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VPGDEAFRAAGCAGAGRLAGARCTAFVTDLSVWEAKMDAMPTLADPLTAGLDDEQREAVLAPRGPVCVLA GAGTGKTRTITHRIAQLVAGGHVAANQVLAVTFTQRAAGEMRSRLRALAAAAGTDAAVGSVSALTFHAAA HRQLRYFWPRVVGDTGWQLLDSKFAVVARAASRTRINASTDDVRDLAGEIEWAKASLIGPEEYPAAVAAA GRDIPLDAARVAGVYAAYEALKARGDHVTLLDFDDLLLHTAAAIENDPAVAEEFRDRYRCFVVDEYQDVT PLQQRVLAAWLGDRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDATVVRLERDYRSTPQVVSLANQV IAAARGRVAGSKLHLVGQRPPGPVPTFHEHPDEPAEAAAVAKSIARLIESGTPASEIAVLYRVNAQSEIY EEALTEAGIPYQVRGGEGFFNRQEIKQALLALQRAAEREGEDARAEPLPAVVRAVLEPLGLTADEPVGTR ARERWEALRALAELVDDEVARRPQLDFAGLLTELRMRADARHPPVVQGVALASLHAAKGLEWDAVFLVGL ADGTLPISHALAHGADSEAVEEERRLLYVGITRARTHLALSWALARSPGGRQSRKPSRFLNGIAPQTRAE AAPTRSRRNRSAATRCRICNNNLTTPAAVMLRRCETCAADIDEDLLVRLKAWRLDVAKEQKVPAYVVFTD NTLIAIAELRPGDEQALIAIPGIGARKLEQYGPDVLELVRGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4143 | - | - | 100% (743) | ATP-dependent DNA helicase |
| M. avium 104 | MAV_1071 | pcrA | 4e-57 | 35.29% (527) | ATP-dependent DNA helicase PcrA |
| M. avium 104 | MAV_4147 | - | 5e-36 | 30.89% (463) | superfamily protein I DNA and RNA helicases |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3222c | uvrD2 | 0.0 | 84.92% (703) | DNA helicase II |
| M. gilvum PYR-GCK | Mflv_4660 | - | 0.0 | 77.51% (698) | UvrD/REP helicase |
| M. tuberculosis H37Rv | Rv3198c | uvrD2 | 0.0 | 84.92% (703) | ATP-dependent DNA helicase II UVRD2 |
| M. leprae Br4923 | MLBr_00637 | uvrD2 | 0.0 | 81.24% (709) | putative ATP-dependent DNA helicase |
| M. abscessus ATCC 19977 | MAB_3511c | - | 0.0 | 75.71% (700) | DNA helicase II |
| M. marinum M | MMAR_1364 | uvrD2 | 0.0 | 83.68% (711) | ATP-dependent DNA helicase II UvrD2 |
| M. smegmatis MC2 155 | MSMEG_1952 | - | 0.0 | 78.52% (703) | ATP-dependent DNA helicase |
| M. thermoresistible (build 8) | TH_1135 | uvrD2 | 0.0 | 77.68% (717) | PROBABLE ATP-DEPENDENT DNA HELICASE II UVRD2 |
| M. ulcerans Agy99 | MUL_2512 | uvrD2 | 0.0 | 83.88% (701) | ATP-dependent DNA helicase II UvrD2 |
| M. vanbaalenii PYR-1 | Mvan_1807 | - | 0.0 | 77.97% (708) | UvrD/REP helicase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4660|M.gilvum_PYR-GCK ------------------------------------MMVAMSPTAS--RD
