For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. leprae Br4923 MLBr_02708 (gidB)

annotation: 16S rRNA methyltransferase GidB
coordinates: 3264032 - 3264778
length: 248

FHVKHVGSYEELASFTSVKGNLGFDTVFEAVFMIFGPRLNIAQRYVDLLANTGIERGLLGPHEANRLWDR
HLLNSAVVAELLDPGDRVVDIGSGAGLPGLPLAIARPDLQVVLLEPLLRRVTFLREVVAELGLDVEVVRG
RAEELWVRDRIGERDVAVSRAVAALDKLTKWSIPLLRPGGQILAIKGEHVFDEIHQHRRVMASLGAVDVM
VVVCGANYLCRPVTVVLTRCGQQMRHKPARVGDRKTQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02708gidB-100% (248)16S rRNA methyltransferase GidB

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3950cgidB2e-8167.74% (217) 16S rRNA methyltransferase GidB
M. gilvum PYR-GCKMflv_0833gidB1e-6758.79% (199) methyltransferase GidB
M. tuberculosis H37RvRv3919cgidB2e-8067.28% (217) 16S rRNA methyltransferase GidB
M. abscessus ATCC 19977MAB_4951cgidB8e-6355.20% (221) methyltransferase GidB (glucose-inhibited division protein
M. marinum MMMAR_5483gidB2e-8070.18% (218) glucose-inhibited division protein B Gid
M. avium 104MAV_5308gidB1e-7862.04% (245) glucose-inhibited division protein B
M. smegmatis MC2 155MSMEG_6940gidB9e-7361.93% (218) methyltransferase GidB
M. thermoresistible (build 8)TH_0763gid8e-7060.09% (218) PROBABLE GLUCOSE-INHIBITED DIVISION PROTEIN B GID
M. ulcerans Agy99MUL_5072gid2e-5972.15% (158) glucose-inhibited division protein B Gid
M. vanbaalenii PYR-1Mvan_6073gidB2e-6963.32% (199) methyltransferase GidB

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0833|M.gilvum_PYR-GCK          -MKHAEIPPPPDAAA------------------EVFGPALGAARRYAEIL
Mvan_6073|M.vanbaalenii_PYR-1       -MKHAEVPPPPEAAE------------------AVFGPALEKAHLYARIL
MSMEG_6940|M.smegmatis_MC2_155      -MKHGSVPATPEAAS------------------LVFGDRLEAAELYARIL
TH_0763|M.thermoresistible__bu      -VKHGAVAAPPPAAA------------------TIFGPALDRAQRYAAIL
MMAR_5483|M.marinum_M               -----MTQPLDDAAS------------------AIFGPRLELAQRYADWL
MUL_5072|M.ulcerans_Agy99           -----MTQPLDDAAS------------------AIFGPRLELAQCYADWL
Mb3950c|M.bovis_AF2122/97           ------MSPIEPAAS------------------AIFGPRLGLARRYAEAL
Rv3919c|M.tuberculosis_H37Rv        ------MSPIEPAAS------------------AIFGPRLGLARRYAEAL
MAV_5308|M.avium_104                ---MKHVGPVEPAAGGPEVPPVAALGAAPESAAALFGPRLATAQRYAEVL
MLBr_02708|M.leprae_Br4923          MFHVKHVGSYEELASFTSVKGNLGFDTVFEAVFMIFGPRLNIAQRYVDLL
MAB_4951c|M.abscessus_ATCC_199      -MKHGETLPVPEAAA------------------EVFGERLARAVEYVAAL
                                            .    *                    :**  *  *  *.  *

