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LTELIDLPGGAFLMGSNSFYPEESPVHEVTVRPFSIERHPVTNAQFAEFVDQTGYVTVAEKALDPKDFPG VPAEDLKPGALVFTPTAGPVDLRAWRQWWTWMPGACWRQPFGPGSSIEDRLDHPVVQVAYPDAAAYASWA GRRLPSEAQWEYAARAGTSSAYAWGDDVAPGGEIMANTWQGKFPYRNDGARGWTGTSPVGTFAPNGFGLV DMIGNVWEWTSTRYSAGHHPGRAAPSCCPTSPTGDPAVLQTLKGGSHLCAPEYCHRYRPAARSSQSQDSA TTHIGFRCIAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5033 | - | - | 100% (292) | sulfatase-modifying factor 1 |
| M. avium 104 | MAV_4458 | - | e-134 | 73.01% (289) | sulfatase-modifying factor 1 |
| M. avium 104 | MAV_0400 | - | 9e-16 | 29.13% (230) | hypothetical protein MAV_0400 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0733 | - | 1e-132 | 71.77% (294) | hypothetical protein Mb0733 |
| M. gilvum PYR-GCK | Mflv_5038 | - | 1e-132 | 73.47% (294) | hypothetical protein Mflv_5038 |
| M. tuberculosis H37Rv | Rv0712 | - | 1e-132 | 71.77% (294) | hypothetical protein Rv0712 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4305 | - | 1e-129 | 71.63% (289) | hypothetical protein MAB_4305 |
| M. marinum M | MMAR_1043 | - | 1e-134 | 72.51% (291) | hypothetical protein MMAR_1043 |
| M. smegmatis MC2 155 | MSMEG_1226 | - | 1e-143 | 78.69% (291) | sulfatase-modifying factor 1 |
| M. thermoresistible (build 8) | TH_0314 | - | 1e-132 | 72.73% (297) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0225 | - | 4e-91 | 55.86% (290) | hypothetical protein MUL_0225 |
| M. vanbaalenii PYR-1 | Mvan_1319 | - | 1e-129 | 72.32% (289) | hypothetical protein Mvan_1319 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5033|M.avium_104 ------------------MLTELIDLPGGAFLMGSNSFYPEESPVHEVTV
MSMEG_1226|M.smegmatis_MC2_155 ------------------MLTELVALDGGTFRMGSQDFYPEEAPVHEVSV
Mb0733|M.bovis_AF2122/97 ------------------MLTELVDLPGGSFRMGSTRFYPEEAPIHTVTV
Rv0712|M.tuberculosis_H37Rv ------------------MLTELVDLPGGSFRMGSTRFYPEEAPIHTVTV
MMAR_1043|M.marinum_M ------------------MLTELVDLPGGSFRMGSTSFYPEEAPIHSVSV
Mflv_5038|M.gilvum_PYR-GCK ------------------MLTDLVDLEGGSFRMGSTRFYPEEAPAHTVTV
Mvan_1319|M.vanbaalenii_PYR-1 ------------------MLTELVALDGGSFRMGSTRFYPEEAPVHTVTV
TH_0314|M.thermoresistible__bu ----------------MSALTDLVEIPGGTFRMGSIRFYPEEAPVHTVTV
MAB_4305|M.abscessus_ATCC_1997 MEYSPRNRKLREMETAAVTLTELVELPGGSFPMGCNVFYPEEMPERVSSV
MUL_0225|M.ulcerans_Agy99 ------------------MTDDLIRIPAQTAVLGSEAHYPEESPLRQVDV
