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M. leprae Br4923 MLBr_01988 (-)

annotation: putative integral membrane protein
coordinates: 2375630 - 2376343
length: 237

DCEVAREALSARLDGEREAVPSVRVDEHLGECSACRAWFDQVADQARDLRQLVDSRPAITPVDALGIVAP
PRRRRPLMTWQRWALLCVGIAQIVLATVQGLGVSVGLTHDRAMSFGSYLLHESTAWSASLGVIMMAAVLW
PGVAAGLAGVLTVFVGLLTVYVVVDVVAGATITLRILMHLPVAIGAVLAIAVWRHSSTPRPTFDDEVDVD
LDIVLPRNASRGRRRGHLWPTDGSAV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01988--100% (237)putative integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0096c-7e-9270.34% (236) hypothetical protein Mb0096c
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv0093c-7e-9270.34% (236) hypothetical protein Rv0093c
M. abscessus ATCC 19977MAB_3430c-5e-2836.24% (229) hypothetical protein MAB_3430c
M. marinum MMMAR_0263-4e-8264.14% (237) hypothetical protein MMAR_0263
M. avium 104MAV_2426-5e-2334.68% (173) RNA polymerase sigma factor SigC
M. smegmatis MC2 155-----
M. thermoresistible (build 8)TH_4169-3e-4842.48% (266) PUTATIVE putative putative conserved hypothetical protein
M. ulcerans Agy99MUL_4851-7e-8162.24% (241) hypothetical protein MUL_4851
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb0096c|M.bovis_AF2122/97           MLAQATTAGSFNHHASTVLQGRRGVPAAMWSEPAGAIRRHCATIDGMDCE
Rv0093c|M.tuberculosis_H37Rv        MLAQATTAGSFNHHASTVLQGCRGVPAAMWSEPAGAIRRHCATIDGMDCE
MLBr_01988|M.leprae_Br4923          ----------------------------------------------MDCE
MMAR_0263|M.marinum_M               ----------------------------------------------MDCE
MUL_4851|M.ulcerans_Agy99           ----------------------------------------------MDCE
TH_4169|M.thermoresistible__bu      ----------------------------------------------MDCH
MAB_3430c|M.abscessus_ATCC_199      ----------------------------------------------MNCQ
MAV_2426|M.avium_104                --------------------------------------------------
                                                                                      

Mb0096c|M.bovis_AF2122/97           VAREALSARLDGERAPVPSARVDEHLGECSACRAWFTQVASQAGDLRRLA
Rv0093c|M.tuberculosis_H37Rv        VAREALSARLDGERAPVPSARVDEHLGECSACRAWFTQVASQAGDLRRLA
MLBr_01988|M.leprae_Br4923          VAREALSARLDGEREAVPSVRVDEHLGECSACRAWFDQVADQARDLRQLV
MMAR_0263|M.marinum_M               VAREALSARLDGEREPVPSARVDEHLDECGACGLWFEQVAGQASRLQRLI
MUL_4851|M.ulcerans_Agy99           VARETLSARLDGEREPVPSARVDEHLDECGACGLWFEQVAGQASRLQRLI
TH_4169|M.thermoresistible__bu      VAREALSARIDNEQEPVPPARVDEHLESCQACAAWYLLVSRQAAEIRRLA
MAB_3430c|M.abscessus_ATCC_199      EVREQLSAWVDGEQASVARKRLDEHVLSCASCREWLGRARGLDRQFAYAR
MAV_2426|M.avium_104                -------------------------------------MTPGEGPDLVDKI
                                                                          .      :    

