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LRPERGTLVPRRTDLNHVLVIGSGPIVIGQACEFDYAGTQACRVLRAEGLQVSLVNSNPATIMTDPEFAD HTYVEPITPAFVERVIVQQAERGNRIDALLATLGGQTALNTAVALYENGVLERYGVELIGADFEAIQRGE DRQRFKDLVAKVGGESARSKVCFTMDEVRETVEDLGLPVVVRPSFTMGGLGSGMAHSDEEVGRMAGAGLV ASPSANVLIEESVYGWKEFELELMRDGHDSVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDWEYQRMRDL GIAILREVGVDTGGCNIQFAINPHDGRLIVIEMNPRVSRSSALASKATGFPIAKIAVKLAVGYTLDEILN DITKETPACFEPALDYVVVKAPRFAFEKFPGADPTLTTTMKSVGEAMSLGRNFVEALGKVMRSLETGRFG FWTAPDPQGDVDQVLLRLKTPTEGRLYDVELALRLGASTEKVAQVSGIDPWFVAQIGELVKLRDELVAAP VLDAELLRRAKHNGLSDRQITALRPELLGEDGVRSLRKRLGIHPVYKTVDTCAAEFEAKTPYHYSSYELD PAAETEVVPQTEKPKVLILGSGPNRIGQGIEFDYSCVHAAITLSHNGFETVMVNCNPETVSTDYDTADRL YFEPLTFEDVLEVFYAEEQSAAGGAGVAGVIVQLGGQTPLGLAQRLADAGVPIVGTSPEAIDLAEDRGAF GDVLTAAGLPAPKYGTATTFAQARRIAAEIGYPVLVRPSYVLGGRGMEIVYDEETLKDYITRATALSHEH PVLVDRFLEDAVEIDVDALCDGTEVYIGGVMEHIEEAGIHSGDSACALPPVTLGRSDLEKVRQATEAIAR GIGVVGLLNVQYALKEDVLYVLEANPRASRTVPFVSKATAIPLAKACARIMLGSSISQLRFEGMLAASGD GGNVASHAPIAVKEAVLPFNRLRRADGAAIDSLLGPEMKSTGEVMGIDHDFGRAFAKSQTAAYGSLPTQG TVFVSVANRDKRLLVFPVKRLADLGFHVIATEGTAEMLRRKGIPCDEVRKHFEPPKAGRPALSAVDAIRA GDVDMVINTPYGNSGPRIDGYEIRSAAVSVNIPCVTTVQGASAAVQGIEAGIRGDIGVRSLQELHSAIGA GIAADNEVQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00536 | carB | - | 100% (1129) | carbamoyl phosphate synthase large subunit |
| M. leprae Br4923 | MLBr_00726 | bccA | 1e-07 | 23.08% (286) | acetyl/propionyl CoA carboxylase alpha subunit |
| M. leprae Br4923 | MLBr_02235 | purD | 4e-06 | 23.28% (305) | phosphoribosylamine--glycine ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1419 | carB | 0.0 | 89.02% (1111) | carbamoyl phosphate synthase large subunit |
| M. gilvum PYR-GCK | Mflv_3743 | carB | 0.0 | 84.86% (1110) | carbamoyl phosphate synthase large subunit |
| M. tuberculosis H37Rv | Rv1384 | carB | 0.0 | 88.93% (1111) | carbamoyl phosphate synthase large subunit |
| M. abscessus ATCC 19977 | MAB_2827c | carB | 0.0 | 83.80% (1111) | carbamoyl phosphate synthase large subunit |
| M. marinum M | MMAR_2199 | carB | 0.0 | 89.21% (1121) | carbamoyl-phosphate synthase large chain CarB |
| M. avium 104 | MAV_3389 | carB | 0.0 | 90.02% (1112) | carbamoyl phosphate synthase large subunit |
| M. smegmatis MC2 155 | MSMEG_3047 | carB | 0.0 | 86.33% (1112) | carbamoyl phosphate synthase large subunit |
| M. thermoresistible (build 8) | TH_0818 | - | 0.0 | 85.84% (1116) | PROBABLE CARBAMOYL-PHOSPHATE SYNTHASE LARGE CHAIN CARB |
| M. ulcerans Agy99 | MUL_1784 | carB | 0.0 | 89.08% (1117) | carbamoyl phosphate synthase large subunit |
| M. vanbaalenii PYR-1 | Mvan_2664 | carB | 0.0 | 85.79% (1112) | carbamoyl phosphate synthase large subunit |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3743|M.gilvum_PYR-GCK ------------------------MPRRSDLNHVLVIGSGPILIGQAAEF
Mvan_2664|M.vanbaalenii_PYR-1 ------------------------MPRRPDLNHVLVIGSGPILIGQAAEF
MSMEG_3047|M.smegmatis_MC2_155 ------------------------MPRRSDLNHVLVIGSGPIVIGQACEF
