For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VEGPHIETNNAWVEFPIFDAKARSLKKAVLGKAGGTIGRNNSNVVVIEALRDITMSLSVGDRVGLVGHNG AGKSTLLRLLSGIYEPTRGWAKVTGRVAPVFDLGIGMDPEISGYENIIIRGLFLGQTRKQMLGKVDEIAE FTELGDYLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGSVDTDFLKKAQSRLQSLVERSGILVFA SHSNEFLARLCKTAMWIDHGVIELSGGIEDVVRAYEGEDAARHVREVIAETASAQNASGDE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_00114 | - | - | 100% (272) | putative ABC transporter ATP-binding component |
| M. leprae Br4923 | MLBr_02352 | - | 2e-15 | 25.34% (221) | putative antibiotic resistance efflux protein |
| M. leprae Br4923 | MLBr_01089 | - | 6e-12 | 23.50% (200) | putative ABC-transport protein, ATP-binding component |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3810 | rfbE | 1e-138 | 91.39% (267) | o-antigen/lipopolysaccharide transport ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_1186 | - | 1e-127 | 87.94% (257) | ABC transporter related |
| M. tuberculosis H37Rv | Rv3781 | rfbE | 1e-138 | 91.39% (267) | o-antigen/lipopolysaccharide transport ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_0203c | - | 1e-122 | 83.66% (257) | o-antigen/lipopolysaccharide transport ATP-binding protein ABC |
| M. marinum M | MMAR_5336 | rfbE | 1e-135 | 88.85% (278) | O-antigen/lipopolysaccharide transport ATP- binding protein |
| M. avium 104 | MAV_0238 | - | 1e-132 | 92.80% (250) | O-antigen export system ATP-binding protein RfbB |
| M. smegmatis MC2 155 | MSMEG_6366 | - | 1e-130 | 89.58% (259) | O-antigen export system, ATP-binding protein |
| M. thermoresistible (build 8) | TH_1668 | - | 1e-130 | 88.89% (261) | PROBABLE O-ANTIGEN/LIPOPOLYSACCHARIDE TRANSPORT ATP-BINDING |
| M. ulcerans Agy99 | MUL_0092 | rfbE | 1e-134 | 88.49% (278) | O-antigen/lipopolysaccharide transport ATP- binding protein |
| M. vanbaalenii PYR-1 | Mvan_5618 | - | 1e-129 | 88.42% (259) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1186|M.gilvum_PYR-GCK MTRPADEPFIETRNAWVEFPIFDAKTRSLKKAFLGKAGGAIGRNDSNVVV
Mvan_5618|M.vanbaalenii_PYR-1 MS--PDEPYIETRNAWVEFPIFDAKTRSLKKAFLGKAGGAIGRNESNVVV
MSMEG_6366|M.smegmatis_MC2_155 MTS-SSAPRIETRDAWVEFPIFDAKTRSLKKAFLGKAGGAIGRNQSNVVV
TH_1668|M.thermoresistible__bu ----VSHPSIETRNAWVEFPIFDAKSRSLKKAFLGKAGGAIGRNASNVVV
Mb3810|M.bovis_AF2122/97 -MSDPHHPHIQTHNAWVEFPIFDAKSRSLKKAVLGKAGGTIGRNNSNVVV
Rv3781|M.tuberculosis_H37Rv -MSDPHHPHIQTHNAWVEFPIFDAKSRSLKKAVLGKAGGTIGRNNSNVVV
MLBr_00114|M.leprae_Br4923 -MVEG--PHIETNNAWVEFPIFDAKARSLKKAVLGKAGGTIGRNNSNVVV
MAV_0238|M.avium_104 ----------------MEFPIFDAKSRSLKKAFLGKAGGTIGRNNSNVVV
MMAR_5336|M.marinum_M -MSEL--PRIETRDAWVEFPIFDAKSRSLKKAFLGKAGGSIGRNSSNVVV
MUL_0092|M.ulcerans_Agy99 -MSEL--PRIETRDAWVEFPIFDAKSRSLKKAFLGKAGGSIGRNSSNVVV
MAB_0203c|M.abscessus_ATCC_199 ------MVSIQTHQAWVEFPIFDAKSRSLKKAFLGKAGGAIGRNESNVVV
:********:******.******:**** *****
Mflv_1186|M.gilvum_PYR-GCK IEALRDITLSLKMGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGVAEVRGR
Mvan_5618|M.vanbaalenii_PYR-1 IEALRDITMSLKMGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGVATVRGR
MSMEG_6366|M.smegmatis_MC2_155 IEALRDITMSLEMGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGSATVSGR
TH_1668|M.thermoresistible__bu IEALRDITMSLKLGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGSAVVNGR
Mb3810|M.bovis_AF2122/97 IEALRDITMELNLGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGWAKVTGR
Rv3781|M.tuberculosis_H37Rv IEALRDITMELNLGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGWAKVTGR
MLBr_00114|M.leprae_Br4923 IEALRDITMSLSVGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGWAKVTGR
MAV_0238|M.avium_104 VEALRDITMSLELGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGWAQVTGR
MMAR_5336|M.marinum_M IEALRDITMSLEHGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGLAKVTGR
MUL_0092|M.ulcerans_Agy99 IEALRDITMSLEHGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGLAKVTGR
