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DTTDDTIRIRFATEDDWQAVYANQAGAYGVSVDPADVEAWKRRVDLEDILVAEDVSDPARPTVVGTSLCY KLRLTVPGGATLKAAWLAMIAVAATHLGRGVWQQLSIRGFGILQERNYPILCGVPTQPTVYEILGAGVAS YARTYNIEPRFTDLRAKPERNRARVVEADEARGLLPDLYDRWCAVTPGALSRSRAWWADVLEDRVTQRDN GSTLNYVVHPDGFMTYRVIGASPHAFRRPFGNLIVQDFCPITPEAHTDLLATLLSLKMFDNSVIETPVDD PLPLKLKDQLAAQTTKVNDFLWMRIMNVPEVLPKRAYRADADLVLDVTDPLGVAGGRFLLRIRDGVGTCT PHDGPADIKIGLGDLGSIYMGAHRAWELHQADRITELRSGALLDLDAAFTTQRAPYCGTLF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3701 | - | - | 100% (412) | hypothetical protein MAV_3701 |
| M. avium 104 | MAV_1658 | - | e-156 | 63.99% (411) | hypothetical protein MAV_1658 |
| M. avium 104 | MAV_0144 | - | 2e-29 | 29.21% (356) | hypothetical protein MAV_0144 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2439c | - | 3e-50 | 32.67% (404) | hypothetical protein Mb2439c |
| M. gilvum PYR-GCK | Mflv_0866 | - | 1e-57 | 36.59% (399) | hypothetical protein Mflv_0866 |
| M. tuberculosis H37Rv | Rv2416c | eis | 9e-51 | 32.92% (404) | hypothetical protein Rv2416c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4124 | - | 5e-28 | 29.69% (357) | hypothetical protein MAB_4124 |
| M. marinum M | MMAR_3740 | eis | 7e-49 | 30.90% (398) | enhanced intracellular survival protein Eis |
| M. smegmatis MC2 155 | MSMEG_3513 | - | 1e-57 | 37.08% (391) | hypothetical protein MSMEG_3513 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_6041 | - | 5e-52 | 35.34% (382) | hypothetical protein Mvan_6041 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2439c|M.bovis_AF2122/97 -MPQSDSVTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLV--P
Rv2416c|M.tuberculosis_H37Rv -------MTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLV--P
MMAR_3740|M.marinum_M -MTAVLPASVTLTTPAEDDWAGMYLLAAASFTDFIGAESADAWRGLI--P
MSMEG_3513|M.smegmatis_MC2_155 -----MITPRTLHTITDDDWTRIALLARFAFGDIEPEQTQAAWRSMV--P
Mflv_0866|M.gilvum_PYR-GCK --MPAHTTSLTVRSATETDWPAIGLIAATGFGVWRPDETVQVWRSMM--P
Mvan_6041|M.vanbaalenii_PYR-1 ----------------------MALIAATGFGVWTQQETAEAWRSLI--P
MAV_3701|M.avium_104 --MDTTDDTIRIRFATEDDWQAVYANQAGAYGVSVDPADVEAWKRRV--D
MAB_4124|M.abscessus_ATCC_1997 MAFTAQPQWPGASRRNNTGQEAVTDIRFLQSRAEHERAFTVFWRAMVGLP
: *: :
Mb2439c|M.bovis_AF2122/97 TDGAVVVRDGAG--------PGSEVVGMALYMDLRLAVPGEVVLPTAGLS
Rv2416c|M.tuberculosis_H37Rv TDGAVVVRDGAG--------PGSEVVGMALYMDLRLTVPGEVVLPTAGLS
MMAR_3740|M.marinum_M ADGAVVARHGR------------DVVGMALFIDLQLTVPGGNVLSTAGMS