Mb1419|M.bovis_AF2122/97 ------------------------MPRRTDLHHVLVIGSGPIVIGQACEF
Rv1384|M.tuberculosis_H37Rv ------------------------MPRRTDLHHVLVIGSGPIVIGQACEF
MLBr_00536|M.leprae_Br4923 ----------------MRPERGTLVPRRTDLNHVLVIGSGPIVIGQACEF
MAV_3389|M.avium_104 ------------------------MPRRTDLNHVLVIGSGPIVIGQACEF
MMAR_2199|M.marinum_M MPPADTLGSAQDRAPSRPNLRGLLVPRRTDLHHILVIGSGPIVIGQACEF
MUL_1784|M.ulcerans_Agy99 ------------------------MPRRTDLHHILVIGSGPIVIGQACEF
TH_0818|M.thermoresistible__bu ------------------------MPRRTDINHVLVIGSGPIVIGQAAEF
MAB_2827c|M.abscessus_ATCC_199 ------------------------MPRRTDLNHILVIGSGPIVIGQACEF
:***.*::*:********:****.**
Mflv_3743|M.gilvum_PYR-GCK DYSGTQACRVLRAEGLQVTLINSNPATIMTDPEYADHTYVEPITADFVEK
Mvan_2664|M.vanbaalenii_PYR-1 DYSGTQACRVLRAEGLQVTLINSNPATIMTDPEYADHTYVEPITAEFVEK
MSMEG_3047|M.smegmatis_MC2_155 DYSGTQACRVLRSEGIQVSLVNSNPATIMTDPEYADNTYVEPITAAFVEK
Mb1419|M.bovis_AF2122/97 DYSGTQACRVLRAEGLQVSLVNSNPATIMTDPEFADHTYVEPITPAFVER
Rv1384|M.tuberculosis_H37Rv DYSGTQACRVLRAEGLQVSLVNSNPATIMTDPEFADHTYVEPITPAFVER
MLBr_00536|M.leprae_Br4923 DYAGTQACRVLRAEGLQVSLVNSNPATIMTDPEFADHTYVEPITPAFVER
MAV_3389|M.avium_104 DYSGTQACRVLKAEGLQVSLVNSNPATIMTDPEYADHTYVEPITPAFVER
MMAR_2199|M.marinum_M DYSGTQACRVLRAEGLQVSLVNSNPATIMTDPEYADFTYVEPITPEFVER
MUL_1784|M.ulcerans_Agy99 DYSGTQACRVLRAEGLQVSLVNSNPATIMTDPEYADFTYVEPITPEFVER
TH_0818|M.thermoresistible__bu DYSGTQACRVLRAEGLQVSLINSNPATIMTDPEYADHTYVEPITPDFVER
MAB_2827c|M.abscessus_ATCC_199 DYSGTQACRVLRSEGLQVSLVNSNPATIMTDPEYADNTYVEPITAEFVEK
**:********::**:**:*:************:** *******. ***:
Mflv_3743|M.gilvum_PYR-GCK VIAQQAERGNKIDALLPTLGGQTALNTAVKLYENGALERYDVELIGANFD
Mvan_2664|M.vanbaalenii_PYR-1 VIAQQAERGNKIDALLATLGGQTALNTAVKLSENGALERYGVELIGADFE
MSMEG_3047|M.smegmatis_MC2_155 VIAQQAARGNKIDALLATLGGQTALNTAVALHENGVLERYGVELIGADFE
Mb1419|M.bovis_AF2122/97 VIAQQAERGNKIDALLATLGGQTALNTAVALYESGVLEKYGVELIGADFD
Rv1384|M.tuberculosis_H37Rv VIAQQAERGNKIDALLATLGGQTALNTAVALYESGVLEKYGVELIGADFD
MLBr_00536|M.leprae_Br4923 VIVQQAERGNRIDALLATLGGQTALNTAVALYENGVLERYGVELIGADFE
MAV_3389|M.avium_104 VIAQQAERGNKIDALLATLGGQTALNTAVALYENGALDRYGVELIGADFD
MMAR_2199|M.marinum_M VIAQQAERGNKIDAVLATLGGQTALNTAVALHENGALERYGVELIGADFE
MUL_1784|M.ulcerans_Agy99 VIAQQAERGNKIDAVLATLGGQTALNTAVALHENGALERYGVELIGADFE
TH_0818|M.thermoresistible__bu VIIQQAERGNKIDALLATLGGQTALNTAVALHENGALQRHGVELIGADID
MAB_2827c|M.abscessus_ATCC_199 VIAAQAEKGNKIDALLPTLGGQTALNTAVALYENGALDRYGVELIGANFE
** ** :**:***:*.************ * *.*.*:::.******:::
Mflv_3743|M.gilvum_PYR-GCK AIQRGEDRQKFKDIVTKVGGESAKSRVCFTMDEVRDTVAELGLPVVVRPS
Mvan_2664|M.vanbaalenii_PYR-1 AIQRGEDRQKFKDIVTKVGGESARSRVCFTMDEVRDTVADLGLPVVVRPS
MSMEG_3047|M.smegmatis_MC2_155 AIQRGEDRQKFKDIVAKVGGESARSRVCFTMDEVRETVAELGLPVVVRPS
Mb1419|M.bovis_AF2122/97 AIQRGEDRQRFKDIVAKAGGESARSRVCFTMAEVRETVAELGLPVVVRPS
Rv1384|M.tuberculosis_H37Rv AIQRGEDRQRFKDIVAKAGGESARSRVCFTMAEVRETVAELGLPVVVRPS
MLBr_00536|M.leprae_Br4923 AIQRGEDRQRFKDLVAKVGGESARSKVCFTMDEVRETVEDLGLPVVVRPS
MAV_3389|M.avium_104 AIQRGEDRQRFKDIVAKVGGESARSRVCFTMDEVRETVAELGLPVVVRPS
