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MSALVPDLPPHPPAGAAPAGDAVMMLTGERTIPGLDIENYWFRRHEVVYQRLARHCAGRDVLEAGCGEGY GADLIAGVARRVIAVDYDEAAVAHVRGRYPRVDVMQANLAQLPLPDSSVDVVVNFQVIEHLWDQTQFVVE CARVLRPSGLLLMSTPNRITFSPGRDTPINPFHTRELNAVELTELLVGGGFRDVSISGLFHGPRLREMDA RHGGSIIDAQIARAVADAPWPPQLAADVAAVTVDDFELVPSGADAASGHHIDDSLDLIAIAVAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3877 | - | - | 100% (274) | hypothetical protein MAV_3877 |
| M. avium 104 | MAV_4945 | - | 6e-09 | 28.88% (187) | SAM-dependent methyltransferase |
| M. avium 104 | MAV_2111 | - | 1e-07 | 27.81% (151) | methyltransferase, UbiE/COQ5 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3056 | - | 1e-119 | 77.34% (278) | hypothetical protein Mb3056 |
| M. gilvum PYR-GCK | Mflv_4260 | - | 1e-106 | 73.33% (255) | methyltransferase type 11 |
| M. tuberculosis H37Rv | Rv3030 | - | 1e-119 | 77.34% (278) | hypothetical protein Rv3030 |
| M. leprae Br4923 | MLBr_01713 | - | 1e-113 | 72.66% (278) | hypothetical protein MLBr_01713 |
| M. abscessus ATCC 19977 | MAB_3364 | - | 1e-102 | 66.79% (271) | hypothetical protein MAB_3364 |
| M. marinum M | MMAR_1683 | - | 1e-120 | 77.21% (272) | hypothetical protein MMAR_1683 |
| M. smegmatis MC2 155 | MSMEG_2350 | - | 1e-107 | 73.66% (262) | hypothetical protein MSMEG_2350 |
| M. thermoresistible (build 8) | TH_2193 | - | 1e-105 | 71.37% (255) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1921 | - | 1e-120 | 77.21% (272) | hypothetical protein MUL_1921 |
| M. vanbaalenii PYR-1 | Mvan_2098 | - | 1e-106 | 70.80% (274) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2350|M.smegmatis_MC2_155 ------MGDPDNALPS----------ALPLTGERTIPGLAEENYWFRRHE
TH_2193|M.thermoresistible__bu MSAFSTAGSDADGPIS----------VLPLTGERTVPGLERENYWFRRHE
Mflv_4260|M.gilvum_PYR-GCK MSASVTNG---DPG-------------LPLTGERTIPGLAEENYWFRRHE
Mvan_2098|M.vanbaalenii_PYR-1 MSASVTDGPTEDPAP------------MALTGERTVPGVAEENYWFRRHE
MAB_3364|M.abscessus_ATCC_1997 MNSHLTDPHPADPLRTSGPSAEDPDATLALTGERTVPGIAEENYWFRRHE
Mb3056|M.bovis_AF2122/97 MCAFVPHVPRHSRGDNPPSASTASPAVLTLTGERTIPDLDIENYWFRRHQ
Rv3030|M.tuberculosis_H37Rv MCAFVPHVPRHSRGDNPPSASTASPAVLTLTGERTIPDLDIENYWFRRHQ
MLBr_01713|M.leprae_Br4923 MSAFVPDVPNRIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRRHQ
