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MKSMQELFEIAWQATQIGATTLKKTQPSSVQHKGDRDLVSDVDLTIQRDIANYLSQTTPDVALLAEESDH QPDIETAEWLWVLDPVDGTSNFVHGLPLCAVSLALLHAGRTVVAVTHAPLLGKTYHAIESKGAFVNGERI TASATDSLSGAIVSLGDYAVGHDAGRLNAHRLALTAELVPRAERIRMIGAATLDLAFVAEGALDACVMMS NKPWDTAAGTLVAREAGARLTDAQGNPHTHKSASTVVAAPGIAEQLATVIRNTEVPSDRYAAAVG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4484 | - | - | 100% (275) | inositol monophosphatase family protein |
| M. avium 104 | MAV_3182 | - | 2e-32 | 34.85% (241) | inositol monophosphatase family protein |
| M. avium 104 | MAV_3593 | - | 4e-26 | 35.06% (231) | inositol-1-monophosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1630 | impA | 2e-29 | 32.37% (241) | inositol-monophosphatase |
| M. gilvum PYR-GCK | Mflv_3608 | - | 2e-31 | 34.02% (241) | inositol-phosphate phosphatase |
| M. tuberculosis H37Rv | Rv1604 | impA | 8e-31 | 32.78% (241) | inositol-monophosphatase |
| M. leprae Br4923 | MLBr_01024 | suhB | 1e-28 | 36.05% (233) | putative inositol monophosphatase |
| M. abscessus ATCC 19977 | MAB_2665c | - | 2e-31 | 33.05% (239) | inositol monophosphatase family protein |
| M. marinum M | MMAR_2400 | impA | 1e-34 | 34.02% (241) | inositol-monophosphatase ImpA |
| M. smegmatis MC2 155 | MSMEG_3210 | - | 2e-32 | 31.95% (241) | inositol monophosphate phosphatase |
| M. thermoresistible (build 8) | TH_1158 | impA | 2e-31 | 34.02% (241) | PROBABLE INOSITOL-MONOPHOSPHATASE IMPA (IMP) |
| M. ulcerans Agy99 | MUL_1577 | impA | 3e-34 | 33.61% (241) | inositol-monophosphatase ImpA |
| M. vanbaalenii PYR-1 | Mvan_2809 | - | 6e-33 | 32.78% (241) | inositol-phosphate phosphatase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3210|M.smegmatis_MC2_155 ---MTVVGELDPQKLTALVATAAEILDAASVPFVAGHRADS-----AVRK
TH_1158|M.thermoresistible__bu -------MALDDADLEALVSQAAKILDAASVRFVEGHRADS-----AVPK
Mflv_3608|M.gilvum_PYR-GCK -------MTLDRSQLVDLLTTAAGVLDGASAQFIDGHRADS-----AVAK
Mvan_2809|M.vanbaalenii_PYR-1 -------MSPEPQQLAELLDTAAGVLEAASAQFIAGHRADS-----AVAK
Mb1630|M.bovis_AF2122/97 -------MHLD-SLVAPLVEQASAILDAATALFLVGHRADS-----AVRK
Rv1604|M.tuberculosis_H37Rv -------MHLD-SLVAPLVEQASAILDAATALFLVGHRADS-----AVRK
MMAR_2400|M.marinum_M -------MDLA-ARLVTLVEQASAILDAAVPRFLGGHRADS-----AVPK
MUL_1577|M.ulcerans_Agy99 -------MDLA-ARLVTLVEQASAILDAAVPRFLGGHRADS-----AVPK
MAB_2665c|M.abscessus_ATCC_199 -------MTTT-AELEALVREASVILDAAAQRFVAGHGAEG-----VVFK
MAV_4484|M.avium_104 --------MKSMQELFEIAWQATQIG----ATTLKKTQPSS-----VQHK
MLBr_01024|M.leprae_Br4923 MTVPDNDPEQLRCVAESLATEAAAFVRCRRAEVFGTDLGAAGGGAVRAKS
: *: . . . .