MMAR_2199|M.marinum_M AIQRGEDRQRFKDIVAKVGGESARSRVCFTMDEVRETVAELGLPVVVRPS
MUL_1784|M.ulcerans_Agy99 AIQRGEDRQRFKDIVAKFGGESARSRVCFTMDEVRETVAELGLPVVVRPS
TH_0818|M.thermoresistible__bu AIQRGEDRQRFKDIVAKVGGESARSRVCYTMDEVRETVAELGLPVVVRPS
MAB_2827c|M.abscessus_ATCC_199 AIQRGEDRQRFKDIVAKVGGESAKSRVCFTMEEVRETVADLGLPVVVRPS
*********:***:*:* *****:*:**:** ***:** :**********
Mflv_3743|M.gilvum_PYR-GCK FTMGGLGSGMAYSADDVERMAGEGLAASPSANVLIEESIYGWKEYELELM
Mvan_2664|M.vanbaalenii_PYR-1 FTMGGLGSGMAYSAEDVERMAGDGLAASPSANVLIEESIYGWKEYELELM
MSMEG_3047|M.smegmatis_MC2_155 FTMGGLGSGMAYSAEDVERMAGDGLAASPSANVLIEESIYGWKEYELELM
Mb1419|M.bovis_AF2122/97 FTMGGLGSGIAYSTDEVDRMAGAGLAASPSANVLIEESIYGWKEFELELM
Rv1384|M.tuberculosis_H37Rv FTMGGLGSGIAYSTDEVDRMAGAGLAASPSANVLIEESIYGWKEFELELM
MLBr_00536|M.leprae_Br4923 FTMGGLGSGMAHSDEEVGRMAGAGLVASPSANVLIEESVYGWKEFELELM
MAV_3389|M.avium_104 FTMGGLGSGMARSVEEVDRMAGAGLAESPSANVLIEESIYGWKEFELELM
MMAR_2199|M.marinum_M FTMGGLGSGMAYSADEVDRMAGAGLAASPSANVLIEESIYGWKEFELELM
MUL_1784|M.ulcerans_Agy99 FTMGGLGSGMAYSADEVDRMAGAGLAASPSANVLIEESIYGWKEFELELM
TH_0818|M.thermoresistible__bu FTMGGLGSGIAHSVEDVDRMAGDGLAASPSANVLIEESIVGWKEYELELM
MAB_2827c|M.abscessus_ATCC_199 FTMGGLGSGMAYTADDVERMAGEGLSASPSANVLIEESIYGWKEFELELM
*********:* : ::* **** ** ***********: ****:*****
Mflv_3743|M.gilvum_PYR-GCK RDGRDNVVVVCSIENFDPMGVHTGDSVTVAPAMTLTDREYQKMRTLGIEI
Mvan_2664|M.vanbaalenii_PYR-1 RDGHDNVVVVCSIENFDPMGVHTGDSVTVAPAMTLTDREYQTMRTLGIEI
MSMEG_3047|M.smegmatis_MC2_155 RDGRDNVVVVCSIENFDPMGVHTGDSVTVAPAMTLTDREYQKMRDLGIAI
Mb1419|M.bovis_AF2122/97 RDGHDNVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDREYQRMRDLGIAI
Rv1384|M.tuberculosis_H37Rv RDGHDNVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDREYQRMRDLGIAI
MLBr_00536|M.leprae_Br4923 RDGHDSVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDWEYQRMRDLGIAI
MAV_3389|M.avium_104 RDGNDNVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDREYQRMRDLGIAI
MMAR_2199|M.marinum_M RDGHDNVVVVCSIENLDPMGVHTGDSVTVAPAMTLTDREYQRLRDLGIAI
MUL_1784|M.ulcerans_Agy99 RDGHDNVVVVCSIENLDPMGVHTGDSVTVAPAMTLTDREYQRLRDLGIAI
TH_0818|M.thermoresistible__bu RDGNDNVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDREYQRMRDLGIAI
MAB_2827c|M.abscessus_ATCC_199 RDGRDNVVVVCSIENVDPMGVHTGDSVTVAPAMTLTDREYQKMRDLGIAI
***.*.*********.********************* *** :* *** *
Mflv_3743|M.gilvum_PYR-GCK LREVGVDTGGCNIQFAVNPKDGRLIVIEMNPRVSRSSALASKATGFPIAK
Mvan_2664|M.vanbaalenii_PYR-1 LREVGVDTGGCNIQFAVNPKDGRLIVIEMNPRVSRSSALASKATGFPIAK
MSMEG_3047|M.smegmatis_MC2_155 LREVGVDTGGCNIQFAVNPRDGRLIVIEMNPRVSRSSALASKATGFPIAK
Mb1419|M.bovis_AF2122/97 LREVGVDTGGCNIQFAVNPRDGRLIVIEMNPRVSRSSALASKATGFPIAK
Rv1384|M.tuberculosis_H37Rv LREVGVDTGGCNIQFAVNPRDGRLIVIEMNPRVSRSSALASKATGFPIAK
MLBr_00536|M.leprae_Br4923 LREVGVDTGGCNIQFAINPHDGRLIVIEMNPRVSRSSALASKATGFPIAK
MAV_3389|M.avium_104 LREVGVDTGGCNIQFAVNPKDGRLIVIEMNPRVSRSSALASKATGFPIAK
MMAR_2199|M.marinum_M LREVGVDTGGCNIQFAVNPRDGRLIVIEMNPRVSRSSALASKATGFPIAK
MUL_1784|M.ulcerans_Agy99 LREVGVDTGGCNIQFAVNPRDGRLIVIEMNPRVSRSSALASKATGFPIAK