Mvan_1807|M.vanbaalenii_PYR-1 ------------------------------------MMEAMSPTAS--RD
TH_1135|M.thermoresistible__bu ------------------------------------MMVAMPAEASSLRA
MSMEG_1952|M.smegmatis_MC2_155 ------------------------------MSGGADIMVGMPLEAP---S
MAB_3511c|M.abscessus_ATCC_199 -------------------------------------------MAR----
Mb3222c|M.bovis_AF2122/97 ----------------------------------------MSIASD----
Rv3198c|M.tuberculosis_H37Rv ----------------------------------------MSIASD----
MLBr_00637|M.leprae_Br4923 -------------------------------------MDPMVMVVN----
MAV_4143|M.avium_104 MVPGDEAFRAAGCAGAGRLAGARCTAFVTDLSVWEAKMDAMPTLAD----
MMAR_1364|M.marinum_M ------------------------------MSARTVKMETMPTLAQ----
MUL_2512|M.ulcerans_Agy99 ----------------------------------------MPTLAQ----
Mflv_4660|M.gilvum_PYR-GCK RLLGDLDDEQREAVLAPRGPVCVLAGAGTGKTRTITRRIAHLVTAGHVAP
Mvan_1807|M.vanbaalenii_PYR-1 RLLGDLDDEQREAVLAPRGPVCVLAGAGTGKTRTITRRIAHLVTAGHVAP
TH_1135|M.thermoresistible__bu RLLDDLDDEQREAVTAPRGPVCVLAGAGTGKTRTITRRIAYLVAAGHVAP
MSMEG_1952|M.smegmatis_MC2_155 PTLEDLDDEQREAVLAPRGPVCVLAGAGTGKTRTITRRIAHLVAGGHVAA
MAB_3511c|M.abscessus_ATCC_199 SLLDGLDDEQRAAVTAPRGPVCVLAGAGTGKTRTITHRIAYLVASGHVAA
Mb3222c|M.bovis_AF2122/97 PLIAGLDDQQREAVLAPRGPVCVLAGAGTGKTRTITHRIASLVASGHVAA
Rv3198c|M.tuberculosis_H37Rv PLIAGLDDQQREAVLAPRGPVCVLAGAGTGKTRTITHRIASLVASGHVAA
MLBr_00637|M.leprae_Br4923 PLTAGLDDEQREAVLAPRGPVCVLAGAGTGKTRTITHRIAHLVGAGHVAT
MAV_4143|M.avium_104 PLTAGLDDEQREAVLAPRGPVCVLAGAGTGKTRTITHRIAQLVAGGHVAA
MMAR_1364|M.marinum_M PLTAGLDDEQREAVLAPRGPVCVLAGAGTGKTRTITHRIAQLVASGHVAA
MUL_2512|M.ulcerans_Agy99 PLTAGLDDEQREAVLAPRGPVCVLAGAGTGKTRTITHRIAQLVASGHVAA
.***:** ** *********************:*** ** .****.
Mflv_4660|M.gilvum_PYR-GCK GQVLAVTFTQRAAGEMRGRLRALD----EGSGTGGVQAQTFHAAARRQLS
Mvan_1807|M.vanbaalenii_PYR-1 GQVLAVTFTQRAAGEMRGRLRALGGDE-AGASTAAVQAQTFHAAARRQLS
TH_1135|M.thermoresistible__bu SQVLAVTFTQRAAGEMRGRLRALD----DGVGTGAVQAMTFHAAARRQLR
MSMEG_1952|M.smegmatis_MC2_155 GQVLAVTFTARAAGEMRARLRALG-QQ-TGVPTGAVQAVTFHAAARRQLQ
MAB_3511c|M.abscessus_ATCC_199 GQILAVTFTQRAAGEMRGRLRDLG--------VGSAQAVTFHAAGLRQLR
Mb3222c|M.bovis_AF2122/97 GQVLAVTFTQRAAGEMRSRLRALDAAARTGSGVGAVQALTFHAAAYRQLR
Rv3198c|M.tuberculosis_H37Rv GQVLAVTFTQRAAGEMRSRLRALDAAARTGSGVGAVQALTFHAAAYRQLR