MAB_0203c|M.abscessus_ATCC_199 IEALRDITLSLKEGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGSSYIKGR
:*******:.*. ****************************** : : **
Mflv_1186|M.gilvum_PYR-GCK VAPVFDLGVGMDPEISGFENIIIRGLFLGQTRKQMLAKVDEIAEFTELGD
Mvan_5618|M.vanbaalenii_PYR-1 VAPVFDLGVGMDPEISGFENIIIRGLFLGQTRKQMMSKVDEIAEFTELGD
MSMEG_6366|M.smegmatis_MC2_155 VAPVFDLGVGMDPEISGFENIIIRGLFLGQTRKQMLAKVDEIAEFTELGE
TH_1668|M.thermoresistible__bu VAPVFDLGVGMDPEISGFENIIIRGLFLGQTRKQMLAKIDEIAEFTELGE
Mb3810|M.bovis_AF2122/97 VAPVFDLGIGMDPEISGYENIIIRGLFLGQTRKQMQAKVDEIAEFTELGE
Rv3781|M.tuberculosis_H37Rv VAPVFDLGIGMDPEISGYENIIIRGLFLGQTRKQMQAKVDEIAEFTELGE
MLBr_00114|M.leprae_Br4923 VAPVFDLGIGMDPEISGYENIIIRGLFLGQTRKQMLGKVDEIAEFTELGD
MAV_0238|M.avium_104 VAPIFDLGVGMDPEISGYENIIIRGLFLGQTRKQMLAKVDEIAEFTELGD
MMAR_5336|M.marinum_M VAPVFDLGIGMDPEISGYENIIIRGLFLGQTRKQMLAKVDEIAEFTELGD
MUL_0092|M.ulcerans_Agy99 VAPVFDLGIGMDPEISGYENIIIRGLFLGQTRKQMLAKVDEIAEFTELGD
MAB_0203c|M.abscessus_ATCC_199 VAPVFDLGVGMDPEISGYENIIIRGMFLGQTRKQMQAKVDEIADFTELGE
***:****:********:*******:********* .*:****:*****:
Mflv_1186|M.gilvum_PYR-GCK YLNMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDAEFLKKAQTR
Mvan_5618|M.vanbaalenii_PYR-1 YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDAEFLKKAQTR
MSMEG_6366|M.smegmatis_MC2_155 YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDAEFLKKAQSR
TH_1668|M.thermoresistible__bu YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDAEFLKKAQSR
Mb3810|M.bovis_AF2122/97 YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDADFLRKAQSR
Rv3781|M.tuberculosis_H37Rv YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDADFLRKAQSR
MLBr_00114|M.leprae_Br4923 YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGSVDTDFLKKAQSR
MAV_0238|M.avium_104 YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGLGAVDADFMKKAQSR
MMAR_5336|M.marinum_M YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDAEFLKKAQSR
MUL_0092|M.ulcerans_Agy99 YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDAGFLKKAQSR
MAB_0203c|M.abscessus_ATCC_199 YLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDAEFMKKARIR
**.********************************:*:**: *::**: *
Mflv_1186|M.gilvum_PYR-GCK LADLVARSGILVFASHSNEFLARLCDTAMWIDHGTIRMQGEIEDVVRAYE
Mvan_5618|M.vanbaalenii_PYR-1 LADLVERSGILVFASHSNEFLARLCNTAMWIDHGTIKMEGGIEEVVRGYE
MSMEG_6366|M.smegmatis_MC2_155 LQDLVERSGILVFASHSNEFLARLCKTAMWIDHGTIRMTGGIEEVVRAYE
TH_1668|M.thermoresistible__bu LQALVERSGILVFASHSNEFLARLCNTAMWIDHGTIKMTGSIEEVVRAYE
Mb3810|M.bovis_AF2122/97 LQNLVERSGILVFASHSNEFLARLCKTAIWIDHGVIRLAGGIEEVVRAYE
Rv3781|M.tuberculosis_H37Rv LQNLVERSGILVFASHSNEFLARLCKTAIWIDHGVIRLAGGIEEVVRAYE
MLBr_00114|M.leprae_Br4923 LQSLVERSGILVFASHSNEFLARLCKTAMWIDHGVIELSGGIEDVVRAYE
MAV_0238|M.avium_104 LQGLVERSGILVFASHSNEFLARLCKTAMWIDHGEIRMSGGIEDVVRAYE
MMAR_5336|M.marinum_M LQSLVERSGILVFASHSNEFLARLCKTAMWIDHGEIKLSGGIEDVVRAYE
MUL_0092|M.ulcerans_Agy99 LQSLVERSGILVFASHSNEFLARLCKTAMWIDHGEIKLSGGIKDVVRAYE
MAB_0203c|M.abscessus_ATCC_199 LQQLVERSGMLVFASHSNEFLARLCNTAMWIDHGTIKMSGGIEDVVRAYE
* ** ***:***************.**:***** *.: * *::***.**
Mflv_1186|M.gilvum_PYR-GCK GEDAARHVREVLEENKRE-------NRSA----
Mvan_5618|M.vanbaalenii_PYR-1 GEDAARHVREVLEETAHT-------HEH-----
MSMEG_6366|M.smegmatis_MC2_155 GEDAARHVREVLEETARD-------AH------
TH_1668|M.thermoresistible__bu GEDAARHVREVIAETRGE-------SVGHD---
Mb3810|M.bovis_AF2122/97 GEDAARHVREVLAETQAD-------RQNVQG--
Rv3781|M.tuberculosis_H37Rv GEDAARHVREVLAETQAD-------RQNVQG--
MLBr_00114|M.leprae_Br4923 GEDAARHVREVIAETAS--------AQNASGDE
MAV_0238|M.avium_104 GEDAARHVREVLAETAEQ-------P-------
MMAR_5336|M.marinum_M GEDAARHVRDVLAETQRDNIAQQPLAHKASGDE
MUL_0092|M.ulcerans_Agy99 GEDAARHVRDVLAETQRDNVAQQPLAHKASGDE
MAB_0203c|M.abscessus_ATCC_199 GDEAGDHVAQILAEDAHDG--------------
*::*. ** ::: *