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MASWVDNVRDQILGRIEDGLKPGKSAIVAEDAALPGRATPIRVSGTHFVNGHTTVPPFPDGCELAVFGEG CFWGAERGFWKLPGVYSTAVGYAGGYTPNPTYEEVCSGRTGHAEVVLVVFDPREVTYGQLLVQFWESHDP TQGMRQGNDRGTQYRSVIYTTSEGQAVQAAESAARYEAALADAGYGAITTEIAPLNGPVGHASRTFFYAE EYHQQYLAKNPNGYCGLGGTSVSCPIGLDVPPGGPAEA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0120 | - | - | 100% (248) | peptide methionine sulfoxide reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0142c | msrA | 2e-27 | 42.50% (160) | methionine sulfoxide reductase A |
| M. gilvum PYR-GCK | Mflv_1105 | - | 5e-27 | 41.25% (160) | methionine sulfoxide reductase A |
| M. tuberculosis H37Rv | Rv0137c | msrA | 2e-27 | 42.50% (160) | methionine sulfoxide reductase A |
| M. leprae Br4923 | MLBr_02647 | - | 9e-28 | 41.25% (160) | methionine sulfoxide reductase A |
| M. marinum M | MMAR_0347 | msrA | 7e-27 | 41.25% (160) | peptide methionine sulfoxide reductase MsrA |
| M. avium 104 | MAV_5159 | msrA | 5e-28 | 41.88% (160) | methionine sulfoxide reductase A |
| M. smegmatis MC2 155 | MSMEG_6477 | msrA | 3e-27 | 41.88% (160) | methionine sulfoxide reductase A |
| M. thermoresistible (build 8) | TH_0081 | - | 9e-28 | 41.25% (160) | PROBABLE PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA |
| M. ulcerans Agy99 | MUL_4773 | msrA | 5e-27 | 41.25% (160) | methionine sulfoxide reductase A |
| M. vanbaalenii PYR-1 | Mvan_5709 | - | 3e-26 | 40.00% (160) | methionine sulfoxide reductase A |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0142c|M.bovis_AF2122/97 --------------------------------------------------
Rv0137c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0347|M.marinum_M --------------------------------------------------
MUL_4773|M.ulcerans_Agy99 --------------------------------------------------
MAV_5159|M.avium_104 --------------------------------------------------
MLBr_02647|M.leprae_Br4923 --------------------------------------------------
Mflv_1105|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5709|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6477|M.smegmatis_MC2_155 --------------------------------------------------
TH_0081|M.thermoresistible__bu --------------------------------------------------
MAB_0120|M.abscessus_ATCC_1997 MASWVDNVRDQILGRIEDGLKPGKSAIVAEDAALPGRATPIRVSGTHFVN
Mb0142c|M.bovis_AF2122/97 --------MTSNQKAILAGGCFWGLQDLIRNQPGVVSTRVGYSGGNIPNA
Rv0137c|M.tuberculosis_H37Rv --------MTSNQKAILAGGCFWGLQDLIRNQPGVVSTRVGYSGGNIPNA
MMAR_0347|M.marinum_M --------MTSPQKAILAGGCFWGMQDLIRKQPGVIATRVGYSGGDVANA
MUL_4773|M.ulcerans_Agy99 --------MTSPQKAILAGGCFWGMQDLIRKQPGVIATRVGYSGGDVANA
MAV_5159|M.avium_104 --------MTNTQKAILAGGCFWGMQELIRKQPGVVSTRVGYTGGDVPNA
MLBr_02647|M.leprae_Br4923 ------MARTNTRKAILAGGCFWGIQNLFRRQPGVISTRVGYTGGGTPNA
Mflv_1105|M.gilvum_PYR-GCK --------MSDHKRAVLAGGCFWGMQDLIRKQPGVVSTRVGYTGGQNDHP
Mvan_5709|M.vanbaalenii_PYR-1 --------MSDHKRAVLAGGCFWGMQDLIRKQPGVVSTRVGYTGGQNDHP
MSMEG_6477|M.smegmatis_MC2_155 --------MGNHATAILAGGCFWGMQDLIRKQPGVVSTRVGYTGGQNDHP
TH_0081|M.thermoresistible__bu --------VSEYKKAILAGGCFWGMQELIRKQPGVVSTRVGYTGGENDHP
MAB_0120|M.abscessus_ATCC_1997 GHTTVPPFPDGCELAVFGEGCFWGAERGFWKLPGVYSTAVGYAGGYTPNP
*::. ***** : : . *** :* ***:** :.
