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M. leprae Br4923 MLBr_02647 (-)

annotation: methionine sulfoxide reductase A
coordinates: 3166734 - 3167267
length: 177

MARTNTRKAILAGGCFWGIQNLFRRQPGVISTRVGYTGGGTPNATYRNHGMHAEAVEIIYDPAITDYRTL
LEFFFQIHDPTTRNRQGNDQGTSYRSAIFYLDDEQKKVALDTIAAVEASSLWPGKVVTEVSLAEDFWEAE
PEHQDYLQHYPNGYTCHFVRPNWKLPRRAPADAKADS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02647--100% (177)methionine sulfoxide reductase A

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0142cmsrA1e-8380.00% (170) methionine sulfoxide reductase A
M. gilvum PYR-GCKMflv_1105-6e-7776.69% (163) methionine sulfoxide reductase A
M. tuberculosis H37RvRv0137cmsrA1e-8380.00% (170) methionine sulfoxide reductase A
M. abscessus ATCC 19977MAB_0120-1e-2741.25% (160) peptide methionine sulfoxide reductase
M. marinum MMMAR_0347msrA4e-8382.74% (168) peptide methionine sulfoxide reductase MsrA
M. avium 104MAV_5159msrA3e-8583.73% (166) methionine sulfoxide reductase A
M. smegmatis MC2 155MSMEG_6477msrA7e-7877.84% (167) methionine sulfoxide reductase A
M. thermoresistible (build 8)TH_0081-3e-7576.69% (163) PROBABLE PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA
M. ulcerans Agy99MUL_4773msrA2e-8282.14% (168) methionine sulfoxide reductase A
M. vanbaalenii PYR-1Mvan_5709-7e-7776.07% (163) methionine sulfoxide reductase A

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1105|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5709|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_6477|M.smegmatis_MC2_155      --------------------------------------------------
TH_0081|M.thermoresistible__bu      --------------------------------------------------
Mb0142c|M.bovis_AF2122/97           --------------------------------------------------
Rv0137c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0347|M.marinum_M               --------------------------------------------------
MUL_4773|M.ulcerans_Agy99           --------------------------------------------------
MAV_5159|M.avium_104                --------------------------------------------------
MLBr_02647|M.leprae_Br4923          --------------------------------------------------
MAB_0120|M.abscessus_ATCC_1997      MASWVDNVRDQILGRIEDGLKPGKSAIVAEDAALPGRATPIRVSGTHFVN
                                                                                      

Mflv_1105|M.gilvum_PYR-GCK          --------MSDHKRAVLAGGCFWGMQDLIRKQPGVVSTRVGYTGGQNDHP
Mvan_5709|M.vanbaalenii_PYR-1       --------MSDHKRAVLAGGCFWGMQDLIRKQPGVVSTRVGYTGGQNDHP
MSMEG_6477|M.smegmatis_MC2_155      --------MGNHATAILAGGCFWGMQDLIRKQPGVVSTRVGYTGGQNDHP
TH_0081|M.thermoresistible__bu      --------VSEYKKAILAGGCFWGMQELIRKQPGVVSTRVGYTGGENDHP
Mb0142c|M.bovis_AF2122/97           --------MTSNQKAILAGGCFWGLQDLIRNQPGVVSTRVGYSGGNIPNA
Rv0137c|M.tuberculosis_H37Rv        --------MTSNQKAILAGGCFWGLQDLIRNQPGVVSTRVGYSGGNIPNA
MMAR_0347|M.marinum_M               --------MTSPQKAILAGGCFWGMQDLIRKQPGVIATRVGYSGGDVANA
MUL_4773|M.ulcerans_Agy99           --------MTSPQKAILAGGCFWGMQDLIRKQPGVIATRVGYSGGDVANA
MAV_5159|M.avium_104                --------MTNTQKAILAGGCFWGMQELIRKQPGVVSTRVGYTGGDVPNA
MLBr_02647|M.leprae_Br4923          ------MARTNTRKAILAGGCFWGIQNLFRRQPGVISTRVGYTGGGTPNA
MAB_0120|M.abscessus_ATCC_1997      GHTTVPPFPDGCELAVFGEGCFWGAERGFWKLPGVYSTAVGYAGGYTPNP
                                                  *::. ***** :  : . *** :* ***:**   :.

Mflv_1105|M.gilvum_PYR-GCK          TYRN----HPGHAEAIEIVYDPAQTDYRALLEFFFQIHDPTTKNRQGNDI
Mvan_5709|M.vanbaalenii_PYR-1       TYRN----HPGHAEAIEIVYDPAQTDYRALLEFFFQIHDPTTKNRQGNDV
MSMEG_6477|M.smegmatis_MC2_155      TYRN----HPGHAEAVEIVYDPAQTDYRALLEFFFQIHDPTTKDRQGNDV
TH_0081|M.thermoresistible__bu      TYRN----HPGHAEAIEIVYDPAQTDYRTLLEFFFQIHDPTTKDRQGNDI
Mb0142c|M.bovis_AF2122/97           TYRN----HGTHAEAVEIIFDPTVTDYRTLLEFFFQIHDPTTKDRQGNDR
Rv0137c|M.tuberculosis_H37Rv        TYRN----HGTHAEAVEIIFDPTVTDYRTLLEFFFQIHDPTTKDRQGNDR
MMAR_0347|M.marinum_M               TYRN----HGTHAEAVEIIFDPQATDYRTLLEFFFQIHDPTTPNRQGNDR
MUL_4773|M.ulcerans_Agy99           TYRN----HGTHAEAVEIIFDPQATDYRTLLEFFFQIHDPTTPNRQGNDR
MAV_5159|M.avium_104                TYRN----HGTHAEAVEIIYDPAVTDYRQILEFFFQIHDPTTKDRQGNDR
MLBr_02647|M.leprae_Br4923          TYRN----HGMHAEAVEIIYDPAITDYRTLLEFFFQIHDPTTRNRQGNDQ
MAB_0120|M.abscessus_ATCC_1997      TYEEVCSGRTGHAEVVLVVFDPREVTYGQLLVQFWESHDPTQGMRQGNDR
                                    **.:    :  ***.: :::**  . *  :*  *:: ****   ***** 

