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TGPHNDTESPHARPISVAELLARNGTIGAPAVSRRRRRRTDSDAVTVAELTCDIPIIHDDHADEQHLAAT HAHRANIGVRVVEPAAQSPLEPVCEGIVAEPPVDDHGHVPPGCWSAPEPRWPKSPPLTHLRTGLQRSACS RPLPHLGDVRHPVAPDSIAQKQSDAEGMSPDPVEPFADIPVDVMGSEVRAAELVAEESAYARYNLQMSAG ALFSGHTLTNELAERRGDEHAAGGLLAVGIDLDEDHLDLHTDLAGITSPARGWQSRFEALWRGSLIVLQS ILAVVFGAGLFVAFDQLWRWNSIVALVLSVLVILGLVVGVRVVRRTEDIASTLIAVVVGALITLGPLALS LQSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02433 | - | - | 100% (355) | hypothetical protein MLBr_02433 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0508 | - | 2e-81 | 53.61% (360) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_0078 | - | 1e-34 | 47.44% (215) | hypothetical protein Mflv_0078 |
| M. tuberculosis H37Rv | Rv0497 | - | 2e-81 | 53.61% (360) | transmembrane protein |
| M. abscessus ATCC 19977 | MAB_4012c | - | 2e-20 | 28.42% (292) | hypothetical protein MAB_4012c |
| M. marinum M | MMAR_0823 | - | 8e-86 | 52.08% (384) | transmembrane protein |
| M. avium 104 | MAV_4655 | - | 6e-98 | 60.11% (356) | hypothetical protein MAV_4655 |
| M. smegmatis MC2 155 | MSMEG_0940 | - | 2e-47 | 39.12% (386) | hypothetical protein MSMEG_0940 |
| M. thermoresistible (build 8) | TH_0882 | - | 4e-52 | 41.38% (377) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_4567 | - | 2e-86 | 52.34% (384) | transmembrane protein |
| M. vanbaalenii PYR-1 | Mvan_0834 | - | 4e-50 | 39.61% (409) | hypothetical protein Mvan_0834 |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02433|M.leprae_Br4923 MTGPHNDTESPHARPISVAELLARNGTIGAPAVSRRRRRR-TDSDAVTVA
MAV_4655|M.avium_104 MTGPHSETESPGTRPISVAELLARNGTIGAPAVTRRRRRRRGDSDAVTVA
Mb0508|M.bovis_AF2122/97 MTGPHPETESSGNRQISVAELLARQGVTGAP--ARRRRRRRGDSDAITVA
Rv0497|M.tuberculosis_H37Rv MTGPHPETESSGNRQISVAELLARQGVTGAP--ARRRRRRRGDSDAITVA
MMAR_0823|M.marinum_M MTGPHSETEDT--KQISVAELLARNGNVGAPAVTRRRRRRRGDTDSITVA
MUL_4567|M.ulcerans_Agy99 MTGPHSETEDT--KQISVAELLARNGNVGAPAVTRRRRRRRGDTDSITVA
Mflv_0078|M.gilvum_PYR-GCK MTG--TEDSNSSTRPISVAELLAKNGTIGAPPVGGRRRRRRGNSDAVTVA
Mvan_0834|M.vanbaalenii_PYR-1 MTG--SDDS-YSTRPISVAELLAKNGTIGSPPVGGRRRRRRGNADAVTVA
MSMEG_0940|M.smegmatis_MC2_155 MTG--PEDSQTPSRPISVAELLAKNGTIGAPPVGGRRRRRRGNADAVTVA
TH_0882|M.thermoresistible__bu MTE--PEDS---NRPISVAELLARNGTIGAPPVGGRRRRRRGNADAITVA
MAB_4012c|M.abscessus_ATCC_199 -----MTESDDTQRPVSVAELLARNG-AAEGKISGHRRRMRGNADAIPVA
. : :*******::* . :*** ::*::.**
MLBr_02433|M.leprae_Br4923 ELTCDIPIIHDDHA---------------DEQHLAATH----------AH
MAV_4655|M.avium_104 ELTGEIPVIRDDEP---------------DDQPGATDT----------VD
Mb0508|M.bovis_AF2122/97 ELTGEIPIIRDDHH---------------HAGPDAHAS---------QSP
Rv0497|M.tuberculosis_H37Rv ELTGEIPIIRDDHH---------------HAGPDAHAS---------QSP
MMAR_0823|M.marinum_M ELTGEIPIIRDDHHD-------------ERSAPSAPAETTETVAPTSQAK
MUL_4567|M.ulcerans_Agy99 ELTGEIPIIRDDHHD-------------ERSAPSAPAETTETVAPTSQAK
Mflv_0078|M.gilvum_PYR-GCK ELTGEIPIIRPDDPPPAPVTAPETVAEPIEEAPAEAEVEVEAEAEVEAES
Mvan_0834|M.vanbaalenii_PYR-1 ELTGEIPIVRPDEP------------TPVEEQPGEPEPEPEQATPTNGAV
MSMEG_0940|M.smegmatis_MC2_155 ELTGEIPVITDDDS-----------APQTSRRQRERDTSLEETTVVEAVP
TH_0882|M.thermoresistible__bu ELTGEIPVVGDDTE------------PEDAQKDGSGPDGSGRAAPVETPA