Mb0142c|M.bovis_AF2122/97 TYRN----HGTHAEAVEIIFDPTVTDYRTLLEFFFQIHDPTTKDRQGNDR
Rv0137c|M.tuberculosis_H37Rv TYRN----HGTHAEAVEIIFDPTVTDYRTLLEFFFQIHDPTTKDRQGNDR
MMAR_0347|M.marinum_M TYRN----HGTHAEAVEIIFDPQATDYRTLLEFFFQIHDPTTPNRQGNDR
MUL_4773|M.ulcerans_Agy99 TYRN----HGTHAEAVEIIFDPQATDYRTLLEFFFQIHDPTTPNRQGNDR
MAV_5159|M.avium_104 TYRN----HGTHAEAVEIIYDPAVTDYRQILEFFFQIHDPTTKDRQGNDR
MLBr_02647|M.leprae_Br4923 TYRN----HGMHAEAVEIIYDPAITDYRTLLEFFFQIHDPTTRNRQGNDQ
Mflv_1105|M.gilvum_PYR-GCK TYRN----HPGHAEAIEIVYDPAQTDYRALLEFFFQIHDPTTKNRQGNDI
Mvan_5709|M.vanbaalenii_PYR-1 TYRN----HPGHAEAIEIVYDPAQTDYRALLEFFFQIHDPTTKNRQGNDV
MSMEG_6477|M.smegmatis_MC2_155 TYRN----HPGHAEAVEIVYDPAQTDYRALLEFFFQIHDPTTKDRQGNDV
TH_0081|M.thermoresistible__bu TYRN----HPGHAEAIEIVYDPAQTDYRTLLEFFFQIHDPTTKDRQGNDI
MAB_0120|M.abscessus_ATCC_1997 TYEEVCSGRTGHAEVVLVVFDPREVTYGQLLVQFWESHDPTQGMRQGNDR
**.: : ***.: :::** . * :* *:: **** *****
Mb0142c|M.bovis_AF2122/97 GTSYRSAIFYFDEQQKRIALDTIADVEASGLWP--GKVVTEVSPAG----
Rv0137c|M.tuberculosis_H37Rv GTSYRSAIFYFDEQQKRIALDTIADVEASGLWP--GKVVTEVSPAG----
MMAR_0347|M.marinum_M GTSYRSAIYYLDDEQKRVALDTIADVEASGLWP--GKVVTEVSPAG----
MUL_4773|M.ulcerans_Agy99 GTSYRSAIYYLDDEQKRVALDTIADVEASGLWP--GKVVTEVSPAG----
MAV_5159|M.avium_104 GPSYRSAIFYTDDEQKRIALDTIADVEASGLWP--GKVVTEVSPAG----
MLBr_02647|M.leprae_Br4923 GTSYRSAIFYLDDEQKKVALDTIAAVEASSLWP--GKVVTEVSLAE----
Mflv_1105|M.gilvum_PYR-GCK GTSYRSEIFYVDEEQRQIALDTIADVDASGLWP--GKVVTEVSPAP----
Mvan_5709|M.vanbaalenii_PYR-1 GTSYRSEIFYVDDEQRRIALDTIADVDASGLWP--GKVVTDVSPAP----
MSMEG_6477|M.smegmatis_MC2_155 GSSYRSAIFYLDEEQKRIALETIADVDASGLWP--GKVVTEVTPAS----
TH_0081|M.thermoresistible__bu GSSYRSAIFYLDEEQKRIAEDTIADVDASGLWP--GKVVTEVTPAG----
MAB_0120|M.abscessus_ATCC_1997 GTQYRSVIYTTSEGQAVQAAESAARYEAALADAGYGAITTEIAPLNGPVG
*..*** *: .: * * :: * :*: . * :.*:::
Mb0142c|M.bovis_AF2122/97 ----DFWEAEPEHQDYLQRYPNGY-----TCHFVRPGWRLPRRTAESALR
Rv0137c|M.tuberculosis_H37Rv ----DFWEAEPEHQDYLQRYPNGY-----TCHFVRPGWRLPRRTAESALR
MMAR_0347|M.marinum_M ----DFWEAEPEHQDYLQRYPSGY-----TCHFIRPGWKLPRRATAGQ--
MUL_4773|M.ulcerans_Agy99 ----DFWEAEPEHQHYLQRYPSGY-----TCHFIRPGWKLPRRATAGQ--
MAV_5159|M.avium_104 ----DFWEAEPEHQDYLQRYPNGY-----TCHYIRPGWKLPRRATSGS--
MLBr_02647|M.leprae_Br4923 ----DFWEAEPEHQDYLQHYPNGY-----TCHFVRPNWKLPRRAPADAKA
Mflv_1105|M.gilvum_PYR-GCK ----DFWEAEPEHQDYLERYPTGY-----TCHFPRPGWKLPKRAEV----
Mvan_5709|M.vanbaalenii_PYR-1 ----EFWEAEPEHQDYLERYPSGY-----TCHFPRPGWKLPKRAEV----
MSMEG_6477|M.smegmatis_MC2_155 ----DFWEAEPEHQDYLVHYPNGY-----TCHFPRPGWKLPRRETASQ--
TH_0081|M.thermoresistible__bu ----TFWEAEPEHQDYLQRFPNGY-----TCHYPRPNWKLTVRSGIRGR-
MAB_0120|M.abscessus_ATCC_1997 HASRTFFYAEEYHQQYLAKNPNGYCGLGGTSVSCPIGLDVPPGGPAEA--
*: ** **.** : *.** *. . :.
Mb0142c|M.bovis_AF2122/97 ASLSPELGT
Rv0137c|M.tuberculosis_H37Rv ASLSPELGT
MMAR_0347|M.marinum_M ---------
MUL_4773|M.ulcerans_Agy99 ---------
MAV_5159|M.avium_104 ---------
MLBr_02647|M.leprae_Br4923 DS-------
Mflv_1105|M.gilvum_PYR-GCK ---------
Mvan_5709|M.vanbaalenii_PYR-1 ---------
MSMEG_6477|M.smegmatis_MC2_155 ---------
TH_0081|M.thermoresistible__bu ---------
MAB_0120|M.abscessus_ATCC_1997 ---------