MLBr_00637|M.leprae_Br4923 GQVLAVTFTQRAAAEMRSRLRALGAAVQAVSDFGVVRVLTFHAAAHRQLR
MAV_4143|M.avium_104 NQVLAVTFTQRAAGEMRSRLRALAAAAGTDAAVGSVSALTFHAAAHRQLR
MMAR_1364|M.marinum_M GQVLAVTFTQRAAGEMRARLRGLDAAAQTSSGVGAVQALTFHAAAHRQLR
MUL_2512|M.ulcerans_Agy99 GQVLAVTFTQRAAGEMRARLRGLDAAAQTSSGVGAVQALTFHAAAHRQLR
.*:****** ***.***.*** * . . . *****. ***
Mflv_4660|M.gilvum_PYR-GCK YFWPRVVGNTEWQLMDSKFAVVAQAANRGGLPTGTDNVRDLAGEIEWAKA
Mvan_1807|M.vanbaalenii_PYR-1 YFWPRVVGTTDWQLMDSKFAVVAQAANRAGLPTGTDNVRDLAGEIEWAKA
TH_1135|M.thermoresistible__bu YFWPQVVGDAPWQLLDSKFSVVASAANRCGLPTGTDDVRDLAGEIEWAKA
MSMEG_1952|M.smegmatis_MC2_155 YFWPRLVGDTGWELLDSKFSVVAQAANRAGLQPSTDDVRDLAGEIEWAKA
MAB_3511c|M.abscessus_ATCC_199 YFWPQLVGDTRWELIDSKFTLVAQAANRAKVSTTTDTVRDLAGEIEWAKA
Mb3222c|M.bovis_AF2122/97 YFWSRVIADTGWQLLDSKFAVVARAASRTRLHASTDDVRDLAGEIEWAKA
Rv3198c|M.tuberculosis_H37Rv YFWSRVIADTGWQLLDSKFAVVARAASRTRLHASTDDVRDLAGEIEWAKA
MLBr_00637|M.leprae_Br4923 YFWPRVIGDTGWQLLDSKFATVARAASSVRLHAGTDDVCDLAGEIEWAKA
MAV_4143|M.avium_104 YFWPRVVGDTGWQLLDSKFAVVARAASRTRINASTDDVRDLAGEIEWAKA
MMAR_1364|M.marinum_M YFWPRVVGDIGWQLLDSKFAVVARAAGRARLNASSDNVRDLAGEIEWAKA
MUL_2512|M.ulcerans_Agy99 YFWPRVVGDIGWQLLDSKFAVVARAAGRARLNASSDNVRDLAGEIEWAKA
***.:::. *:*:****: ** **. : . :* * ***********
Mflv_4660|M.gilvum_PYR-GCK SLISPETYADAVAEVSRDIPFDAAKIATVYANYEALKTRNE---GLVLLD
Mvan_1807|M.vanbaalenii_PYR-1 SLITPEGYPQAVADVGRDIPFDAAKVAAVYGNYESLKSRRN---DVMLLD
TH_1135|M.thermoresistible__bu SLITPEDYPKAVAEAGRDIPFDAAKVAAAYAGYEALKAR-Q---ETVLLD
MSMEG_1952|M.smegmatis_MC2_155 SLITPEAYGAAVAKVGRDIPLDAQKVAAVYSGYEALKARRD---GSALLD
MAB_3511c|M.abscessus_ATCC_199 SLISPETYPAAAAKFGRDAPVPAEQVAKVYAGYEKLKARPD---GSTLLD
Mb3222c|M.bovis_AF2122/97 SLIGPEEYVTAVAAARRDPPLDAAQIAAVYSEYEALKARGD---GVTLLD
Rv3198c|M.tuberculosis_H37Rv SLIGPEEYVTAVAAARRDPPLDAAQIAAVYSEYEALKARGD---GVTLLD
MLBr_00637|M.leprae_Br4923 SLIGPEEYVAAVAAIGRDTPLDAAQIASVYAAYEALKARGNGVPGVTLLD
MAV_4143|M.avium_104 SLIGPEEYPAAVAAAGRDIPLDAARVAGVYAAYEALKARGD---HVTLLD
MMAR_1364|M.marinum_M SLITPEQYPAAVAAASRDTPLDAAQIAAVYAEYESLKVRDE---SLTLLD
MUL_2512|M.ulcerans_Agy99 SLITPEQYPAAVVAASRDTPLDAAQIAAVYAEYESLKVRDE---SLTLLD
*** ** * *.. ** *. * ::* .*. ** ** * : ***
Mflv_4660|M.gilvum_PYR-GCK FDDLLLHTAAAIENDPAVAQEFRDRYRCFVVDEYQDVTPLQQRVLDAWLG
