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M. leprae Br4923 MLBr_00073 (-)

annotation: hypothetical protein MLBr_00073
coordinates: 94119 - 95153
length: 344

VIQVCSQCGTRWNVRERRREWCLRCRGALIAPQAEMPTAVKQWSSHVGLPAGIVPEALGWQRTPPGFRWI
AVRPGAAPPNRRRQRHHVPTPRYAVMPRWGLADRVDQDSTWIQAPLKPGPSSAKVRTTLFVAVLVFTLAA
LVYVVRYVLLVINRNTLLNFGVAAIADWLGVIASLAAIAATLACVMALSRWLIARRAAAYAHHAVPEQRS
SWELRAGCLLPLVNLLWAPVYVIELALMENHYTQLQKPIFMWWIVWVFSYVISVVAVVTSWAKDAQGIAN
NTVAMVFAYLFAAAAVAAVARVFEGFECKSIKRPVHRWVVVHLGGSVVHPSPGSVELEGQEPAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00073--100% (344)hypothetical protein MLBr_00073

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3873c-1e-11863.32% (349) transmembrane protein
M. gilvum PYR-GCKMflv_1139-1e-8848.99% (347) hypothetical protein Mflv_1139
M. tuberculosis H37RvRv3843c-1e-11863.32% (349) transmembrane protein
M. abscessus ATCC 19977MAB_0122-3e-5735.44% (364) hypothetical protein MAB_0122
M. marinum MMMAR_5395-1e-10856.58% (357) hypothetical protein MMAR_5395
M. avium 104MAV_0184-2e-9161.31% (274) hypothetical protein MAV_0184
M. smegmatis MC2 155MSMEG_6424-1e-6842.86% (350) transmembrane protein
M. thermoresistible (build 8)TH_4282-1e-5346.44% (239) PUTATIVE conserved hypothetical protein
M. ulcerans Agy99MUL_5016-1e-10956.30% (357) hypothetical protein MUL_5016
M. vanbaalenii PYR-1Mvan_5668-2e-8748.55% (346) hypothetical protein Mvan_5668

CLUSTAL 2.0.9 multiple sequence alignment


MLBr_00073|M.leprae_Br4923          MIQVCSQCGTRWNVRERRREWCLRCRGALIAP------------------
MAV_0184|M.avium_104                --------------------------------------------------
Mb3873c|M.bovis_AF2122/97           MIQVCSQCGTRWNVRERQRVWCPRCRGMLLAP------------------
Rv3843c|M.tuberculosis_H37Rv        MIQVCSQCGTGWNVRERQRVWCPRCRGMLLAP------------------
MMAR_5395|M.marinum_M               MIQVCSQCGTRWNVRERQRVWCPRCRGALMAP------------------
MUL_5016|M.ulcerans_Agy99           MIQVCSQCGTRWNVRERQRVWCPRCRGALMAP------------------
Mflv_1139|M.gilvum_PYR-GCK          MIQVCSQCGTRWNVRDRQRVWCPRCRGTLLAP------------------
Mvan_5668|M.vanbaalenii_PYR-1       MIQVCSQCGTRWNVRDRQRVWCPRCRGTLLAP------------------
TH_4282|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6424|M.smegmatis_MC2_155      MIQVCSQCGTRWNVRERQRSWCPRCGGGLLAP------------------
MAB_0122|M.abscessus_ATCC_1997      MIQVCSRCGTQWNVREQRRYWCPRCRGTLLEPGMTAPPRPAASMSRPPVG
                                                                                      

