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EVPYAPRLVAGAWVVAGWVALAYGIYLTVLALRSPPGVELTGHWVLQPAFKASMALLLTLAAAGHGQVRE RRWLMPALLLSAVGDWVLALPWWTLSFLVGLAAFLFAHMCFIGVLLPLVPLPSGASGPGRPSTPRIAAAV LMCLASIGLLVWFWPRLGPDKLTLPVTLYIVVLTAMVCAALLAKLPTIWTAVGAVCFAASDSMIAIGRFI LGNEALAVPIWWAYAAAQILITAGFFFGREAAGDAAGEATGDAIGDAVEPVE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3376 | - | - | 100% (263) | hypothetical protein MAV_3376 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1436 | - | 5e-82 | 72.28% (202) | hypothetical protein Mb1436 |
| M. gilvum PYR-GCK | Mflv_3734 | - | 6e-70 | 57.08% (233) | YhhN family protein |
| M. tuberculosis H37Rv | Rv1401 | - | 6e-82 | 72.28% (202) | hypothetical protein Rv1401 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4509c | - | 5e-05 | 24.03% (233) | hypothetical protein MAB_4509c |
| M. marinum M | MMAR_2210 | - | 2e-96 | 66.67% (243) | membrane protein |
| M. smegmatis MC2 155 | MSMEG_3060 | - | 6e-66 | 55.51% (227) | hypothetical protein MSMEG_3060 |
| M. thermoresistible (build 8) | TH_1437 | - | 9e-74 | 60.96% (228) | POSSIBLE MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_1796 | - | 1e-100 | 65.48% (252) | membrane protein |
| M. vanbaalenii PYR-1 | Mvan_2683 | - | 1e-72 | 58.26% (242) | YhhN family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1436|M.bovis_AF2122/97 --------------------------------------------------
Rv1401|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2210|M.marinum_M --------------------------------------------------
MUL_1796|M.ulcerans_Agy99 --------------------------------------------------
MAV_3376|M.avium_104 --------------------------------------------------
Mflv_3734|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2683|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3060|M.smegmatis_MC2_155 --------------------------------------------------
TH_1437|M.thermoresistible__bu --------------------------------------------------
MAB_4509c|M.abscessus_ATCC_199 MFTSHRTASTLRGMSDPQLQQMTATLDELDGRERALRAEVDALRGRMVEW
Mb1436|M.bovis_AF2122/97 --------------------------------------------------
Rv1401|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2210|M.marinum_M --------------------------------------------------
MUL_1796|M.ulcerans_Agy99 ------------------------------------MGSIAGFSSAVLSK
MAV_3376|M.avium_104 --------------------------------------------------
Mflv_3734|M.gilvum_PYR-GCK ------------------------------------------------MT
Mvan_2683|M.vanbaalenii_PYR-1 ------------------------------------------------MT
MSMEG_3060|M.smegmatis_MC2_155 --------------------------------------------------
TH_1437|M.thermoresistible__bu --------------------------------------------------
MAB_4509c|M.abscessus_ATCC_199 TQAEYLKAQRYWDDYRRAQGVAQAVAPAPVVMPPARMPVPARAPHPAPPQ
Mb1436|M.bovis_AF2122/97 --------------------------------------------------
Rv1401|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2210|M.marinum_M -----------MTGGWVLAGWAGLGYGVYLTIIAMRR---------PQGM
MUL_1796|M.ulcerans_Agy99 LGMDVPYAPRLVTGGWVLAGWAGLGYGVYLTIIAMRR---------PQGM
MAV_3376|M.avium_104 --MEVPYAPRLVAGAWVVAGWVALAYGIYLTVLALRS---------PPGV
Mflv_3734|M.gilvum_PYR-GCK ------------RTLWISAAVVAAAYGVFLIVTATQV---------HAGA
Mvan_2683|M.vanbaalenii_PYR-1 TVDRRDAPRLRGRALWTAAAVVAAGYGVFLIITATRL---------PAGA
MSMEG_3060|M.smegmatis_MC2_155 --------------MWGAAAVVGAGYGVFLSVTALRL---------PAGA