Mvan_1807|M.vanbaalenii_PYR-1 FDDLLLHTAAAIENDPAVAQEFRDRYRCFVVDEYQDVTPLQQRVLDAWLG
TH_1135|M.thermoresistible__bu FDDLLLHTAAAIENEPAVAQEFRDRYRCFVVDEYQDVTPLQQRVLNAWLG
MSMEG_1952|M.smegmatis_MC2_155 FDDLLLHTAAAIENDAAVAQEFRDRYRCFVVDEYQDVTPLQQRVLDAWLG
MAB_3511c|M.abscessus_ATCC_199 FDDLLLHTAAAIENSAAVAEEFRDRYRCFVVDEYQDVTPLQQRVLDAWLG
Mb3222c|M.bovis_AF2122/97 FDDLLLHTAAAIENDAAVAEEFQDRYRCFVVDEYQDVTPLQQRVLSAWLG
Rv3198c|M.tuberculosis_H37Rv FDDLLLHTAAAIENDAAVAEEFQDRYRCFVVDEYQDVTPLQQRVLSAWLG
MLBr_00637|M.leprae_Br4923 FDDLLLHTAAAIENDAAVAEEFRDRYRCFVVDEYQDVTPLQQRVLSAWLG
MAV_4143|M.avium_104 FDDLLLHTAAAIENDPAVAEEFRDRYRCFVVDEYQDVTPLQQRVLAAWLG
MMAR_1364|M.marinum_M FDDLLLHTAAAIENDAAVAQEFRDRYRCFVVDEYQDVTPLQQRVLLAWLG
MUL_2512|M.ulcerans_Agy99 FDDLLLHTAAAIENDAAVAQEFRDRYRCFVVDEYQDVTPLQQRVLLAWLG
**************..***:**:********************** ****
Mflv_4660|M.gilvum_PYR-GCK NRDDLTVVGDANQTIYSFTGASPRYLLDFSRRFPEVTLVRLERDYRSTPQ
Mvan_1807|M.vanbaalenii_PYR-1 GRDDLTVVGDANQTIYSFTGASPRYLLDFSRRFPDAAVVRLERDYRSTPQ
TH_1135|M.thermoresistible__bu ERDDLTVVGDANQTIYSFTGATPQYLLDFSRRFPDATVVRLERDYRSTPQ
MSMEG_1952|M.smegmatis_MC2_155 DRDDLTVVGDANQTIYSFTGATPRYLLDFSRRFPDAAVVRLERDYRSTPQ
MAB_3511c|M.abscessus_ATCC_199 PRDDVTVVGDANQTIYSFTGATPQYLLGFSRRFPDATVVRLERDYRSTPQ
Mb3222c|M.bovis_AF2122/97 DRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDAAVVRLERDYRSTPQ
Rv3198c|M.tuberculosis_H37Rv DRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDAAVVRLERDYRSTPQ
MLBr_00637|M.leprae_Br4923 DRDDLTVVGDANQTIYSFTGASPCFLLDFPRRFPDATVVRLERDYRSTPQ
MAV_4143|M.avium_104 DRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDATVVRLERDYRSTPQ
MMAR_1364|M.marinum_M DRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDATLVRLERDYRSTPQ
MUL_2512|M.ulcerans_Agy99 DRDDLTVVGDANQTIYSFTGASPRFLLDFSRRFPDATLVRLERDYRSTPQ
***:****************:* :**.*.****:.::************
Mflv_4660|M.gilvum_PYR-GCK VVSLANRVIAGARGRMAGSRLHLVGQRPPGPEPVFKEYPDEVAEAAAVAK
Mvan_1807|M.vanbaalenii_PYR-1 VVSLANRVIAAARGRMAGSRLHLVGQRPPGPDPVFKEYPDEVAEATAVAR
TH_1135|M.thermoresistible__bu VVSLANRVIATARGRMAGSKLHLVGQRPPGPQPTFSEYPDEVAEATAVAK
MSMEG_1952|M.smegmatis_MC2_155 VVSLANRVIAGARGRMAGSKLHLVGQRDPGPKPTFNEYPDEVAEAKGVAK