MAB_4012c|M.abscessus_ATCC_199 ELTGEIPVIRDKKGG--------RARPNPSPAAETAAPEATKAPEAAAPS
*** :**:: .
MLBr_02433|M.leprae_Br4923 RANIGVRVVEPAAQSPLEP---VCEGIVAEPPVDDH-----GHV-----P
MAV_4655|M.avium_104 TA------------APAQP---VAE--PAEPVAEDE-----PKT-----P
Mb0508|M.bovis_AF2122/97 AANGRVQVGEAAPQSPAEP---VAEQVAEEPT-----------------R
Rv0497|M.tuberculosis_H37Rv AANGRVQVGEAAPQSPAEP---VAEQVAEEPT-----------------R
MMAR_0823|M.marinum_M PGNGRVEVDEPAPASRVQPESVVAPAEATEPPQAAEEPAAGQAG-----R
MUL_4567|M.ulcerans_Agy99 PGNGRVEVDEPAPASRVQPESVVAPAEATEPPQAAEEPAAGQAG-----R
Mflv_0078|M.gilvum_PYR-GCK EVEAEVEADTAADVEAEDTDVEDATDVEVEATDDVEAPDVEAEAPADVVD
Mvan_0834|M.vanbaalenii_PYR-1 DEAASVEPDGELVEPAEDTVTAEDENGETEP--EAES-AIEAEP-----E
MSMEG_0940|M.smegmatis_MC2_155 ---AREEAPQAAPEKTPETEPRPARNGATPR----EAAVVADQP-----A
TH_0882|M.thermoresistible__bu ERTDEQELPG--PTGRTDLPKRETPTPAPDRDRTGQDRSAHRAP-----R
MAB_4012c|M.abscessus_ATCC_199 ETRSYLRSNEDALFGGDSMADEAARRGPSTPSTPAQPSSMASSLRSIFPP
.
MLBr_02433|M.leprae_Br4923 PGCWSAPEPRWPKSPPLTHLR---------TGLQRSACSRPLPHLGDVRH
MAV_4655|M.avium_104 --YWSEPEPRWPKSPPQPKRA---------PGPERSAYPRPLPEPG----
Mb0508|M.bovis_AF2122/97 TVYWSQPEPRWPKSPPQDRRE---------SGPELSEYPRPLRHTHS---
Rv0497|M.tuberculosis_H37Rv TVYWSQPEPRWPKSPPQDRRE---------SGPELSEYPRPLRHTHS---
MMAR_0823|M.marinum_M AAYWSEPEPRWPKSEPITRTK---------AGPERSEYPRPLRHTG----
MUL_4567|M.ulcerans_Agy99 AAYWSEPEPRWPKSEPITRTK---------AGPERSEYPRPLRHTG----
Mflv_0078|M.gilvum_PYR-GCK TDVQAEATDVDVEAETVEQVA---------PVAPPAAEPSRSRRFGFLR-
Mvan_0834|M.vanbaalenii_PYR-1 LEDDEYAKAVAEYAAHMEQRG---------TEPEETAEPAR--RFGFGR-
MSMEG_0940|M.smegmatis_MC2_155 PDAGAARDAEADYDAHLKTRE---------IDPEPVEFRPRPRRNQFAS-
TH_0882|M.thermoresistible__bu RPAVADSDPDEMVPDPLDDGE---------DAFESPVDLADAPEIDYGP-
MAB_4012c|M.abscessus_ATCC_199 TPTPATRPGEPRKSIDFNDATGVISPVTSAPTSEPTPKPTPKPEAAKPVT
.