TH_0818|M.thermoresistible__bu LREVGVATGGCNIQFAVNPKTGRLIVIEMNPRVSRSSALASKATGFPIAK
MAB_2827c|M.abscessus_ATCC_199 LREVGVDTGGCNIQFAINPRDGRLIVIEMNPRVSRSSALASKATGFPIAK
****** *********:**: *****************************
Mflv_3743|M.gilvum_PYR-GCK IAAKLAIGYTLDEIVNDITKETPACFEPTLDYVVVKAPRFAFEKFPGADA
Mvan_2664|M.vanbaalenii_PYR-1 IAAKLAIGYTLDEIVNDITKETPACFEPTLDYVVVKAPRFAFEKFPGADG
MSMEG_3047|M.smegmatis_MC2_155 IAAKLAIGYTLDEILNDITKETPACFEPTLDYVVVKAPRFAFEKFPGADA
Mb1419|M.bovis_AF2122/97 IAAKLAIGYTLDEIVNDITGETPACFEPTLDYVVVKAPRFAFEKFPGADP
Rv1384|M.tuberculosis_H37Rv IAAKLAIGYTLDEIVNDITGETPACFEPTLDYVVVKAPRFAFEKFPGADP
MLBr_00536|M.leprae_Br4923 IAVKLAVGYTLDEILNDITKETPACFEPALDYVVVKAPRFAFEKFPGADP
MAV_3389|M.avium_104 IAAKLAIGYTLDEIVNDITKETPACFEPTLDYVVVKAPRFAFEKFPGADP
MMAR_2199|M.marinum_M IAAKLAIGYTLDEIVNDITKETPACFEPTLDYVVVKAPRFAFEKFPGADA
MUL_1784|M.ulcerans_Agy99 IAAKLAIGYTLDEIVNDITKETPACFEPTLDYVVVKAPRFAFEKFPGADA
TH_0818|M.thermoresistible__bu IAAKLAIGYTLDEIVNDITGETPACFEPTLDYVVVKAPRFAFEKFPGADP
MAB_2827c|M.abscessus_ATCC_199 IAAKLAIGYTLDEIVNDITKETPACFEPTLDYVVVKAPRFAFEKFPGADA
**.***:*******:**** ********:********************
Mflv_3743|M.gilvum_PYR-GCK TLTTTMKSVGEAMSLGRNFIEALGKVMRSLETGRAGFWTG-EDPVGELGE
Mvan_2664|M.vanbaalenii_PYR-1 TLTTTMKSVGEAMSLGRNFIEALGKVMRSLETGRAGFWTG-PDPEGSVDE
MSMEG_3047|M.smegmatis_MC2_155 TLTTTMKSVGEAMSLGRNFIEALGKVMRSLETTRAGFWTA-PDPDTTVEQ
Mb1419|M.bovis_AF2122/97 TLTTTMKSVGEAMSLGRNFVEALGKVMRSLETTRAGFWTA-PDPDGGIEE
Rv1384|M.tuberculosis_H37Rv TLTTTMKSVGEAMSLGRNFVEALGKVMRSLETTRAGFWTA-PDPDGGIEE
MLBr_00536|M.leprae_Br4923 TLTTTMKSVGEAMSLGRNFVEALGKVMRSLETGRFGFWTA-PDPQGDVDQ
MAV_3389|M.avium_104 TLTTTMKSVGEAMSLGRNFIEALGKVMRSLETSRAGFWTK-PDPDGGLDD
MMAR_2199|M.marinum_M TLTTTMKSVGEAMSLGRNFVEALGKVMRSLETSRAGFWTA-TDPEGGLDD
MUL_1784|M.ulcerans_Agy99 TLTTTMKSVGEAMSLGRNFVKALGKVMRSLETSRAGFWTA-TDPEGGLDD
TH_0818|M.thermoresistible__bu LLTTTMKSVGEAMSLGRNFIEALGKVMRSVETKRAGFWTA-PDDDVTLDE
MAB_2827c|M.abscessus_ATCC_199 TLTTTMKSVGEAMSLGRNFAEALGKVMRSLETSAAGFWTDKAEPIEDLDA
****************** :********:** **** : :
Mflv_3743|M.gilvum_PYR-GCK VLARLRTPTDGRLYDIEYALRIGATVEEVAEASGVDPWFVDQIGGLVELR
Mvan_2664|M.vanbaalenii_PYR-1 VLTRLHTATDGRLYDIEYALRLGATVEQVAVASGVDPWFVEQIGRLVALR
MSMEG_3047|M.smegmatis_MC2_155 LLTNLRTAQDGRIYDMELALRLGASVEQVSEASGVDPWFVEQIAGLVDLR
Mb1419|M.bovis_AF2122/97 ALTRLRTPAEGRLYDIELALRLGATVERVAEASGVDPWFIAQINELVNLR
Rv1384|M.tuberculosis_H37Rv ALTRLRTPAEGRLYDIELALRLGATVERVAEASGVDPWFIAQINELVNLR
MLBr_00536|M.leprae_Br4923 VLLRLKTPTEGRLYDVELALRLGASTEKVAQVSGIDPWFVAQIGELVKLR
MAV_3389|M.avium_104 VLARLQTPTEGRLYDLELALRLGAPVERVAQASGVDPWFIAQIGELVALR
MMAR_2199|M.marinum_M VLTRLQTPTEGRLYDLELALRLGASVDRVAEASGVDPWFVAQIDELVGLR
MUL_1784|M.ulcerans_Agy99 VLTRLQTPTEGRLYDLELALRLGASVDRVAEASGVDPWFVAQIDELVGLR
TH_0818|M.thermoresistible__bu LLERLKVPTDGRLYDIEHALRLGGTVEQVAQASGVDPWFVAQIEELVRLR
MAB_2827c|M.abscessus_ATCC_199 FLKELRVPRDGRLYGIERALAAGVPVEQVAEVTGVDPWFVEEIAQINQLG
* .*:.. :**:*.:* ** * ..:.*: .:*:****: :* : *