MAB_3511c|M.abscessus_ATCC_199 VVSLANRLISAAQGRVAGSKLQLIGQRPQGPAPRFSEHDDEAAEAKSVAK
Mb3222c|M.bovis_AF2122/97 VVSLANRVIAAARGRVAGSKLRLSGQREPGPVPSFHEHSDEPAEAATVAA
Rv3198c|M.tuberculosis_H37Rv VVSLANRVIAAARGRVAGSKLRLSGQREPGPVPSFHEHSDEPAEAATVAA
MLBr_00637|M.leprae_Br4923 VVSLANQVIAAAHGRVADSKFQLSGQREPGPAASFHEYSDEPAEAAAVAA
MAV_4143|M.avium_104 VVSLANQVIAAARGRVAGSKLHLVGQRPPGPVPTFHEHPDEPAEAAAVAK
MMAR_1364|M.marinum_M VVSLANRVIAAARGRVAGSRLQLTGQREPGPAPSFDEYPDEVAEATAVAA
MUL_2512|M.ulcerans_Agy99 VVSLANRVIAAARGRVAGSRLQLTGQREPGPAPSFDEYPDEVAEATAVAA
******::*: *:**:*.*:::* *** ** . * *: ** *** **
Mflv_4660|M.gilvum_PYR-GCK SIRTLIESGTAASEIAVLYRINAQSEVYEEALTEAGVAFQVRGGEGFFSR
Mvan_1807|M.vanbaalenii_PYR-1 SIAKLVESGTAASEIAVLYRINAQSEVYEEALTEAGIAFQVRGGEGFFSR
TH_1135|M.thermoresistible__bu NIARLIESGVAPAEIAVLYRINAQSEVYEEALTEAGIAFQVRGGEGFFSR
MSMEG_1952|M.smegmatis_MC2_155 AIQKLIEKGTAPAEIAVLYRINAQSEVYEEALTEAGIAFQVRGGEGFFSR
MAB_3511c|M.abscessus_ATCC_199 SIAALIESGTPASEVAVLYRINAQSEVYEEALTEAGIPFQVRGGEGFFTR
Mb3222c|M.bovis_AF2122/97 SIARLIASGTPPSEVAILYRVNAQSEVYEEALTQAGIAYQVRGGEGFFNR
Rv3198c|M.tuberculosis_H37Rv SIARLIASGTPPSEVAILYRVNAQSEVYEEALTQAGIAYQVRGGEGFFNR
MLBr_00637|M.leprae_Br4923 SIARLIEFGTSPSEIAVLYRVNAQSEAYEEALTEVGIAYQVRGGEGFFNR
MAV_4143|M.avium_104 SIARLIESGTPASEIAVLYRVNAQSEIYEEALTEAGIPYQVRGGEGFFNR
MMAR_1364|M.marinum_M SIARLIQSGTPASEIAILYRVNAQSEVYEEALTEAGIAYQVRGGEGFFNR
MUL_2512|M.ulcerans_Agy99 SIARLIQSGTPASEIAILYRVNAQSEVYEEALTEAGIAYQVRGGEGFFNR
* *: *...:*:*:***:***** ******:.*:.:*********.*
Mflv_4660|M.gilvum_PYR-GCK QEIRQALLALQRVAERG-----AGDTGGSLPEIVRAILEPLGLTAEPPAG
Mvan_1807|M.vanbaalenii_PYR-1 QEIRQALLALQRLAERG-----LQDTADSLPEFVRAALEPLGLTAEPPPG
TH_1135|M.thermoresistible__bu QEIRQALLVLQRAAERAGTGAVETPAGAELAAAVRGLLEPLGLTAEPPAG
MSMEG_1952|M.smegmatis_MC2_155 QEIRQALVALQRAAERE-------VEITDLPVFVRELLEPLGLTAEAPAG
MAB_3511c|M.abscessus_ATCC_199 QEVRQALVALQRAAGRE-------DAGMPVPEQVREILEPLGLSQEEPHG
Mb3222c|M.bovis_AF2122/97 QEIKQALLALQRVSER--------DTDAALSDVVRAVLAPLGLTAQPPVG
Rv3198c|M.tuberculosis_H37Rv QEIKQALLALQRVSER--------DTDAALSDVVRAVLAPLGLTAQPPVG
MLBr_00637|M.leprae_Br4923 QEIKQALLALQRSAERSS----QTEPNSPLSDVVRGVLEPLGLTAEKPVG
MAV_4143|M.avium_104 QEIKQALLALQRAAEREG----EDARAEPLPAVVRAVLEPLGLTADEPVG