MLBr_02433|M.leprae_Br4923 PVAPDSIA---------QKQSDAEGMSPDPVEPFADIPVDVMGSEVRAAE
MAV_4655|M.avium_104 -PSANGTG---------RRSSGAEDMSPDPMDHYADIPVDVMDSEVREAE
Mb0508|M.bovis_AF2122/97 ---DRAPA---------GPPSGAEHMSPDPVEHYPDLWVDVLDTEVG---
Rv0497|M.tuberculosis_H37Rv ---DRAPA---------GPPSGAEHMSPDPVEHYPDLWVDVLDTEVG---
MMAR_0823|M.marinum_M ---DSDAA---------GQGPGAEDMSPDPVGHYGDTSVDVSDSEAES--
MUL_4567|M.ulcerans_Agy99 ---DSDAA---------GQGPGAEDMSPDPVGHYGDTSVDVSDSEAES--
Mflv_0078|M.gilvum_PYR-GCK --LGRRSAPAAVTPVAETSVAEVPADQVDTVDDAPVAEETAEIEKTESGE
Mvan_0834|M.vanbaalenii_PYR-1 --FGRK-----------SSTVDAEQWTPDPVDEDTLDSD-VEIDTDED--
MSMEG_0940|M.smegmatis_MC2_155 --GTREYT---------PSGTGAEQMSPDPLDD--LDDGAPDTGLDSG--
TH_0882|M.thermoresistible__bu --ANFD------------DDADGPQERVEVAERRPWSRSTHDELFGGP--
MAB_4012c|M.abscessus_ATCC_199 PVPPAAPSAPPATPPAPVSRPVEPEPEPEPEPEPEAVVQPEAEPEPDARP
:
MLBr_02433|M.leprae_Br4923 LVAEESAYARYNLQMSAGALF-----------------------------
MAV_4655|M.avium_104 PALEDSAYVRSYLQSDS---------------------------------
Mb0508|M.bovis_AF2122/97 -EAEAETEVR---EAQPGR-------------------------------
Rv0497|M.tuberculosis_H37Rv -EAEAETEVR---EAQPGR-------------------------------
MMAR_0823|M.marinum_M -EVEDSAYVRSFLQASEGISD-----------------------------
MUL_4567|M.ulcerans_Agy99 -EVEDSAYVRSFLQASEGISD-----------------------------
Mflv_0078|M.gilvum_PYR-GCK TAEDAIAEEPSDTITEDAHDEDLHAEDLEPAFDDEDLDDRDSDELPSYLR
Mvan_0834|M.vanbaalenii_PYR-1 LTETEIEDLDDELALRDTHDT-LIGADVEIEDEDE---DEDVDELPSYLR
MSMEG_0940|M.smegmatis_MC2_155 -FEADIAD-DTGPDRRDARDA-------------------------SYPL
TH_0882|M.thermoresistible__bu --TVADRDTPFDLDTDDVDDT--------------------------DLE
MAB_4012c|M.abscessus_ATCC_199 EVIADEYEDDAECEEDDGEYG-------------------RSTAVEWNSH
MLBr_02433|M.leprae_Br4923 ---SGHTLTNELAERRGDEHAAGGLLAVG-----IDLDEDHLDLHTDLAG
MAV_4655|M.avium_104 ------ALDDDLDEDLDDDHADAATLTD------EDLDAAHLEDEDAEAA
Mb0508|M.bovis_AF2122/97 ----------------GERHAAA--------------AAAGTDVEGDGAA
Rv0497|M.tuberculosis_H37Rv ----------------GERHAAA--------------AAAGTDVEGDGAA
MMAR_0823|M.marinum_M ---QALYGGQSLADEVARRRGES--------------SPSTFDEEEAEAD
MUL_4567|M.ulcerans_Agy99 ---QALYGGQSLADEVARRRGES--------------SPSTFDEEEAEAD
Mflv_0078|M.gilvum_PYR-GCK SSEEPLFGGQSVVDELARQGDRSSRADTVEDRDAAVETVDADETDDDLVD
Mvan_0834|M.vanbaalenii_PYR-1 STEEPLFGGQTVADDLARRGRRPT------------EEHDEDE-DEDLTD