:*: : . : :*. .**** * : *
MAV_5033|M.avium_104 RPFSIERHPVTNAQFAEFVDQTGYVTVAEKALDPKDFPGVPAEDLKPGAL
MSMEG_1226|M.smegmatis_MC2_155 APFSIERHPVTNAQFAEFVAATGYVTVAEQELDPAAFPGVPADELVPGAL
Mb0733|M.bovis_AF2122/97 RAFAVERHPVTNAQFAEFVSATGYVTVAEQPLDPGLYPGVDAADLCPGAM
Rv0712|M.tuberculosis_H37Rv RAFAVERHPVTNAQFAEFVSATGYVTVAEQPLDPGLYPGVDAADLCPGAM
MMAR_1043|M.marinum_M HAFAIERYPVTNAQFAEFVAATGYVTVAEQPLDPALYPGVNPDDLRPGAM
Mflv_5038|M.gilvum_PYR-GCK APFAIERNPVTNAQFAEFVDDTGYRTVAERPPDPALYPGASPHDLVPGAL
Mvan_1319|M.vanbaalenii_PYR-1 APYAIERHPVTNAQFASFVADTGYRTVAELAPDPALYPGAAPQDLVPGAL
TH_0314|M.thermoresistible__bu ADFAIERHPVTNAQFAEFVAATGYRTVAEQPLDPRLYPGVAAADLQPGAL
MAB_4305|M.abscessus_ATCC_1997 EPFAIERHPVTNAQFAEFVTQTGYVTVAERAPDPDMYPGASPDDLVPGAM
MUL_0225|M.ulcerans_Agy99 NAFRIQAHQVTNTQFAEFVDATGYLTVAERPLDPADYPGAPPENLQPGSM
: :: ***:***.** *** **** ** :**. . :* **::
MAV_5033|M.avium_104 VFTPTAGPVDLRAWRQWWTWMPGACWRQPFGP-GSSIEDRLDHPVVQVAY
MSMEG_1226|M.smegmatis_MC2_155 VFQPTEGPVNLRDWRQWWTWVPGACWKHPKGP-GSSIDDVPDHPVVQVAY
Mb0733|M.bovis_AF2122/97 VFCPTAGPVDLRDWRQWWDWVPGACWRHPFGR-DSDIADRAGHPVVQVAY
Rv0712|M.tuberculosis_H37Rv VFCPTAGPVDLRDWRQWWDWVPGACWRHPFGR-DSDIADRAGHPVVQVAY
MMAR_1043|M.marinum_M VFRPTAGPVDLRDWRQWWDWAPGASWRHPWGP-DSDVDDRADHPVVQVAY
Mflv_5038|M.gilvum_PYR-GCK VFRPTAGPVDLRDWRQWWEWTPGADWRHPFGP-DSSVDDRPEHPVVQVCY
Mvan_1319|M.vanbaalenii_PYR-1 VFRPTAGPVDLTDWRQWWEWVPGADWRHPSGP-GSSVDDKPDHPVVQVCY
TH_0314|M.thermoresistible__bu VFTPTRGPVDLRDWRQWWTWTPGACWRHPFGPEGPSWQDRPDHPVVQIAY
MAB_4305|M.abscessus_ATCC_1997 TFRTTAGPVDLHDWQQWWDWVPGAYWRHPFGP-GSDIDGAAEHPVVQVAY
MUL_0225|M.ulcerans_Agy99 VFTRTAGPVDLRHLSLWWTWTPGASWRHPAGP-HSSIAKRADHPVVHVAY
.* * ***:* ** * *** *::* * .. ****::.*
MAV_5033|M.avium_104 PDAAAYASWAGRRLPSEAQWEYAARAGTS-SAYAWGDDVAPGGEIMANTW
MSMEG_1226|M.smegmatis_MC2_155 PDAAAYAAWAGRRLPTEAEWEYAARAGAT-TVYAWGDDVRPDGQLMANTW
Mb0733|M.bovis_AF2122/97 PDAVAYARWAGRRLPTEAEWEYAARGGTT-ATYAWGDQEKPGGMLMANTW
Rv0712|M.tuberculosis_H37Rv PDAVAYARWAGRRLPTEAEWEYAARGGTT-ATYAWGDQEKPGGMLMANTW
MMAR_1043|M.marinum_M PDAAAYARWAGRRLPTEAEWEYAARGATT-TTYAWGDEEKPAGQLMANTW
Mflv_5038|M.gilvum_PYR-GCK SDAAAYARWAGRRLPTEAEWEFAAGAGST-AVYAWGDEPAPGGQLMANTW
Mvan_1319|M.vanbaalenii_PYR-1 ADAAAYARWAGRRLPTEAEWEFAARAGST-AVYAWGDEAVPGGALMANTW
TH_0314|M.thermoresistible__bu PDAQAYARWAGRRLPTEREWEYAARAGAD-TVYPWGDEARPGGRLMANTW