MMAR_1364|M.marinum_M QEVKQAMVALQRAAER--------DIEAALPDVVRTVLEPLGLTAEEPAG
MUL_2512|M.ulcerans_Agy99 QEVKQAMVALQRAAER--------DIEAALPDVVRTVLEPLGLTAEEPAG
**::**::.*** : * :. ** * ****: : * *
Mflv_4660|M.gilvum_PYR-GCK TRARDRWEALVALAELVDDEVAQRPHLDLRALLTELRQRADSRHPPVVQG
Mvan_1807|M.vanbaalenii_PYR-1 AQARDRWEALVALAELVDDEVAQRPQLDLHGLLAELRQRADSRHPPVVQG
TH_1135|M.thermoresistible__bu TRARERWEALAALADLVDEEVATQPGLTLPGLLNELRRRADARHPPVVQG
MSMEG_1952|M.smegmatis_MC2_155 TRARERWEALVALAELVEEEVALRPELDLRALVGELRQRADARHPPVVQG
MAB_3511c|M.abscessus_ATCC_199 TQARERWESLRALVELADEECARQPELDLPGLVRELRVRAEARHPPTVQG
Mb3222c|M.bovis_AF2122/97 TRARERWEALTALAELVDDELAQRPALQLPGLLAELRRRAEARHPPVVQG
Rv3198c|M.tuberculosis_H37Rv TRARERWEALTALAELVDDELAQRPALQLPGLLAELRRRAEARHPPVVQG
MLBr_00637|M.leprae_Br4923 SRARDRWEALTALAELADDEVAQHPRLDLPGLLAELRLRADARHPPVVQG
MAV_4143|M.avium_104 TRARERWEALRALAELVDDEVARRPQLDFAGLLTELRMRADARHPPVVQG
MMAR_1364|M.marinum_M TRARERWEALSALAQLVDDEVAQRPHLQLAGLLAELRARADARHPPVVQG
MUL_2512|M.ulcerans_Agy99 TRARERWEALSALAQLVDDEVAQRPHLQLAGLLAELRARADARHPPEVQG
::**:***:* **.:*.::* * :* * : .*: *** **::**** ***
Mflv_4660|M.gilvum_PYR-GCK VTLASLHAAKGLEWDAVYLVGLADGTLPISHALSHGPDSEPVEEERRLLY
Mvan_1807|M.vanbaalenii_PYR-1 VTLASLHAAKGLEWDAVFLVGLADGTLPISHALAHGPDSEPVEEERRLLY
TH_1135|M.thermoresistible__bu VTLASLHAAKGLEWDAVFLVGLADGTLPISHALAHGPESEPVEEERRLLY
MSMEG_1952|M.smegmatis_MC2_155 VTLASLHAAKGLEWDAVFLVGLADGTLPISHALSHGPDSEPVEEERRLLY
MAB_3511c|M.abscessus_ATCC_199 VTLASLHAAKGLEWDAVFLVGLADGTLPISHALSRAGDIEPVEEERRLLY
Mb3222c|M.bovis_AF2122/97 VTLASLHAAKGLEWDAVFLVGLADGTLPISHALAHGPNSEPVEEERRLLY
Rv3198c|M.tuberculosis_H37Rv VTLASLHAAKGLEWDAVFLVGLADGTLPISHALAHGPNSEPVEEERRLLY
MLBr_00637|M.leprae_Br4923 VTLASLHAVKGLEWDAVFLVGLADGTLPISRALAHGAESEPVEEERRLLY
MAV_4143|M.avium_104 VALASLHAAKGLEWDAVFLVGLADGTLPISHALAHGADSEAVEEERRLLY
MMAR_1364|M.marinum_M VTLASLHAAKGLEWDAVFLVGLADGTLPISHALAHGPESEQVEEERRLLY
MUL_2512|M.ulcerans_Agy99 VTLASLHAAKGLEWHAVFLVGLADGTLPISHALAHGPESEQVEEERRLLY
*:******.*****.**:************:**::. : * *********
Mflv_4660|M.gilvum_PYR-GCK VGVTRARVHLTLSWALARKPGGRQGRRPSRFLTGIAP--QSQRD-DGPSR
Mvan_1807|M.vanbaalenii_PYR-1 VGVTRARVHLTLSWALARKPGGRQGRRPSRFLNGIAP--QSQRD-DGPSK
TH_1135|M.thermoresistible__bu VGITRARVHLALSWALARAPGGRQGRRPSRFLNGIAPNVGSAGDRSGPTR