TH_1437|M.thermoresistible__bu ----------------VAALAAGVAYGLFLIVTALRV---------PAGA
MAB_4509c|M.abscessus_ATCC_199 LEPWWMREGFASKAMALAGAVVTLAGVVMLLVLAAKSGYFGPVPRMVSGA
Mb1436|M.bovis_AF2122/97 ------------------------------------------MLQPAFKA
Rv1401|M.tuberculosis_H37Rv ------------------------------------------MLQPAFKA
MMAR_2210|M.marinum_M ELTG------------------------------------HWILQPPFKA
MUL_1796|M.ulcerans_Agy99 ELTG------------------------------------HWILQPPFKA
MAV_3376|M.avium_104 ELTG------------------------------------HWVLQPAFKA
Mflv_3734|M.gilvum_PYR-GCK ELTG------------------------------------RFVLQPAVKA
Mvan_2683|M.vanbaalenii_PYR-1 ELTG------------------------------------QFVLQPAVKA
MSMEG_3060|M.smegmatis_MC2_155 ALTS------------------------------------QFAAQPAVKA
TH_1437|M.thermoresistible__bu ELTG------------------------------------QFVLQPAVKA
MAB_4509c|M.abscessus_ATCC_199 ALAGGLVALGIRVYSRPGGRVGGIATAATGFAAAFFDVLALTVIYDRIPV
. .
Mb1436|M.bovis_AF2122/97 SMAVLLAAAAVAHPIGRERRWLVPALLLSATGDWLLAIPWWTWAFVFGLG
Rv1401|M.tuberculosis_H37Rv SMAVLLAAAAVAHPIGRERRWLVPALLLSATGDWLLAIPWWTWAFVFGLG
MMAR_2210|M.marinum_M SMAVLLALAAAAHPIARERRWLIAALLFSAAGDWLLAIPWWTQSFVLGLG
MUL_1796|M.ulcerans_Agy99 SMAVLLALAAAAHAIARERRWLIAALLFSAAGDWLLAIPWWTQSFVLGLG
MAV_3376|M.avium_104 SMALLLTLAAAGHGQVRERRWLMPALLLSAVGDWVLALPWWTLSFLVGLA
Mflv_3734|M.gilvum_PYR-GCK LAAVLLAGAALTHGVVRERVWLVGALLFSAAGDYLLAMPWWEPSFVLGLA
Mvan_2683|M.vanbaalenii_PYR-1 LAAVLLAGAALTHRIGRERRWLVGALLFSAAGDYLLAMPWWEPSFVLGLA
MSMEG_3060|M.smegmatis_MC2_155 LAAVLLAAAACTHPIRRERRWLVAALLFSAVGDFLLAIPWWEPSFVGGLA
TH_1437|M.thermoresistible__bu LTAVLLAVAACWHPVPRERRRLIAALVFSAAGDFLLALPWWEMSFLLGLS
MAB_4509c|M.abscessus_ATCC_199 VAGLVLGLGIAGVGLVLARHWNSQPFASGVVAAITVLAPFLTDGFTVELA
.::* . * .: .... : *: .* *.
Mb1436|M.bovis_AF2122/97 AFLLAHLCF-----------------------------------------
Rv1401|M.tuberculosis_H37Rv AFLLAHLCF-----------------------------------------
MMAR_2210|M.marinum_M SFLLAHLCF-----------------------------------------
MUL_1796|M.ulcerans_Agy99 SFLLAHLCF-----------------------------------------
MAV_3376|M.avium_104 AFLFAHMCF-----------------------------------------
Mflv_3734|M.gilvum_PYR-GCK AFLVAHLCF-----------------------------------------
Mvan_2683|M.vanbaalenii_PYR-1 AFLVAHLCF-----------------------------------------
MSMEG_3060|M.smegmatis_MC2_155 AFLVAHLCF-----------------------------------------
TH_1437|M.thermoresistible__bu AFLIAHLFF-----------------------------------------
MAB_4509c|M.abscessus_ATCC_199 AFALILLIASLTAQVGRNWPVLHAFRTVGVSLTLLTAIHVSYTASLALLA
:* . :
Mb1436|M.bovis_AF2122/97 ------------------------------------------------IG
Rv1401|M.tuberculosis_H37Rv ------------------------------------------------IG
MMAR_2210|M.marinum_M ------------------------------------------------LG
MUL_1796|M.ulcerans_Agy99 ------------------------------------------------LG
MAV_3376|M.avium_104 ------------------------------------------------IG
Mflv_3734|M.gilvum_PYR-GCK ------------------------------------------------LA
Mvan_2683|M.vanbaalenii_PYR-1 ------------------------------------------------LA
MSMEG_3060|M.smegmatis_MC2_155 ------------------------------------------------LA
TH_1437|M.thermoresistible__bu ------------------------------------------------LA
MAB_4509c|M.abscessus_ATCC_199 MSVMALLVTLVGSLWLLTGEHDDITSSVMIAVASSPVLYGALFFPVWPLG
:.