MMAR_1683|M.marinum_M MSSFVPDVPDQIP----TASAPPVDAVLTLTGERTIPDLDIENYWFRRHE
MUL_1921|M.ulcerans_Agy99 MSSFVPDVPDQIP----TASAPPVDAVLTLTGERTIPDLDIENYWFRRHE
MAV_3877|M.avium_104 MSALVPDLPPHPP----AGAAPAGDAVMMLTGERTIPGLDIENYWFRRHE
: ******:*.: ********:
MSMEG_2350|M.smegmatis_MC2_155 VVYQRLAHRCAGRDVLEAGCGEGYGADLIADVARRVIGLDYDEATVAHVR
TH_2193|M.thermoresistible__bu VVYQRLAHRCAGRVVLEAGCGEGYGADLLAEVAAHVIGLDYDAATVAHVR
Mflv_4260|M.gilvum_PYR-GCK VVYRRLVERCRDRDVLEAGSGEGYGADLIAEVARSVIGLDYDESAVAHVR
Mvan_2098|M.vanbaalenii_PYR-1 VVYRRLVDRCAGRDVLEAGCGEGYGAALIAEVARSVIGLDYDESAVAHVR
MAB_3364|M.abscessus_ATCC_1997 VVYERLSSLCAGRRVLEAGSGEGYGADMLAQVAQHVIGLDYDESAIAHVK
Mb3056|M.bovis_AF2122/97 VVYQRLAPRCTARDVLEAGCGEGYGADLIACVARQVIAVDYDETAVAHVR
Rv3030|M.tuberculosis_H37Rv VVYQRLAPRCTARDVLEAGCGEGYGADLIACVARQVIAVDYDETAVAHVR
MLBr_01713|M.leprae_Br4923 VVYQWLAQRCTGCEVLEAGCGEGYGADLIVDVAYRVIAVDYDEATVAHVR
MMAR_1683|M.marinum_M VVYERLAPRCEGRDVLEAGCGEGYGADMIADVARRVVAVDYDEAAVAHVR
MUL_1921|M.ulcerans_Agy99 VVYERLAPRCEGRDVLEAGCGEGYGADMIADVARRVVAVDYDEAAVAHVR
MAV_3877|M.avium_104 VVYQRLARHCAGRDVLEAGCGEGYGADLIAGVARRVIAVDYDEAAVAHVR
***. * * *****.****** ::. ** *:.:*** :::***:
MSMEG_2350|M.smegmatis_MC2_155 ARYPRVDIRHGNLAELPLPDASVDVVVNFQVIEHLWDQAQFVSECFRVLR
TH_2193|M.thermoresistible__bu ARYPRVDIRHGNLVDLPLADASVDVVVNFQVIEHLWDQEKFIAECLRVLR
Mflv_4260|M.gilvum_PYR-GCK ARYPRVDMRHGNLAELPLESGSVDVVVNFQVIEHLWDQGQFVAECARVLR
Mvan_2098|M.vanbaalenii_PYR-1 ARYPRVDMRHGNLAALPLPTASVDVVVNFQVIEHLWDQGQFVAECARVLR
MAB_3364|M.abscessus_ATCC_1997 ARYPRVDMRAGNLADLPLADGSVDVVVNFQVIEHLWDQGQFIRECARVLR
Mb3056|M.bovis_AF2122/97 SRYPRVEVMQANLAELPLPDASVDVVVNFQVIEHLWDQARFVRECARVLR
Rv3030|M.tuberculosis_H37Rv SRYPRVEVMQANLAELPLPDASVDVVVNFQVIEHLWDQARFVRECARVLR
MLBr_01713|M.leprae_Br4923 SRYPRVQVMQANLIELPLADASVDVVVNFQVIEHLWNQAQFVSECARVLR
MMAR_1683|M.marinum_M HRYPRVEVMQANLADLPLPDASMDVVVNFQVIEHLWDQGQFVRECARVLR
MUL_1921|M.ulcerans_Agy99 HRYPRVEVMQANLADLPLPDASMDVVVNFQVIEHLWDQGQFVRECARVLR
MAV_3877|M.avium_104 GRYPRVDVMQANLAQLPLPDSSVDVVVNFQVIEHLWDQTQFVVECARVLR
*****:: .** *** .*:*************:* :*: ** ****
MSMEG_2350|M.smegmatis_MC2_155 PGGVFLVSTPNRITFSPGRDTPLNPFHTRELNAAELTELLETAGFEVEDT
TH_2193|M.thermoresistible__bu PGGQLLVSTPNRITFTPGSDTPVNPFHTRELNAAELTELLTDGGFGLSAM
Mflv_4260|M.gilvum_PYR-GCK PGGVLLMSTPNRITFSPGLDAPVNPFHTRELDAAELTELIESAGFAMETM