Mflv_3743|M.gilvum_PYR-GCK AELTDAPVLGEELLRRSKHHGLSDRQIAALRPELAGEMGVRALRQRLGIH
Mvan_2664|M.vanbaalenii_PYR-1 AELIDAPVLGEELLRRSKHNGLSDRQIAALRPELAGEMGVRVLRQRLGIH
MSMEG_3047|M.smegmatis_MC2_155 AELVEAPVLDADLLRRAKYSGLSDRQISALRPELAGEAGVRALRQRLGIH
Mb1419|M.bovis_AF2122/97 NELVAAPVLNAELLRRAKHSGLSDHQIASLRPELAGEAGVRSLRVRLGIH
Rv1384|M.tuberculosis_H37Rv NELVAAPVLNAELLRRAKHSGLSDHQIASLRPELAGEAGVRSLRVRLGIH
MLBr_00536|M.leprae_Br4923 DELVAAPVLDAELLRRAKHNGLSDRQITALRPELLGEDGVRSLRKRLGIH
MAV_3389|M.avium_104 GELIGAPVLDADLLRRAKHHGLSDRQIAALRPELAGENGVRSLRERLGVH
MMAR_2199|M.marinum_M AELVDAPVLDADLLRHAKHSGLSDRQIASLRPELAGEDGVRSLRERLGIH
MUL_1784|M.ulcerans_Agy99 AELVDAPVLDADLLRHAKHSGLSDRQIASLRPELAGEDGVRSLRERLGIH
TH_0818|M.thermoresistible__bu SELVDAPVLNADLLRRAKHCGLSDRQIAALRPELAGELGVRALRQRLGIH
MAB_2827c|M.abscessus_ATCC_199 TELREAPILDEELLRRAKHYGLSDRQIAALRPELAGENGVRSLRHRMGIR
** **:*. :***::*: ****:**::***** ** *** ** *:*::
Mflv_3743|M.gilvum_PYR-GCK PVFKTVDTCAAEFEAKTPYHYSSYEMDPAAETEVAPQTERGKVLILGSGP
Mvan_2664|M.vanbaalenii_PYR-1 PVFKTVDTCAAEFEARTPYHYSSYELDPSAETEVAPQAERPKVLILGSGP
MSMEG_3047|M.smegmatis_MC2_155 PVFKTVDTCAAEFDAKTPYHYSSYELDPAAETEVAPQTEKPKVLILGSGP
Mb1419|M.bovis_AF2122/97 PVYKTVDTCAAEFEAQTPYHYSSYELDPAAETEVAPQTERPKVLILGSGP
Rv1384|M.tuberculosis_H37Rv PVYKTVDTCAAEFEAQTPYHYSSYELDPAAETEVAPQTERPKVLILGSGP
MLBr_00536|M.leprae_Br4923 PVYKTVDTCAAEFEAKTPYHYSSYELDPAAETEVVPQTEKPKVLILGSGP
MAV_3389|M.avium_104 PVYKTVDTCAAEFEAKTPYHYSSYELDPAAETEVAPQPQRPKVLILGSGP
MMAR_2199|M.marinum_M PVYKTVDTCAAEFEAKTPYHYSSYELDPAAETEVAPQIDKPKVLILGSGP
MUL_1784|M.ulcerans_Agy99 PVYKTVDTCAAEFEAKTPYHYSSYELDPAAETEVAPQIDKPKVLILGSGP
TH_0818|M.thermoresistible__bu PVFKTVDTCAAEFEAKTPYHYSSYELDPAAETEVAPQTERPKVLILGSGP
MAB_2827c|M.abscessus_ATCC_199 PVYKTVDTCAAEFEAKTPYHYSSYELDPAAESEVAPQTERPKVLILGSGP
**:**********:*:*********:**:**:**.** :: *********
Mflv_3743|M.gilvum_PYR-GCK NRIGQGIEFDYSCVHAATTLSEAGFETVMINCNPETVSTDYDTADRLYFE
Mvan_2664|M.vanbaalenii_PYR-1 NRIGQGIEFDYSCVHAATTLTEAGFETVMINCNPETVSTDYDTADRLYFE
MSMEG_3047|M.smegmatis_MC2_155 NRIGQGIEFDYSCVHAATTLSDAGFETVMVNCNPETVSTDYDTADRLYFE
Mb1419|M.bovis_AF2122/97 NRIGQGIEFDYSCVHAATTLSQAGFETVMVNCNPETVSTDYDTADRLYFE
Rv1384|M.tuberculosis_H37Rv NRIGQGIEFDYSCVHAATTLSQAGFETVMVNCNPETVSTDYDTADRLYFE
MLBr_00536|M.leprae_Br4923 NRIGQGIEFDYSCVHAAITLSHNGFETVMVNCNPETVSTDYDTADRLYFE
MAV_3389|M.avium_104 NRIGQGIEFDYSCVHAATTLSQAGFETVMVNCNPETVSTDYDTADRLYFE
MMAR_2199|M.marinum_M NRIGQGIEFDYSCVHAATTLSQAGFETVMINCNPETVSTDYDTADRLYFE
MUL_1784|M.ulcerans_Agy99 NRIGQGIEFDYSCVHAATTLSQAGFETVMINCNPETVSTDYDTADRLYFE
TH_0818|M.thermoresistible__bu NRIGQGIEFDYSCVHAATTLSEAGFETVMINCNPETVSTDYDTADRLYFE
MAB_2827c|M.abscessus_ATCC_199 NRIGQGIEFDYSCVHAATTLSQAGFETIMVNCNPETVSTDYDTADRLYFE
***************** **:. ****:*:********************
Mflv_3743|M.gilvum_PYR-GCK PLTFEDVLEIYYAEQRSGEG----GPGVIGVIVQLGGQTPLGLAERLEKA
Mvan_2664|M.vanbaalenii_PYR-1 PLTFEDVLEIYYAEQASGEG----GPGVVGVIVQLGGQTPLGLAERLEKA
MSMEG_3047|M.smegmatis_MC2_155 PLTFEDVLEIYHAESLSGEG----GPGVVGVIVQLGGQTPLGLAKRLEDA
Mb1419|M.bovis_AF2122/97 PLTFEDVLEVYHAEMESGSG----GPGVAGVIVQLGGQTPLGLAHRLADA