MSMEG_1952|M.smegmatis_MC2_155 VGVTRARVHLALSWALARTPGGRQGRRPSRFLNGIAP--QTENSSSGPDR
MAB_3511c|M.abscessus_ATCC_199 VGITRARVHLNLSWALSRAAGGRKSRKHSRFLNGIAP----TAQLPASAT
Mb3222c|M.bovis_AF2122/97 VGITRARVHLALSWALSRSPGGRQSRKPSRFLNGIAP---QTRADPVPGT
Rv3198c|M.tuberculosis_H37Rv VGITRARVHLALSWALSRSPGGRQSRKPSRFLNGIAP---QTRADPVPGT
MLBr_00637|M.leprae_Br4923 VGITRARVYLALSWALSRTPGGRQSRKPSRFLNDIAP---QMGQNPASSR
MAV_4143|M.avium_104 VGITRARTHLALSWALARSPGGRQSRKPSRFLNGIAP---QTRAEAAPTR
MMAR_1364|M.marinum_M VGVTRARVHLALTWALARSPGGRQGRKPSRFLNGIAP---QTRADPGPAK
MUL_2512|M.ulcerans_Agy99 VGVTRARVHLALTWALARSPGGRQGRKPSRFLNGIAP---QTRADPGPAK
**:****.:* *:***:* .***:.*: ****..*** .
Mflv_4660|M.gilvum_PYR-GCK SRKPRGPAPRCRVCNAQLTSPTAIMLRRCESCPSDIDDELLAELKDWRLR
Mvan_1807|M.vanbaalenii_PYR-1 PRKPRGPAPRCRVCNAALTSPPAIMLRRCETCPSDIDEQLLADLKDWRLR
TH_1135|M.thermoresistible__bu PRRQRGATPRCRICNAVLTAPPAIMLRRCESCPADIDEELLAELKEWRSR
MSMEG_1952|M.smegmatis_MC2_155 PRRQRGPAPRCRICNAALSTPQAIMLRRCETCPSNLDEDLLAELKEWRLR
MAB_3511c|M.abscessus_ATCC_199 PRR-RGGGARCRVCNAALSTPAAVLLRRCESCPSDIDEELLVALKDWRLK
Mb3222c|M.bovis_AF2122/97 SRRNRGAAARCRICNNELNTSAAVMLRRCETCAADVDEELLLQLKSWRLS
Rv3198c|M.tuberculosis_H37Rv SRRNRGAAARCRICNNELNTSAAVMLRRCETCAADVDEELLLQLKSWRLS
MLBr_00637|M.leprae_Br4923 SRRNRTATLRCRICKNDLTTPAAVMLQRCQICAADVDEELLLQLKAWRLS
MAV_4143|M.avium_104 SRRNRSAATRCRICNNNLTTPAAVMLRRCETCAADIDEDLLVRLKAWRLD
MMAR_1364|M.marinum_M NRRNR-GPVRCRICNKELTTPAAVMLRRCETCAGDVNEELLLQLKSWRLN
MUL_2512|M.ulcerans_Agy99 NRRNR-GPVRCRICNKELTTPAAVMLRRCETCAGDVNEELLLQLKSWRLN
