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M. leprae Br4923 MLBr_01171 (-)

annotation: hypothetical protein MLBr_01171
coordinates: 1368532 - 1369248
length: 238

VGAPSACGGGSALMTLPEKNLGYKPETETNRRLRWMVGGVTILTFMALLYLVELIDQLTRHSLDNNGIRL
LKTDVLWGISFAPVLHANWQHLVANTIPLLVLGFLIALAGLSRFIWVTAMVWIFGGSATWLIGNMGSSFG
PTDHIGVSGLIFGWLAFLLVFGLFVRRGWDIIGCMVLFAYGGVLLGVMPVLGRCGGVSWQGHLCGAISGV
VAAYLLSAPERKTRALKEAGTDSPRLKT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01171--100% (238)hypothetical protein MLBr_01171

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1372-5e-9573.89% (226) integral membrane protein
M. gilvum PYR-GCKMflv_2355-3e-6962.07% (203) rhomboid family protein
M. tuberculosis H37RvRv1337-5e-9573.89% (226) integral membrane protein
M. abscessus ATCC 19977MAB_1481-1e-6158.10% (210) hypothetical protein MAB_1481
M. marinum MMMAR_4059-3e-9274.88% (215) integral membrane protein
M. avium 104MAV_1554-2e-8769.68% (221) rhomboid family protein
M. smegmatis MC2 155MSMEG_4904-5e-7863.68% (212) rhomboid family protein
M. thermoresistible (build 8)TH_1018-2e-6560.10% (203) PROBABLE INTEGRAL MEMBRANE PROTEIN
M. ulcerans Agy99MUL_4822-2e-0630.67% (150) serine protease
M. vanbaalenii PYR-1Mvan_4290-3e-7061.72% (209) rhomboid family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2355|M.gilvum_PYR-GCK          ---------------MTGTGGYPLQPAGPAKR------PVWVVGGVTVVS
Mvan_4290|M.vanbaalenii_PYR-1       ---------------MTGIGGHPGIPAEPKKR------PAWMVGGLTVLS
MAB_1481|M.abscessus_ATCC_1997      ---------------MTGYGGGPDYPGSPSSRRERSGRPQWVTGGVLVAS
TH_1018|M.thermoresistible__bu      -----------------------------------------VTGGLTILT
Mb1372|M.bovis_AF2122/97            MGMTPRRKRRGGAVQITRPTGRPRTPTTQTTKR-----PRWVVGGTTILT
Rv1337|M.tuberculosis_H37Rv         MGMTPRRKRRGGAVQITRPTGRPRTPTTQTTKR-----PRWVVGGTTILT
MMAR_4059|M.marinum_M               ---------------MAR---HPRTPATQPEER-----PRWVTGGATILT
MLBr_01171|M.leprae_Br4923          MGA-PSACGGGSALMTLPEKNLGYKPETETNRR-----LRWMVGGVTILT
MAV_1554|M.avium_104                MG-----------------KTTGRAPAAQTKKR-----STAVAGATTIVT
MSMEG_4904|M.smegmatis_MC2_155      -------------------MTLPTGPAPKKNKS-----PAWKTGGITILT
MUL_4822|M.ulcerans_Agy99           --MRSGAVGHQCVECVRADARTVRQPRTQFGGR------QRSVTPVVTFS
                                                                              .      :