Rv1384|M.tuberculosis_H37Rv PLTFEDVLEVYHAEMESGSG----GPGVAGVIVQLGGQTPLGLAHRLADA
MLBr_00536|M.leprae_Br4923 PLTFEDVLEVFYAEEQSAAG----GAGVAGVIVQLGGQTPLGLAQRLADA
MAV_3389|M.avium_104 PLTFEDVLEVFRAEQQSGAG----GPGVVGVIVQLGGQTPLGLAQRLADA
MMAR_2199|M.marinum_M PLTFEDVLEVFHAEEQSAAG----GAGVVGVIVQLGGQTPLGLAERLANA
MUL_1784|M.ulcerans_Agy99 PLTFEDVLEVFHAEEQSAAG----GAGVVGVIVQLGGQTPLGLAERLANA
TH_0818|M.thermoresistible__bu PLTFEDVLEVYYAEDASGRGPDGTGPGVVGVIVQLGGQTPLGLAQRLADA
MAB_2827c|M.abscessus_ATCC_199 PLTFEDVLEVYHAESESGRG----GPGVVGVIVQLGGQTPLGLAKRLADA
*********:: ** *. * *.** ***************.** .*
Mflv_3743|M.gilvum_PYR-GCK GVPIVGTKPEAIDLAEDRGEFGEVLRRAGLPAPRFGMATSFDQARRIAAE
Mvan_2664|M.vanbaalenii_PYR-1 GVPIVGTLPEAIDLAEDRGEFGEVLRRAGLPAPRFGMATSFDQARRIAAE
MSMEG_3047|M.smegmatis_MC2_155 GVPIVGTSPKAIDLAEDRGHFGEVLTAAGLPAPKYGMATSFDQARRIAAD
Mb1419|M.bovis_AF2122/97 GVPIVGTPPEAIDLAEDRGAFGDLLSAAGLPAPKYGTATTFAQARRIAEE
Rv1384|M.tuberculosis_H37Rv GVPIVGTPPEAIDLAEDRGAFGDLLSAAGLPAPKYGTATTFAQARRIAEE
MLBr_00536|M.leprae_Br4923 GVPIVGTSPEAIDLAEDRGAFGDVLTAAGLPAPKYGTATTFAQARRIAAE
MAV_3389|M.avium_104 GVPIVGTPPEAIDLAEDRGSFGDVLTAAGLPAPKYGTATTFAQARRIAVD
MMAR_2199|M.marinum_M GVPIVGTPPAAIDLAEDRGAFGDVLTAAGLPAPRYGTATTFAQARRIAED
MUL_1784|M.ulcerans_Agy99 GVPIVGTPPAAIDLAEDRGAFGDVLTAAGLPAPRYGTATTFAQARRIAED
TH_0818|M.thermoresistible__bu GVPIVGTRPEAIDLAEDRGLFGDVLTRAGLPAPKYGMATSFEQAREIAER
MAB_2827c|M.abscessus_ATCC_199 GVPVVGTSPAAIDRAEDRGVFGDLLVSAGLPAPRFGTATTFEQAKQIAAD
***:*** * *** ***** **::* ******::* **:* **:.**
Mflv_3743|M.gilvum_PYR-GCK IGYPVLVRPSYVLGGRGMEIVYDEDTLEGYITRATQLSPEHPVLVDRFLE
Mvan_2664|M.vanbaalenii_PYR-1 IGYPVLVRPSYVLGGRGMEIVYDEETLEGYITRATELSPEHPVLVDRFLE
MSMEG_3047|M.smegmatis_MC2_155 IGYPVLVRPSYVLGGRGMEIVYDEETLRGYITRATQLSPEHPVLVDRFLE
Mb1419|M.bovis_AF2122/97 IGYPVLVRPSYVLGGRGMEIVYDEETLQGYITRATQLSPEHPVLVDRFLE
Rv1384|M.tuberculosis_H37Rv IGYPVLVRPSYVLGGRGMEIVYDEETLQGYITRATQLSPEHPVLVDRFLE
MLBr_00536|M.leprae_Br4923 IGYPVLVRPSYVLGGRGMEIVYDEETLKDYITRATALSHEHPVLVDRFLE
MAV_3389|M.avium_104 IGYPVLVRPSYVLGGRGMEIVYDEETLRDYITRATELSPEHPVLVDRFLE
MMAR_2199|M.marinum_M IGYPVLVRPSYVLGGRGMEIVYDEETLRGYITRATELSPAHPVLVDRFLE
MUL_1784|M.ulcerans_Agy99 IGYPVLVRPSYVLGGRGMEIVYDEETLRGYITRATELSPAHPVLVDRFLE
TH_0818|M.thermoresistible__bu IGYPVLVRPSYVLGGRGMEIVYDEETLHAYITRATELSPEHPVLVDRFLE
MAB_2827c|M.abscessus_ATCC_199 IGYPVLVRPSYVLGGRGMEIVYDEETLHGYIARATQLSPEHPVLVDRFLE
************************:**. **:*** ** **********
Mflv_3743|M.gilvum_PYR-GCK DAIEIDVDALCDGTEVYIGGVMEHIEEAGIHSGDSACALPPVTLGRSDIE
Mvan_2664|M.vanbaalenii_PYR-1 DAIEIDVDALCDGTEVYIGGVMEHIEEAGIHSGDSACALPPVTLGRSDIE
MSMEG_3047|M.smegmatis_MC2_155 DAIEIDVDALCDGTEVYIGGIMEHIEEAGIHSGDSACALPPVTLGRSDIE
Mb1419|M.bovis_AF2122/97 DAVEIDVDALCDGAEVYIGGIMEHIEEAGIHSGDSACALPPVTLGRSDIE
Rv1384|M.tuberculosis_H37Rv DAVEIDVDALCDGAEVYIGGIMEHIEEAGIHSGDSACALPPVTLGRSDIA
MLBr_00536|M.leprae_Br4923 DAVEIDVDALCDGTEVYIGGVMEHIEEAGIHSGDSACALPPVTLGRSDLE
MAV_3389|M.avium_104 DAVEIDVDALCDGTEVYIGGIMEHIEEAGIHSGDSACALPPVTLGRSDIE