Mflv_0833|M.gilvum_PYR-GCK          AGAGVERGLLGPREVDRIWDRHILNCAVIGELVEAGERVADVGSGAGLPG
Mvan_6073|M.vanbaalenii_PYR-1       AGAGVERGLLGPREVERLWDRHILNCAVVGELLQPGERVADIGSGAGLPG
MSMEG_6940|M.smegmatis_MC2_155      AGAGVEWGLLGPREVDRVWERHILNSAALGELMEPGERVADIGSGAGLPG
TH_0763|M.thermoresistible__bu      AGAGVERGLLGPREVDRIWDRHVLNSAVTSELIEPGERVADIGSGAGLPG
MMAR_5483|M.marinum_M               ATAGVERGLLGPREVDRLWERHVLNSAVIGELLDQGERVVDIGSGAGLPG
MUL_5072|M.ulcerans_Agy99           GTAGVERGLLGPREVDRLWERHVLNSAVIGELLDHGERVVDIGSGAGLPA
Mb3950c|M.bovis_AF2122/97           AGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPG
Rv3919c|M.tuberculosis_H37Rv        AGPGVERGLVGPREVGRLWDRHLLNCAVIGELLERGDRVVDIGSGAGLPG
MAV_5308|M.avium_104                GTAGVERGLLGPREVDRIWDRHILNSAAVAGLLGRGDRIIDIGSGAGLPG
MLBr_02708|M.leprae_Br4923          ANTGIERGLLGPHEANRLWDRHLLNSAVVAELLDPGDRVVDIGSGAGLPG
MAB_4951c|M.abscessus_ATCC_199      ATIGVERGLIGPRETGRLWGRHILNSAVLGELLEAGERVIDVGSGAGLPG
                                    .  *:* **:**:*. *:* **:**.*. . *:  *:*: *:*******.

Mflv_0833|M.gilvum_PYR-GCK          IPLALARPDVHVVLIEPLLRRSDFLREAIEDVGIE-CSVVRGRAEDRSVR
Mvan_6073|M.vanbaalenii_PYR-1       IPLALARPDVHVILIEPLLRRSEFLRETIEEIGID-CDVVRGRAEDRSVR
MSMEG_6940|M.smegmatis_MC2_155      IPLALARPDIHVTLIEPLLRRSEFLRETVTELGLD-VTVVRGRAEDREVR
TH_0763|M.thermoresistible__bu      IPLALARPDLSITLVEPMLRRSEFLHEVVAELDLE-VRVVRGRAEDPAVR
MMAR_5483|M.marinum_M               LPLAIARPDLQVVLLEPMLRRVEFLQEVVTDLGLA-VEVVRGRAEERSVR
MUL_5072|M.ulcerans_Agy99           LPLAIARHDLQVVLLEPMLRRVEFLQEVVTDLGLA-VEVVRGRAEERSVR
Mb3950c|M.bovis_AF2122/97           VPLAIARPDLQVVLLEPLLRRTEFLREMVTDLGVA-VEIVRGRAEESWVQ
Rv3919c|M.tuberculosis_H37Rv        VPLAIARPDLQVVLLEPLLRRTESLREMVTDLGVA-VEIVRGRAEESWVQ
MAV_5308|M.avium_104                IPLAIARPDLEVVLLEPLLRRSEFLTEVVDELGLA-VEVVRGRAEERPVR
MLBr_02708|M.leprae_Br4923          LPLAIARPDLQVVLLEPLLRRVTFLREVVAELGLD-VEVVRGRAEELWVR
MAB_4951c|M.abscessus_ATCC_199      IPLGIARPDVGIVLVEPMLRRTEFLREMIEQLGLTNVSVVRGRAEEPAVI
                                    :**.:** *: : *:**:***   * * : ::.:    :******:  * 

