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VCRTTLPGGLRVVTEHLPAVRSASVGVWVGVGSRDEGATVAGAAHFLEHLLFKSTSTRTAMDIAQAIDAV GGELNAFTAKEHTCYYAHVLDSDLELAVDLVADVVLNGRCAVDDVELERDVVLEEIAMRDDDPEDALGDM FLAALFGDHPVGRPVIGTMESVSAMTRTQLHSFHVRRYTPERMVVAVAGNVDHDEMVALVREHFGSRLIR GRQSAPPRKSTGRINGGPALTLGKRDAEQTHVLLGVRTPGRSWEHRWALSVLHTALGGGLSSRLFQEIRE TRGLAYSVYSALDIFADSGALSVYAACLPGRFADVMQVISEVLASVAGDGITEAECRIAKGSLRGGIILG LEDSNSWMSRLGRSELNYGKYRGIEHTLQQIDEVTVEQVNALAHQLLNKRYGAAVLGPYASKKTLPRQLR IMVN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00855 | pepR | - | 100% (424) | putative zinc protease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2805c | pepR | 0.0 | 84.32% (421) | zinc protease PEPR |
| M. gilvum PYR-GCK | Mflv_4022 | - | 0.0 | 74.76% (420) | peptidase M16 domain-containing protein |
| M. tuberculosis H37Rv | Rv2782c | pepR | 0.0 | 84.32% (421) | zinc protease PEPR |
| M. abscessus ATCC 19977 | MAB_3105c | - | 1e-165 | 70.76% (407) | hypothetical protein MAB_3105c |
| M. marinum M | MMAR_1926 | pepR | 0.0 | 84.36% (422) | zinc protease PepR |
| M. avium 104 | MAV_3675 | - | 0.0 | 83.85% (421) | protease |
| M. smegmatis MC2 155 | MSMEG_2657 | - | 0.0 | 77.38% (420) | peptidase, M16 family protein |
| M. thermoresistible (build 8) | TH_1284 | pepR | 0.0 | 75.66% (419) | PROBABLE ZINC PROTEASE PEPR |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2351 | - | 0.0 | 77.14% (420) | peptidase M16 domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4022|M.gilvum_PYR-GCK ---------------------------------MRRTRLPGGLRVVTEHI
Mvan_2351|M.vanbaalenii_PYR-1 MQRRQAAS------SQALRRGKRGGDAPDKSTAVRRTQLPGGLRVVTEHI
MSMEG_2657|M.smegmatis_MC2_155 -----------------------MTETRLETSQVRRTTLPGGLRVVTEYL
TH_1284|M.thermoresistible__bu ---------------------------------VRRTVLPGGLRVVTEYL
Mb2805c|M.bovis_AF2122/97 MPRRSP-------------------ADPAAALAPRRTTLPGGLRVVTEFL
Rv2782c|M.tuberculosis_H37Rv MPRRSP-------------------ADPAAALAPRRTTLPGGLRVVTEFL
MMAR_1926|M.marinum_M MPPRQA-------------------ADPAAVPALRRTTLPGGLRVVTEYL
MLBr_00855|M.leprae_Br4923 ---------------------------------MCRTTLPGGLRVVTEHL
MAV_3675|M.avium_104 MPPADSRRRAADSSTGALRAGKVVEAQPHPHAALRRSTLPGGLRVVTEYL
MAB_3105c|M.abscessus_ATCC_199 -------------------------------------------------M
:
Mflv_4022|M.gilvum_PYR-GCK PSVHSASVGVWVNVGSRDEGRSVAGAAHFLEHLLFKATPTRTAVQIAQAV