MSMEG_0940|M.smegmatis_MC2_155 GS---LFGGPSVDDDLDRDLERDL-------------DREDDEYADDLAD
TH_0882|M.thermoresistible__bu GDLGAEFDETDDETDLDEDLDENL---------------DEEVVEDDTAD
MAB_4012c|M.abscessus_ATCC_199 DAEHDVEGAENDYDENDYQLEHELQELVNEHGSPVDTEASQLADVETEKK
MLBr_02433|M.leprae_Br4923 IT-SPARGWQSRFEALWRGSLIVLQSILAVVFGAGLFVAFDQLWRWNSIV
MAV_4655|M.avium_104 HP-APG-----RLEAIWRGSVVVLQSILAVAFGAGLFVAFDQLWRWNSIV
Mb0508|M.bovis_AF2122/97 EA-RVARRALDVVPTLWRGALVVLQSILAVAFGAGLFIAFDQLWRWNSIV
Rv0497|M.tuberculosis_H37Rv EA-RVARRALDVVPTLWRGALVVLQSILAVAFGAGLFIAFDQLWRWNSIV
MMAR_0823|M.marinum_M EE-QGARPLSGKLAALWRGTLVVLQSILAVVFGAGLFIAFDQLWRWNSIV
MUL_4567|M.ulcerans_Agy99 EE-QAARPLSGKLAALWRGTLVVLQSILAVVFGAGLFIAFDQLWRWNSIV
Mflv_0078|M.gilvum_PYR-GCK EPDDHDAPRT--MSPLVSALWIIGQSVIAVVFGAGLFVAFDQLWKWNNII
Mvan_0834|M.vanbaalenii_PYR-1 EA--YGEPRR--MSSFVHGLWIVGQCIIAVIFGAGLFVAFDQLWKWNNII
MSMEG_0940|M.smegmatis_MC2_155 ELDEDDEVDEDEGSPLVRGLWVVAQCVIAVAFGAGLFVAFDQLWKWNTIV
TH_0882|M.thermoresistible__bu VG--AGEGSR--LSAILRGALVVGQCLLAVAFGAGLFLGFDQLWRWNSIV
MAB_4012c|M.abscessus_ATCC_199 TDAEAKAERKEKIKTYLQGGWIAAQYLLAAAAGAGLFFGFRELWSWNQGI
. . : * ::*. *****..* :** ** :
MLBr_02433|M.leprae_Br4923 ALVLSVLVILGLVVGVRVVRRTEDIASTLIAVVVGALITLGPLALSLQSG
MAV_4655|M.avium_104 ALVLSVLVILGLVVGVRVVRKTEDIASTLIAVAVGALITLGPLALSLQSG
Mb0508|M.bovis_AF2122/97 ALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALITLGPLAL-LQSG
Rv0497|M.tuberculosis_H37Rv ALVLSVMVILGLVVSVRAVRKTEDIASTLIAVAVGALITLGPLAL-LQSG
MMAR_0823|M.marinum_M ALVLSVLVILGLVVGVRVVRKTEDIGSTLIAVAVGALITLGPLAL-LQSG
MUL_4567|M.ulcerans_Agy99 ALVLSVLVILGLVVGVRVVRKTEDIGSTLIAVAVGALITLGPLAL-LQSG
Mflv_0078|M.gilvum_PYR-GCK ALVLSVLVILGLVVGVRLVRKTEDIGSTLIAVAVGALVTLGPLAL-LQSG
Mvan_0834|M.vanbaalenii_PYR-1 ALVLSVLVILGLVVGVRVVRKTEDIGSTLIAVAVGALVTLGPLAL-LQSG
MSMEG_0940|M.smegmatis_MC2_155 ALVLGVLVILGLAGGVRVVRKTEDIGSTLTAVAVGALVTFGPLAL-LQAS
TH_0882|M.thermoresistible__bu TLVLSMLVILGLVAGVRVVRKTEDITSTMIAVVVGALVTFGPLALQLQAS
MAB_4012c|M.abscessus_ATCC_199 ALVLGVLFIAILVASLWVIRKTVDLISILIAIVVGALIAFGPLVLMLQAV
:***.::.* *. .: :*:* *: * : *:.****:::***.* **:
MLBr_02433|M.leprae_Br4923 -
MAV_4655|M.avium_104 -
Mb0508|M.bovis_AF2122/97 -
Rv0497|M.tuberculosis_H37Rv -
MMAR_0823|M.marinum_M -
MUL_4567|M.ulcerans_Agy99 -
Mflv_0078|M.gilvum_PYR-GCK -
Mvan_0834|M.vanbaalenii_PYR-1 -
MSMEG_0940|M.smegmatis_MC2_155 -
TH_0882|M.thermoresistible__bu -
MAB_4012c|M.abscessus_ATCC_199 D