MLBr_00073|M.leprae_Br4923          -QAEMPTAVKQWSSHVGLPAGIVPEALGWQRTPPGFRWIAVRPGAAPPNR
MAV_0184|M.avium_104                ----------------------------------------MRPGAAPPPR
Mb3873c|M.bovis_AF2122/97           -LADMPAEARWRTPARPQVPTASDTRRTPPRLPPGFRWIAVRPGAAPPPR
Rv3843c|M.tuberculosis_H37Rv        -LADMPAEARWRTPARPQVPTASDTRRTPPRLPPGFRWIAVRPGAAPPPR
MMAR_5395|M.marinum_M               -LTGAAAADPQSRTSVGPQRVASTARRAAPRLPPGFRWIAVRPGAAPPHR
MUL_5016|M.ulcerans_Agy99           -LTGAAAADPQSRTSVGPQRVASTARRAAPRLPPGFRWIAVRPGAAPPHR
Mflv_1139|M.gilvum_PYR-GCK          -SGPAPAQG-----WDQRPA---------ARPPAGYRWVAVRPGAPPRPR
Mvan_5668|M.vanbaalenii_PYR-1       -SGHAAGHG-----WDPRQASPQDAPRQGARLPSGYRWVAVRPGAPPRPP
TH_4282|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6424|M.smegmatis_MC2_155      -SAPE-------SQWASPPRQPQQPQRPPARLAPGYRWIAVRPGAPPPSR
MAB_0122|M.abscessus_ATCC_1997      APAPAGKYWVPPTQQGPVATPAGRPQARPTRLPAGYRWIAVRPGSPPAPA
                                                                                      

MLBr_00073|M.leprae_Br4923          RRQRHHVPTPRYAVMPRWGLADRVD-QDSTWIQAPLKPGPSSAKVRTTLF
MAV_0184|M.avium_104                RGRRPLGPTPRYAVIPRWGLADRVE-PPPAVAAASAHPGPPAQLVRSTSF
Mb3873c|M.bovis_AF2122/97           HGPRLRGPTPHYAGIPRWGLTDHVD-QAP--VPASAKAGPSPAAVRTTLL
Rv3843c|M.tuberculosis_H37Rv        HGPRLRGPTPRYAGIPRWGLTDHVD-QAP--VPASAKAGPSPAAVRTTLL
MMAR_5395|M.marinum_M               PRRRAYGPTPRYTVMPRWGLGDRVAQPGPSPVPVATKTGPAAATVRTLLF
MUL_5016|M.ulcerans_Agy99           PRRRAYGPTPRYTVMPRWGLGDRVAQPGPLPVPVATKTGPAAATVRTLLF
Mflv_1139|M.gilvum_PYR-GCK          RVRRELGPTPRYQSIPRWGLVEHFD---APAEQTAERTGPSANAVRALLL
Mvan_5668|M.vanbaalenii_PYR-1       RRRRDLGPTPRYLSIPRWGLVERFD---VPVEDAAQRKGPSVNAVQMTLV
TH_4282|M.thermoresistible__bu      --------------------VEHFD---TAPQDAGPEPGASAALVRGVLI
MSMEG_6424|M.smegmatis_MC2_155      PRRRPLGPTPRYLTVPRWGLHQDFA--VAEERQQAQRTGPAAHTVRLVIV
MAB_0122|M.abscessus_ATCC_1997      RRRRPLGPTPRYAYIPRWGLVDHIEPTGSSRQGIAGGAVPS-RILDRLLL
                                                         : .               ..   :    .

MLBr_00073|M.leprae_Br4923          VAVLVFTLAALVYVVRYVLLVINRNTLLNFGVAAIADWLGVIASLAAIAA
MAV_0184|M.avium_104                VGVLVLGIAALVYVVRYLLLVINRDTLLYSWVAIGADWLGVLASVGAVGA
Mb3873c|M.bovis_AF2122/97           VSLLVFSIAVVVFVVRYVLLVINRNTLLNSVVASASVWLGVLVSLAAIAA
Rv3843c|M.tuberculosis_H37Rv        VSLLVFSIAVVVFVVRYVLLVINRNTLLNSVVASASVWLGVLVSLAAIAA
MMAR_5395|M.marinum_M               ATMLVLGAAAFVYAVRYVLLIINRDILLNSVLAGIAVWVGVAVSFAALAA
MUL_5016|M.ulcerans_Agy99           ATMLVLGAAAFVYAVRYVLLIINRDILLNSVLAGIAVWVGVAVSFAALAA
Mflv_1139|M.gilvum_PYR-GCK          VTMAALGAAAFVHVVRYILLIVNRTVLLPPWLAAAATWGGVAVSVVAVFT
Mvan_5668|M.vanbaalenii_PYR-1       ATMAVLGAAAFVHVVRYVLLIVNRSVLLNPWIAGAATWGGVAVSVVAVFL
TH_4282|M.thermoresistible__bu      LTMVILGAAAFAHIVRYVLLLINRSTLLHPWVAAVATWLPVALSVAAMFA
MSMEG_6424|M.smegmatis_MC2_155      LAMIALAGAAFAHIVRYILLLVNRTVLLHPVIAWGGVLLGMLASLLVLAI
MAB_0122|M.abscessus_ATCC_1997      ATIITLAITSCTHFLRYALMVYNRGALIPRFVASASNGLVLISVALAFAV
                                      :  :  :  .. :** *:: **  *:   :*  .    :     ..  