Mflv_0833|M.gilvum_PYR-GCK          EEVGPTDVVVSRAVASLDKLAKWSSPLLRPGGRMLAIKGERAAEEIEEHR
Mvan_6073|M.vanbaalenii_PYR-1       EEVGTTDVVVSRAVASLDKLTKWSSPLLRVGGRMLAIKGERADDEVQQHR
MSMEG_6940|M.smegmatis_MC2_155      DRVGEMDVVTSRAVASLDKLTRWSVPFLRDGGRMLPIKGERAEVEIEEHR
TH_0763|M.thermoresistible__bu      REVGEMDAVTSRAVAPLDKLARWSLPLLKPGGHMLAIKGARAEAEVDEHR
MMAR_5483|M.marinum_M               ERLGGSDAAVSRAVAALDKLTKWSMPLLKREGRMLAIKGERAPDEVREHR
MUL_5072|M.ulcerans_Agy99           ERLGGSDAAVSRAVAALDKLAKWSMPLLKREGRMLAIK------------
Mb3950c|M.bovis_AF2122/97           DQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRMLAIKGERAHDEVREHR
Rv3919c|M.tuberculosis_H37Rv        DQLGGSDAAVSRAVAALDKLTKWSMPLIRPNGRMLAIKGERAHDEVREHR
MAV_5308|M.avium_104                NRFGDRDAAVSRAVAALDKLTKWSMPLLRHDGRMLAIKGERAAEEVDRYR
MLBr_02708|M.leprae_Br4923          DRIGERDVAVSRAVAALDKLTKWSIPLLRPGGQILAIKGEHVFDEIHQHR
MAB_4951c|M.abscessus_ATCC_199      AEVGGADAVTSRAVAALDKIARWSLPLTRIGGRMLAIKGDRAEDEVEQYG
                                     ..*  *...*****.***:::** *: :  *::*.**            

Mflv_0833|M.gilvum_PYR-GCK          RALAALGVSELKVERCGARFVDPPATVVVGFQATAPEK----RPRSGRRQ
Mvan_6073|M.vanbaalenii_PYR-1       RAMAALGVSEVKVERCGGQYVEPPATVVVGFQGVAKVS----QSRSGRRH
MSMEG_6940|M.smegmatis_MC2_155      RVMESLGAVDARVVRCGANYLSPPVTVVDARRRAAKPG----RNKSGRTA
TH_0763|M.thermoresistible__bu      RVLNRLKAVDVRVVRCGADLLDPPATVVVARRAAAKQGGYP-PTRSGRRR
MMAR_5483|M.marinum_M               RVMESLGAADVRVVPCGANYLQPPATVVVARRGDTRGPNRR-VSPRRTGG
MUL_5072|M.ulcerans_Agy99           -----------------------------------RGASSR---------
Mb3950c|M.bovis_AF2122/97           RVMIASGAVDVRVVTCGANYLRPPATVVFARRG--KQIARG-SARMASGG
Rv3919c|M.tuberculosis_H37Rv        RVMIASGAVDVRVVTCGANYLRPPATVVFARRG--KQIARG-SARMASGG
MAV_5308|M.avium_104                RVMTASGAADVRVVTCGANYLRPPATVVSARRA--KPPHPK-SARTGKAG
MLBr_02708|M.leprae_Br4923          RVMASLGAVDVMVVVCGANYLCRPVTVVLTRCG--QQMRHK-PARVGDRK
MAB_4951c|M.abscessus_ATCC_199      SALGQLGADDVRVVQCGTRYLDSPTTVVVARRKECDGNRQRGSSRGGSRK
                                                                                      

Mflv_0833|M.gilvum_PYR-GCK          R--------
Mvan_6073|M.vanbaalenii_PYR-1       R--------
MSMEG_6940|M.smegmatis_MC2_155      RSRGRTGRR
TH_0763|M.thermoresistible__bu      G--------
MMAR_5483|M.marinum_M               APA------
MUL_5072|M.ulcerans_Agy99           ---------
Mb3950c|M.bovis_AF2122/97           TA-------
Rv3919c|M.tuberculosis_H37Rv        TA-------
MAV_5308|M.avium_104                TR-------
MLBr_02708|M.leprae_Br4923          TQ-------
MAB_4951c|M.abscessus_ATCC_199      RSR------