MMAR_2199|M.marinum_M DAVEIDVDALCDGTEVYIGGVMEHIEEAGIHSGDSACALPPVTLGRSDIE
MUL_1784|M.ulcerans_Agy99 DAVEIDVDALCDGTEVYIGGVMEHIEEAGIHSGDSACALPRVTLGRSDIE
TH_0818|M.thermoresistible__bu DAIEIDVDALCDGTEVYIGGVMEHIEEAGIHSGDSACALPPVTLGRSDID
MAB_2827c|M.abscessus_ATCC_199 DAIEIDVDALCDGTEVYLGGVMEHIEEAGIHSGDSACALPPVTLGRSDIE
**:**********:***:**:******************* *******:
Mflv_3743|M.gilvum_PYR-GCK AVRRATEAIAFGVGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKAT
Mvan_2664|M.vanbaalenii_PYR-1 AVRRATEAIAFGIGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKAT
MSMEG_3047|M.smegmatis_MC2_155 AVRRATEAIAHGIGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKAT
Mb1419|M.bovis_AF2122/97 KVRKATEAIAHGIGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKAT
Rv1384|M.tuberculosis_H37Rv KVRKATEAIAHGIGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKAT
MLBr_00536|M.leprae_Br4923 KVRQATEAIARGIGVVGLLNVQYALKEDVLYVLEANPRASRTVPFVSKAT
MAV_3389|M.avium_104 KVRRATEAIAHGIGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKAT
MMAR_2199|M.marinum_M NVRKATEAIAHGIGVVGLLNVQYALKDDILYVLEANPRASRTVPFVSKAT
MUL_1784|M.ulcerans_Agy99 KVRKATEAIAHGIGVVGLLNVQYALKDDILYVLEANPRASRTVPFVSKAT
TH_0818|M.thermoresistible__bu AVRRATEAIAHGIGVVGLLNVQYALKDDKLYVLEANPRASRTVPFVSKAT
MAB_2827c|M.abscessus_ATCC_199 KVRKATEAIAHGIGVVGLLNVQYALKDDVLYVLEANPRASRTVPFVSKAT
**:****** *:*************:* *********************
Mflv_3743|M.gilvum_PYR-GCK AVPLAKACARIMLGASIAELREEGVLARTGDGAATARNAPVAVKEAVLPF
Mvan_2664|M.vanbaalenii_PYR-1 AVPLAKACARIMLGATIAQLREEGVLASTGDGAVTARNAPVAVKEAVLPF
MSMEG_3047|M.smegmatis_MC2_155 AVPLAKACARVMLGATITQLRDEGLLSKAGDGAHVGRSTPVAVKEAVLPF
Mb1419|M.bovis_AF2122/97 AVPLAKACARIMLGATIAQLRAEGLLAVTGDGAHAARNAPIAVKEAVLPF
Rv1384|M.tuberculosis_H37Rv AVPLAKACARIMLGATIAQLRAEGLLAVTGDGAHAARNAPIAVKEAVLPF
MLBr_00536|M.leprae_Br4923 AIPLAKACARIMLGSSISQLRFEGMLAASGDGGNVASHAPIAVKEAVLPF
MAV_3389|M.avium_104 AIPLAKACARIMLGATISQLRAEEMLAASGDGAHAALNAPIAVKEAVLPF
MMAR_2199|M.marinum_M AVPLAKACARVMLGASISQLRAEGMLARTGDGANADPRAPIAVKEAVLPF
MUL_1784|M.ulcerans_Agy99 AVPLAKACARVMLGASISQLRAEGMLARTGDGANADPRAPIAVKEAVLPF
TH_0818|M.thermoresistible__bu AVPLAKACARIMLGATIAELRAEGLLAADGDGATPAPDAPIAVKEAVLPF
MAB_2827c|M.abscessus_ATCC_199 AVPLAKACARIMLGATIAGLREEGLLPAEGDGATSLPGAPVAVKEAVLPF
*:********:***::*: ** * :*. ***. :*:*********
Mflv_3743|M.gilvum_PYR-GCK HRFRKADGAQIDSLLGPEMKSTGEVMGIAHDFGSAFAKSQTAAYGSLPAS
Mvan_2664|M.vanbaalenii_PYR-1 HRFRKADGSQIDSLLGPEMKSTGEVMGIAADFGSAFAKSQTAAYGSLPAQ
MSMEG_3047|M.smegmatis_MC2_155 HRFRRADGAQIDSLLGPEMKSTGEVMGIDHDFGTAFAKSQTAAYGSLPTE
Mb1419|M.bovis_AF2122/97 HRFRRADGAAIDSLLGPEMKSTGEVMGIDRDFGSAFAKSQTAAYGSLPAQ
Rv1384|M.tuberculosis_H37Rv HRFRRADGAAIDSLLGPEMKSTGEVMGIDRDFGSAFAKSQTAAYGSLPAQ
MLBr_00536|M.leprae_Br4923 NRLRRADGAAIDSLLGPEMKSTGEVMGIDHDFGRAFAKSQTAAYGSLPTQ
MAV_3389|M.avium_104 HRFRTVEGAGIDSLLGPEMKSTGEVMGIDRDFGSAFAKSQTAAYGSLPAQ
MMAR_2199|M.marinum_M HRFRRADGAAIDSLLGPEMKSTGEVMGIDRDFGSAFAKSQTAAYGSLPAA
MUL_1784|M.ulcerans_Agy99 HRFRRADGAAIDSLLGPEMKSTGEVMGIDRDFGSAFAKSQTAAYGSLPAA