Mflv_2355|M.gilvum_PYR-GCK          FVVLLWLIELFDTLTGHRLDDNGIRP--LETDGLTGILVAPLLHSNWEHL
Mvan_4290|M.vanbaalenii_PYR-1       FVVLLWVIELFDSLTGHRLDGNGIRP--LETDGLAGILFAPLLHSNWEHL
MAB_1481|M.abscessus_ATCC_1997      FVALLYVVEGIDSVTGHRLDENGIRP--LETDGLDGILFAPLLHANWGHL
TH_1018|M.thermoresistible__bu      FVALLYVIEAYDAVTGNQLDQNGIRP--LDTDGLTGVLLAPLLHGGWEHL
Mb1372|M.bovis_AF2122/97            FVALLYLVELIDQLSGSRLDVNGIRP--LKTDGLWGVIFAPLLHANWHHL
Rv1337|M.tuberculosis_H37Rv         FVALLYLVELIDQLSGSRLDVNGIRP--LKTDGLWGVIFAPLLHANWHHL
MMAR_4059|M.marinum_M               FVALLYLVELIDQLTRHSLDLNGIRP--LQTDGLWGIIFAPLLHANWAHL
MLBr_01171|M.leprae_Br4923          FMALLYLVELIDQLTRHSLDNNGIRL--LKTDVLWGISFAPVLHANWQHL
MAV_1554|M.avium_104                FVALLYLVELIDQLTRHALDVHGIRP--QRLDGLWGILFAPVLHESWQHL
MSMEG_4904|M.smegmatis_MC2_155      FVALLYVVELADQLSGGRLDRNGIRP--LETDGLWGVLFAPLLHANWEHL
MUL_4822|M.ulcerans_Agy99           LIAVSVLVFVLQLVVAGLGPHLALWPPAVADGQLYRLVTSAFMHYGRLHL
                                    ::.:  ::   : :        .:       . *  :  :..:* .  **

Mflv_2355|M.gilvum_PYR-GCK          IANTGPALVLG-FLMTLAGLSRFIFATAIIWFAGGLGTWLIGNVGAPT-Y
Mvan_4290|M.vanbaalenii_PYR-1       LANTVPALVLG-FLMTLAGLSRFIFATAIVWIVGGVGTWLIGNIGAHCPY
MAB_1481|M.abscessus_ATCC_1997      VANTVPALVLG-FLAAAAGVGRFLLATAIIWLLGGVGTWLIGNIGLPY--
TH_1018|M.thermoresistible__bu      MANTGPALVLG-FLMTLAGMSRFIFATAIIWILGGLGTWLIGDLGAPAG-
Mb1372|M.bovis_AF2122/97            MANTIPLLVLG-FLMTLAGLSRFVWATAIIWILGGLGTWLIGNVGSSCG-
Rv1337|M.tuberculosis_H37Rv         MANTIPLLVLG-FLMTLAGLSRFVWATAIIWILGGLGTWLIGNVGSSCG-
MMAR_4059|M.marinum_M               MANTVPLLVLG-FLMTLAGLARFVWATAIVWILGGFGTWLIGNVGSSCG-
MLBr_01171|M.leprae_Br4923          VANTIPLLVLG-FLIALAGLSRFIWVTAMVWIFGGSATWLIGNMGSSFG-
MAV_1554|M.avium_104                MANTVPLLVLG-FLMTLAGLARFVWATVIIWIVGGFGTWLIGNVGSSCG-
MSMEG_4904|M.smegmatis_MC2_155      MANTVPALVLG-FLVTLAGLARFVWATAIIWILGGIGTWLIGDVGGCPL-
MUL_4822|M.ulcerans_Agy99           VFNMWALYVVGPPLEMWLGRLRFGGLYALSALGGSVLVYLIAPLNTATA-
                                    : *  .  *:*  *    *  **    .:  : *.  .:**. :.     