Mb0096c|M.bovis_AF2122/97           ES--RPVVP----PVGRLGIRRAPR-RQHSPMTWRRWALLCVGIAQIALG
Rv0093c|M.tuberculosis_H37Rv        ES--RPVVP----PVGRLGIRRAPR-RQHSPMTWRRWALLCVGIAQIALG
MLBr_01988|M.leprae_Br4923          DS--RPAIT----PVDALGIVAPPR-RRRPLMTWQRWALLCVGIAQIVLA
MMAR_0263|M.marinum_M               ES--RPVIG----AVDLTGIRPTPQPRERKRMSWQRWALLFVGIAQVAVG
MUL_4851|M.ulcerans_Agy99           ES--RPVIG----AVDLAGIRPTPQPRERKRMSWQRWALLCVGIAQVAVG
TH_4169|M.thermoresistible__bu      GAT-RSAIGLAPAPRNRRRLPRIPVLTRPVRVPWPRWALGVVGVLQLALG
MAB_3430c|M.abscessus_ATCC_199      SAPTRDLTGQILAAAAVEPLTPMARYAHWARHNINRCALVLIGLLQLGVA
MAV_2426|M.avium_104                MAS----IG--------EQPTGRPAWMRWLRSHYRRWGLIGVGLFQVAIA
                                     :                     .   .       * .*  :*: *: :.

Mb0096c|M.bovis_AF2122/97           TVQGFGLDVGLTHQHPTGA----GTHLLNESTSWSIALGVIMVGAALWPS
Rv0093c|M.tuberculosis_H37Rv        TVQGFGLDVGLTHQHPTGA----GTHLLNESTSWSIALGVIMVGAALWPS
MLBr_01988|M.leprae_Br4923          TVQGLGVSVGLTHDRAMSF----GSYLLHESTAWSASLGVIMMAAVLWPG
MMAR_0263|M.marinum_M               IVQGLGFSVGLGHHYVIGS----GNHLLNESTAWTIALGVAMVVAAIWPG
MUL_4851|M.ulcerans_Agy99           IVQGLGFSLGLGHHYVIGS----GNHLLNESTAWTIALGVAMVVAAIWPG
TH_4169|M.thermoresistible__bu      VAQATGTNFGMLAHHGTHHGAHQGVHLLNESTAWSLALGAVMIAAAVRPV
MAB_3430c|M.abscessus_ATCC_199      GMQVAGIDFGMVSAHHHGAMT--GAHLMNESTAWVVALGVAMVIAGVRPA
MAV_2426|M.avium_104                AAQISGIDFGMVAGHMHGAMS--GEHLMHESTAWLLALGLAMIAAGVWPA
                                      *  * ..*:            * :*::***:*  :**  *: * : * 

Mb0096c|M.bovis_AF2122/97           AAAGLAGVLTAFVAILTGYVIVDALSGAVSTT----RILTHLPVVIGAVL
Rv0093c|M.tuberculosis_H37Rv        AAAGLAGVLTAFVAILTGYVIVDALSGAVSTT----RILTHLPVVIGAVL
MLBr_01988|M.leprae_Br4923          VAAGLAGVLTVFVGLLTVYVVVDVVAGATITL----RILMHLPVAIGAVL
MMAR_0263|M.marinum_M               AAGGLAGVLMVFVAVLSVYVVVDALSGAVTTS----RVLTHLPVLLGTVL
MUL_4851|M.ulcerans_Agy99           AAEGLAGVLMVFVAVLSVYVVVDALSGAVTTSRVLTRVLTHLPVLLGTVL
TH_4169|M.thermoresistible__bu      AATGLAGVSTVFTVALTVYVIADWLAGLVTPA----RVLSHLPVVLGTVL
MAB_3430c|M.abscessus_ATCC_199      AAAGMATVLGAFALVLTGYVINDAVNDQVTLA----RIISHLPVLLGLIF
MAV_2426|M.avium_104                SASGVAAITGVYSVALLGYVIVDAFDGEVTAT----RIASHMPLLLGLAF
                                     * *:* :  .:   *  **: * . . .       *:  *:*: :*  :