MSMEG_3513|M.smegmatis_MC2_155 EDATVVVPDET----------DDAFVGQSLYLDMQLTVPGGEVLPVAGIS
Mflv_0866|M.gilvum_PYR-GCK PDSVVVACDGD------------EVVGVALFLDLQLTVPGGAVLPMAGVS
Mvan_6041|M.vanbaalenii_PYR-1 AGGAVVACDGP------------DVVGVAVFLDLELTVPGGAVLPMAGVS
MAV_3701|M.avium_104 LEDILVAEDVSDP-------ARPTVVGTSLCYKLRLTVPGGATLKAAWLA
MAB_4124|M.abscessus_ATCC_1997 ALGAVAADELLELGRYLGAFVQGELIGGADSYTSWLTVPGGSRVPHAAVT
:.. . .:* : *:*** : * ::
Mb2439c|M.bovis_AF2122/97 FVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGP
Rv2416c|M.tuberculosis_H37Rv FVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHASEGGIYGRFGYGP
MMAR_3740|M.marinum_M FVAVAPTHRRRGLLRAMCGELHRRMADSGYAMAALHASEGGIYGRFGYGP
MSMEG_3513|M.smegmatis_MC2_155 FVAVAPTHRRRGVLRAMYTELHDRIARAGYPLAVLTASEGGIYGRFGYGV
Mflv_0866|M.gilvum_PYR-GCK FVAVAPTHRRRGALTAMFNELHSRMGD--YPIAGLEASEAGIYGRFGYGP
Mvan_6041|M.vanbaalenii_PYR-1 WVAVAPTHRRRGALSGMFAELHRRMDR--YPIAGLEASEAEIYGRFGYGP
MAV_3701|M.avium_104 MIAVAATHLGRGVWQQLSIRGFGILQERNYPILCGVPTQPTVYEILGAGV
MAB_4124|M.abscessus_ATCC_1997 HIGVLPTHTRRGILTALVTRQLTDIAGRGEIVASLRASEAVIYRRFGYGI
:.* .** ** : . : : .:: :* :* *
Mb2439c|M.bovis_AF2122/97 ATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWR
Rv2416c|M.tuberculosis_H37Rv ATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYERWR
MMAR_3740|M.marinum_M ATILQQLTVDRRFARLHAGVPDGGP----VRLVSPARHRAEFEAIYERWR
MSMEG_3513|M.smegmatis_MC2_155 ATIEQHVSVDRRLAQFHPAAPDPGG----VRMLVPADHRDGLADIYDRWR
Mflv_0866|M.gilvum_PYR-GCK ATVWENVSVERERAQLRAGVPDPGG----VRIVRPAEHRAQLEDIDERWR
Mvan_6041|M.vanbaalenii_PYR-1 ATIWQRLSVDRVAARFHPGVPDPGG----VRVVRAAEHRGQIEDVYERWR
MAV_3701|M.avium_104 ASYARTYNIEPRFTDLRAKPERNRA-----RVVEADEARGLLPDLYDRWC
MAB_4124|M.abscessus_ATCC_1997 ATSSATYRIQRRRAAPLRPIDTGAI-----ALLDAAASPEGLAAIYER--
*: :: : :: . : : :*
Mb2439c|M.bovis_AF2122/97 QQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDR---
Rv2416c|M.tuberculosis_H37Rv QQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDR---
MMAR_3740|M.marinum_M QRVPGGLVRPPVFWDQLMAECKASPGGERESFALLHADGYALYRADR---
MSMEG_3513|M.smegmatis_MC2_155 RRTPGGLVRPDALWDDLLADRPESRRGGGELFAFGHQDGYALYRVDRGP-
Mflv_0866|M.gilvum_PYR-GCK LQTPGGLRTPARLWDEILEDRESLRGGGSALYCLLHGDGFAMYRVHNSE-
Mvan_6041|M.vanbaalenii_PYR-1 LQTPGGLHTPQVLWDEVFADRESHRDGGSAQFCLLHADGFAMYRVHSAD-
MAV_3701|M.avium_104 AVTPGALSRSRAWWADVLEDRVTQRDNGSTLNYVVHPDGFMTYRVIGASP
MAB_4124|M.abscessus_ATCC_1997 AAWTGSVARPPQWWRLHELFDAADP---VKPYVVTHPDGYVRYRPQDTAE
.*.: . * . * **: **
Mb2439c|M.bovis_AF2122/97 ----TDLKLARVSELRAVTADAHCALWRALIGLDSMERISIIT-HPQDPL