Mflv_2355|M.gilvum_PYR-GCK          NGVIVETNHIGASGLIFGWLTFLIVFGFFTRTVWEIVVGVVVFFIYGGIL
Mvan_4290|M.vanbaalenii_PYR-1       VGVRCETNHIGASGLIFGWLAFLIVFGFFTRKVWEIVVGVVVLFVYGSVL
MAB_1481|M.abscessus_ATCC_1997      -----ETNHIGASGLIFGWLTYVIVRGFFNRSVGQILIGAVVLVLYGGVL
TH_1018|M.thermoresistible__bu      ----VSTVHIGASGLIFGWLTFLIVFGFFTRKVWQITVGIMVLLIYGSIL
Mb1372|M.bovis_AF2122/97            -----PTDHIGASGLIFGWLAFLLVFGLFVRKGWDIVIGLVVLFVYGGIL
Rv1337|M.tuberculosis_H37Rv         -----PTDHIGASGLIFGWLAFLLVFGLFVRKGWDIVIGLVVLFVYGGIL
MMAR_4059|M.marinum_M               -----PTDHIGASGLIFGWLAFLLVFGLFVRKVWDIIIGLAVLFFYGGIL
MLBr_01171|M.leprae_Br4923          -----PTDHIGVSGLIFGWLAFLLVFGLFVRRGWD-IIGCMVLFAYGGVL
MAV_1554|M.avium_104                -----PTDHIGASGLIFGWLAFLLVFGIFVRRVRDIIIGLAVMFAYGGVL
MSMEG_4904|M.smegmatis_MC2_155      -----PTNHIGASGLIFGWLTFLLVFGWFTRNAWQIVVGILVLLVYGGIL
MUL_4822|M.ulcerans_Agy99           ----------GASGAIFGLFGATFVVAKRLNLDIRWVVALIAINLAITFV
                                              *.** *** :   :* .   .      :.  .:     .:

Mflv_2355|M.gilvum_PYR-GCK          LGVLP--GTFG-VSWQGHLCGALAG--VLAAYLLSGPERK----------
Mvan_4290|M.vanbaalenii_PYR-1       LGVLP--GTPG-VSWQGHLSGAVAG--VLAAYLLSGPERK----------
MAB_1481|M.abscessus_ATCC_1997      WGVLP--GQFG-VSWQGHLSGAVAG--VLAAYWLSGRERK----------
TH_1018|M.thermoresistible__bu      LGVLP--GTFG-VSWQGHLCGAIAG--VIAAYVLSGPERR----------
Mb1372|M.bovis_AF2122/97            LGAMPVLGQCGGVSWQGHLSGAVAG--VVAAYLLSAPERK----------
Rv1337|M.tuberculosis_H37Rv         LGAMPVLGQCGGVSWQGHLSGAVAG--VVAAYLLSAPERK----------
MMAR_4059|M.marinum_M               LGALPRLGVCGGVSWQGHLCGALAG--VVAAYFLSAPERK----------
MLBr_01171|M.leprae_Br4923          LGVMPVLGRCGGVSWQGHLCGAISG--VVAAYLLSAPERK----------
MAV_1554|M.avium_104                LGAMPVLGLCGGVSWQGHLCGAIAG--VLAAYLLSEPERK----------
MSMEG_4904|M.smegmatis_MC2_155      WGAVPVLNGCGGVSWQGHLCGAIAG--VVAAYVLAGPERK----------
MUL_4822|M.ulcerans_Agy99           APAVG----SQLISWQGHVGGLITGALVAAAYVYAPRERRNFIQGAVTLT
                                      .:        :*****: * ::*  * ***  :  **:          

Mflv_2355|M.gilvum_PYR-GCK          ----------TRALR-RPVRPPSLNT-
Mvan_4290|M.vanbaalenii_PYR-1       ----------ARERR-KATN-PYLTT-
MAB_1481|M.abscessus_ATCC_1997      ----------VQAAR-GPGVPPRLTP-
TH_1018|M.thermoresistible__bu      ----------ARALR-RPVQPPRLTR-
Mb1372|M.bovis_AF2122/97            ----------ARALKRAGARSGHPKL-
Rv1337|M.tuberculosis_H37Rv         ----------ARALKRAGARSGHPKL-
MMAR_4059|M.marinum_M               ----------ARELKKAGERPSSPKT-
MLBr_01171|M.leprae_Br4923          ----------TRALKEAGTDSPRLKT-
MAV_1554|M.avium_104                ----------GRSGRKTGAVAPRPKT-
MSMEG_4904|M.smegmatis_MC2_155      ----------ARDSRKRSR--PYLTS-
MUL_4822|M.ulcerans_Agy99           VAVAFVVLIWWRTSELLAMFGGHLNLG
                                               :  .         .