MSMEG_3210|M.smegmatis_MC2_155 QGNDFATEVDLAIERQVVRALTEAT---GIGVHGEEFGG-----EPIDSP
TH_1158|M.thermoresistible__bu QGNDFATEVDLAIERQVVEALTGAT---GIGVHGEEFGG-----ADVTSP
Mflv_3608|M.gilvum_PYR-GCK KGNDFATEVDLAIERRVVAELNRLT---GIGVHGEEFGG-----ESLESE
Mvan_2809|M.vanbaalenii_PYR-1 KGNDFATEIDLAIERRVVAELTRLT---GIGVHGEEFGG-----ESVEAE
Mb1630|M.bovis_AF2122/97 KGNDFATEVDLAIERQVVAALVAAT---GIEVHGEEFGG-----PAVDSR
Rv1604|M.tuberculosis_H37Rv KGNDFATEVDLAIERQVVAALVAAT---GIEVHGEEFGG-----PAVDSR
MMAR_2400|M.marinum_M KGNDFATEVDLAIERQVVAALEAAT---GIGVHGEEFGG-----TDVDSP
MUL_1577|M.ulcerans_Agy99 KGNDFATEVDLAIERQVVAALVAAT---GIGVHGEEFGG-----TDVDSP
MAB_2665c|M.abscessus_ATCC_199 GGKDFATEEDLAIERMVVQALTERT---GIGVHGEEFGG-----PAVDSG
MAV_4484|M.avium_104 GDRDLVSDVDLTIQRDIANYLSQTTPDVALLAEESDHQP-----DIETAE
MLBr_01024|M.leprae_Br4923 TPTDPVTVVDTETERLLRDRLAQLRP--GDSILGEEGGGPADLTATPADT
* .: * :* : * . .:
MSMEG_3210|M.smegmatis_MC2_155 LVWVLDPIDGTFNYAAGSPMAAILLGLLADGEPVAGLTWLPFTGEKYSAL
TH_1158|M.thermoresistible__bu LVWVLDPIDGTFNYAAGLPLAAILLALLQDGEPVAGLTWMPFTDQRFTAI
Mflv_3608|M.gilvum_PYR-GCK QVWVLDPIDGTFNYAAGLPTAAILLGLLIDGEPVLGLTWLPFMDLRYTAI
Mvan_2809|M.vanbaalenii_PYR-1 YVWLLDPVDGTFNYAAGSPMAAILLSLLWEGKPLLGLTWLPFMGQRYTSM
Mb1630|M.bovis_AF2122/97 WVWVLDPIDGTINHAAGSPLAAILLGLLHDGVPVAGLTWMPFTDQRYTAV
Rv1604|M.tuberculosis_H37Rv WVWVLDPIDGTINYAAGSPLAAILLGLLHDGVPVAGLTWMPFTDPRYTAV
MMAR_2400|M.marinum_M WVWVLDPVDGTFNYAAGSPMAAILLGLLHEGEPVAGLTWLPFIGERYTAV
MUL_1577|M.ulcerans_Agy99 WVWVLDPVDGTFNYAAGSPMAAILLGLMHEGEPVAGLTWLPFIGERYTAV
MAB_2665c|M.abscessus_ATCC_199 LVWVVDPIDGTVNYAAGSPMAAILLGLMSDGVPVAGLTWLPFMGEKYAAV
MAV_4484|M.avium_104 WLWVLDPVDGTSNFVHGLPLCAVSLALLHAGRTVVAVTHAPLLGKTYHAI
MLBr_01024|M.leprae_Br4923 VTWVLDPIDGTVNFVYGIPAYAVSVAAQVDGVSVAGAVAEVVAGRVHSAA
*::**:*** *.. * * *: :. * .: . . . . . :
MSMEG_3210|M.smegmatis_MC2_155 VGGPLYSDGKPCPPLGSPTLADSIIGIQTFNIDSRGRFPGRYRVEVLANL
TH_1158|M.thermoresistible__bu AGKPLYLNGVEQPRLSDAGLADCVVGTGTFNVDSRGRFPGRYRVALLEAL
Mflv_3608|M.gilvum_PYR-GCK LGEQVRCNGAPLPGLEPVSLAESIVGTGTFNIDSRGRYPGRYRVKVLENL
Mvan_2809|M.vanbaalenii_PYR-1 VGAPVRCNGEELPRLAPTTLAESIVGTGTFNIDSRGRFPGRYRVKVLENL
Mb1630|M.bovis_AF2122/97 AGGPLIKNGVPQPPLADAELANVLVGVGTFSADSRGQFPGRYRLAVLEKL