Mb0096c|M.bovis_AF2122/97           AIMVWRSASGP-RPR------PDAVAAEPDIVLPDNAS--RGRRRGHLWP
Rv0093c|M.tuberculosis_H37Rv        AIMVWRSASGP-RPR------PDAVAAEPDIVLPDNAS--RGRRRGHLWP
MLBr_01988|M.leprae_Br4923          AIAVWRHSSTP-RPTF-----DDEVDVDLDIVLPRNAS--RGRRRGHLWP
MMAR_0263|M.marinum_M               AIMVWRSRGAP-RPA------PDVLADEPDIVLPQNAS--RGRRHGHLWP
MUL_4851|M.ulcerans_Agy99           AVMVWRSRGAP-RPA------PDVLADEPDIVLPQNAS--RGRRHGHLWP
TH_4169|M.thermoresistible__bu      ALLVWRAQRDPGDPWDGSIGLPDGAGEAEPVEDPSGPGDLEPTGRRHLWP
MAB_3430c|M.abscessus_ATCC_199      ALLVLRDYRAGRTPP----------NQHRAVFLDEVAA-----GERHLRS
MAV_2426|M.avium_104                ALLVARERVGSRRPGS-----SDATADAGFAAWAADAP--AGRRRGHLRP
                                    *: * *       *                      .       . ** .

Mb0096c|M.bovis_AF2122/97           TDGSAA--------------------------------------------
Rv0093c|M.tuberculosis_H37Rv        TDGSAA--------------------------------------------
MLBr_01988|M.leprae_Br4923          TDGSAV--------------------------------------------
MMAR_0263|M.marinum_M               TDGSAA--------------------------------------------
MUL_4851|M.ulcerans_Agy99           TDGSAA--------------------------------------------
TH_4169|M.thermoresistible__bu      VNRSAA--------------------------------------------
MAB_3430c|M.abscessus_ATCC_199      ADNSAA--------------------------------------------
MAV_2426|M.avium_104                INRAAPDPTASSTTTRRRIGKPAQLRWLGMIAPSDDEAVTELALSAARGN
                                     : :*                                             

Mb0096c|M.bovis_AF2122/97           --------------------------------------------------
Rv0093c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01988|M.leprae_Br4923          --------------------------------------------------
MMAR_0263|M.marinum_M               --------------------------------------------------
MUL_4851|M.ulcerans_Agy99           --------------------------------------------------
TH_4169|M.thermoresistible__bu      --------------------------------------------------
MAB_3430c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2426|M.avium_104                ARALEAFIKATQQDVWRFVAYLCDAGSADDLTQETFLRAIGAIERFSGRS
                                                                                      

Mb0096c|M.bovis_AF2122/97           --------------------------------------------------
Rv0093c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01988|M.leprae_Br4923          --------------------------------------------------
MMAR_0263|M.marinum_M               --------------------------------------------------
MUL_4851|M.ulcerans_Agy99           --------------------------------------------------
TH_4169|M.thermoresistible__bu      --------------------------------------------------
MAB_3430c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2426|M.avium_104                SARTWLLSIARRVVADHIRHLQSRPRAAVGADPEHVLRTDRHARGFEDLV
                                                                                      

Mb0096c|M.bovis_AF2122/97           --------------------------------------------------
Rv0093c|M.tuberculosis_H37Rv        --------------------------------------------------
MLBr_01988|M.leprae_Br4923          --------------------------------------------------
MMAR_0263|M.marinum_M               --------------------------------------------------
MUL_4851|M.ulcerans_Agy99           --------------------------------------------------
TH_4169|M.thermoresistible__bu      --------------------------------------------------
MAB_3430c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_2426|M.avium_104                EVTTMIAGLNPEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARD
                                                                                      

Mb0096c|M.bovis_AF2122/97           -------------
Rv0093c|M.tuberculosis_H37Rv        -------------
MLBr_01988|M.leprae_Br4923          -------------
MMAR_0263|M.marinum_M               -------------
MUL_4851|M.ulcerans_Agy99           -------------
TH_4169|M.thermoresistible__bu      -------------
MAB_3430c|M.abscessus_ATCC_199      -------------
MAV_2426|M.avium_104                ALLADGERNDLTG