Mb1436|M.bovis_AF2122/97 ALLPLA-----------RQAAPSRGRVAAVVAMCVASAG-----------
Rv1401|M.tuberculosis_H37Rv ALLPLA-----------RQAAPSRGRVAAVVAMCVASAG-----------
MMAR_2210|M.marinum_M AMLPMA-----------WGAVPSRPRIAAAALMCVVSVG-----------
MUL_1796|M.ulcerans_Agy99 AMLPMA-----------WGAVPSRPRIAAAALMCVVSVG-----------
MAV_3376|M.avium_104 VLLPLVPLPSG----ASGPGRPSTPRIAAAVLMCLASIG-----------
Mflv_3734|M.gilvum_PYR-GCK ALLPLA--------------RRTPVRVAAVIVTVLACAA-----------
Mvan_2683|M.vanbaalenii_PYR-1 ALLPLA--------------VSSPPRLAAAGAVVAACAA-----------
MSMEG_3060|M.smegmatis_MC2_155 ALLPLA--------------RRTSGRLTAVAVTVVACLA-----------
TH_1437|M.thermoresistible__bu ALIPLV--------------RRSTGRLVAAGVVVAACLG-----------
MAB_4509c|M.abscessus_ATCC_199 VLVPVGVAVVMGAVLLLVGALPVHARITVAAVAGVALLQASVDGARDALL
.::*: *:... .
Mb1436|M.bovis_AF2122/97 -------------------------------------LLVWFWPHLGKD-
Rv1401|M.tuberculosis_H37Rv -------------------------------------LLVWFWPHLGKD-
MMAR_2210|M.marinum_M -------------------------------------LLIWFWPHLGQE-
MUL_1796|M.ulcerans_Agy99 -------------------------------------LLIWFWPHLGQE-
MAV_3376|M.avium_104 -------------------------------------LLVWFWPRLGPD-
Mflv_3734|M.gilvum_PYR-GCK -------------------------------------LLVWFWPRLLEQ-
Mvan_2683|M.vanbaalenii_PYR-1 -------------------------------------LLVWFWPRLLEQ-
MSMEG_3060|M.smegmatis_MC2_155 -------------------------------------LLAWFWPRLVEQ-
TH_1437|M.thermoresistible__bu -------------------------------------LLVWFWPQLLAE-
MAB_4509c|M.abscessus_ATCC_199 AVVLLAIALSCCAIGYQLRDRVALVLGQVFGGLGAAVYLAYVRPELLTDS
* :. *.* :
Mb1436|M.bovis_AF2122/97 --------NLTIPVTVYIVALSAMVCT----------------ALLARLP
Rv1401|M.tuberculosis_H37Rv --------NLTIPVTVYIVALSAMVCT----------------ALLARLP
MMAR_2210|M.marinum_M --------KLTIPVTVYILVLTAMVCT----------------AFVTRLP
MUL_1796|M.ulcerans_Agy99 --------NLTIPMTVYILVLTAMVCT----------------AFVTRLS
MAV_3376|M.avium_104 --------KLTLPVTLYIVVLTAMVCA----------------ALLAKLP
Mflv_3734|M.gilvum_PYR-GCK --------GMAVPVTAYIGVLGAMVCV----------------ALLADLP
Mvan_2683|M.vanbaalenii_PYR-1 --------GMALPVTVYIAVLGAMVCT----------------ALLADLP
MSMEG_3060|M.smegmatis_MC2_155 --------GMAVPVTAYIAVLGAMVCA----------------ALLAGLP
TH_1437|M.thermoresistible__bu --------GMAVPVTLYIAVLGAMVCA----------------ALLARLP
MAB_4509c|M.abscessus_ATCC_199 ASAVLYAGPLLVIASVLMAATVGMVLATMARVGWASPQSAPTRAVLAGVS
: : : : . .** . *.:: :.