Rv1604|M.tuberculosis_H37Rv AGGPLIKNGVPQPPLADAELANVLVGVGTFSADSRGQFPGRYRLAVLEKL
MMAR_2400|M.marinum_M AGGPLLRNGLPQASLAPAKLSESLMGVGTFSADSRGRFPGRYRLAVLENL
MUL_1577|M.ulcerans_Agy99 AGGPLLRNGLPQASLAPAKLSESLMGVGTFSADSRGRFPGRYRLAVLENL
MAB_2665c|M.abscessus_ATCC_199 TGGPLFRNGVAMPPLPRTDLADVAVGLGTFNVDWKGRVPGRYRLTVLEKL
MAV_4484|M.avium_104 ESKGAFVNGERITASATDSLSGAIVSLGDYAVGHDAGRLNAHRLALTAEL
MLBr_01024|M.leprae_Br4923 SGLGAHVTDEYGVQVLRCSAVDDLSMALLGTGFAYSVVRRAAQAALLAQM
. . . : : :
MSMEG_3210|M.smegmatis_MC2_155 SRVCSRVRMHGATGVDLAYVAAGILGGAISFGHHIWDHAAGVALVRAAGG
TH_1158|M.thermoresistible__bu SRRCNRIRMHGATGVDLAYTAAGILGGAISFGHHIWDHAAGVALIRSAGG
Mflv_3608|M.gilvum_PYR-GCK SRECSRMRMHGATGVDFAYVAAGVLGGAISFGHHIWDHAAGVALVRAAGG
Mvan_2809|M.vanbaalenii_PYR-1 SRECSRMRMHGSTGIDLAYVAAGILGGAISFGHHLWDHAAGVALVRAAGG
Mb1630|M.bovis_AF2122/97 SRVSSRLRMHGSTGIDLVFVADGILGGAISFGGHVWDHAAGVALVRAAGG
Rv1604|M.tuberculosis_H37Rv SRVSSRLRMHGSTGIDLVFVADGILGGAISFGGHVWDHAAGVALVRAAGG
MMAR_2400|M.marinum_M SRVSSRLRIHGSTGIDLVYVADGILGGAISFGGQVWDHAAGVAQVRAAGG
MUL_1577|M.ulcerans_Agy99 SRVSSRLRIHGSTGIDLVYVADGILGGAISFGGQVWDHAAGVAQVRAAGG
MAB_2665c|M.abscessus_ATCC_199 SRITSRLRMHGSTGIDLAFTAGGILGGAVSFGAHVWDHAAGIALVQAAGG
MAV_4484|M.avium_104 VPRAERIRMIGAATLDLAFVAEGALDACVMMSNKPWDTAAGTLVAREAGA
MLBr_01024|M.leprae_Br4923 LPVVRDVRRIGSAALDLCMVAAGQLDAYYEHEVQVWDCAAGALIAAEAGA
:* *:: :*: .* * *.. : ** *** **.
MSMEG_3210|M.smegmatis_MC2_155 VVTDLTGAPWTVDSKSVLAAAPGVHEKMLEIVKSTGKPEDYL-----
TH_1158|M.thermoresistible__bu VVTDLAGADWTIHSQSVLAGNPGVHAELLEIVQSVGDPEDYRR----
Mflv_3608|M.gilvum_PYR-GCK VVTDLDGEPWTASSPSALAAAPGVHEEILQLLRAAGDPKDYL-----
Mvan_2809|M.vanbaalenii_PYR-1 IVTDLAGETWTASSSSALAAAPGVHEEILALVRAAGDPKDYL-----
Mb1630|M.bovis_AF2122/97 VVTDLAGQPWTPASRSALAGPLRVHAQILEILGSIGEPEDY------
Rv1604|M.tuberculosis_H37Rv VVTDLAGQPWTPASRSALAGPPRVHAQILEILGSIGEPEDY------
MMAR_2400|M.marinum_M TVTTLTGDPWTPTSRSVLAAAPGVHEEILEIVRKTGDPEDY------
MUL_1577|M.ulcerans_Agy99 TVTTLTGDPWTPTSRSVLAAAPGVHEEILEIVRKTGDPEDY------
MAB_2665c|M.abscessus_ATCC_199 HASDLNGEPWTPESPSLLVAAPGVQEQILEVLAEVGDPEDYR-----
MAV_4484|M.avium_104 RLTDAQGNPHTHKSASTVVAAPGIAEQLATVIRNTEVPSDRYAAAVG
MLBr_01024|M.leprae_Br4923 CVQLPKRNGPVGGAGLVVAAAPGIADALLAALQRFNGLAPILD----
. : :.. : : :