MAB_4305|M.abscessus_ATCC_1997 TDAAAYARWAGRRLPTEAEWEYAARGGSG-TVYAWGDEVAPEGRLMANTW
MUL_0225|M.ulcerans_Agy99 EDAHAYAGWAGLALPSEAEWEVAARGGLTGAAYTWGEESERPGQRLANFW
** *** *** **:* :** ** .. :.*.**:: * :** *
MAV_5033|M.avium_104 QGKFPYRNDGARGWTGTSPVGTFAPNGFGLVDMIGNVWEWTSTRYSAGHH
MSMEG_1226|M.smegmatis_MC2_155 QGRFPYRNDGALGWTGTSPVGTFPPNGFGLVDMIGNVWEWTSTRYTPRHS
Mb0733|M.bovis_AF2122/97 QGRFPYRNDGALGWVGTSPVGRFPANGFGLLDMIGNVWEWTTTEFYPHHR
Rv0712|M.tuberculosis_H37Rv QGRFPYRNDGALGWVGTSPVGRFPANGFGLLDMIGNVWEWTTTEFYPHHR
MMAR_1043|M.marinum_M QGKFPYRNDGALGWFGTSPVGTFPANGFGLFDMIGNVWEWTTTPFSAHHR
Mflv_5038|M.gilvum_PYR-GCK QGAFPYRNDGALGWAGTSPVGTFPANGFGLVDMIGNVWEWTTTRFAGHHR
Mvan_1319|M.vanbaalenii_PYR-1 QGAFPYRNDGALGWSGTSPVGTFPANAYGLVDMIGNVWEWTTTRFAGHHV
TH_0314|M.thermoresistible__bu QGRFPYRNDGAAGWIGTSPVGAFPPNDFGLFDMIGNVWEWTTTRFSGHHR
MAB_4305|M.abscessus_ATCC_1997 QGRFPYRNDGALGWHGTSPVGTFPANDFGLLDMIGNVWEWTSTRFQ--HG
MUL_0225|M.ulcerans_Agy99 HGDFPWRPE--PGYGRTSPVGSFEPNGYGLFDMAGNVWEWTVDWYIDTPS
:* **:* : *: ***** * .* :**.** ******* :
MAV_5033|M.avium_104 ----PGRAAPSCCPTSP---TGDPAVLQTLKGGSHLCAPEYCHRYRPAAR
MSMEG_1226|M.smegmatis_MC2_155 ----RRPEVSGCCP-AP---GGDPSIHQTLKGGSHLCAPEYCHRYRPAAR
Mb0733|M.bovis_AF2122/97 ---IDPPST-ACCAPVKLATAADPTISQTLKGGSHLCAPEYCHRYRPAAR
Rv0712|M.tuberculosis_H37Rv ---IDPPST-ACCAPVKLATAADPTISQTLKGGSHLCAPEYCHRYRPAAR
MMAR_1043|M.marinum_M ---IDQPPK-ACCAP---AGPADPTISQTLKGGSHLCAPEYCHRYRPAAR
Mflv_5038|M.gilvum_PYR-GCK ---VNPPPPPTCCPPAD----PDPAVNQALKGGSHLCAPEYCHRYRPSAR
Mvan_1319|M.vanbaalenii_PYR-1 ---LDAPVN-SCCPQAG----PDPAVTQTLKGGSHLCAPEYCHRYRPSAR
TH_0314|M.thermoresistible__bu PAEADEPVR-SCCTPSAPVERPDPAVSQTLKGGSHLCAPEYCHRYRASAR
MAB_4305|M.abscessus_ATCC_1997 ---AGAPKS--CCSPSD---NPDPSVIQVLKGGSHLCAPEYCHRYRPAAR
MUL_0225|M.ulcerans_Agy99 ---ARPAAEADSYDPQQ---PQFRVPRKVVKGGSFLCADSYCRRYRPAAR
. :.:****.*** .**:***.:**
MAV_5033|M.avium_104 SSQSQDSATTHIGFRCIAS----
MSMEG_1226|M.smegmatis_MC2_155 SSQSQDSATTHIGFRCVAG----
Mb0733|M.bovis_AF2122/97 SPQSQDTATTHIGFRCVADPVSG
Rv0712|M.tuberculosis_H37Rv SPQSQDTATTHIGFRCVADPVSG
MMAR_1043|M.marinum_M SPQSQDTATTHIGFRCVADR---
Mflv_5038|M.gilvum_PYR-GCK SPQSQDSATTHIGFRCAASPV--
Mvan_1319|M.vanbaalenii_PYR-1 SPQSQDSATTHIGFRCAV-----
TH_0314|M.thermoresistible__bu SPQSQDSAATHIGFRCAA-----
MAB_4305|M.abscessus_ATCC_1997 SPQSQDSATTHIGFRCVENLG--
MUL_0225|M.ulcerans_Agy99 RPQPIDTGVSHIGFRCVGRD---
.*. *:..:******