MLBr_00073|M.leprae_Br4923          TLACVMALSRWLIARRAAAYAHHAVPEQRSSWELRAGCLLPLVNLLWAPV
MAV_0184|M.avium_104                VIASGVALIRWMIARRAAVFAHHGLPDPRSARALGAGCVVPLANLLWAPV
Mb3873c|M.bovis_AF2122/97           AGTTIVLLVRWLVARRAAAFMHQGLPERRSARELWAGCLLPMVNLLWAPL
Rv3843c|M.tuberculosis_H37Rv        AGTTIVLLVRWLVARRAAAFMHQGLPERRSARELWAGCLLPMVNLLWAPL
MMAR_5395|M.marinum_M               MGVCFVVLIKWLVARRAAAFAYYGLPEHRSTLQLWAGCLTPLANLLWAPV
MUL_5016|M.ulcerans_Agy99           MGVCFVVLIKWLVARRAVAFAYYGLPEHRSTLQLWAGCLTPLANLLWAPV
Mflv_1139|M.gilvum_PYR-GCK          VVASALMLTNWLIARRAAAYAHRGHQDPRSAASLRLGCLVPVANLLWAPV
Mvan_5668|M.vanbaalenii_PYR-1       TVASLVVLTNWLIARRSAAFAHQGHRDPRSAWVLRLGCLTPFVNLFWAPV
TH_4282|M.thermoresistible__bu      VVTTILVLTNWLIARRAATYRRLGTSDPRPVWMLWTGCVLPVVNLIVAPV
MSMEG_6424|M.smegmatis_MC2_155      MTITVVMLISWLVARRREAYSQRGQEDPRSPLELWICALAPVVNLFMAPV
MAB_0122|M.abscessus_ATCC_1997      MAATAWFLTDWMIARRAETYRDLGFDDPRSPWEIRVLCLLPIANIVGIPL
                                           *  *::***  .:   .  : *.   :   .: *..*:.  *:

MLBr_00073|M.leprae_Br4923          YVIELALMENHYTQLQKPIFMWWIVWVFSYVISVVAVVTS-----WAKDA
MAV_0184|M.avium_104                FVIELALLEEHYHRLKGPILQWWITWVCSYAVSVSAIATS-----FVTDA
Mb3873c|M.bovis_AF2122/97           YVIELALVEDRYTRLRRPIVVWWIVWIVSNAISMFAFATS-----WVTDA
Rv3843c|M.tuberculosis_H37Rv        YVIELALVEDRYTRLRRPIVVWWIVWIVSNAISMFAFATS-----WVTDA
MMAR_5395|M.marinum_M               YLIELAVVEDTYQRLKKPILVWWIAWVVSTATSLFAIATS-----FSSDA
MUL_5016|M.ulcerans_Agy99           YLIELAVVEDTYQRLKKPILVWWIAWVVSTATSLFAIATS-----FSSDA
Mflv_1139|M.gilvum_PYR-GCK          YVIELADTEARLRWLHRSILLWWVVWVVSTAVSIFSIATS-----FTTDP
Mvan_5668|M.vanbaalenii_PYR-1       YVMELADAEGRQRWLHRPIVVWWLFWVASTTVTTFAFATS-----FTADA
TH_4282|M.thermoresistible__bu      FIFELAKAEDRLSWLRRPVYVFWAAWLVSHVISGCAFFTS-----FARDA
MSMEG_6424|M.smegmatis_MC2_155      FVLELARADNRMTLLRRPIAVWWIVWVLSAIVATWSIVSTVYVTFFNNTP
MAB_0122|M.abscessus_ATCC_1997      LLLELAKIENRWYRQYRNIMWWTVLWAATWLLALVTWVVR-----DSVTV
                                     ::***  :         :  :   *  :   :  :              