Mvan_2351|M.vanbaalenii_PYR-1 PSVHSASVGVWVNVGSRDEGRSVAGAAHFLEHLLFKATPTRTAVQIAQAV
MSMEG_2657|M.smegmatis_MC2_155 PYVRSASVGVWVGVGSRDEGRSVAGAAHFLEHLLFKSTPTRTAVDIAQTV
TH_1284|M.thermoresistible__bu PSVHSVSVGVWVGVGSRDEGPSVAGAAHFLEHLLFKSTPTRSAVDIAQAV
Mb2805c|M.bovis_AF2122/97 PAVHSASVGVWVGVGSRDEGATVAGAAHFLEHLLFKSTPTRSAVDIAQAM
Rv2782c|M.tuberculosis_H37Rv PAVHSASVGVWVGVGSRDEGATVAGAAHFLEHLLFKSTPTRSAVDIAQAM
MMAR_1926|M.marinum_M PAVRSASVGVWVGVGSRDEGTTVAGAAHFLEHLLFKSTPTRTAVDIAQAM
MLBr_00855|M.leprae_Br4923 PAVRSASVGVWVGVGSRDEGATVAGAAHFLEHLLFKSTSTRTAMDIAQAI
MAV_3675|M.avium_104 PAVRSASVGVWVGVGSRDEGATVAGAAHFLEHLLFKSTPTRTAVDIAQAM
MAB_3105c|M.abscessus_ATCC_199 PSVRSASVGVWVDVGSRDEGRSVAGAAHFLEHLLFKSTPTRSAADIAQSI
* *:*.******.******* :**************:*.**:* :***::
Mflv_4022|M.gilvum_PYR-GCK DAVGGELNAFTSREHTCYYAHVLDSDLELAVDLVADVVLNGRCEPDDVEV
Mvan_2351|M.vanbaalenii_PYR-1 DAVGGELNAFTAREHTCYYAHVLDSDLELAVDLVADVVLNGRCAPGDVEV
MSMEG_2657|M.smegmatis_MC2_155 DAVGGELNAFTAREHTCYYAHVLDSDLELAVDLVADVVLRGRCAAEDVEV
TH_1284|M.thermoresistible__bu DAVGGELNAFTAREHTCYYAHVLDADLALAIDLVADVVLNGRCAAADVEL
Mb2805c|M.bovis_AF2122/97 DAVGGELNAFTAKEHTCYYAHVLGSDLPLAVDLVADVVLNGRCAADDVEV
Rv2782c|M.tuberculosis_H37Rv DAVGGELNAFTAKEHTCYYAHVLGSDLPLAVDLVADVVLNGRCAADDVEV
MMAR_1926|M.marinum_M DAVGGELNAFTAKEHTCYYAHVLDNDLELAVELVADVVLNGRCAADDVEL
MLBr_00855|M.leprae_Br4923 DAVGGELNAFTAKEHTCYYAHVLDSDLELAVDLVADVVLNGRCAVDDVEL
MAV_3675|M.avium_104 DAVGGELNAFTAKEHTCYYAHVLDADLELAVDLVADVVLNGRCAAEDVEL
MAB_3105c|M.abscessus_ATCC_199 DAVGGELNAFTAREQTCYYAHVLDSDLELAIDLVADVVLRGRCASDDVEV
***********::*:********. ** **::*******.*** ***:
Mflv_4022|M.gilvum_PYR-GCK ERDVVLEEIAMRDDDPEDTLGDVFLSAMFGDHPVGRPVVGSVASIAGMTR
Mvan_2351|M.vanbaalenii_PYR-1 ERDVVLEEIAMRDDDPEDTLGDVFLSAMFGDHPVGRPVIGSVESISAMTR
MSMEG_2657|M.smegmatis_MC2_155 ERDVVLEEIAMRDDDPEDTLGDVFLSAMFGDHPVGRPVIGSIESISEMTR
TH_1284|M.thermoresistible__bu ERDVVLEEIAMRDDDPEDSLGDVFLEAMFGRHPVGRPVIGSVETVSAMTR
Mb2805c|M.bovis_AF2122/97 ERDVVLEEIAMRDDDPEDALADMFLAALFGDHPVGRPVIGSAQSVSVMTR
Rv2782c|M.tuberculosis_H37Rv ERDVVLEEIAMRDDDPEDALADMFLAALFGDHPVGRPVIGSAQSVSVMTR
MMAR_1926|M.marinum_M ERDVVLEEIAMRDDDPEDALADMFLTAMYGDHPVGRPVIGSTQSVSAMTR
MLBr_00855|M.leprae_Br4923 ERDVVLEEIAMRDDDPEDALGDMFLAALFGDHPVGRPVIGTMESVSAMTR
MAV_3675|M.avium_104 ERDVVLEEIAMRDDDPEDALGDMFLGALFGDHPVGRPVIGTARSVASMTR