Mflv_1105|M.gilvum_PYR-GCK          GTSYRSEIFYVDEEQRQIALDTIADVDASGLWP--GKVVTEVSPAP----
Mvan_5709|M.vanbaalenii_PYR-1       GTSYRSEIFYVDDEQRRIALDTIADVDASGLWP--GKVVTDVSPAP----
MSMEG_6477|M.smegmatis_MC2_155      GSSYRSAIFYLDEEQKRIALETIADVDASGLWP--GKVVTEVTPAS----
TH_0081|M.thermoresistible__bu      GSSYRSAIFYLDEEQKRIAEDTIADVDASGLWP--GKVVTEVTPAG----
Mb0142c|M.bovis_AF2122/97           GTSYRSAIFYFDEQQKRIALDTIADVEASGLWP--GKVVTEVSPAG----
Rv0137c|M.tuberculosis_H37Rv        GTSYRSAIFYFDEQQKRIALDTIADVEASGLWP--GKVVTEVSPAG----
MMAR_0347|M.marinum_M               GTSYRSAIYYLDDEQKRVALDTIADVEASGLWP--GKVVTEVSPAG----
MUL_4773|M.ulcerans_Agy99           GTSYRSAIYYLDDEQKRVALDTIADVEASGLWP--GKVVTEVSPAG----
MAV_5159|M.avium_104                GPSYRSAIFYTDDEQKRIALDTIADVEASGLWP--GKVVTEVSPAG----
MLBr_02647|M.leprae_Br4923          GTSYRSAIFYLDDEQKKVALDTIAAVEASSLWP--GKVVTEVSLAE----
MAB_0120|M.abscessus_ATCC_1997      GTQYRSVIYTTSEGQAVQAAESAARYEAALADAGYGAITTEIAPLNGPVG
                                    *..*** *:  .: *   * :: *  :*:   .  * :.*:::       

Mflv_1105|M.gilvum_PYR-GCK          ----DFWEAEPEHQDYLERYPTGY-----TCHFPRPGWKLPKRAEV----
Mvan_5709|M.vanbaalenii_PYR-1       ----EFWEAEPEHQDYLERYPSGY-----TCHFPRPGWKLPKRAEV----
MSMEG_6477|M.smegmatis_MC2_155      ----DFWEAEPEHQDYLVHYPNGY-----TCHFPRPGWKLPRRETASQ--
TH_0081|M.thermoresistible__bu      ----TFWEAEPEHQDYLQRFPNGY-----TCHYPRPNWKLTVRSGIRGR-
Mb0142c|M.bovis_AF2122/97           ----DFWEAEPEHQDYLQRYPNGY-----TCHFVRPGWRLPRRTAESALR
Rv0137c|M.tuberculosis_H37Rv        ----DFWEAEPEHQDYLQRYPNGY-----TCHFVRPGWRLPRRTAESALR
MMAR_0347|M.marinum_M               ----DFWEAEPEHQDYLQRYPSGY-----TCHFIRPGWKLPRRATAGQ--
MUL_4773|M.ulcerans_Agy99           ----DFWEAEPEHQHYLQRYPSGY-----TCHFIRPGWKLPRRATAGQ--
MAV_5159|M.avium_104                ----DFWEAEPEHQDYLQRYPNGY-----TCHYIRPGWKLPRRATSGS--
MLBr_02647|M.leprae_Br4923          ----DFWEAEPEHQDYLQHYPNGY-----TCHFVRPNWKLPRRAPADAKA
MAB_0120|M.abscessus_ATCC_1997      HASRTFFYAEEYHQQYLAKNPNGYCGLGGTSVSCPIGLDVPPGGPAEA--
                                         *: **  **.** : *.**     *.     .  :.         

Mflv_1105|M.gilvum_PYR-GCK          ---------
Mvan_5709|M.vanbaalenii_PYR-1       ---------
MSMEG_6477|M.smegmatis_MC2_155      ---------
TH_0081|M.thermoresistible__bu      ---------
Mb0142c|M.bovis_AF2122/97           ASLSPELGT
Rv0137c|M.tuberculosis_H37Rv        ASLSPELGT
MMAR_0347|M.marinum_M               ---------
MUL_4773|M.ulcerans_Agy99           ---------
MAV_5159|M.avium_104                ---------
MLBr_02647|M.leprae_Br4923          DS-------
MAB_0120|M.abscessus_ATCC_1997      ---------