Rv2416c|M.tuberculosis_H37Rv ----TDLKLARVSELRAVTADAHCALWRALIGLDSMERISIIT-HPQDPL
MMAR_3740|M.marinum_M ----SDPKLTRVDELRAVTPEARAALWRTLFGLDSMERVSIVS-HPAEPM
MSMEG_3513|M.smegmatis_MC2_155 ----DGRRSAHVVELTAVTADAHAALWRALLGLDLIDRVSIGT-HPHDPL
Mflv_0866|M.gilvum_PYR-GCK ----RRKDRAQVTKLAAATPQAYIALWRTLLGLDLMATVDITT-HPGALL
Mvan_6041|M.vanbaalenii_PYR-1 ----K-KDRVEVSKLAAVTPHAYIALWRALLGLDLMATVDIDT-HPDNTL
MAV_3701|M.avium_104 HAFRRPFGNLIVQDFCPITPEAHTDLLATLLSLKMFDNSVIET-PVDDPL
MAB_4124|M.abscessus_ATCC_1997 WFS-SSARTISVDDLVAHSDEAYRALVGHLLDLDLVDVIELGPRPIDDPL
* .: . : .* * *:.*. . : . :
Mb2439c|M.bovis_AF2122/97 PHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSD
Rv2416c|M.tuberculosis_H37Rv PHLLTDTRLARTTWRQDGLWLRIMNVPAALEARGYAHEVGEFSTVLEVSD
MMAR_3740|M.marinum_M PFLLTNTRLARTTWRQDGLWLRIMDVVPALEARAY---FGDLTTVIAITG
MSMEG_3513|M.smegmatis_MC2_155 PYLLTDPRQAQVTASADDLWIRIMNVPAALEARRY---QADLDVVLDVAD
Mflv_0866|M.gilvum_PYR-GCK PYLLTDARLVRTVDVQDGLWLRMLDIPAVLQARTY---DADLSVALDVSD
Mvan_6041|M.vanbaalenii_PYR-1 PYLLTDPRLVRHPGRQDGLWLRMLDIPAVLQARSY---AADLSVVLEVSD
MAV_3701|M.avium_104 PLKLKDQLAAQTTKVNDFLWMRIMNVPEVLPKRAY---RADADLVLDVTD
MAB_4124|M.abscessus_ATCC_1997 PHLVTDPRAVAVAGIRDETWLRLVDVEAALAARTY---TDGAPVVIEVQD
* :.: . * *:*:::: .* * * .: : .
Mb2439c|M.bovis_AF2122/97 -----GGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLA
Rv2416c|M.tuberculosis_H37Rv -----GGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLYLGAHRASTLA
MMAR_3740|M.marinum_M -----GGRFALQIRDGRAACTPTDAPADVEMDRDVLGSLYLGAHRASTLA
MSMEG_3513|M.smegmatis_MC2_155 GFRSDGGRFALQISGGRARCTTTDAPADIEIDLDVLGGLYLGAHRVDGFA
Mflv_0866|M.gilvum_PYR-GCK PVLDGGGRFAVEIRGGRASCVATDAPADVHTDLSVLGSLYLGAHRASAFA
Mvan_6041|M.vanbaalenii_PYR-1 DILGGGGRFALQVRDGRARCAPTDAEADVHLDLSVLGSLYLGAHRASPFA
MAV_3701|M.avium_104 PLGVAGGRFLLRIRDGVGTCTPHDGPADIKIGLGDLGSIYMGAHRAWELH
MAB_4124|M.abscessus_ATCC_1997 TLLP---HNAARFSVSSDKVRRTQHTPDISVDVAALGSVYLGGNTWTRLE
: .. . : .:: . **.:*:*.: :
Mb2439c|M.bovis_AF2122/97 AANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
Rv2416c|M.tuberculosis_H37Rv AANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
MMAR_3740|M.marinum_M AANRLQAKDVGVIARLDAAFSSEVPAETAFEF
MSMEG_3513|M.smegmatis_MC2_155 AANRLRSKDSELLQQFGAAFAGDMPAELGYGF
Mflv_0866|M.gilvum_PYR-GCK AAHRLRCEDSTQLRALDAAFATDIPAELGYGF
Mvan_6041|M.vanbaalenii_PYR-1 AAHRLRCS-AERARQLDAAFATDGPAELGYGF
MAV_3701|M.avium_104 QADRITELRSGALLDLDAAFTTQRAPYCGTLF
MAB_4124|M.abscessus_ATCC_1997 RAGLVSAQSPGAIRAADALFSTGTQPFAGTNF
* : .* *: . *