MAB_3105c|M.abscessus_ATCC_199 ERDVVLEEIAMRDDDPEDLLGEAFLGALFGDHPIGRSVLGSSESISAMTR
****************** *.: ** *::* **:**.*:*: ::: ***
Mflv_4022|M.gilvum_PYR-GCK SQLHSFHVRRYTPDRMVVAVAGNIEHDEVVRLVRRHFGRHLVRGRSPVAP
Mvan_2351|M.vanbaalenii_PYR-1 SQLHSFHVRRYTPDRMVVAVAGNVEHDMVVKLVREHFGPRLERGRAPVPP
MSMEG_2657|M.smegmatis_MC2_155 AQLHSFHVRRYTPDRMVLAVAGNVDHDEVVALAREHFGRRLVQGRDAVPP
TH_1284|M.thermoresistible__bu AQLHSFHIRRYTPDRMVVAVAGNVDHDEVVALAHRHFGARLVPGRTPVPP
Mb2805c|M.bovis_AF2122/97 AQLQSFHLRRYTPERMVVAAAGNVDHDGLVALVREHFGSRLVRGRRPVAP
Rv2782c|M.tuberculosis_H37Rv AQLQSFHLRRYTPERMVVAAAGNVDHDGLVALVREHFGSRLVRGRRPVAP
MMAR_1926|M.marinum_M AQLHSFHMRRYTPDRMVVAVAGNVDHNQVVGLVREHFGPRLVRGRRPVAP
MLBr_00855|M.leprae_Br4923 TQLHSFHVRRYTPERMVVAVAGNVDHDEMVALVREHFGSRLIRGRQSAPP
MAV_3675|M.avium_104 TQLHSFHVRRYTPERMVVAVAGNVDHDEVVAMVREHFGPHLVRGRQPIAP
MAB_3105c|M.abscessus_ATCC_199 AQLHSFHVRRYRPERMVLAVAGNIEHDRVVRLARKYFKSHLDSSVRTVAP
:**:***:*** *:***:*.***::*: :* :.:.:* :* . . .*
Mflv_4022|M.gilvum_PYR-GCK RKGAGRVAGRPTLELVKRDAEQTHLSLGVRTPGRHWEHRWALSVLNTALG
Mvan_2351|M.vanbaalenii_PYR-1 RKGAGRVGGQPTLHLVSRDAEQTHLSLGVRTPGRHWDHRWALSVLNSALG
MSMEG_2657|M.smegmatis_MC2_155 RKGSGRVPGRPSLRVVERDGEQTHVSLGVRTPGRHWEHRWALSVLNTALG
TH_1284|M.thermoresistible__bu RKGASRVPGRPGLRLISRDGEQTHVSLGVRTPGRHWEHRWALSVLNNALG
Mb2805c|M.bovis_AF2122/97 RKGTGRVNGSPRLTLVSRDAEQTHVSLGIRTPGRGWEHRWALSVLHTALG
Rv2782c|M.tuberculosis_H37Rv RKGTGRVNGSPRLTLVSRDAEQTHVSLGIRTPGRGWEHRWALSVLHTALG
MMAR_1926|M.marinum_M RKGTGRVNGTPQLVLADREAEQTHVSLGVRTPGRGWEHRWALSVLHTALG
MLBr_00855|M.leprae_Br4923 RKSTGRINGGPALTLGKRDAEQTHVLLGVRTPGRSWEHRWALSVLHTALG
MAV_3675|M.avium_104 RKGAGRVNGRPGLLLGTRDAEQTHVSLGVRTPGRGWQHRWALSVLHTALG
MAB_3105c|M.abscessus_ATCC_199 RKGSGRVAAKPGLELVSRDGEQVHLSLGVRTPGRGWQHRWALSVLNSALG
**.:.*: . * * : *:.**.*: **:***** *:********:.***
Mflv_4022|M.gilvum_PYR-GCK GGLSSRLFQQIRETRGLAYSVYSTVDTFADTGALSIYAGCQPERFDEVVR
Mvan_2351|M.vanbaalenii_PYR-1 GGLSSRLFQQIRETRGLAYSVYSTVDTFAESGALSIYAGCLPERFDEVVR
MSMEG_2657|M.smegmatis_MC2_155 GGLSSRLFQEIRETRGLAYSVYSTVDTFSDSGALSIYAGCLPERFEEVVR
TH_1284|M.thermoresistible__bu GGLSSRLFQEIREQRGLAYSVYSTVDMFADSGALSVYAACQPERFDEVVR
Mb2805c|M.bovis_AF2122/97 GGLSSRLFQEVRETRGLAYSVYSALDLFADSGALSVYAACLPERFADVMR
Rv2782c|M.tuberculosis_H37Rv GGLSSRLFQEVRETRGLAYSVYSALDLFADSGALSVYAACLPERFADVMR
MMAR_1926|M.marinum_M GGLSSRLFQEIRESRGLAYSVYSALDIFADSGALSVYAACLPERFAEVMR