Mb1436|M.bovis_AF2122/97 TIWTAVGAVCFAASDSMIGIGRFILGNEALAVPIWWSYAAAEILITAGFF
Rv1401|M.tuberculosis_H37Rv TIWTAVGAVCFAASDSMIGIGRFILGNEALAVPIWWSYAAAEILITAGFF
MMAR_2210|M.marinum_M TIWTAVGALSFAVSDSMIAISRFILGNEALAVPIWWAYAAAEILITAGFF
MUL_1796|M.ulcerans_Agy99 TIWTAVGALSFAVSDSMIAISRFILGNEALAVPIWWAYAAAEILITAGFF
MAV_3376|M.avium_104 TIWTAVGAVCFAASDSMIAIGRFILGNEALAVPIWWAYAAAQILITAGFF
Mflv_3734|M.gilvum_PYR-GCK TPWTALGAVCFAVSDAMIGINVFVLGSEALAVPIWWVYATSLLLITAGLL
Mvan_2683|M.vanbaalenii_PYR-1 TPWTALGAVCFAVSDAMIGISRFVLGSEALAVPIWWAYATSLLLITAGLL
MSMEG_3060|M.smegmatis_MC2_155 TPWTAAGAVCFAVSDAMIGISEFVRGDQLLAVPIWWAYAASLLLITAGLF
TH_1437|M.thermoresistible__bu TPWTALGAVCFAASDAMIGINKFVLGSEALAVPIWWGYAAALLLITAGFF
MAB_4509c|M.abscessus_ATCC_199 MLYSGTAAVVLSGTALLGNNDGFLLG-HGLATVSWMAVSVALLLAGLRRY
::. .*: :: : : . *: * . **. * :.: :*
Mb1436|M.bovis_AF2122/97 FGREVPDNAAAPTDS-----------------------------------
Rv1401|M.tuberculosis_H37Rv FGREVPDNAAAPTDS-----------------------------------
MMAR_2210|M.marinum_M FGRDISDNGPAAVDG-----------------------------------
MUL_1796|M.ulcerans_Agy99 FGRDISDNGPAAVDG-----------------------------------
MAV_3376|M.avium_104 FGREAAGDAAGEATGDAIGDAVEPVE------------------------
Mflv_3734|M.gilvum_PYR-GCK FGRRSEPSATPAL-------------------------------------
Mvan_2683|M.vanbaalenii_PYR-1 FGRASVPSATPAV-------------------------------------
MSMEG_3060|M.smegmatis_MC2_155 TKRG-----TPAQ-------------------------------------
TH_1437|M.thermoresistible__bu FGRH-----AEAT-------------------------------------
MAB_4509c|M.abscessus_ATCC_199 RGRSWVTRTGFVLAAMAVAKLFLFDLATLDGVARIGAFIVTGLLLLGGGT
*
Mb1436|M.bovis_AF2122/97 --------------------
Rv1401|M.tuberculosis_H37Rv --------------------
MMAR_2210|M.marinum_M --------------------
MUL_1796|M.ulcerans_Agy99 --------------------
MAV_3376|M.avium_104 --------------------
Mflv_3734|M.gilvum_PYR-GCK --------------------
Mvan_2683|M.vanbaalenii_PYR-1 --------------------
MSMEG_3060|M.smegmatis_MC2_155 --------------------
TH_1437|M.thermoresistible__bu --------------------
MAB_4509c|M.abscessus_ATCC_199 LYAREYATRSEEPSAERPVT