TH_0818|M.thermoresistible__bu HRFRRADGTGIDNLLGPEMKSTGEVMGIDSDFGSAFAKSQTAAYGSLPVE
MAB_2827c|M.abscessus_ATCC_199 HRFRKADGSGVDSLLGPEMKSTGEVMGIDADFGSAFAKSQTAAYGSLPKE
:*:* .:*: :*.*************** *** **************
Mflv_3743|M.gilvum_PYR-GCK GTVFVSVANRDKRSLVFPVKRLADLGFKILATEGTAEMLRRNGIPCEEVR
Mvan_2664|M.vanbaalenii_PYR-1 GTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCEEVR
MSMEG_3047|M.smegmatis_MC2_155 GTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCDEVR
Mb1419|M.bovis_AF2122/97 GTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCDDVR
Rv1384|M.tuberculosis_H37Rv GTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCDDVR
MLBr_00536|M.leprae_Br4923 GTVFVSVANRDKRLLVFPVKRLADLGFHVIATEGTAEMLRRKGIPCDEVR
MAV_3389|M.avium_104 GTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCDEVR
MMAR_2199|M.marinum_M GTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCDEVR
MUL_1784|M.ulcerans_Agy99 GTVFVSVANRDKRSLVFPVKRLADLGFRVLATEGTAEMLRRNGIPCDEVR
TH_0818|M.thermoresistible__bu GTVFVSVANRDKRSLVFPVKRMADLGFRVLATEGTAEMLRRNGIPCDVVR
MAB_2827c|M.abscessus_ATCC_199 GTIFVSVANRDKRSLVFPVKRLADLGFTVLATEGTAEMLRRNGIPCEEVR
**:********** *******:***** ::***********:****: **
Mflv_3743|M.gilvum_PYR-GCK KHFEEPSADRPLRSAVEAIKAGDVDMVLNTPYGNSGPRIDGYEIRSAAVS
Mvan_2664|M.vanbaalenii_PYR-1 KHFQEFSEGLPQMSAVDAIKAGHVDMVINTPYGNSGPRIDGYEIRSAAVS
MSMEG_3047|M.smegmatis_MC2_155 KHYEDPSAADPRPSAVEVIKAGEVNMVINTPYGNSGPRVDGYEIRSAAVS
Mb1419|M.bovis_AF2122/97 KHFEPAQPGRPTMSAVDAIRAGEVNMVINTPYGNSGPRIDGYEIRSAAVA
Rv1384|M.tuberculosis_H37Rv KHFEPAQPGRPTMSAVDAIRAGEVNMVINTPYGNSGPRIDGYEIRSAAVA
MLBr_00536|M.leprae_Br4923 KHFEPPKAGRPALSAVDAIRAGDVDMVINTPYGNSGPRIDGYEIRSAAVS
MAV_3389|M.avium_104 KHFEDPQPGRPEMSAVDAIKAGEVDMVINTPYGNSGPRIDGYEIRSAAVS
MMAR_2199|M.marinum_M KHFEAPQPGRPAISAVDAIRAGEVDMVINTPYGNSGPRVDGYEIRSVAVS
MUL_1784|M.ulcerans_Agy99 KHFEAPQPGRPAISAVDAIRAGEVDMVINTPYGNSGPRVDGYEIRSVAVS
TH_0818|M.thermoresistible__bu KHFEEPSPDRPAMSAVDAIRAGEVDIVINTPYGNSGPRRDGYEIRAAAVS
MAB_2827c|M.abscessus_ATCC_199 KHYQEPGGTLPALSAVDVIKAGDVAMVINTPYGNSGPRVDGYEIRSAAVS
**:: * ***:.*:**.* :*:********** ******:.**:
Mflv_3743|M.gilvum_PYR-GCK MNIPCVTTVQGASAAVQGIEAGIRGDIGVMSLQELHSTLVS---------
Mvan_2664|M.vanbaalenii_PYR-1 MNIPCVTTVQGASAAVQGIEAGIRGDIGVRSLQELHSALGS---------
MSMEG_3047|M.smegmatis_MC2_155 MNIPCVTTVQGASAAVQGIEAGIRGDIGVMSLQELHSELGSRRS------
Mb1419|M.bovis_AF2122/97 GNIPCITTVQGASAAVQGIEAGIRGDIGVRSLQELHRVIGGVER------
Rv1384|M.tuberculosis_H37Rv GNIPCITTVQGASAAVQGIEAGIRGDIGVRSLQELHRVIGGVER------
MLBr_00536|M.leprae_Br4923 VNIPCVTTVQGASAAVQGIEAGIRGDIGVRSLQELHSAIGAGIAADNEVQ
MAV_3389|M.avium_104 VNIPCVTTVQGASAAVQGIEAGIRGDIGVRSLQELHSQIASDKGPR----
MMAR_2199|M.marinum_M ANIPCVTTVQGASAAVQGIEAGIRGDIGVRSLQELHRAIEQQSAADGGAR
MUL_1784|M.ulcerans_Agy99 VNIPCVTTVQGALAAVQGIEAGIRGDIGVRSLQELHRAIEQQSAADGGAR
TH_0818|M.thermoresistible__bu MNIPCVTTVQGASAAVQGIEAAIRGDIGVRSLQELHRTLGSA--------
MAB_2827c|M.abscessus_ATCC_199 MNIPCITTVQGASAAVQGIEAGIRGDIGVRSLQELHAGLR----------
****:****** ********.******* ****** :