MLBr_00855|M.leprae_Br4923 GGLSSRLFQEIRETRGLAYSVYSALDIFADSGALSVYAACLPGRFADVMQ
MAV_3675|M.avium_104 GGLSSRLFQEIRELRGLAYSVYSTVDIFADSGALSVYAACQPERFAEVMA
MAB_3105c|M.abscessus_ATCC_199 GGLSSRLFQEIREQRGLVYAVYSTVDTFSDTGALSVYAGCSPERFDEVTK
*********::** ***.*:***::* *:::****:**.* * ** :*
Mflv_4022|M.gilvum_PYR-GCK VTTDILADVARDGITADECRIAKGSLRGGLVLGLEDSGSRMNRIGRSELN
Mvan_2351|M.vanbaalenii_PYR-1 VTTDVLTEVARDGITADECRIAKGSLRGGLVLGLEDSASRMNRIGRSELN
MSMEG_2657|M.smegmatis_MC2_155 VTTDVLETVARDGISENECRIAKGSLRGGLVLGLEDSASRMHRIGRAELN
TH_1284|M.thermoresistible__bu VTTDVLHRVARDGITEDECRIAKGSLRGGLVLGLEDSASRMHRIGRNELN
Mb2805c|M.bovis_AF2122/97 VTADVLESVARDGITEAECGIAKGSLRGGLVLGLEDSSSRMSRLGRSELN
Rv2782c|M.tuberculosis_H37Rv VTADVLESVARDGITEAECGIAKGSLRGGLVLGLEDSSSRMSRLGRSELN
MMAR_1926|M.marinum_M VTREVLEAVARDGITESECRIAKGSLRGGLVLGLEDSSSRMSRIGRSELN
MLBr_00855|M.leprae_Br4923 VISEVLASVAGDGITEAECRIAKGSLRGGIILGLEDSNSWMSRLGRSELN
MAV_3675|M.avium_104 VTGGVLESVARDGITESECRIAKGSLRGGLVLGLEDSGSRMSRLGRNELN
MAB_3105c|M.abscessus_ATCC_199 VTSQVLGSVVEDGFTPAEIDRAKGALSGGLVLGLEDSASRMNRLGRSELN
* :* *. **:: * ***:* **::****** * * *:** ***
Mflv_4022|M.gilvum_PYR-GCK FGEHRTIADTLSKIDEVTIDEVNAVARQLLTRPFGAAVLGPVRSKRSLPK
Mvan_2351|M.vanbaalenii_PYR-1 YGKHRSIAETLARIDEVTLEDVNAVARQLLTKPFGAAVLGPVHRKRSLPR
MSMEG_2657|M.smegmatis_MC2_155 YGEHRSIEQTLAQIDAVTLDEVNAVARQLLTRDYGAAVLGPDTAKVALPQ
TH_1284|M.thermoresistible__bu YGVHQSIDETLARIDAVTAEEVNMVARRLLNRPFGAAVLGPHRSEKSLPQ
Mb2805c|M.bovis_AF2122/97 YGKHRSIEHTLRQIEQVTVEEVNAVARHLLSRRYGAAVLGPHGSKRSLPQ
Rv2782c|M.tuberculosis_H37Rv YGKHRSIEHTLRQIEQVTVEEVNAVARHLLSRRYGAAVLGPHGSKRSLPQ
MMAR_1926|M.marinum_M YGKHRTIEHTLQQIDRVTVDEVNALARRLLVKRYGAAVLGPYTSKRQLPQ
MLBr_00855|M.leprae_Br4923 YGKYRGIEHTLQQIDEVTVEQVNALAHQLLNKRYGAAVLGPYASKKTLPR
MAV_3675|M.avium_104 YGRHRSIEHTLAQIDRVSVDEVNAIARRLLTQRYGAAVLGPYSTKRSLPQ
MAB_3105c|M.abscessus_ATCC_199 NGKHRTISATLDRIDAVTADEVNAIARQLLGGPAGAAVVGPYRSKRTLPR
* :: * ** :*: *: ::** :*::** ****:** : **:
Mflv_4022|M.gilvum_PYR-GCK PLQQIAG---
Mvan_2351|M.vanbaalenii_PYR-1 PLQRIGS---
MSMEG_2657|M.smegmatis_MC2_155 RLQDIAS---
TH_1284|M.thermoresistible__bu PLWAIAG---
Mb2805c|M.bovis_AF2122/97 QLRAMVG---
Rv2782c|M.tuberculosis_H37Rv QLRAMVG---
MMAR_1926|M.marinum_M QLRAMVN---
MLBr_00855|M.leprae_Br4923 QLRIMVN---
MAV_3675|M.avium_104 QLRAMVR---
MAB_3105c|M.abscessus_ATCC_199 TLRTMIESTS
* :