*: * ***:*: *.:. *::*:**: *..:::::** ** **
Mflv_4660|M.gilvum_PYR-GCK ISKEMSVPAFVVFTDNTLIAIAESMPTDDAGLVAIPGIGARKLEQYGPDV
Mvan_1807|M.vanbaalenii_PYR-1 IAKEMNVPAYVVFTDNTLIAIAESLPSDDAALVAIPGIGARKLEQFGPDV
TH_1135|M.thermoresistible__bu TAKEMSVPAYVVFTDNTLIAIAEMLPTDDAALVAIPGIGARKLEQFGPDV
MSMEG_1952|M.smegmatis_MC2_155 VSKEMKVPAYVVFTDTTLMAIAETLPTDDAALVAIPGIGARKLEQYGEDV
MAB_3511c|M.abscessus_ATCC_199 TAKEMKVPAFVVFTDNTLIAIAELLPGDDAALVAIPGIGARKLEQYGPDV
Mb3222c|M.bovis_AF2122/97 TAKEQNVPAYVVFTDNTLIAIAELLPTDDAALIAIPGIGARKLEQYGSDV
Rv3198c|M.tuberculosis_H37Rv TAKEQNVPAYVVFTDNTLIAIAELLPTDDAALIAIPGIGARKLEQYGSDV
MLBr_00637|M.leprae_Br4923 TAKEQNVPAYVVLTDNTLIAIAELLPADEAALIAVPGMSVRKIEQYGSDV
MAV_4143|M.avium_104 VAKEQKVPAYVVFTDNTLIAIAELRPGDEQALIAIPGIGARKLEQYGPDV
MMAR_1364|M.marinum_M TAKEQNVPAYVVFTDNTLIAIAELLPADDASLIAIPGIGARKLEQYGADV
MUL_2512|M.ulcerans_Agy99 TAKEQNVPAYVVFTDNTLIAIAELRPADDASLIAIPGIGARRLEQYGADV
:** .***:**:**.**:**** * *: .*:*:**:..*::**:* **
Mflv_4660|M.gilvum_PYR-GCK LALVKGRQKS-----
Mvan_1807|M.vanbaalenii_PYR-1 LALVKGRQKS-----
TH_1135|M.thermoresistible__bu LAMVKNRR-------
MSMEG_1952|M.smegmatis_MC2_155 VALVRGRANRHDS--
MAB_3511c|M.abscessus_ATCC_199 LRLVRARSS------
Mb3222c|M.bovis_AF2122/97 LQLVRGRT-------
Rv3198c|M.tuberculosis_H37Rv LQLVRGRT-------
MLBr_00637|M.leprae_Br4923 LQLVRCRAVAVRTQT
MAV_4143|M.avium_104 LELVRGR--------
MMAR_1364|M.marinum_M LELVRQAR-------
MUL_2512|M.ulcerans_Agy99 LELVRQAR-------
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