSSPAT
Rv0062|M.tuberculosis_H37Rv         QAAGAMPVLTLYGIPHRDCGSYASGGFATGTDYRGWIDAVASGLGSSPAT
MMAR_0107|M.marinum_M               QAAGAMPILTLYGIPHRDCGSYASGGFATGADYRAWIDAISSGLGSAPAA
MAV_0326|M.avium_104                NAAGAIPVLAIYGIPHRDCGSFAAGGMASADDYRGWIDGIASGVGASRVA
                                    :*:*  *:*::*.**:***** *:**:.:.  *:.***.::..:* . ..

Mflv_1003|M.gilvum_PYR-GCK          VILEPDALAMIDCLSPGRQQERLELIGYAVDTLTRNPATAVYVDAGHSRW
Mvan_5837|M.vanbaalenii_PYR-1       VILEPDALAMIDCLSPGQQQERLELIGYAVDTLSRNPGTAVYVDAGHPRW
TH_0192|M.thermoresistible__bu      VILEPDALAMSGCLSSEQRQERFELIRYAVDTLTRNPATAVYIDAGHPRW
MSMEG_6752|M.smegmatis_MC2_155      VILEPDALAMADCLSPDQRQERFDLIRYAVDTLTRNPATAVYVDAGHSRW
MAB_4777c|M.abscessus_ATCC_199      VILEPDALAMADCLSGAQRQERFDLMRYAVDTLTRNPATALYIDGGHSRW
Mb0063|M.bovis_AF2122/97            IIVEPDALAMADCLSPDQRQERFDLVRYAVDTLTRDPAAAVYVDAGHSRW
Rv0062|M.tuberculosis_H37Rv         IIVEPDALAMADCLSPDQRQERFDLVRYAVDTLTRDPAAAVYVDAGHSRW
MMAR_0107|M.marinum_M               IIVEPDALAMADCLSADQRQERFDLVRYAVNTLTRDPAAAVYVDGGHSRW
MAV_0326|M.avium_104                IVVEPDALAMADCLSGDQRQERFDLVRYAVDTLTRDPNAAVYVDAGHLRW
                                    :::******* .***  ::***::*: ***:**:*:* :*:*:*.** **

Mflv_1003|M.gilvum_PYR-GCK          VPADVMAGRLNQVGIAKARGFSLNTANFFTTEESVGYGGAISGMTGGKPF
Mvan_5837|M.vanbaalenii_PYR-1       VAADVMAGRLNQVGIDRARGFSLNTANFFTTEESMGYGGAISGMTGGKPF
TH_0192|M.thermoresistible__bu      VSVEDMAGMLNEVGVARARGFSLNTANFFTTEESIGYGEAISGLTGGAHY
MSMEG_6752|M.smegmatis_MC2_155      VNAEDMAARLNEVGVTKTRGFSLNTANFFTTEEEIGYGEAISGLTNGSHY
MAB_4777c|M.abscessus_ATCC_199      VSADVMAARLNEVGVSKARGFSLNTANFFTTDEEIGYGDAISGMTNGAHY
Mb0063|M.bovis_AF2122/97            LSAEAMAARLNDVGVGRARGFSLNVSNFYTTDEEIGYGEAISGLTNGSHY
Rv0062|M.tuberculosis_H37Rv         LSAEAMAARLNDVGVGRARGFSLNVSNFYTTDEEIGYGEAISGLTNGSHY
MMAR_0107|M.marinum_M               VSAEEMAARLNQVDVGHARGFSLNISNFYTTDEEIGYGEAISGMTNGSHY
MAV_0326|M.avium_104                HSPEDMAARLNQAGVAHARGFSVNTANFYTTEDEIGYGEAISGLTNGAHY
                                       : **. **:..: ::****:* :**:**::.:*** ****:*.*  :

Mflv_1003|M.gilvum_PYR-GCK          VIDTSRNGAGPVEGDDLYWCNPSGRALGVRPTTDTGNPMVDAFLWVKRPG
Mvan_5837|M.vanbaalenii_PYR-1       VIDTSRNGAGPVEGDDLYWCNPSGRALGARPTTNTGNPMVDAFLWVKRPG
TH_0192|M.thermoresistible__bu      VIDTSRNGAGPLDSD--AWCNPPGRALGAFPTTATAGAHADAYLWIKRPG
MSMEG_6752|M.smegmatis_MC2_155      VIDTSRNGVGPVDSD--SWCNPPGRALGSPPTTATAGAHADAYLWVKRPG
MAB_4777c|M.abscessus_ATCC_199      VIDTSRNGAGP-TSDALYWCNPSGRALGTPPTTATASPNADAYLWVKRPG
Mb0063|M.bovis_AF2122/97            VIDTSRNGAGPAPDAPLNWCNPSGRALGAPPTTATAGAHADAYLWIKRPG
Rv0062|M.tuberculosis_H37Rv         VIDTSRNGAGPAPDAPLNWCNPSGRALGAPPTTATAGAHADAYLWIKRPG
MMAR_0107|M.marinum_M               VIDTGRNGVGPAPESPLNWCNPDGRALGVAPTTATAGAHADAYLWIKRPG
MAV_0326|M.avium_104                VIDTSRNGAGPAPDSDLNWCNPSGRALGTPPTAATAGAHADAYLWIKRPG
                                    ****.***.**       **** *****  **: *... .**:**:****

Mflv_1003|M.gilvum_PYR-GCK          ESDGACR-GAPSAGTFVAQYAIDLARNAGW
Mvan_5837|M.vanbaalenii_PYR-1       ESDGACR-GFPSAGTFMSQNAIDLARNAGW
TH_0192|M.thermoresistible__bu      ESDGACN-GHPPAGTFVARYAVELVRNAGL
MSMEG_6752|M.smegmatis_MC2_155      ESDGACN-GHPSAGTFVSQYAIDLARNAGR
MAB_4777c|M.abscessus_ATCC_199      ESDGSCDRGDPRAGTFVNQFAIDLARNAGR
Mb0063|M.bovis_AF2122/97            ESDGTCGRGEPQAGRFVSQYAIDLAHNAGQ
Rv0062|M.tuberculosis_H37Rv         ESDGTCGRGEPQAGRFVSQYAIDLAHNAGQ
MMAR_0107|M.marinum_M               ESDGSCGRGEPQAGHFVSQYAIDLAHNAGQ
MAV_0326|M.avium_104                ESDGSCGKGDPPAGNFVNQYAIDLVHNVGH
                                    ****:*  * * ** *: : *::*.:*.*