Mvan_2098|M.vanbaalenii_PYR-1 PGGVLLMSTPNRITFSPGRDTPVNPFHTRELNAAELTELIESADFAMEAM
MAB_3364|M.abscessus_ATCC_1997 PGGSLLISTPNRITFSPGRDTPLNPFHTRELNGAELTELLEENGFSLESM
Mb3056|M.bovis_AF2122/97 GSGLLMVSTPNRITFSPGRDTPINPFHTRELNADELTSLLIDAGFVDVAM
Rv3030|M.tuberculosis_H37Rv GSGLLMVSTPNRITFSPGRDTPINPFHTRELNADELTSLLIDAGFVDVAM
MLBr_01713|M.leprae_Br4923 PSGLLMVSTPNRITFSPGRDTSINPFHTRELNADELTQLLITADFSEVAM
MMAR_1683|M.marinum_M PSGVLMVSTPNRITFSPGRDTPINPFHTRELNAAELTELLLEAGFAEVTM
MUL_1921|M.ulcerans_Agy99 PSGVLMVSTPNRITFSPGRDTPINPFHTRELNAAELTELLLEAGFAEVTM
MAV_3877|M.avium_104 PSGLLLMSTPNRITFSPGRDTPINPFHTRELNAVELTELLVGGGFRDVSI
.* :::********:** *:.:********:. ***.*: .*
MSMEG_2350|M.smegmatis_MC2_155 LGVFHGAGLAELDARHGGSIIEAQVQRAVADAPWDEQLLADVAAVRTDDF
TH_2193|M.thermoresistible__bu YGVFHGPRLAELDARHGGSIIDAQISRALADEPWPAELLADVASVRTEDF
Mflv_4260|M.gilvum_PYR-GCK LGVFHGPPLVELDARHGGSIIEAQIARAVADAPWPPDLLADVESVTIDHF
Mvan_2098|M.vanbaalenii_PYR-1 LGVFHGRRLAEIDARHGGSVIDAQIARALADAPWPAELLADIESVTIEDF
MAB_3364|M.abscessus_ATCC_1997 NGVFHGPRLRELDAKYGGSIIDAQIERAVAGAPWPQELLADITGLTTEDF
Mb3056|M.bovis_AF2122/97 CGLFHGPRLRDMDARHGGSIIDAQIMRAVAGAPWPPELAADVAAVTTADF
Rv3030|M.tuberculosis_H37Rv CGLFHGPRLRDMDARHGGSIIDAQIMRAVAGAPWPPELAADVAAVTTADF
MLBr_01713|M.leprae_Br4923 YGLFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVADVAAVTAADF
MMAR_1683|M.marinum_M YGLFHGPQLRAIDERHGGSIIDAQIARAVADQPWSAELTADVAAVTTADF
MUL_1921|M.ulcerans_Agy99 YGLFHGPQLRAIDERHGGSIIDAQIARAVADQPWSAELTADVAAVTTADF
MAV_3877|M.avium_104 SGLFHGPRLREMDARHGGSIIDAQIARAVADAPWPPQLAADVAAVTVDDF
*:*** * :* ::***:*:**: **::. ** :* **: .: .*
MSMEG_2350|M.smegmatis_MC2_155 DLTPAAERD-------IDDSLDLVAIAVRP
TH_2193|M.thermoresistible__bu DLIRCDEDDRDRDGHNIDDSLDLVAIAVRP
Mflv_4260|M.gilvum_PYR-GCK DLTAGSDTTP---GRHIDDSLDLVAIAVRP
Mvan_2098|M.vanbaalenii_PYR-1 DLVPADGTH-----RDIDDSLDLVAIAVRT
MAB_3364|M.abscessus_ATCC_1997 EIVDAGERD-------IDASLDLVAIAVIP
Mb3056|M.bovis_AF2122/97 EMVAAG------HDRDIDDSLDLIAIAVRP
Rv3030|M.tuberculosis_H37Rv EMVAAG------HDRDIDDSLDLIAIAVRP
MLBr_01713|M.leprae_Br4923 DIIEASAGPEASDGRDVDESLDLIAIAVRR
MMAR_1683|M.marinum_M DIIGAG----LEPAHEIDDSLDLIAIAVRH
MUL_1921|M.ulcerans_Agy99 DIIGAG----LEPAHEIDDSLDLIAIAVRH
MAV_3877|M.avium_104 ELVPSG--ADAASGHHIDDSLDLIAIAVAP
:: :* ****:****