MLBr_00073|M.leprae_Br4923          QGIANNTVAMVFAYLFAAAAVAAVARVFEGFECKSIK-RPVHRWVVVHLG
MAV_0184|M.avium_104                QGIANNTILMVFGYLFAAATLAAATRIFEGFQRKPVA-RPAHRWVMVPDD
Mb3873c|M.bovis_AF2122/97           QGIANNTTMMVLAYLCAAAAVAAAARVFEGFEQKPVE-RPAHRWVVVNTD
Rv3843c|M.tuberculosis_H37Rv        QGIANNTTMMVLAYLCAAAAVAAAARVFEGFEQKPVE-RPAHRWVVVNTD
MMAR_5395|M.marinum_M               QGIANNTVMVVVAYALAAAAVGTVSRVFEGFERKPVQ-RPAHRWLVMGQD
MUL_5016|M.ulcerans_Agy99           QGIANNTVMVVVAYALAAAAVGTVSRVFEGFECKPVQ-RPAHRWLVMGQD
Mflv_1139|M.gilvum_PYR-GCK          QGIADNTVVTIVAYLFGLAALVLVQRVFDGFEQQPVS-RPSHRWVVV---
Mvan_5668|M.vanbaalenii_PYR-1       QGIADNTVTTIVAYLFAAAALLSALRVFLGFERQPVQ-RPSRRWVTV---
TH_4282|M.thermoresistible__bu      QGIADNTVITVVAYLAALAVVVLVARVHDSFDRTPVE-RPARRWVVVPDQ
MSMEG_6424|M.smegmatis_MC2_155      QNIADNTVTVIIGYLLGLTTLLLTYRVFQGFEATEAQGRSVRRWVVVAEG
MAB_0122|M.abscessus_ATCC_1997      QGIADNALFTAIDYAVAAVAAWRLRRVYEGFTAPEGH-HRAVRWLAVESP
                                    *.**:*:    . *  . ..     *:. .*       :   **: :   

MLBr_00073|M.leprae_Br4923          GS------------------------------------------VVHPSP
MAV_0184|M.avium_104                G-------------------------------------------PPPPAP
Mb3873c|M.bovis_AF2122/97           G-------------------------------------------RSAPAS
Rv3843c|M.tuberculosis_H37Rv        G-------------------------------------------RSAPAS
MMAR_5395|M.marinum_M               DQPGRS-------------------------------ATDEDDRVDAAPD
MUL_5016|M.ulcerans_Agy99           DQPGRS-------------------------------ATDEDDRVDAAPD
Mflv_1139|M.gilvum_PYR-GCK          -------------------------------------GAPQDGEVDDTQP
Mvan_5668|M.vanbaalenii_PYR-1       -------------------------------------RVD-AGESDDAEP
TH_4282|M.thermoresistible__bu      TAE-PG-------------------------------RPGGSEEHADGSS
MSMEG_6424|M.smegmatis_MC2_155      AKPPAGPGGPHGSGPAGRSTEEADESTDTADTPAEGDTEPADEQPQRPES
MAB_0122|M.abscessus_ATCC_1997      QGPVPLDAD-----------------------------RPDVPPTRDANS
                                                                                      

MLBr_00073|M.leprae_Br4923          GS-VELEGQEPAA----------
MAV_0184|M.avium_104                GAPVEFKGQEPAA----------
Mb3873c|M.bovis_AF2122/97           SVAVELDGQEPAA----------
Rv3843c|M.tuberculosis_H37Rv        SVAVELDGQEPAA----------
MMAR_5395|M.marinum_M               ADAVELEGQEPAA----------
MUL_5016|M.ulcerans_Agy99           ADAFELEGQEPAA----------
Mflv_1139|M.gilvum_PYR-GCK          ARAVETDGQNPAA----------
Mvan_5668|M.vanbaalenii_PYR-1       ARAVESNGENPAA----------
TH_4282|M.thermoresistible__bu      APPVEAGGQNPAA----------
MSMEG_6424|M.smegmatis_MC2_155      SVPVEPAGQNPAA----------
MAB_0122|M.abscessus_ATCC_1997      GAAVEPVGTEPAALDRDRVVGAW
                                    .  .*  * :***